Reference on EC 2.7.4.8 - guanylate kinase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Hall, S.W.; Khn, H.
Purification and properties of guanylate kinase from bovine retinas and rod outer segments
Eur. J. Biochem.
161
551-556
1986
Bos taurus
Griffith, T.J.; Helleiner, C.W.
The partial purification of deoxynucleoside monophosphate kinases from L cells
Biochim. Biophys. Acta
108
114-124
1965
Mus musculus
Shimono, H.; Sugino, Y.
Metabolism of deoxyribonucleotides. Purification and properties of deoxyguanosine monophosphokinase of calf thymus
Eur. J. Biochem.
19
256-263
1971
Bos taurus, Rattus norvegicus
Buccino, R.J.; Roth, J.S.
Partial purification and properties of ATP:GMP phosphransferase from rat liver
Arch. Biochem. Biophys.
132
49-61
1969
Rattus norvegicus
Oeschger, M.
Guanylate kinase from Escherichia coli B
Methods Enzymol.
51
473-482
1978
Escherichia coli, Escherichia coli B / ATCC 11303
Agarwal, K.C.; Miech, R.P.; Parks, R.E.
Guanylate kinases from human erythrocytes, hog brain, and rat liver
Methods Enzymol.
51
483-490
1978
Homo sapiens, Rattus norvegicus, Sus scrofa
Moriguchi, M.; Kohno, H.; Kamei, M.; Tochikura, T.
Purification and properties of guanylate kinase from bakers yeast
Biochim. Biophys. Acta
662
165-167
1981
Saccharomyces cerevisiae
Berger, A.; Schiltz, E.; Schultz, G.E.
Guanylate kinase from Saccharomyces cerevisiae. Isolation and characterization, crystallization and preliminary X-ray analysis, amino acid sequence and comparison with adenylate kinases
Eur. J. Biochem.
184
433-443
1989
Saccharomyces cerevisiae
Stehle, T.; Schultz, G.E.
Temperature-dependent space-group transitions in crystals of guanylate kinase from yeast
Acta Crystallogr. Sect. B Struct. Sci.
B48
546-548
1992
Saccharomyces cerevisiae
-
Stehle, T.; Schultz, G.E.
Three-dimensional structure of the complex of guanylate kinase from yeast with its substrate GMP
J. Mol. Biol.
211
249-254
1990
Saccharomyces cerevisiae
Le Floc'h, F.; Lafleuriel, J.
Purification and properties of guanylate kinase of mitochondrias from tubers of Jerusalem artichoke
Plant Physiol. Biochem.
28
191-201
1990
Helianthus tuberosus
-
Agarwal, K.C.; Parks, R.E.
Inhibition of rat hepatic guanylate kinase by 6-thioguanosine-5-phosphate and 6-selenoguanosine-5-phosphate
Biochem. Pharmacol.
24
791-795
1975
Rattus norvegicus
Stehle, T.; Schultz, G.E.
Refined structure of the complex between guanylate kinase and its substrate GMP at 2.0 A resolution
J. Mol. Biol.
224
1127-1141
1992
Saccharomyces cerevisiae
Nav, J.F.; Eschbach, A.; Halazy, S.
9-(Phosphonoalkyl)guanine derivatives as substrates or inhibitors of guanylate kinase
Arch. Biochem. Biophys.
295
253-257
1992
Sus scrofa
Boehme, R.E.
Phosphorylation of the antiviral precursor 9-(1,3-dihydroxy-2-propoxymethyl)guanine monophosphate by guanylate kinase isozymes
J. Biol. Chem.
259
12346-12349
1984
Homo sapiens
Hiraga, S.; Sugino, Y.
Nucleoside monophosphokinases of Escherichia coli infected and uninfected with an RNA phage
Biochim. Biophys. Acta
114
416-418
1966
Escherichia coli, Escherichia coli JE24F+
Brady, W.A.; Kokoris, M.S.; Fitzgibbon, M.; Black, M.E.
