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Information on EC 2.7.11.1 - non-specific serine/threonine protein kinase and Organism(s) Schizosaccharomyces pombe and UniProt Accession P50527

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IUBMB Comments
This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analysed to date.
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This record set is specific for:
Schizosaccharomyces pombe
UNIPROT: P50527
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Word Map
The taxonomic range for the selected organisms is: Schizosaccharomyces pombe
The enzyme appears in selected viruses and cellular organisms
Reaction Schemes
+
a [protein]-(L-serine/L-threonine)
=
+
a [protein]-(L-serine/L-threonine) phosphate
Synonyms
protein kinase a, 14-3-3, camkii, p-akt, lrrk2, c-jun n-terminal kinase, serine/threonine kinase, raf-1, protein kinase b, gsk-3, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
serine/threonine-protein kinase pak1/shk1
-
A-kinase
-
-
-
-
A-T, mutated
-
-
-
-
A-T, mutated homolog
-
-
-
-
AMH type II receptor
-
-
-
-
Anti-sigma B factor rsbT
-
-
-
-
AP50 kinase
-
-
-
-
Ataxia telangiectasia mutated
-
-
-
-
Ataxia telangiectasia mutated homolog
-
-
-
-
ATP-protein transphosphorylase
-
-
-
-
betaIIPKC
-
-
-
-
Breast-tumor-amplified kinase
-
-
-
-
Calcium-dependent protein kinase C
-
-
-
-
Calcium/phospholipid-dependent protein kinase
-
-
-
-
cAMP-dependent protein kinase A
-
-
-
-
casein kinase
-
-
-
-
casein kinase 1gamma
casein kinase 2
-
-
-
-
casein kinase I
-
-
-
-
casein kinase I homolog cki1
casein kinase I homolog cki3
-
casein kinase I homolog hhp1
-
casein kinase I homolog hhp2
-
casein kinase II
casein kinase-2
-
-
-
-
CDC25 suppressing protein kinase
-
-
-
-
cell cycle protein kinase hsk1
-
cell cycle protein kinase spo4
-
Cell division cycle 2-like
-
-
-
-
checkpoint serine/threonine-protein kinase bub1
-
CK-2
-
-
-
-
CK2
-
-
-
-
CK2-alpha
-
-
-
-
CKI
-
-
-
-
CKII
-
-
-
-
CLP-36 interacting kinase
-
-
-
-
cyclic monophosphate-dependent protein kinase
-
-
-
-
cyclic nucleotide-dependent protein kinase
-
-
-
-
cyclin-dependent kinase
-
-
-
-
cytidine 3',5'-cyclic monophosphate-responsive protein kinase
-
-
-
-
DNA-PKcs
-
-
-
-
DNPK1
-
-
-
-
dSTPK61
-
-
-
-
G11 protein
-
-
-
-
G2-specific protein kinase fin1
-
hARK1
-
-
-
-
histone kinase
-
-
-
-
hPDK1
-
-
-
-
Hpr kinase
-
-
-
-
hPSK
-
-
-
-
HSPK 21
-
-
-
-
HSPK 36
-
-
-
-
hydroxyalkyl-protein kinase
-
-
-
-
Kinase interacting with stathmin
-
-
-
-
kinase, casein (phosphorylating)
-
-
-
-
kinase, protamine (phosphorylating)
-
-
-
-
kinase, protein (phosphorylating)
-
-
-
-
kinase, protein, A (phosphorylating)
-
-
-
-
kinase, protein, C (phosphorylating)
-
-
-
-
Lymphocyte-oriented kinase
-
-
-
-
M phase-specific cdc2 kinase
-
-
-
-
meiosis-specific serine/threonine-protein kinase MEK1
-
mitogen-activated S6 kinase
-
-
-
-
mitosis inducer protein kinase cdr1
-
mitosis inducer protein kinase cdr2
-
mitotic control element nim1+
-
mPDK1
-
-
-
-
MPSK
-
-
-
-
Myristoylated and palmitoylated serine-threonine kinase
-
-
-
-
negative regulator of sexual conjugation and meiosis
-
NY-REN-55 antigen
-
-
-
-
P-CIP2
-
-
-
-
P460
-
-
-
-
p46Eg265
-
-
-
-
p46XlEg22
-
-
-
-
p82 kinase
-
-
-
-
pEg2
-
-
-
-
phosphorylase b kinase kinase
-
-
-
-
Phototropin
-
-
-
-
Pim-2h
-
-
-
-
PKA
-
-
-
-
PkB kinase
-
-
-
-
pp39-mos
-
-
-
-
Pre-mRNA protein kinase
-
-
-
-
protamine kinase
-
-
-
-
protein glutamyl kinase
-
-
-
-
protein kinase (phosphorylating)
-
-
-
-
Protein kinase B kinase
-
-
-
-
protein kinase CK2
-
-
-
-
protein kinase KIN1
-
Protein kinase Krct
-
-
-
-
Protein kinase MST
-
-
-
-
protein kinase p58
-
-
-
-
Protein kinase PKL12
-
-
-
-
protein phosphokinase
-
-
-
-
protein serine kinase
-
-
-
-
protein serine-threonine kinase
-
-
-
-
