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Information on EC 2.7.6.2 - thiamine diphosphokinase and Organism(s) Caenorhabditis elegans and UniProt Accession P30636

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EC Tree
     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.6 Diphosphotransferases
                2.7.6.2 thiamine diphosphokinase
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This record set is specific for:
Caenorhabditis elegans
UNIPROT: P30636 not found.
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Word Map
The taxonomic range for the selected organisms is: Caenorhabditis elegans
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
thiamine pyrophosphokinase, pyrophosphokinase, htpk1, thiamin pyrophosphotransferase, thiamine diphosphokinase, thiaminokinase, thiamin:atp pyrophosphotransferase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
thiamine pyrophosphokinase
encoded by tpk-1
ATP:thiamin pyrophosphotransferase
-
-
-
-
hTPK1
-
-
-
-
pyrophosphokinase, thiamin
-
-
-
-
thiamin kinase
-
-
-
-
thiamin pyrophosphokinase
-
-
-
-
thiamin pyrophosphotransferase
-
-
-
-
thiamin:ATP pyrophosphotransferase
-
-
-
-
thiamine kinase
-
-
-
-
thiaminokinase
-
-
-
-
TPK
-
-
-
-
TPTase
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
diphosphate transfer
-
-
-
-
PATHWAY SOURCE
PATHWAYS
-
-, -, -, -
SYSTEMATIC NAME
IUBMB Comments
ATP:thiamine diphosphotransferase
-
CAS REGISTRY NUMBER
COMMENTARY hide
9026-24-8
-
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
ATP + thiamine
AMP + thiamine diphosphate
show the reaction diagram
the tpk-1 gene functions cell nonautonomously, as the expression of wild-type tpk-1 in one tissue can residue the function of other tissues that express only mutant tpk-1. Thiamine diphosphate can be transported across the cell membrane
-
-
?
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
ATP + thiamine
AMP + thiamine diphosphate
show the reaction diagram
the tpk-1 gene functions cell nonautonomously, as the expression of wild-type tpk-1 in one tissue can residue the function of other tissues that express only mutant tpk-1. Thiamine diphosphate can be transported across the cell membrane
-
-
?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
TPK1_CAEEL
243
0
27314
Swiss-Prot
other Location (Reliability: 3)
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
de Jong, L.; Meng, Y.; Dent, J.; Hekimi, S.
Thiamine pyrophosphate biosynthesis and transport in the nematode Caenorhabditis elegans
Genetics
168
845-854
2004
Caenorhabditis elegans (P30636), Caenorhabditis elegans
Manually annotated by BRENDA team