Reference on EC 2.7.8.11 - CDP-diacylglycerol-inositol 3-phosphatidyltransferase
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Kuchler, K.; Daum, G.; Paltauf, F.
Subcellular and submitochondrial localization of phospholipid-synthesizing enzymes in Saccharomyces cerevisiae
J. Bacteriol.
165
901-910
1986
Saccharomyces cerevisiae
Whiting, P.H.; Palmano, K.P.; Hawthorne, J.N.
Enzymes of myo-inositol and inositol lipid metabolism in rats with streptozotocin-induced diabetes
Biochem. J.
179
549-553
1979
Rattus, Metazoa
Murthy, P.P.N.; Agranoff, B.W.
Stereospecific synthesis and enzyme studies of CDP-diacylglycerols
Biochim. Biophys. Acta
712
473-483
1982
BRENDA: Cavia porcellus
Textmining: Brassica oleracea var. capitata, snake
Lykidis, A.; Jackson, P.; Rock, C.O.; Jackowski, S.
The role of CDP-diacylglycerol synthetase and phosphatidylinositol synthase activity levels in the regulation of cellular phosphatidylinositol content
J. Biol. Chem.
272
33402-33409
1997
Homo sapiens (O14735), Homo sapiens
Shen, H.; Dowhan, W.
Regulation of phospholipid biosynthetic enzymes by the level of CDP-diacylglycerol synthase activity
J. Biol. Chem.
272
11215-11220
1997
Saccharomyces cerevisiae
Prottey, C.; Hawthorne, J.N.
The biosynthesis of phosphatidic acid and phosphatidylinositol in mammalian pancreas
Biochem. J.
105
379-392
1967
Cavia porcellus
Rao, R.H.; Strickland, K.P.
On the solubility, stability and partial purification of CDPdiacyl-sn-glycerol: inositol transferase from rat brain
Biochim. Biophys. Acta
348
306-314
1974
Rattus norvegicus
Hokin-Neaverson, M.; Sadeghian, K.; Harris, D.W.; Merrin, J.S.
Synthesis of CDP-diglyceride from phosphatidylinositol and CMP
Biochem. Biophys. Res. Commun.
78
364-371
1977
Mus musculus
Takenawa, T.; Egawa, K.
CDP-diglyceride:inositol transferase from rat liver. Purification and properties
J. Biol. Chem.
252
5419-5423
1977
BRENDA: Rattus norvegicus
Textmining: Rattus
Wootton, J.A.; Kinsella, J.E.
Properties of cytidinediphosphodiacyl-sn-glycerol:myoinositol transferase of bovine mammary tissue
Int. J. Biochem.
8
449-456
1977
Bos taurus
-
Sexton, J.S.; Moore, T.S.
Phosphatidylinositol synthesis in castor bean endosperm
Plant Physiol.
62
978-980
1978
Ricinus communis
Bleasdale, J.E.; Wallis, P.; MacDonald, P.C.; Johnston, J.M.
Characterization of the forward and reverse reactions catalyzed by CDP-diacylglycerol:inositol transferase in rabbit lung tissue
Biochim. Biophys. Acta
575
135-147
1979
Oryctolagus cuniculus
Robinson, M.L.; Carman, G.M.
Solubilization of microsomal-associated phosphatidylinositol synthase from germinating soybeans
Plant Physiol.
69
146-149
1982
BRENDA: Glycine max
Textmining: plant
Fischl, A.S.; Carman, G.M.
Phosphatidylinositol biosynthesis in Saccharomyces cerevisiae: purification and properties of microsome-associated phosphatidylinositol synthase
J. Bacteriol.
154
304-311
1983
Saccharomyces cerevisiae
Parries, G.S.; Hokin-Neaverson, M.
Phosphatidylinositol synthase from canine pancreas: solubilization by n-octyl glucopyranoside and stabilization by manganese
Biochemistry
23
4785-4791
1984
Canis lupus familiaris
Parries, G.S.; Hokin-Neaverson, M.
Inhibition of phosphatidylinositol synthase and other membrane-associated enzymes by stereoisomers of hexachlorocyclohexane
J. Biol. Chem.
260
2687-2693
1985
BRENDA: Canis lupus familiaris
Textmining: insertion sequences, Mus musculus
Fischl, A.S.; Homann, M.J.; Poole, M.A.; Carman, G.M.
Phosphatidylinositol synthase from Saccharomyces cerevisiae. Reconstitution, characterization, and regulation of activity
J. Biol. Chem.
261
3178-3183
1986
Saccharomyces cerevisiae
Kasinathan, C.; Kirchberger, M.A.
Presence of a Ca2+-sensitive CDPdiglyceride-inositol transferase in canine cardiac sarcoplasmic reticulum
Biochemistry
27
2834-2839
1988
Canis lupus familiaris
Cubitt, A.B.; Gershengorn, M.C.
