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Information on EC 2.7.11.13 - protein kinase C and Organism(s) Schizosaccharomyces pombe and UniProt Accession P36582

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IUBMB Comments
A family of serine- and threonine-specific protein kinases that depend on lipids for activity. They can be activated by calcium but have a requirement for the second messenger diacylglycerol. Members of this group of enzymes phosphorylate a wide variety of protein targets and are known to be involved in diverse cell-signalling pathways. Members of the protein kinase C family also serve as major receptors for phorbol esters, a class of tumour promoters.
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Schizosaccharomyces pombe
UNIPROT: P36582
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Word Map
The taxonomic range for the selected organisms is: Schizosaccharomyces pombe
The enzyme appears in selected viruses and cellular organisms
Reaction Schemes
+
a [protein]-(L-serine/L-threonine)
=
+
a [protein]-(L-serine/L-threonine) phosphate
Synonyms
protein kinase c, pkcalpha, pkc-alpha, pkc alpha, pkcepsilon, pkc-delta, pkczeta, pkc-epsilon, pkc delta, pkc-zeta, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
protein kinase C-like 1
-
Calcium-dependent protein kinase C
-
-
-
-
epsilonPKC
-
-
-
-
PKC
-
-
-
-
protein kinase C
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-
-
-
protein kinase C-like 2
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protein kinase-C
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-
-
-
SYSTEMATIC NAME
IUBMB Comments
ATP:protein phosphotransferase (diacylglycerol-dependent)
A family of serine- and threonine-specific protein kinases that depend on lipids for activity. They can be activated by calcium but have a requirement for the second messenger diacylglycerol. Members of this group of enzymes phosphorylate a wide variety of protein targets and are known to be involved in diverse cell-signalling pathways. Members of the protein kinase C family also serve as major receptors for phorbol esters, a class of tumour promoters.
CAS REGISTRY NUMBER
COMMENTARY hide
141436-78-4
calcium-dependent protein kinase C
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Toda, T.; Shimanuki, M.; Yanagida, M.
Two novel protein kinase C-related genes of fission yeast are essential for cell viability and implicated in cell shape control
EMBO J.
12
1987-1995
1993
Schizosaccharomyces pombe (P36582), Schizosaccharomyces pombe (P36583), Schizosaccharomyces pombe
Manually annotated by BRENDA team
Ding, D.Q.; Tomita, Y.; Yamamoto, A.; Chikashige, Y.; Haraguchi, T.; Hiraoka, Y.
Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library
Genes Cells
5
169-190
2000
Schizosaccharomyces pombe (P36583)
Manually annotated by BRENDA team
Mazzei, G.J.; Schmid, E.M.; Knowles, J.K.; Payton, M.A.; Maundrell, K.G.
A Ca(2+)-independent protein kinase C from fission yeast
J. Biol. Chem.
268
7401-7406
1993
Schizosaccharomyces pombe (P36583), Schizosaccharomyces pombe
Manually annotated by BRENDA team