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Information on EC 2.7.11.17 - Ca2+/calmodulin-dependent protein kinase and Organism(s) Saccharomyces cerevisiae and UniProt Accession P22517

for references in articles please use BRENDA:EC2.7.11.17
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EC Tree
IUBMB Comments
Requires calmodulin and Ca2+ for activity. A wide range of proteins can act as acceptor, including vimentin, synapsin, glycogen synthase, myosin light chains and the microtubule-associated tau protein. Not identical with EC 2.7.11.18 (myosin-light-chain kinase) or EC 2.7.11.26 (tau-protein kinase).
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Saccharomyces cerevisiae
UNIPROT: P22517
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Word Map
The taxonomic range for the selected organisms is: Saccharomyces cerevisiae
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Reaction Schemes
+
a [protein]-(L-serine/L-threonine)
=
+
a [protein]-(L-serine/L-threonine) phosphate
Synonyms
caldesmon, cam kinase ii, camkiv, cam kinase, calcium/calmodulin-dependent protein kinase ii, calmodulin-dependent protein kinase, camkk2, calcium/calmodulin-dependent protein kinase, ca2+/calmodulin-dependent protein kinase, camk ii, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
calcium/calmodulin-dependent protein kinase II
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CAKI
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-
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calcium/calmodulin-dependent protein kinase I
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caldesmon
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Calspermin
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CAM kinase-GR
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CMPK
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kinase, caldesmon (phosphorylating)
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-
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kinase, microtubule-associated protein 2 (phosphorylating)
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MAP kinase
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MAP-2 kinase
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MAP-2 protein serine kinase
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microtubule associated protein kinase
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microtubule-associated protein 2 kinase
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peripheral plasma membrane protein CaMGUK
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
phospho group transfer
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SYSTEMATIC NAME
IUBMB Comments
ATP:protein phosphotransferase (Ca2+/calmodulin-dependent)
Requires calmodulin and Ca2+ for activity. A wide range of proteins can act as acceptor, including vimentin, synapsin, glycogen synthase, myosin light chains and the microtubule-associated tau protein. Not identical with EC 2.7.11.18 (myosin-light-chain kinase) or EC 2.7.11.26 (tau-protein kinase).
CAS REGISTRY NUMBER
COMMENTARY hide
141467-21-2
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93229-57-3
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97350-82-8
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METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Ca2+
Ca2+/calmodulin-dependent
Ca2+
Ca2+/calmodulin-dependent
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Ohya, Y.; Kawasaki, H.; Suzuki, K.; Londesborough, J.; Anraku, Y.
Two yeast genes encoding calmodulin-dependent protein kinases. Isolation, sequencing and bacterial expressions of CMK1 and CMK2
J. Biol. Chem.
266
12784-12794
1991
Saccharomyces cerevisiae (P22517), Saccharomyces cerevisiae (P27466), Saccharomyces cerevisiae
Manually annotated by BRENDA team
Pausch, M.H.; Kaim, D.; Kunisawa, R.; Admon, A.; Thorner, J.
Multiple Ca2+/calmodulin-dependent protein kinase genes in a unicellular eukaryote
EMBO J.
10
1511-1522
1991
Saccharomyces cerevisiae (P22517), Saccharomyces cerevisiae (P27466), Saccharomyces cerevisiae
Manually annotated by BRENDA team