Characterization of a salt-extractable phosphatidylinositol synthase from rat pituitary-tumour membranes
Biochem. J.
257
639-644
1989
BRENDA: Rattus norvegicus
Textmining: Rattus
Carman, G.M.; Fischl, A.S.
Phosphatidylinositol synthase from yeast
Methods Enzymol.
209
305-312
1992
Saccharomyces cerevisiae
Imoto, M.; Taniguchi, Y.; Umezawa, K.
Inhibition of CDP-DG: inositol transferase by inostamycin
J. Biochem.
112
299-302
1992
Homo sapiens
Klezovitch, O.; Brandenburger, Y.; Geindre, M.; Deshusses, J.
Characterization of reactions catalysed by yeast phosphatidylinositol synthase
FEBS Lett.
320
256-260
1993
BRENDA: Saccharomyces cerevisiae
Textmining: Escherichia coli
Antonsson, B.E.
Purification and characterization of phosphatidylinositol synthase from human placenta
Biochem. J.
297
517-522
1994
Homo sapiens
-
Elabbadi, N.; Ancelin, M.L.; Vial, H.J.
Characterization of phosphatidylinositol synthase and evidence of a polyphosphoinositide cycle in Plasmodium-infected erythrocytes
Mol. Biochem. Parasitol.
63
179-192
1994
BRENDA: Plasmodium knowlesi
Textmining: Plasmodium
Monaco, M.E.; Feldman, M.; Kleinberg, D.L.
Identification of rat liver phosphatidylinositol synthase as a 21 kDa protein
Biochem. J.
304
301-305
1994
Rattus norvegicus
-
Justin, A.M.; Hmyene, A.; Kader, J.C.; Mazliak, P.
Compared selectivities of the phosphatidylinositol-synthase from maize coleoptiles either in microsomal membranes or after solubilization
Biochim. Biophys. Acta
1255
161-166
1995
Zea mays
Antonsson, B.E.; Klig, L.S.
Candida albicans phosphatidylinositol synthase has common features with both Saccharomyces cerevisiae and mammalian phosphatidylinositol synthases
Yeast
12
449-456
1996
BRENDA: Candida albicans
Textmining: Saccharomyces cerevisiae, Homo sapiens
Antonsson, B.
Phosphatidylinositol synthase from mammalian tissues
Biochim. Biophys. Acta
1348
179-186
1997
Bos taurus, Saccharomyces cerevisiae, Cavia porcellus, Gallus gallus, Oryctolagus cuniculus, Homo sapiens, Meleagris gallopavo, Rattus norvegicus
Nikawa, J.; Yamashita, S.
Phosphatidylinositol synthase from yeast
Biochim. Biophys. Acta
1348
173-178
1997
BRENDA: Saccharomyces cerevisiae, no activity in Escherichia coli, Rattus norvegicus
Textmining: Homo sapiens
Seron, K.; Dzierszinski, F.; Tomavo, S.
Molecular cloning, functional complementation in Saccharomyces cerevisiae and enzymatic properties of phosphatidylinositol synthase from the protozoan parasite Toxoplasma gondii
Eur. J. Biochem.
267
6571-6579
2000
BRENDA: Toxoplasma gondii, Toxoplasma gondii (Q9XY91), Toxoplasma gondii 76K, Toxoplasma gondii 76K (Q9XY91)
Textmining: Saccharomyces cerevisiae, Arabidopsis thaliana, Homo sapiens, Rattus, Metazoa
Xue, H.W.; Hosaka, K.; Plesch, G.; Mueller-Roeber, B.
Cloning of Arabidopsis thaliana phosphatidylinositol synthase and functional expression in the yeast pis mutant
Plant Mol. Biol.
42
757-764
2000
BRENDA: Arabidopsis thaliana, Arabidopsis thaliana (Q8GUK6), no activity in Saccharomyces cerevisiae
Textmining: Saccharomyces cerevisiae, plant, Embryophyta, Metazoa, Mammalia
Deguchi, A.; Segawa, K.; Hosaka, K.; Weinstein, I.B.; Umezawa, K.
Overexpression of phosphatidylinositol synthase enhances growth and G1 progression in NIH3T3 cells
Jpn. J. Cancer Res.
93
157-166
2002
Mus musculus, Rattus norvegicus
Justin, A.M.; Kader, J.C.; Collin, S.
Phosphatidylinositol synthesis and exchange of the inositol head are catalysed by the single phosphatidylinositol synthase 1 from Arabidopsis
Eur. J. Biochem.
269
2347-2352
2002
BRENDA: Arabidopsis thaliana, no activity in Escherichia coli
Textmining: Arabidopsis, Escherichia coli, plant, Glycine max
Norman, R.A.; McAlister, M.S.; Murray-Rust, J.; Movahedzadeh, F.; Stoker, N.G.; McDonald, N.Q.
