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The taxonomic range for the selected organisms is: Staphylococcus aureus
The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota
Synonyms
thid2, phosphomethylpyrimidine kinase,
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hydroxymethylpyrimidine phosphokinase
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kinase, phosphomethylpyrimidine (phosphorylating)
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phosphomethylpyrimidine kinase
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phospho group transfer
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ATP:4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine phosphotransferase
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(6R)-6-[(2E)-4-oxo-6-phenylhex-2-en-1-yl]-5,6-dihydro-2H-pyran-2-one
lactone isolated from Cryptocarya rugulosa, covalent inhibition
(6R)-6-[(2E)-6-(4-ethynylphenyl)-4-oxohex-2-en-1-yl]-5,6-dihydro-2H-pyran-2-one
derivative of a lactone isolated from Cryptocarya rugulosa, covalent inhibition
(6S)-6-[(2E)-6-(4-ethynylphenyl)-4-oxohex-2-en-1-yl]tetrahydro-2H-pyran-2-one
derivative of a lactone isolated from Cryptocarya rugulosa, covalent inhibition
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0.025
(6R)-6-[(2E)-4-oxo-6-phenylhex-2-en-1-yl]-5,6-dihydro-2H-pyran-2-one
Staphylococcus aureus
pH not specified in the publication, temperature not specified in the publication
0.014
(6R)-6-[(2E)-6-(4-ethynylphenyl)-4-oxohex-2-en-1-yl]-5,6-dihydro-2H-pyran-2-one
Staphylococcus aureus
pH not specified in the publication, temperature not specified in the publication
0.032
(6S)-6-[(2E)-6-(4-ethynylphenyl)-4-oxohex-2-en-1-yl]tetrahydro-2H-pyran-2-one
Staphylococcus aureus
pH not specified in the publication, temperature not specified in the publication
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bifunctional hydroxymethylpyrimidine/phosphomethylpyrimidine kinase
UniProt
brenda
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Nodwell, M.B.; Menz, H.; Kirsch, S.F.; Sieber, S.A.
Rugulactone and its analogues exert antibacterial effects through multiple mechanisms including inhibition of thiamine biosynthesis
ChemBioChem
13
1439-1446
2012
Staphylococcus aureus (P66915)
brenda
2.7.4.7 phosphooxymethylpyrimidine kinase
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