Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Reference on EC 2.7.4.14 - UMP/CMP kinase

Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Neale, G.A.M.; Mitchell, A.; Finch, L.R.
Enzymes of pyrimidine deoxyribonucleotide metabolism in Mycoplasma mycoides subsp. mycoides
J. Bacteriol.
156
1001-1005
1983
Mycoplasma mycoides
Manually annotated by BRENDA team
Ruffner, B.W.; Anderson, E.P.
Adenosine triphosphate: uridine monophosphate-cytidine monophosphate phosphotransferase from Tetrahymena pyriformis
J. Biol. Chem.
244
5994-6002
1969
Tetrahymena pyriformis
Manually annotated by BRENDA team
Hurwitz, J.
The enzymatic incorporation of ribonucleotides into polydeoxynucleotide material
J. Biol. Chem.
234
2351-2358
1959
Escherichia coli, Escherichia coli B / ATCC 11303
Manually annotated by BRENDA team
Orengo, A.; Maness, P.
Pyrimidine nucleoside monophosphate kinase from rat liver and rat Novikoff ascites hepatoma (EC 2.7.4.14)
Methods Enzymol.
51
321-331
1978
Rattus norvegicus
Manually annotated by BRENDA team
Anderson, E.P.
UMP-CMP kinase from Tetrahymena pyriformis
Methods Enzymol.
51
331-337
1978
Tetrahymena pyriformis
Manually annotated by BRENDA team
Scott, E.M.; Wright, R.C.
Kinetics and equilibria of pyrimidine nucleoside monophosphate kinase from human erythrocytes
Biochim. Biophys. Acta
571
45-54
1979
Homo sapiens
Manually annotated by BRENDA team
Maness, P.; Orengo, A.
Activation of rat liver pyrimidine nucleoside monophosphate kinase
Biochim. Biophys. Acta
429
182-190
1976
Rattus norvegicus
Manually annotated by BRENDA team
Maness, P.; Orengo, A.
A pyrimidine nucleoside monophosphate kinase from rat liver
Biochemistry
14
1484-1489
1975
Rattus norvegicus
Manually annotated by BRENDA team
Kobayashi, S.; Kanayama, K.
NADPH activation of deoxycytidylate kinase in rat liver extract: involvement of an endogenous disulfide reductase system
Biochem. Biophys. Res. Commun.
74
1249-1255
1977
Rattus norvegicus
Manually annotated by BRENDA team
Teng, Y.S.; Chen, S.H.; Scott, C.R.
Human erythrocyte pyrimidine nucleoside monophosphate kinase. Partial purification and properties of two allelic gene products
J. Biol. Chem.
251
4179-4183
1976
Homo sapiens
Manually annotated by BRENDA team
Seagrave, J.; Reyes, P.
Pyrimidine nucleoside monophosphate kinase from rat bone marrow cells: chromatographic, electrophoretic, and sedimentation behavior of active and inactive enzyme forms
Arch. Biochem. Biophys.
247
76-83
1986
Rattus norvegicus
Manually annotated by BRENDA team
Gravey, T.Q.; Millar, F.K.; Anderson, E.P.
ATP:UMP-CMP phosphotransferase from Tetrahymena pyriformis. II. Kinetic studies and reaction mechanism with UMP
Biochim. Biophys. Acta
302
38-49
1973
Tetrahymena pyriformis
Manually annotated by BRENDA team
Kohno, H.; Kumagai, H.; Tochikura, T.
Purification and properties of pyrimidine nucleoside monophosphate kinase from bakers yeast
Agric. Biol. Chem.
47
19-24
1983
Saccharomyces cerevisiae
-
Manually annotated by BRENDA team
Seagrave, J.; Reyes, P.
Pyrimidine nucleoside monophosphate kinase from rat bone marrow cells: a kinetic analysis of the reaction mechanism
Arch. Biochem. Biophys.
254
518-525
1987
Rattus norvegicus
Manually annotated by BRENDA team
Hutter, M.C.; Helms, V.
Phosphoryl transfer by a concerted reaction mechanism in UMP/CMP-kinase
Protein Sci.
9
2225-2231
2000
Dictyostelium discoideum
Manually annotated by BRENDA team
Zhou, L.; Lacroute, F.; Thornburg, R.
Cloning, expression in Escherichia coli, and characterization of Arabidopsis thaliana UMP/CMP kinase
Plant Physiol.