Crystal structure of inositol 1-phosphate synthase from Mycobacterium tuberculosis, a key enzyme in phosphatidylinositol synthesis
Structure
10
393-402
2002
Mycobacterium tuberculosis
Blouin, A.; Lavezzi, T.; Moore, T.S.
Membrane lipid biosynthesis in Chlamydomonas reinhardtii. Partial characterization of CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase
Plant Physiol. Biochem.
41
11-16
2003
Chlamydomonas reinhardtii
-
Justin, A.M.; Kader, J.C.; Collin, S.
Synthetic capacity of Arabidopsis phosphatidylinositol synthase 1 expressed in Escherichia coli
Biochim. Biophys. Acta
1634
52-60
2003
BRENDA: Arabidopsis thaliana
Textmining: Escherichia coli, Arabidopsis, Bacteria, plant
Nigou, J.; Dover, L.G.; Besra, G.S.
Purification and biochemical characterization of Mycobacterium tuberculosis SuhB, an inositol monophosphatase involved in inositol biosynthesis
Biochemistry
41
4392-4398
2002
Corynebacteriales
Kordulakova, J.; Gilleron, M.; Mikusova, K.; Puzo, G.; Brennan, P.J.; Gicquel, B.; Jackson, M.
Definition of the first mannosylation step in phosphatidylinositol: Mannoside Synthesis. PimA IS essential for growth of mycobacteria
J. Biol. Chem.
277
31335-31344
2002
Mycolicibacterium smegmatis, Mycolicibacterium smegmatis (A0QWG6), Mycobacterium tuberculosis
Han, S.H.; Han, G.S.; Iwanyshyn, W.M.; Carman, G.M.
Regulation of the PIS1-encoded phosphatidylinositol synthase in Saccharomyces cerevisiae by zinc
J. Biol. Chem.
280
29017-29024
2005
Saccharomyces cerevisiae
Das, S.; Hussain, A.; Bock, C.; Keller, W.A.; Georges, F.
Cloning of Brassica napus phospholipase C2 (BnPLC2), phosphatidylinositol 3-kinase (BnVPS34) and phosphatidylinositol synthase1 (BnPtdIns S1) - comparative analysis of the effect of abiotic stresses on the expression of phosphatidylinositol signal transduction-related genes in B. napus
Planta
220
777-784
2005
BRENDA: Brassica napus (Q8H1S8), Brassica napus
Textmining: Arabidopsis
Martin, K.L.; Smith, T.K.
Phosphatidylinositol synthesis is essential in bloodstream form Trypanosoma brucei
Biochem. J.
396
287-295
2006
Trypanosoma brucei (Q6KBS8)
Riggs, B.M.; Lansley, T.A.; Ryals, P.E.
Phosphatidylinositol synthase of Tetrahymena: inositol isomers as substrates in phosphatidylinositol biosynthesis and headgroup exchange reactions
J. Eukaryot. Microbiol.
54
119-124
2007
BRENDA: Tetrahymena vorax, Tetrahymena vorax V2S
Textmining: Tetrahymena
Wengelnik, K.; Vial, H.J.
Characterisation of the phosphatidylinositol synthase gene of Plasmodium species
Res. Microbiol.
158
51-59
2007
BRENDA: Plasmodium falciparum (C0H5B7), Plasmodium falciparum (Q2MJB9), Plasmodium falciparum, Plasmodium knowlesi (Q2MJB8), Plasmodium knowlesi
Textmining: Plasmodium, Saccharomyces cerevisiae, Plasmodium chabaudi
Loefke, C.; Ischebeck, T.; Koenig, S.; Freitag, S.; Heilmann, I.
Alternative metabolic fates of phosphatidylinositol produced by phosphatidylinositol synthase isoforms in Arabidopsis thaliana
Biochem. J.
413
115-124
2008
BRENDA: Arabidopsis thaliana (Q8GUK6), Arabidopsis thaliana (Q8LBA6), Arabidopsis thaliana
Textmining: Arabidopsis, Allium cepa
Morii, H.; Kiyonari, S.; Ishino, Y.; Koga, Y.
A novel biosynthetic pathway of archaetidyl-myo-inositol via archaetidyl-myo-inositol phosphate from CDP-archaeol and D-glucose 6-phosphate in methanoarchaeon Methanothermobacter thermautotrophicus cells
J. Biol. Chem.
284
30766-30774
2009
Escherichia coli, Saccharomyces cerevisiae
Murphy, T.R.; Vihtelic, T.S.; Ile, K.E.; Watson, C.T.; Willer, G.B.; Gregg, R.G.; Bankaitis, V.A.; Hyde, D.R.