Cloning, characterization, and modeling of mouse and human guanylate kinases
J. Biol. Chem.
271
16734-16740
1996
Homo sapiens, Mus musculus (Q64520), Mus musculus
Li, Y.; Zhang, Y.; Yan, H.
Kinetic and thermodynamic characterizations of yeast guanylate kinase
J. Biol. Chem.
271
28038-28044
1996
Saccharomyces cerevisiae
Zhang, Y.; Li, Y.; Wu, Y.; Yan, H.
Structural and functional roles of tyrosine 78 of yeast guanylate kinase
J. Biol. Chem.
272
19343-19350
1997
Saccharomyces cerevisiae
Prinz, H.; Lavie, A.; Scheidig, A.J.; Spangenberg, O.; Konrad, M.
Binding of nucleotides to guanylate kinase, p21(ras), and nucleoside-diphosphate kinase studied by nano-electrospray mass spectrometry
J. Biol. Chem.
274
35337-35342
1999
Homo sapiens (Q16774)
Miller, W.H.; Beauchamp, L.M.; Meade, E.; Reardon, J.E.; Biron, K.K.; Smith, A.A.; Goss, C.A.; Miller, R.L.
Phosphorylation of ganciclovir phosphonate by cellular GMP kinase determines the stereoselectivity of anti-human cytomegalovirus activity
Nucleosides Nucleotides Nucleic Acids
19
341-356
2000
Homo sapiens, Sus scrofa
Blaszczyk, J.; Li, Y.; Yan, H.; Ji, X.
Crystal structure of unligated guanylate kinase from yeast reveals GMP-induced conformational changes
J. Mol. Biol.
307
247-257
2001
Saccharomyces cerevisiae (P15454), Saccharomyces cerevisiae
Stolworthy, T.S.; Black, M.E.
The mouse guanylate kinase double mutant E72Q/D103N is a functional adenylate kinase
Protein Eng.
14
903-909
2001
Mus musculus
Sekulic, N.; Shuvalova, L.; Spangenberg, O.; Konrad, M.; Lavie, A.
Structural characterization of the closed conformation of mouse guanylate kinase
J. Biol. Chem.
277
30236-30243
2002
Mus musculus
Stolworthy, T.S.; Krabbenhoft, E.; Black, M.E.
A novel Escherichia coli strain allows functional analysis of guanylate kinase drug resistance and sensitivity
Anal. Biochem.
322
40-47
2003
Escherichia coli, Escherichia coli TS202A
Olsen, O.; Bredt, D.S.
Functional analysis of the nucleotide binding domain of membrane-associated guanylate kinases
J. Biol. Chem.
278
6873-6878
2003
Saccharomyces cerevisiae, Rattus norvegicus
Hible, G.; Renault, L.; Schaeffer, F.; Christova, P.; Zoe Radulescu, A.; Evrin, C.; Gilles, A.M.; Cherfils, J.
Calorimetric and crystallographic analysis of the oligomeric structure of Escherichia coli GMP kinase
J. Mol. Biol.
352
1044-1059
2005
Escherichia coli (P60546), Escherichia coli
El Omari, K.; Dhaliwal, B.; Lockyer, M.; Charles, I.; Hawkins, A.R.; Stammers, D.K.
Structure of Staphylococcus aureus guanylate monophosphate kinase
Acta Crystallogr. Sect. F
F62
949-953
2006
Staphylococcus aureus
Hible, G.; Daalova, P.; Gilles, A.M.; Cherfils, J.
Crystal structures of GMP kinase in complex with ganciclovir monophosphate and Ap5G
Biochimie
88
1157-1164
2006
Escherichia coli (P60546), Escherichia coli
Choi, B.; Zocchi, G.
Guanylate kinase, induced fit, and the allosteric spring probe
Biophys. J.
92
1651-1658
2007
Mycobacterium tuberculosis, Mycobacterium tuberculosis (P9WKE9), Mycobacterium tuberculosis H37Rv (P9WKE9)
Willmon, C.L.; Krabbenhoft, E.; Black, M.E.
A guanylate kinase/HSV-1 thymidine kinase fusion protein enhances prodrug-mediated cell killing
Gene Ther.