117
245-254
1998
Arabidopsis thaliana (O04905), Arabidopsis thaliana
Manually annotated by BRENDA team
Curbo, S.; Amiri, M.; Foroogh, F.; Johansson, M.; Karlsson, A.
The Drosophila melanogaster UMP-CMP kinase cDNA encodes an N-terminal mitochondrial import signal
Biochem. Biophys. Res. Commun.
311
440-445
2003
Drosophila melanogaster
Manually annotated by BRENDA team
Van Rompay, A.R.; Johansson, M.; Karlsson, A.
Phosphorylation of deoxycytidine analog monophosphates by UMP-CMP kinase: molecular characterization of the human enzyme
Mol. Pharmacol.
56
562-569
1999
Homo sapiens (P30085), Homo sapiens
Manually annotated by BRENDA team
Okajima, T.; Fukamizo, T.; Goto, S.; Fukui, T.; Tanizawa, K.
Exchange of nucleoside monophosphate-binding domains in adenylate kinase and UMP/CMP kinase
J. Biochem.
124
359-367
1998
Sus scrofa
Manually annotated by BRENDA team
Zhou, L.; Thornburg, R.
Site-specific mutations of conserved residues in the phosphate-binding loop of the Arabidopsis UMP/CMP kinase alter ATP and UMP binding
Arch. Biochem. Biophys.
358
297-302
1998
Arabidopsis thaliana
Manually annotated by BRENDA team
Pearman, A.T.; Castro-Faria-Neto, H.C.; McIntyre, T.M.; Prescott, S.M.; Stafforini, D.M.
Characterization of human UMP-CMP kinase enzymatic activity and 5' untranslated region
Life Sci.
69
2361-2370
2001
Homo sapiens
Manually annotated by BRENDA team
Liou, J.Y.; Dutschman, G.E.; Lam, W.; Jiang, Z.; Cheng, Y.C.
Characterization of human UMP/CMP kinase and its phosphorylation of D- and L-form deoxycytidine analogue monophosphates
Cancer Res.
62
1624-1631
2002
Homo sapiens
Manually annotated by BRENDA team
Pasti, C.; Gallois-Montbrun, S.; Munier-Lehmann, H.; Veron, M.; Gilles, A.M.; Deville-Bonne, D.
Reaction of human UMP-CMP kinase with natural and analog substrates
Eur. J. Biochem.
270
1784-1790
2003
Dictyostelium sp., Homo sapiens
Manually annotated by BRENDA team
Hewitt, M.M.; Carr, J.M.; Williamson, C.L.; Slocum, R.D.
Effects of phosphate limitation on expression of genes involved in pyrimidine synthesis and salvaging in Arabidopsis
Plant Physiol. Biochem.
43
91-99
2005
Arabidopsis thaliana
Manually annotated by BRENDA team
Topalis, D.; Kumamoto, H.; Amaya Velasco, M.F.; Dugue, L.; Haouz, A.; Alexandre, J.A.; Gallois-Montbrun, S.; Alzari, P.M.; Pochet, S.; Agrofoglio, L.A.; Deville-Bonne, D.
Nucleotide binding to human UMP-CMP kinase using fluorescent derivatives - a screening based on affinity for the UMP-CMP binding site
FEBS J.
274
3704-3714
2007
Homo sapiens (P30085), Homo sapiens
Manually annotated by BRENDA team
Alexandre, J.A.; Roy, B.; Topalis, D.; Pochet, S.; Perigaud, C.; Deville-Bonne, D.
Enantioselectivity of human AMP, dTMP and UMP-CMP kinases
Nucleic Acids Res.
35
4895-4904
2007
Homo sapiens (P30085), Homo sapiens
Manually annotated by BRENDA team
Kocabas, N.A.; Aksoy, P.; Pelleymounter, L.L.; Moon, I.; Ryu, J.S.; Gilbert, J.A.; Salavaggione, O.E.; Eckloff, B.W.; Wieben, E.D.; Yee, V.; Weinshilboum, R.M.; Ames, M.M.
Gemcitabine pharmacogenomics: deoxycytidine kinase and cytidylate kinase gene resequencing and functional genomics
Drug Metab. Dispos.
36
1951-1959
2008
Homo sapiens (P30085)
Manually annotated by BRENDA team
Xu, Y.; Johansson, M.; Karlsson, A.