Phosphatidylinositol synthase is required for lens structural integrity and photoreceptor cell survival in the zebrafish eye
Exp. Eye Res.
93
460-474
2011
BRENDA: Danio rerio
Textmining: Saccharomyces cerevisiae
Davy de Virville, J.; Brown, S.; Cochet, F.; Soler, M.N.; Hoffelt, M.; Ruelland, E.; Zachowski, A.; Collin, S.
Assessment of mitochondria as a compartment for phosphatidylinositol synthesis in Solanum tuberosum
Plant Physiol. Biochem.
48
952-960
2010
BRENDA: Solanum tuberosum
Textmining: Saccharomyces cerevisiae
Zhai, S.M.; Gao, Q.; Xue, H.W.; Sui, Z.H.; Yue, G.D.; Yang, A.F.; Zhang, J.R.
Overexpression of the phosphatidylinositol synthase gene from Zea mays in tobacco plants alters the membrane lipids composition and improves drought stress tolerance
Planta
235
69-84
2012
BRENDA: Zea mays
Textmining: Nicotiana tabacum, Saccharomyces cerevisiae, Metazoa
Morii, H.; Ogawa, M.; Fukuda, K.; Taniguchi, H.
Ubiquitous distribution of phosphatidylinositol phosphate synthase and archaetidylinositol phosphate synthase in bacteria and archaea, which contain inositol phospholipid
Biochem. Biophys. Res. Commun.
443
86-90
2013
BRENDA: Homo sapiens, Saccharomyces cerevisiae (P70500), Saccharomyces cerevisiae
Textmining: Bacteria, Archaea, Corynebacterium glutamicum, Cutibacterium acnes, Rhodococcus, Pyrococcus, Sulfolobus, eukaryota, Methanothermobacter
Bochud, A.; Conzelmann, A.
The active site of yeast phosphatidylinositol synthase Pis1 is facing the cytosol
Biochim. Biophys. Acta
1851
629-640
2015
Saccharomyces cerevisiae (P06197), Saccharomyces cerevisiae, Saccharomyces cerevisiae BY4742 (P06197)
Liu, X.; Zhai, S.; Zhao, Y.; Sun, B.; Liu, C.; Yang, A.; Zhang, J.
Overexpression of the phosphatidylinositol synthase gene (ZmPIS) conferring drought stress tolerance by altering membrane lipid composition and increasing ABA synthesis in maize
Plant Cell Environ.
36
1037-1055
2013
BRENDA: Zea mays (Q6UG58), Zea mays, Zea mays DH4866 (Q6UG58)
Textmining: plant
Morii, H.; Ogawa, M.; Fukuda, K.; Taniguchi, H.
Ubiquitous distribution of phosphatidylinositol phosphate synthase and archaetidylinositol phosphate synthase in Bacteria and Archaea, which contain inositol phospholipid
Biochem. Biophys. Res. Commun.
443
86-90
2014
Saccharomyces cerevisiae, Homo sapiens, Bacteria, Archaea, Corynebacterium glutamicum, Cutibacterium acnes, Rhodococcus, Pyrococcus, Sulfolobus, eukaryota, Methanothermobacter
Yamagami, K.; Yamamoto, T.; Sakai, S.; Mioka, T.; Sano, T.; Igarashi, Y.; Tanaka, K.
Inositol depletion restores vesicle transport in yeast phospholipid flippase mutants
PLoS ONE
10
e0120108
2015
Saccharomyces cerevisiae
Long, Q.; Yue, F.; Liu, R.; Song, S.; Li, X.; Ding, B.; Yan, X.; Pei, Y.
The phosphatidylinositol synthase gene (GhPIS) contributes to longer, stronger, and finer fibers in cotton
Mol. Genet. Genomics
293
1139-1149
2018
Gossypium hirsutum (A0A075T0L0), Gossypium hirsutum
Philippe, RN; Ralph, SG; Külheim, C; Jancsik, SI; Bohlmann, J
Poplar defense against insects: genome analysis, full-length cDNA cloning, and transcriptome and protein analysis of the poplar Kunitz-type protease inhibitor family.
New Phytol
2009
Populus, plant
Baker, RR; Chang, H
Phosphatidylinositol synthetase activities in neuronal nuclei and microsomal fractions isolated from immature rabbit cerebral cortex.
Biochim Biophys Acta
1042
55-61
1990
Oryctolagus cuniculus
Ghalayini, A; Eichberg, J
Purification of phosphatidylinositol synthetase from rat brain by CDP-diacylglycerol affinity chromatography and properties of the purified enzyme.
J Neurochem
44
175-82
1985
Rattus
Bas, N; Garcia, A
Effect of deoxycholate on guanine-nucleotide-dependent carbachol stimulation of phosphoinositidase C in mouse brain cortical membranes.
