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Information on EC 2.7.4.27 - [pyruvate, phosphate dikinase]-phosphate phosphotransferase and Organism(s) Arabidopsis thaliana and UniProt Accession O49562

for references in articles please use BRENDA:EC2.7.4.27
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EC Tree
IUBMB Comments
The enzyme from the plants maize and Arabidopsis is bifunctional and also catalyses the phosphorylation of pyruvate, phosphate dikinase (EC 2.7.9.1), cf. EC 2.7.11.32, [pyruvate, phosphate dikinase] kinase [2-5].
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This record set is specific for:
Arabidopsis thaliana
UNIPROT: O49562
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Word Map
  • 2.7.4.27
  • maize
  • fission
  • adp-dependent
  • pi-dependent
  • dynamin-related
The taxonomic range for the selected organisms is: Arabidopsis thaliana
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Reaction Schemes
[pyruvate, phosphate dikinase] phosphate
+
=
[pyruvate, phosphate dikinase]
+
Synonyms
pdrp1, atrp1, ppdk regulatory protein, pdrp2, c4 chloroplast ppdk, pyruvate,pi dikinase regulatory protein, pyruvate orthophosphate dikinase regulatory protein, bifunctional regulatory protein of pyruvate,orthophosphate dikinase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
pyruvate, orthophosphate dikinase regulatory protein 1
bifunctional protein kinase/protein phosphatase
PDRP1
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
[pyruvate, phosphate dikinase] phosphate:phosphate phosphotransferase
The enzyme from the plants maize and Arabidopsis is bifunctional and also catalyses the phosphorylation of pyruvate, phosphate dikinase (EC 2.7.9.1), cf. EC 2.7.11.32, [pyruvate, phosphate dikinase] kinase [2-5].
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
[pyruvate, phosphate dikinase] phosphate + phosphate
pyruvate, phosphate dikinase + diphosphate
show the reaction diagram
His458 and Thr456 phosphorylated (inactive), strict requirement for the threonyl phosphate, unable to dephosphorylate Ser-P at this same position
His458 phosphorylated (active)
-
?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
additional information
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
PDRP1_ARATH
403
0
43684
Swiss-Prot
Chloroplast (Reliability: 2)
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
immobilized metal ion affinity chromatography (Ni2+)
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
His-tagged and GFP-fusion proteins expressed in Escherichia coli BL21(DE3)
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Chastain, C.J.; Xu, W.; Parsley, K.; Sarath, G.; Hibberd, J.M.; Chollet, R.
The pyruvate, orthophosphate dikinase regulatory proteins of Arabidopsis possess a novel, unprecedented Ser/Thr protein kinase primary structure
Plant J.
53
854-863
2008
Arabidopsis thaliana (O49562), Arabidopsis thaliana
Manually annotated by BRENDA team