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Information on EC 2.7.7.85 - diadenylate cyclase and Organism(s) Listeria monocytogenes serovar 1/2a and UniProt Accession Q8Y5E4

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EC Tree
     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.7 Nucleotidyltransferases
                2.7.7.85 diadenylate cyclase
IUBMB Comments
Cyclic di-3',5'-adenylate is a bioactive molecule produced by some bacteria and archaea, which may function as a secondary signalling molecule . The intracellular bacterial pathogen Listeria monocytogenes secretes it into the host's cytosol, where it triggers a cytosolic pathway of innate immunity .
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Listeria monocytogenes serovar 1/2a
UNIPROT: Q8Y5E4
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Archaea
Synonyms
diadenylate cyclase, dna integrity scanning protein, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
cyclic-di-AMP synthase
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dacA
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disA
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SYSTEMATIC NAME
IUBMB Comments
ATP:ATP adenylyltransferase (cyclizing)
Cyclic di-3',5'-adenylate is a bioactive molecule produced by some bacteria and archaea, which may function as a secondary signalling molecule [1]. The intracellular bacterial pathogen Listeria monocytogenes secretes it into the host's cytosol, where it triggers a cytosolic pathway of innate immunity [2].