Biochem J
312 ( Pt 2)
445-9
1995
Mus musculus
Saito, S; Sakagami, H; Tonosaki, A; Kondo, H
Localization of mRNAs for CDP-diacylglycerol synthase and phosphatidylinositol synthase in the brain and retina of developing and adult rats.
Brain Res Dev Brain Res
110
21-30
1998
Rattus
Bae-Lee, M; Carman, GM
Regulation of yeast phosphatidylserine synthase and phosphatidylinositol synthase activities by phospholipids in Triton X-100/phospholipid mixed micelles.
J Biol Chem
265
7221-6
1990
Saccharomyces cerevisiae
Carman, GM; Matas, J
Solubilization of microsomal-associated phosphatidylserine synthase and phosphatidylinositol synthase from Saccharomyces cerevisiae.
Can J Microbiol
27
1140-9
1981
Saccharomyces cerevisiae
Bleasdale, JE; Wallis, P; MacDonald, PC; Johnston, JM
Changes in CDP-diglyceride:inositol transferase activity during rabbit lung development.
Pediatr Res
13
1182-3
1979
Oryctolagus cuniculus
Nakamura, J; Del Monte, MA; Shewach, D; Lattimer, SA; Greene, DA
Inhibition of phosphatidylinositol synthase by glucose in human retinal pigment epithelial cells.
Am J Physiol
262
E417-26
1992
Homo sapiens
McPhee, F; Lowe, G; Vaziri, C; Downes, CP
Phosphatidylinositol synthase and phosphatidylinositol/inositol exchange reactions in turkey erythrocyte membranes.
Biochem J
275 ( Pt 1)
187-92
1991
Meleagris gallopavo, Phasianidae, Homo sapiens
Cubitt, AB; Gershengorn, MC
CMP activates reversal of phosphatidylinositol synthase and base exchange by distinct mechanisms in rat pituitary GH3 cells.
Biochem J
272
813-6
1990
Rattus
Nikawa, J; Kodaki, T; Yamashita, S
Primary structure and disruption of the phosphatidylinositol synthase gene of Saccharomyces cerevisiae.
J Biol Chem
262
4876-81
1987
Saccharomyces cerevisiae, Escherichia coli, insertion sequences
Imai, A; Gershengorn, MC
Regulation by phosphatidylinositol of rat pituitary plasma membrane and endoplasmic reticulum phosphatidylinositol synthase activities. A mechanism for activation of phosphoinositide resynthesis during cell stimulation.
J Biol Chem
262
6457-9
1987
Rattus
Kumano, Y; Nikawa, J
Functional analysis of mutations in the PIS gene, which encodes Saccharomyces cerevisiae phosphatidylinositol synthase.
FEMS Microbiol Lett
126
81-4
1995
Escherichia coli, Saccharomyces cerevisiae
Monaco, ME; Feldman, M; Kleinberg, DL
Identification of rat liver phosphatidylinositol synthase as a 21 kDa protein.
Biochem J
304 ( Pt 1)
301-5
1994
Rattus
Antonsson, BE
Purification and characterization of phosphatidylinositol synthase from human placenta.
Biochem J
297 ( Pt 3)
517-22
1994
Homo sapiens
Vaziri, C; Downes, CP; Macfarlane, SC
Direct labelling of hormone-sensitive phosphoinositides by a plasma-membrane-associated PtdIns synthase in turkey erythrocytes.
Biochem J
294 ( Pt 3)
793-9
1993
Meleagris gallopavo
Tanaka, S; Nikawa, J; Imai, H; Yamashita, S; Hosaka, K
Molecular cloning of rat phosphatidylinositol synthase cDNA by functional complementation of the yeast Saccharomyces cerevisiae pis mutation.
FEBS Lett
393
89-92
1996
Saccharomyces cerevisiae, Rattus
Collin, S; Justin, AM; Cantrel, C; Arondel, V; Kader, JC
Identification of AtPIS, a phosphatidylinositol synthase from Arabidopsis.
Eur J Biochem
262
652-8
1999
Arabidopsis, Bacteria, Escherichia coli, plant, Saccharomyces cerevisiae
Fu, CZ; Wang, H; Mei, CG; Wang, JL; Jiang, BJ; Ma, XH; Wang, HB; Cheng, G; Zan, LS
SNPs at 3'-UTR of the bovine CDIPT gene associated with Qinchuan cattle meat quality traits.
Genet Mol Res
12
775-82
2013
Bos taurus
Collin, S; Cochet, F
Phosphatidylinositol synthase activity from plant membrane fractions and from E. coli-expressed recombinant peptides.
