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Information on EC 2.7.7.49 - RNA-directed DNA polymerase and Organism(s) Human immunodeficiency virus type 1 group M subtype B and UniProt Accession P04585

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EC Tree
IUBMB Comments
Catalyses RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time. Cannot initiate a chain de novo. Requires an RNA or DNA primer. DNA can also serve as template. See also EC 2.7.7.7 DNA-directed DNA polymerase.
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Human immunodeficiency virus type 1 group M subtype B
UNIPROT: P04585
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Word Map
The enzyme appears in selected viruses and cellular organisms
Synonyms
telomerase, reverse-transcriptase, telomerase reverse transcriptase, nucleoside reverse transcriptase, hiv-1 rt, hiv-1 reverse transcriptase, gag-pol, hiv reverse transcriptase, rna-dependent dna polymerase, telomerase catalytic subunit, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
DNA nucleotidyltransferase (RNA-directed)
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MX162-RT
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MX65-RT
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nucleotidyltransferase, deoxyribonucleate, RNA-dependent
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P72
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reverse transcriptase
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revertase
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RNA revertase
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RNA-dependent DNA polymerase
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RNA-instructed DNA polymerase
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RT
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telomerase catalytic subunit
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telomerase reverse transcriptase
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
nucleotidyl group transfer
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SYSTEMATIC NAME
IUBMB Comments
deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (RNA-directed)
Catalyses RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time. Cannot initiate a chain de novo. Requires an RNA or DNA primer. DNA can also serve as template. See also EC 2.7.7.7 DNA-directed DNA polymerase.
CAS REGISTRY NUMBER
COMMENTARY hide
9068-38-6
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