protein-aspartyl kinase
-
-
-
-
protein-cysteine kinase
-
-
-
-
protein-serine kinase
-
-
-
-
protein-serine/threonine kinase
-
-
-
-
PRP4 kinase
-
-
-
-
PRP4 pre-mRNA processing factor 4 homolog
-
-
-
-
PSK-H1
-
-
-
-
Raf kinase
-
-
-
-
Raf-1
-
-
-
-
ratAurA
-
-
-
-
ribosomal protein S6 kinase II
-
-
-
-
ribosomal S6 protein kinase
-
-
-
-
RP1 protein
-
-
-
-
S-receptor kinase
-
-
-
-
serine kinase
-
-
-
-
serine protein kinase
-
-
-
-
serine(threonine) protein kinase
-
-
-
-
serine-specific protein kinase
-
-
-
-
serine/threonine kinase
-
-
-
-
Serine/threonine kinase 15
-
-
-
-
Serine/threonine kinase Ayk1
-
-
-
-
serine/threonine protein kinase
-
-
-
-
serine/threonine-protein kinase ark1
-
serine/threonine-protein kinase Chk1
-
Serine/threonine-protein kinase NRK2
-
-
-
-
Serine/threonine-protein kinase NYD-SPK
-
-
-
-
serine/threonine-protein kinase orb6
-
serine/threonine-protein kinase prp4
-
serine/threonine-protein kinase sck1
-
serine/threonine-protein kinase shk2
-
serine/threonine-protein kinase ssp1
-
SNF1-like protein kinase
-
SRK
-
-
-
-
Ste20-like kinase
-
-
-
-
STE20-like kinase MST1
-
-
-
-
STE20-like kinase MST2
-
-
-
-
STE20-like kinase MST3
-
-
-
-
Switch protein/serine kinase
-
-
-
-
T-antigen kinase
-
-
-
-
threonine-specific protein kinase
-
-
-
-
Twitchin kinase
-
-
-
-
type-2 casein kinase
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
phospho group transfer
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
ATP:protein phosphotransferase (non-specific)
This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analysed to date.
CAS REGISTRY NUMBER
COMMENTARY hide
191808-15-8
phosphoinositide dependent protein kinase 1
340830-03-7
-
37278-10-7
-
377752-08-4
ribosomal protein S6 kinase 2
389133-24-8
ribosomal S6 kinase 3
52660-18-1
casein kinase, protein kinase CK2
9026-43-1
this CAS Reg. No. encompasses a great variety of protein kinases including the serine/threonine specific kinases
90698-26-3
ribosomal protein S6 kinase 1
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
ATP + protein
ADP + phosphoprotein
show the reaction diagram
Pak1 protein is likely to be an effector for Cdc42p or a related GTPase, Pak1p may be involved in the maintenance of cell polarity and in mating
-
-
?
ATP + a protein
ADP + a phosphoprotein
show the reaction diagram
ATP + histone H3
?
show the reaction diagram
Ark1 phosphorylates Ser10 of histone H3 in vivo
-
-
?
ATP + histone H3
ADP + phosphorylated histone
show the reaction diagram
Ark1 phosphorylates Ser10 of histone H3 in vivo
-
-
?
ATP + myelin basic protein
ADP + phosphorylated myelin basic protein
show the reaction diagram
-
-
-
?
ATP + protein
ADP + phosphoprotein
show the reaction diagram
ATP + SR protein
ADP + ?
show the reaction diagram
ATP + Tea1
ADP + phospho-Tea1
show the reaction diagram
ATP + Tea1 protein
ADP + phosphorylated Tea1 protein
show the reaction diagram
-
-
-
-
?
ATP + topoisomerase II
ADP + phosphorylated topoisomerase II
show the reaction diagram
casein + ATP
phosphorylated casein + ADP
show the reaction diagram
additional information
?
-
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
ATP + protein
ADP + phosphoprotein
show the reaction diagram
Pak1 protein is likely to be an effector for Cdc42p or a related GTPase, Pak1p may be involved in the maintenance of cell polarity and in mating
-
-
?
ATP + a protein
ADP + a phosphoprotein
show the reaction diagram
ATP + histone H3
?
show the reaction diagram
Ark1 phosphorylates Ser10 of histone H3 in vivo
-
-
?
ATP + SR protein
ADP + ?
show the reaction diagram
ATP + Tea1
ADP + phospho-Tea1
show the reaction diagram
-
-
-
?
ATP + Tea1 protein
ADP + phosphorylated Tea1 protein
show the reaction diagram
-
-
-
-
?
ATP + topoisomerase II
ADP + phosphorylated topoisomerase II
show the reaction diagram
-
-
-
?
additional information
?