Methods Mol Biol
1009
145-61
2013
plant, Escherichia coli
Zhang, H; Hou, J; Jiang, P; Qi, S; Xu, C; He, Q; Ding, Z; Wang, Z; Zhang, K; Li, K
Identification of a 467 bp Promoter of Maize Phosphatidylinositol Synthase Gene (ZmPIS) Which Confers High-Level Gene Expression and Salinity or Osmotic Stress Inducibility in Transgenic Tobacco.
Front Plant Sci
7
42
2016
Nicotiana tabacum, Zea mays, plant
Gaigg, B; Simbeni, R; Hrastnik, C; Paltauf, F; Daum, G
Characterization of a microsomal subfraction associated with mitochondria of the yeast, Saccharomyces cerevisiae. Involvement in synthesis and import of phospholipids into mitochondria.
Biochim Biophys Acta
1234
214-20
1995
Saccharomyces cerevisiae, eukaryota
Ferreira-Neto, JRC; da Silva, MD; Rodrigues, FA; Nepomuceno, AL; Pandolfi, V; de Lima Morais, DA; Kido, EA; Benko-Iseppon, AM
Importance of inositols and their derivatives in cowpea under root dehydration: An omics perspective.
Physiol Plant
172
441-462
2021
Vigna unguiculata
Leber, A; Hrastnik, C; Daum, G
Phospholipid-synthesizing enzymes in Golgi membranes of the yeast, Saccharomyces cerevisiae.
FEBS Lett
377
271-4
1995
Saccharomyces cerevisiae
Ishikawa, A; Ohta, S; Matsuoka, K; Hattori, T; Nakamura, K
A family of potato genes that encode Kunitz-type proteinase inhibitors: structural comparisons and differential expression.
Plant Cell Physiol
35
303-12
1994
Ipomoea batatas
Kato, K; Thomas, TP; Stevens, MJ; Greene, DA; Nakamura, J
2-Chloroadenosine reverses hyperglycemia-induced inhibition of phosphoinositide synthesis in cultured human retinal pigment epithelial cells and prevents reduced nerve conduction velocity in diabetic rats.
Metabolism
48
827-33
1999
Homo sapiens, Rattus
Homann, MJ; Poole, MA; Gaynor, PM; Ho, CT; Carman, GM
Effect of growth phase on phospholipid biosynthesis in Saccharomyces cerevisiae.
J Bacteriol
169
533-9
1987
Saccharomyces cerevisiae
Morii, H; Ogawa, M; Fukuda, K; Taniguchi, H; Koga, Y
A revised biosynthetic pathway for phosphatidylinositol in Mycobacteria.
J Biochem
148
593-602
2010
Corynebacteriales, Saccharomyces cerevisiae, Escherichia coli, Mycolicibacterium smegmatis
Sarri, E; Picatoste, F; Claro, E
Neurotransmitter-stimulated breakdown of endogenous polyphosphoinositides in post mortem human brain.
Neuroreport
5
1059-62
1994
Homo sapiens
Salman, M; Lonsdale, JT; Besra, GS; Brennan, PJ
Phosphatidylinositol synthesis in mycobacteria.
Biochim Biophys Acta
1436
437-50
1999
Corynebacteriales, Mycolicibacterium smegmatis, Saccharomyces cerevisiae, Rattus
Meijer, HJ; Govers, F
Genomewide analysis of phospholipid signaling genes in Phytophthora spp.: novelties and a missing link.
Mol Plant Microbe Interact
19
1337-47
2006
Phytophthora, eukaryota, Oomycota, Phytophthora sojae, Phytophthora ramorum
Nikawa, J; Kodaki, T; Yamashita, S
Expression of the Saccharomyces cerevisiae PIS gene and synthesis of phosphatidylinositol in Escherichia coli.
J Bacteriol
170
4727-31
1988
Escherichia coli, Saccharomyces cerevisiae
Homann, MJ; Bailis, AM; Henry, SA; Carman, GM
Coordinate regulation of phospholipid biosynthesis by serine in Saccharomyces cerevisiae.
J Bacteriol
169
3276-80
1987
Saccharomyces cerevisiae
Gould, RM; Spivack, WD; Robertson, D; Poznansky, MJ
Phospholipid synthesis in the squid giant axon: enzymes of phosphatidylinositol metabolism.
J Neurochem
40
1300-6
1983
Doryteuthis pealeii
Kinney, AJ; Carman, GM
Enzymes of phosphoinositide synthesis in secretory vesicles destined for the plasma membrane in Saccharomyces cerevisiae.
J Bacteriol
172
4115-7
1990
Saccharomyces cerevisiae
Ren, B; Kong, P; Hedar, F; Brouwers, JF; Gupta, N
Phosphatidylinositol synthesis, its selective salvage, and inter-regulation of anionic phospholipids in Toxoplasma gondii.
