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Information on EC 2.7.7.38 - 3-deoxy-manno-octulosonate cytidylyltransferase and Organism(s) Arabidopsis thaliana and UniProt Accession Q9C920

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Arabidopsis thaliana
UNIPROT: Q9C920 not found.
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The taxonomic range for the selected organisms is: Arabidopsis thaliana
The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota
Synonyms
cmp-kdo synthetase, 3-deoxy-manno-octulosonate cytidylyltransferase, 3-deoxy-d-manno-octulosonate cytidylyltransferase, ctp:cmp-3-deoxy-d-manno-octulosonate cytidylyltransferase, l-cks, cmp/kdo synthase, cmp:kdo synthase, 2-keto-3-deoxy-d-manno-octulosonate cytidylyltransferase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
2-keto-3-deoxyoctonate cytidylyltransferase
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3-deoxy-D-manno-octulosonate cytidylyltransferase
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CMP-3-deoxy-D-manno-octulosonate pyrophosphorylase
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CMP-3-deoxy-D-manno-octulosonate synthetase
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CMP-KDO synthetase
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CTP:CMP-3-deoxy-D-manno-octulosonate cytidylyltransferase
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cytidine monophospho-3-deoxy-D-manno-octulosonate pyrophosphorylase
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cytidine monophospho-3-deoxy-D-manno-octulosonate synthetase
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
nucleotidyl group transfer
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PATHWAY SOURCE
PATHWAYS
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SYSTEMATIC NAME
IUBMB Comments
CTP:3-deoxy-D-manno-octulosonate cytidylyltransferase
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CAS REGISTRY NUMBER
COMMENTARY hide
37278-28-7
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
CTP + 3-deoxy-D-manno-octulosonate
diphosphate + CMP-3-deoxy-D-manno-octulosonate
show the reaction diagram
dCTP + 3-deoxy-D-manno-octulosonate
diphosphate + dCMP-3-deoxy-D-manno-octulosonate
show the reaction diagram
about 10% of the activity with CTP
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-
?
UTP + 3-deoxy-D-manno-octulosonate
diphosphate + UMP-3-deoxy-D-manno-octulosonate
show the reaction diagram
about 60% of the activity with CTP
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-
?
CTP + 3-deoxy-D-manno-octulosonate
diphosphate + CMP-3-deoxy-D-manno-octulosonate
show the reaction diagram
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r
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
CTP + 3-deoxy-D-manno-octulosonate
diphosphate + CMP-3-deoxy-D-manno-octulosonate
show the reaction diagram
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r
CTP + 3-deoxy-D-manno-octulosonate
diphosphate + CMP-3-deoxy-D-manno-octulosonate
show the reaction diagram
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r
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
mutation of the KDO gene renders pollen infertile through the inhibition of pollen tube elongation. Results suggest that KDO is an indispensable component of RG-II, and that the complete B-RG-II complex is essential for the cell wall integrity of rapidly growing tissues
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
KDSB_ARATH
290
1
32245
Swiss-Prot
Chloroplast (Reliability: 3)
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expression in Escherichia coli
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Royo, J.; Gomez, E.; Hueros, G.
CMP-KDO synthetase. A plant gene borrowed from Gram-negative eubacteria
Trends Genet.
16
432-433
2000
Aggregatibacter actinomycetemcomitans, Aquifex pyrophilus, Arabidopsis thaliana, Chlamydia pneumoniae, Chlamydia trachomatis, Chlorobaculum tepidum, Escherichia coli, Haemophilus influenzae, Helicobacter pylori, Homo sapiens, Neisseria meningitidis, no activity in Caenorhabditis elegans, no activity in Drosophila melanogaster, no activity in Saccharomyces cerevisiae, Rickettsia prowazekii, Solanum lycopersicum, Vibrio cholerae serotype O1, Yersinia pestis, Zea mays
Manually annotated by BRENDA team
Bravo, I.G.; Reglero, A.
The cytidyltransferases family: Properties, kinetics, genomic and phylogeny
Recent Res. Devel. Biochem.
4
224-254
2003
Aquifex aeolicus, Arabidopsis thaliana (Q9C920), Caulobacter vibrioides (Q9A4A3), Chlamydia muridarum, Chlamydia pneumoniae, Chlamydia trachomatis, Escherichia coli, Escherichia coli (P42216), Haemophilus influenzae, Helicobacter pylori, Mesorhizobium loti (Q98BN3), Neisseria meningitidis, Neisseria meningitidis (Q9K0D6), Neisseria meningitidis MC58 (Q9K0D6), Pasteurella multocida, Pseudomonas aeruginosa, Rickettsia conorii (Q92I96), Rickettsia prowazekii, Salmonella enterica subsp. enterica serovar Typhimurium, Sinorhizobium meliloti (Q92SX6), Vibrio cholerae (Q9KQX2), Xylella fastidiosa (Q9PB46), Zea mays, Zea mays (Q9M4D3), Zea mays (Q9M4G3)
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Manually annotated by BRENDA team
Kobayashi, M.; Kouzu, N.; Inami, A.; Toyooka, K.; Konishi, Y.; Matsuoka, K.; Matoh, T.
Characterization of Arabidopsis CTP:3-deoxy-D-manno-2-octulosonate cytidylyltransferase (CMP-KDO synthetase), the enzyme that activates KDO during rhamnogalacturonan II biosynthesis
Plant Cell Physiol.
52
1832-1843
2011
Arabidopsis thaliana (Q9C920)
Manually annotated by BRENDA team