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Information on EC 2.7.7.7 - DNA-directed DNA polymerase and Organism(s) Desulfurococcus sp. and UniProt Accession Q7SIG7

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EC Tree
     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.7 Nucleotidyltransferases
                2.7.7.7 DNA-directed DNA polymerase
IUBMB Comments
Catalyses DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time. Cannot initiate a chain de novo. Requires a primer, which may be DNA or RNA. See also EC 2.7.7.49 RNA-directed DNA polymerase.
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This record set is specific for:
Desulfurococcus sp.
UNIPROT: Q7SIG7
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Word Map
The taxonomic range for the selected organisms is: Desulfurococcus sp.
The enzyme appears in selected viruses and cellular organisms
Synonyms
dna polymerase alpha, dna polymerase beta, dna polymerase iii, pol beta, klenow fragment, dna polymerase delta, taq dna polymerase, pol delta, pol alpha, dna polymerase gamma, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
deoxynucleate polymerase
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-
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deoxyribonucleate nucleotidyltransferase
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-
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deoxyribonucleic acid duplicase
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deoxyribonucleic acid polymerase
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deoxyribonucleic duplicase
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deoxyribonucleic polymerase
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deoxyribonucleic polymerase I
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DNA duplicase
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DNA nucleotidyltransferase
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DNA nucleotidyltransferase (DNA-directed)
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DNA polmerase beta
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DNA polymerase
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DNA polymerase alpha
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DNA polymerase gamma
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DNA polymerase I
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-
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DNA polymerase II
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-
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DNA polymerase III
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DNA replicase
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-
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DNA-dependent DNA polymerase
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duplicase
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Klenow fragment
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nucleotidyltransferase, deoxyribonucleate
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Pol gamma
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sequenase
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Taq DNA polymerase
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Taq Pol I
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Tca DNA polymerase
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
nucleotidyl group transfer
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-
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-
SYSTEMATIC NAME
IUBMB Comments
deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed)
Catalyses DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time. Cannot initiate a chain de novo. Requires a primer, which may be DNA or RNA. See also EC 2.7.7.49 RNA-directed DNA polymerase.
CAS REGISTRY NUMBER
COMMENTARY hide
9012-90-2
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
UniProt
Manually annotated by BRENDA team
CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
vapor diffusion at 20°C, crystal structure of is determined at 2.4 A resolution
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Zhao, Y.; Jeruzalmi, D.; Moarefi, I.; Leighton, L.; Lasken, R.; Kuriyan, J.
Crystal structure of an archaebacterial DNA polymerase
Structure
7
1189-1199
1999
Desulfurococcus sp. (Q7SIG7), Desulfurococcus sp. Tok (Q7SIG7)
Manually annotated by BRENDA team