13
1309-1312
2006
Homo sapiens, Mus musculus
Sumita, K.; Sato, Y.; Iida, J.; Kawata, A.; Hamano, M.; Hirabayashi, S.; Ohno, K.; Peles, E.; Hata, Y.
Synaptic scaffolding molecule (S-SCAM) membrane-associated guanylate kinase with inverted organization (MAGI)-2 is associated with cell adhesion molecules at inhibitory synapses in rat hippocampal neurons
J. Neurochem.
100
154-166
2007
Rattus norvegicus
Abergel, C.; Blanc, G.; Monchois, V.; Renesto, P.; Sigoillot, C.; Ogata, H.; Raoult, D.; Claverie, J.M.
Impact of the excision of an ancient repeat insertion on Rickettsia conorii guanylate kinase activity
Mol. Biol. Evol.
23
2112-2122
2006
Rickettsia conorii (Q92GC9), Rickettsia conorii
Reese, M.L.; Dakoji, S.; Bredt, D.S.; Doetsch, V.
The guanylate kinase domain of the MAGUK PSD-95 binds dynamically to a conserved motif in MAP1a
Nat. Struct. Mol. Biol.
14
155-163
2007
Rattus norvegicus
Kandeel, M.; Nakanishi, M.; Ando, T.; El-Shazly, K.; Yosef, T.; Ueno, Y.; Kitade, Y.
Molecular cloning, expression, characterization and mutation of Plasmodium falciparum guanylate kinase
Mol. Biochem. Parasitol.
159
130-133
2008
Plasmodium falciparum
Gardoni, F.; Marcello, E.; Di Luca, M.
Postsynaptic density-membrane associated guanylate kinase proteins (PSD-MAGUKs) and their role in CNS disorders
Neuroscience
158
324-333
2008
Homo sapiens, Mus musculus, Rattus norvegicus
Sugimoto, H.; Kusumi, K.; Noguchi, K.; Yano, M.; Yoshimura, A.; Iba, K.
The rice nuclear gene, VIRESCENT 2, is essential for chloroplast development and encodes a novel type of guanylate kinase targeted to plastids and mitochondria
Plant J.
52
512-527
2007
Oryza sativa
Gonzalez-Gutierrez, G.; Miranda-Laferte, E.; Nothmann, D.; Schmidt, S.; Neely, A.; Hidalgo, P.
The guanylate kinase domain of the beta-subunit of voltage-gated calcium channels suffices to modulate gating
Proc. Natl. Acad. Sci. USA
105
14198-14203
2008
Rattus norvegicus, Rattus norvegicus (Q8VGC3)
Mertlikova-Kaiserova, H.; Rumlova, M.; Tloustova, E.; Prochazkova, E.; Holy, A.; Votruba, I.
Point mutations in human guanylate kinase account for acquired resistance to anticancer nucleotide analogue PMEG
Biochem. Pharmacol.
82
131-138
2011
Homo sapiens
Zhu, J.; Shang, Y.; Xia, C.; Wang, W.; Wen, W.; Zhang, M.
Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-binding modules
EMBO J.
30
4986-4997
2011
Homo sapiens, Rattus norvegicus (Q62696)
Kandeel, M.; Kitade, Y.
Binding dynamics and energetic insight into the molecular forces driving nucleotide binding by guanylate kinase
J. Mol. Recognit.
24
322-332
2011
Plasmodium falciparum
Dembowski, J.A.; An, P.; Scoulos-Hanson, M.; Yeo, G.; Han, J.; Fu, X.D.; Grabowski, P.J.
Alternative splicing of a novel inducible exon diversifies the CASK guanylate kinase domain
J. Nucleic Acids
2012
816237
2012
Homo sapiens (O14936)
Mori, S.; Tezuka, Y.; Arakawa, A.; Handa, N.; Shirouzu, M.; Akiyama, T.; Yokoyama, S.
Crystal structure of the guanylate kinase domain from discs large homolog 1 (DLG1/SAP97)
Biochem. Biophys. Res. Commun.