Commun Biol
3
750
2020
Toxoplasma gondii, Toxoplasma, Homo sapiens
Gaynor, PM; Greenberg, ML
Regulation of CDP-diacylglycerol synthesis and utilization by inositol and choline in Schizosaccharomyces pombe.
J Bacteriol
174
5711-8
1992
Schizosaccharomyces pombe, Saccharomyces cerevisiae
Homann, MJ; Carman, GM
Detection of phospholipid biosynthetic enzyme activities in Saccharomyces cerevisiae by colony autoradiography.
Anal Biochem
135
447-52
1983
Saccharomyces cerevisiae
Piatti, E; Piacentini, MP; Fraternale, D; Bucchini, A; Mangani, F; Accorsi, A
myo-[3H]-inositol loaded erythrocytes and white ghosts: two models to investigate the phosphatidylinositol synthesis in human red cells.
Biochimie
81
1011-4
1999
Homo sapiens
Carman, GM; Han, GS
Regulation of phospholipid synthesis in Saccharomyces cerevisiae by zinc depletion.
Biochim Biophys Acta
1771
322-30
2007
Saccharomyces cerevisiae
Ohno, T; Imai, A; Furui, T; Matsunami, K; Matsuda, T; Tamaya, T
Evidence of a role for phosphatidylinositol synthesis in human amnion cell proliferation.
Biol Reprod
47
730-5
1992
Homo sapiens
Kozloff, LM; Turner, MA; Arellano, F; Lute, M
Phosphatidylinositol, a phospholipid of ice-nucleating bacteria.
J Bacteriol
173
2053-60
1991
Bacteria, Pseudomonas, Pseudomonas syringae, Pantoea agglomerans, Erwinia, Escherichia coli, plasmids, Escherichia coli K-12, Emberizoides herbicola
Gibson, A; Brammer, MJ
The influence of divalent cations and substrate concentration on the incorporation of myo-inositol into phospholipids of isolated bovine oligodendrocytes.
J Neurochem
36
868-74
1981
Bos taurus
Mitsumori, C; Yamagishi, K; Fujino, K; Kikuta, Y
Detection of immunologically related Kunitz and Bowman-Birk proteinase inhibitors expressed during potato tuber development.
Plant Mol Biol
26
961-9
1994
Solanum tuberosum, Tuber
Anderson, MS; Lopes, JM
Carbon source regulation of PIS1 gene expression in Saccharomyces cerevisiae involves the MCM1 gene and the two-component regulatory gene, SLN1.
J Biol Chem
271
26596-601
1996
Saccharomyces cerevisiae
Jackson, M; Crick, DC; Brennan, PJ
Phosphatidylinositol is an essential phospholipid of mycobacteria.
J Biol Chem
275
30092-9
2000
Corynebacteriales, Mycobacterium, Mycolicibacterium smegmatis, Mycobacterium tuberculosis, Mycobacterium sp., bacterium
Rohatgi, N; Matta, A; Kaur, J; Srivastava, A; Ralhan, R
Novel molecular targets of smokeless tobacco (khaini) in cell culture from oral hyperplasia.
Toxicology
224
1-13
2006
Transformation
Iverson, S; Sonnemann, K; Reddick, A; McDonough, V
Expression of the Saccharomyces cerevisiae PIS1 gene is modulated by multiple ATGs in the promoter.
Biochem Biophys Res Commun
350
91-6
2006
Saccharomyces cerevisiae
Kozloff, LM; Lute, M; Westaway, D
Phosphatidylinositol as a Component of the Ice Nucleating Site of Pseudomonas syringae and Erwinia herbiola.
Science
226
845-846
1984
Bacteria, Erwinia, Escherichia coli, plasmids, Pseudomonas
Thakur, PC; Stuckenholz, C; Rivera, MR; Davison, JM; Yao, JK; Amsterdam, A; Sadler, KC; Bahary, N
Lack of de novo phosphatidylinositol synthesis leads to endoplasmic reticulum stress and hepatic steatosis in cdipt-deficient zebrafish.
Hepatology
54
452-62
2011
Danio rerio
Thakur, PC; Davison, JM; Stuckenholz, C; Lu, L; Bahary, N
Dysregulated phosphatidylinositol signaling promotes endoplasmic-reticulum-stress-mediated intestinal mucosal injury and inflammation in zebrafish.
Dis Model Mech
7
93-106
2014
Danio rerio, Homo sapiens
Smith, L; Fabian, L; Al-Maawali, A; Noche, RR; Dowling, JJ
De novo phosphoinositide synthesis in zebrafish is required for triad formation but not essential for myogenesis.
PLoS One
15
e0231364
2020
Danio rerio, Homo sapiens
Galvao, C; Shayman, JA
The phosphatidylinositol synthase of proximal tubule cells.
