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Information on EC 2.7.11.22 - cyclin-dependent kinase and Organism(s) Candida albicans and UniProt Accession P43063

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IUBMB Comments
Activation of cyclin-dependent kinases requires association of the enzyme with a regulatory subunit referred to as a cyclin. It is the sequential activation and inactivation of cyclin-dependent kinases, through the periodic synthesis and destruction of cyclins, that provides the primary means of cell-cycle regulation.
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This record set is specific for:
Candida albicans
UNIPROT: P43063
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The taxonomic range for the selected organisms is: Candida albicans
The enzyme appears in selected viruses and cellular organisms
Reaction Schemes
+
a [protein]-(L-serine/L-threonine)
=
+
a [protein]-(L-serine/L-threonine) phosphate
Synonyms
cyclin-dependent kinase, cdk, p34cdc2, cdkl5, cdc2 kinase, cyclin-dependent kinase 5, cyclin-dependent kinase 2, cdc28, cyclin-dependent kinase 4, cyclin-dependent kinase 1, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
cell division control protein 28
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Cyclin-dependent kinase pef1
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-
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PHO85 homolog
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-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
phospho group transfer
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-
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SYSTEMATIC NAME
IUBMB Comments
ATP:cyclin phosphotransferase
Activation of cyclin-dependent kinases requires association of the enzyme with a regulatory subunit referred to as a cyclin. It is the sequential activation and inactivation of cyclin-dependent kinases, through the periodic synthesis and destruction of cyclins, that provides the primary means of cell-cycle regulation.
CAS REGISTRY NUMBER
COMMENTARY hide
150428-23-2
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
58320
x * 58320, calculation from nucleotide sequence
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
?
x * 58320, calculation from nucleotide sequence
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Damagnez, V.; Cottarel, G.
Candida albicans CDK1 and CYB1: cDNA homologues of the cdc2/CDC28 and cdc13/CLB1/CLB2 cell cycle control genes
Gene
172
137-141
1996
Candida albicans (P43063), Candida albicans
Manually annotated by BRENDA team
Sherlock, G.; Bahman, A.M.; Mahal, A.; Shieh, J.C.; Ferreira, M.; Rosamond, J.
Molecular cloning and analysis of CDC28 and cyclin homologues from the human fungal pathogen Candida albicans
Mol. Gen. Genet.
245
716-723
1994
Candida albicans (P43063), Candida albicans
Manually annotated by BRENDA team
Navarro-Garcia, F.; Sanchez, M.; Pla, J.; Nombela, C.
Functional characterization of the MKC1 gene of Candida albicans, which encodes a mitogen-activated protein kinase homolog related to cell integrity
Mol. Cell. Biol.
15
2197-2206
1995
Candida albicans (P43063)
Manually annotated by BRENDA team