435
334-338
2013
Homo sapiens (Q12959), Homo sapiens
Jain, R.; Khan, N.; Menzel, A.; Rajkovic, I.; Konrad, M.; Techert, S.
Insights into open/closed conformations of the catalytically active human guanylate kinase as investigated by small-angle X-ray scattering
Eur. Biophys. J.
45
81-89
2016
Homo sapiens (Q16774), Homo sapiens
Nomura, Y.; Izumi, A.; Fukunaga, Y.; Kusumi, K.; Iba, K.; Watanabe, S.; Nakahira, Y.; Weber, A.P.; Nozawa, A.; Tozawa, Y.
Diversity in guanosine 3,5-bisdiphosphate (ppGpp) sensitivity among guanylate kinases of bacteria and plants
J. Biol. Chem.
289
15631-15641
2014
Bacillus subtilis, Escherichia coli, Synechococcus elongatus, Saccharomyces cerevisiae (P15454), Saccharomyces cerevisiae, Oryza sativa Japonica Group (Q10M74), Oryza sativa Japonica Group (Q2QPW1), Arabidopsis thaliana (Q94JM2), Pisum sativum (W8VNI6), Pisum sativum (W8VZ39), Pisum sativum, Oryza sativa Japonica Group Nipponbare (Q10M74), Oryza sativa Japonica Group Nipponbare (Q2QPW1), Synechococcus elongatus PCC 7942
Gupta, S.; Yadav, S.; Singh, N.; Verma, A.; Siddiqi, I.; Saxena, J.K.
Purification and characterization of guanylate kinase, a nucleoside monophosphate kinase of Brugia malayi
Parasitology
141
1341-1352
2014
Brugia malayi (Q5GS56), Brugia malayi
Zhang, Y.; Niu, H.; Li, Y.; Chu, H.; Shen, H.; Zhang, D.; Li, G.
Mechanistic insight into the functional transition of the enzyme guanylate kinase induced by a single mutation
Sci. Rep.
5
8405
2015
Saccharomyces cerevisiae (P15454)
Adams, M.; Holden, J.; Menon, A.; Schut, G.; Grunden, A.; Hou, C.; Hutchins, A.; Jenney F.E., J.; Kim, C.; Ma, K.; Pan, G.; Roy, R.; Sapra, R.; Story, S.; Verhagen, M.
Key role for sulfur in peptide metabolism and in regulation of three hydrogenases in the hyperthermophilic archaeon Pyrococcus furiosus
J. Bacteriol.
183
716-724
2001
Pyrococcus furiosus
Cai, X.; Zhang, X.; Li, X.; Liu, M.; Liu, X.; Wang, X.; Zhang, H.; Zheng, X.; Zhang, Z.
The atypical guanylate kinase MoGuk2 plays important roles in asexual/sexual development, conidial septation, and pathogenicity in the rice blast fungus
Front. Microbiol.
8
2467
2017
Pyricularia oryzae
Ansari, M.; Ahsan, M.; Yasmin, S.; Sahoo, G.; Saini, V.; Das, P.
In silico identification of novel antagonists and binding insights by structural and functional analyses of guanylate kinase of Leishmania donovani and interaction with inhibitors
Gene Rep.
8
134-143
2017
Leishmania donovani
-
Gupta, S.; Yadav, S.; Suryanarayanan, V.; Singh, S.K.; Saxena, J.K.
Investigating the folding pathway and substrate induced conformational changes in B. malayi Guanylate kinase
Int. J. Biol. Macromol.
94
621-633
2017
Brugia malayi
Khan, N.; Shah, P.P.; Ban, D.; Trigo-Mourino, P.; Carneiro, M.G.; DeLeeuw, L.; Dean, W.L.; Trent, J.O.; Beverly, L.J.; Konrad, M.; Lee, D.; Sabo, T.M.
Solution structure and functional investigation of human guanylate kinase reveals allosteric networking and a crucial role for the enzyme in cancer
J. Biol. Chem.
294
11920-11933
2019
Homo sapiens (Q16774), Homo sapiens
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