Human UMP-CMP kinase 2, a novel nucleoside monophosphate kinase localized in mitochondria
J. Biol. Chem.
283
1563-1571
2008
Homo sapiens (Q5EBM0), Homo sapiens
Manually annotated by BRENDA team
Lorenz, T.; Reinstein, J.
The influence of proline isomerization and off-pathway intermediates on the folding mechanism of eukaryotic UMP/CMP kinase
J. Mol. Biol.
381
443-455
2008
Dictyostelium discoideum (P20425), Dictyostelium discoideum
Manually annotated by BRENDA team
Topalis, D.; Kumamoto, H.; Alexandre, J.A.; Dugue, L.; Pochet, S.; Berteina-Raboin, S.; Agrofoglio, L.A.; Deville-Bonne, D.
Looking for new pyrimidine acyclic nucleotide analogues designed for phosphorylation by human UMP-CMP kinase
Nucleosides Nucleotides Nucleic Acids
26
1369-1373
2007
Homo sapiens (P30085), Homo sapiens
Manually annotated by BRENDA team
Alexandre, J.A.; Roy, B.; Topalis, D.; Perigaud, C.; Deville-Bonne, D.
Enantio-selectivity of human nucleoside monophosphate kinases
Nucleosides Nucleotides Nucleic Acids
26
1375-1379
2007
Homo sapiens
Manually annotated by BRENDA team
Liou, J.Y.; Lai, H.R.; Hsu, C.H.; Chang, W.L.; Hsieh, M.J.; Huang, Y.C.; Cheng, Y.C.
Modulation of human UMP/CMP kinase affects activation and cellular sensitivity of deoxycytidine analogs
Biochem. Pharmacol.
79
381-388
2010
Homo sapiens
Manually annotated by BRENDA team
Tsao, N.; Lee, M.H.; Zhang, W.; Cheng, Y.C.; Chang, Z.F.
The contribution of CMP kinase to the efficiency of DNA repair
Cell Cycle
14
354-363
2015
Homo sapiens (P30085)
Manually annotated by BRENDA team
Topalis, D.; Nogueira, T.C.; De Schutter, T.; El Amri, C.; Krecmerova, M.; Naesens, L.; Balzarini, J.; Andrei, G.; Snoeck, R.
Resistance to the nucleotide analogue cidofovir in HPV(+) cells: a multifactorial process involving UMP/CMP kinase 1
Oncotarget
7
10386-10401
2016
Homo sapiens (P30085)
Manually annotated by BRENDA team
Liu, N.Q.; De Marchi, T.; Timmermans, A.; Trapman-Jansen, A.M.; Foekens, R.; Look, M.P.; Smid, M.; van Deurzen, C.H.; Span, P.N.; Sweep, F.C.; Brask, J.B.; Timmermans-Wielenga, V.; Foekens, J.A.; Martens, J.W.; Umar, A.
Prognostic significance of nuclear expression of UMP-CMP kinase in triple negative breast cancer patients
Sci. Rep.
6
32027
2016
Homo sapiens (P30085), Homo sapiens
Manually annotated by BRENDA team
Kikuchi, M.; Kizaki, K.; Shigeno, S.; Toji, N.; Ishiguro-Oonuma, T.; Koshi, K.; Takahashi, T.; Hashizume, K.
Newly identified interferon tau-responsive Hes family BHLH transcription factor 4 and cytidine/uridine monophosphate kinase 2 genes in peripheral blood granulocytes during early pregnancy in cows
Domest. Anim. Endocrinol.
68
64-72
2019
Bos taurus
Manually annotated by BRENDA team
Zhang, X.; Zhang, K.; Zhang, Y.
Pigment epithelium-derived factor facilitates NLRP3 inflammasome activation through downregulating cytidine monophosphate kinase 2 A potential treatment strategy for missed abortion
Int. J. Mol. Med.
45
1436-1446
2020
Homo sapiens (Q5EBM0), Homo sapiens
Manually annotated by BRENDA team
Chen, S.; Wang, X.; Ye, X.; Ma, D.; Chen, C.; Cai, J.; Fu, Y.; Cheng, X.; Chen, Y.; Gong, X.; Jin, J.
Identification of human UMP/CMP kinase 1 as doxorubicin binding target using protein microarray
SLAS Discov.
22
1007-1015
2017
Homo sapiens (P30085), Homo sapiens
Manually annotated by BRENDA team