Biochim Biophys Acta
1044
34-42
1990
Oryctolagus cuniculus
Johnson, SC; Dahl, J; Shih, TL; Schedler, DJ; Anderson, L; Benjamin, TL; Baker, DC
Synthesis and evaluation of 3-modified 1D-myo-inositols as inhibitors and substrates of phosphatidylinositol synthase and inhibitors of myo-inositol uptake by cells.
J Med Chem
36
3628-35
1993
Mus musculus
Daiyasu, H; Kuma, K; Yokoi, T; Morii, H; Koga, Y; Toh, H
A study of archaeal enzymes involved in polar lipid synthesis linking amino acid sequence information, genomic contexts and lipid composition.
Archaea
1
399-410
2005
Bacteria, eukaryota
Cubitt, AB; Thaw, CN; Gershengorn, MC
5'-CMP stimulates phospholipase A-mediated hydrolysis of phosphatidylinositol in permeabilized pituitary GH3 cells.
Biochem J
278 ( Pt 3)
831-4
1991
Rattus
Slomiany, A; Grabska, M; Piotrowski, E; Sengupta, S; Morita, M; Kasinathan, C; Slomiany, BL
Intracellular processes associated with vesicular transport from endoplasmic reticulum to Golgi and exocytosis: ethanol-induced changes in membrane biogenesis.
Arch Biochem Biophys
310
247-55
1994
Metazoa, Rattus
Rebecchi, MJ; Eberhardt, R; Delaney, T; Ali, S; Bittman, R
Hydrolysis of short acyl chain inositol lipids by phospholipase C-delta 1.
J Biol Chem
268
1735-41
1993
Saccharomyces cerevisiae, Bos taurus
Umezawa, K; Deguchi, A; Imoto, M
[Screening of phosphatidylinositol turnover inhibitors and regulation of cell cycle progression]
Gan To Kagaku Ryoho
24
1578-84
1997
Streptomyces
Garcia, CRS; Alves, E; Pereira, PHS; Bartlett, PJ; Thomas, AP; Mikoshiba, K; Plattner, H; Sibley, LD
InsP3 Signaling in Apicomplexan Parasites.
Curr Top Med Chem
17
2158-2165
2017
Apicomplexa
Hnninen, S; Batchu, KC; Hokynar, K; Somerharju, P
Simple and rapid biochemical method to synthesize labeled or unlabeled phosphatidylinositol species.
J Lipid Res
58
1259-1264
2017
Arabidopsis thaliana, Escherichia coli, Streptomyces chromofuscus
Wan, H; Wang, Q; Chen, X; Zeng, Q; Shao, Y; Fang, H; Liao, X; Li, HS; Liu, MG; Xu, TL; Diao, M; Li, D; Meng, B; Tang, B; Zhang, Z; Liao, L
WDR45 contributes to neurodegeneration through regulation of ER homeostasis and neuronal death.
Autophagy
1-17
2019
Hippocampus
Lpez-Lezama, JC; Cabeza, M; Mayorga, I; Soriano, J; Sainz, T; Bratoeff, E
Effect of Carbamates on mRNA Encoding Lipid Enzymes in Hamster Flank Organs.
Arch Pharm (Weinheim)
2014
Cricetinae
Moore, JP; Smith, GA; Hesketh, TR; Metcalfe, JC
The bivalent-cation dependence of phosphatidylinositol synthesis in a cell-free system from lymphocytes.
Biochem J
212
691-7
1983
Sus scrofa
Kaur, J; Sawhney, M; Dattagupta, S; Shukla, NK; Srivastava, A; Ralhan, R
Clinical Significance of Phosphatidyl Inositol Synthase Overexpression in Oral Cancer.
BMC Cancer
10
168
2010
clinical samples, Nicotiana tabacum
Poole, MA; Fischl, AS; Carman, GM
Enzymatic detection of phospholipid biosynthetic enzymes after electroblotting.
J Bacteriol
161
772-4
1985
Saccharomyces cerevisiae
Kumara-Siri, MH; Gould, RM
Enzymes of phospholipid synthesis: axonal versus Schwann cell distribution.
Brain Res
186
315-30
1980
Mus musculus, Rattus
Imai, A; Gershengorn, MC
Independent phosphatidylinositol synthesis in pituitary plasma membrane and endoplasmic reticulum.
Nature
325
726-8
0
Rattus
Santiago, OM; Rosenberg, LI; Monaco, ME
Organization of the phosphoinositide cycle. Assessment of inositol transferase activity in purified plasma membranes.
Biochem J
290 ( Pt 1)
179-83
1993
Rattus
Gardocki, ME; Jani, N; Lopes, JM
Phosphatidylinositol biosynthesis: biochemistry and regulation.
Biochim Biophys Acta
1735
89-100
2005
eukaryota, Saccharomyces, Saccharomyces cerevisiae
html completed