-
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
mitotic, activation of the checkpoint results in the recruitment of Bub1 to centromeres, Bub1 is recruited to kinetochores during the early stages of mitosis. A pool of Bub1 remains centromere-associated at metaphase and even until telophase
-
Manually annotated by BRENDA team
activation of the checkpoint results in the recruitment of Bub1 to centromeres, Bub1 is recruited to kinetochores during the early stages of mitosis. A pool of Bub1 remains centromere-associated at metaphase and even until telophase
Manually annotated by BRENDA team
throughout G2 Ark1 is concentrated in one to three nuclear foci that are not associated with the spindle pole body/centromere complex. Following commitment to mitosis Ark1 associated with chromatin and is particularly concentrated at several sites including kinetochores/centromeres. Kinetochore/centromere association diminishes during anaphase A, after which it is distributed along the spindle. The protein becomes restricted to a small central zone that transiently enlarges as the spindle extends
Manually annotated by BRENDA team
additional information
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
drug target
possible benefits of applying CKII inhibitors in combination with topo II catalytic inhibitors for effective prevention of mitotic chromosome segregation in tumor cells
evolution
malfunction
cki3DELTA mutant cells become hypersensitive to Calcofluor White, indicating that NETO execution at a proper cell cycle stage is important for the maintenance of cell integrity, although the involvement of Cki3 in cell integrity independent of NETO regulation is also possible. Cells containing a kinase-dead version of Cki3 (Cki3KD) or membrane localization-defective Cki3SS mutant also displays a similar faster mobility of Tea1
metabolism
attenuation of CKII-controlled topoisomerase II phosphorylation along with catalytic topo II inhibition may promote anticancer effects
physiological function
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
52000
x * 52000, calculation from nucleotide sequence
58370
x * 58370, calculation from nucleotide sequence
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
POSTTRANSLATIONAL MODIFICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
phosphoprotein
CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
a mutant cki3 gene in which a highly conserved lysine residue in the kinase subdomain II is substituted to arginine, loses the ability to recover the growth defect in the srs1 mutant, indicating that catalytic activity is necessary for suppression. Gene disruption reveals that cki3+ is dispensable for cell viability, and cells lacking functional cki3+ exhibit no characteristic phenotype
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
catalytic alpha-subunit and beta-subunit
recombinant expression of GFP-tagged enzyme in Cki3DELTA cells
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Boeckmann, B.; Bairoch, A.; Apweiler, R.; Blatter, M.C.; Estreicher, A.; Gasteiger, E.; Martin M.J.; Michoud, K.; O'Donovan, C.; Phan, I.; Pilbout, S.; Schneider, M.
The SWISS-PROT protein knowledgebase and its supplement TrEMBL
Nucleic Acids Res.
31
365-370
2003
Homo sapiens (O15530), Schizosaccharomyces pombe (Q12701)
Manually annotated by BRENDA team
Verde, F.; Wiley, D.J.; Nurse, P.
Fission yeast orb6, a ser/thr protein kinase related to mammalian rho kinase and myotonic dystrophy kinase, is required for maintenance of cell polarity and coordinates cell morphogenesis with the cell cycle
Proc. Natl. Acad. Sci. USA
95
7526-7531
1998
Schizosaccharomyces pombe (O13310), Schizosaccharomyces pombe
Manually annotated by BRENDA team
Jin, M.; Fujita, M.; Culley, B.M.; Apolinario, E.; Yamamoto, M.; Maundrell, K.; Hoffman, C.S.
sck1, a high copy number suppressor of defects in the cAMP-dependent protein kinase pathway in fission yeast, encodes a protein homologous to the Saccharomyces cerevisiae SCH9 kinase
Genetics
140
457-467
1995
Schizosaccharomyces pombe (P50530)
Manually annotated by BRENDA team
Wood, V.; Gwilliam, R.; Rajandream, M.A.; Lyne, M.; Lyne, R.; et al.
The genome sequence of Schizosaccharomyces pombe
Nature
415
871-880
2002
Schizosaccharomyces pombe (O13839), Schizosaccharomyces pombe (O59790), Schizosaccharomyces pombe (O74135), Schizosaccharomyces pombe (O74536), Schizosaccharomyces pombe (O94751), Schizosaccharomyces pombe (P07334), Schizosaccharomyces pombe (P08092), Schizosaccharomyces pombe (P34208), Schizosaccharomyces pombe (P36616), Schizosaccharomyces pombe (P38938), Schizosaccharomyces pombe (P40231), Schizosaccharomyces pombe (P40233), Schizosaccharomyces pombe (P40234), Schizosaccharomyces pombe (P40235), Schizosaccharomyces pombe (P40236), Schizosaccharomyces pombe (P50526), Schizosaccharomyces pombe (P50527), Schizosaccharomyces pombe (P50582), Schizosaccharomyces pombe (P87050), Schizosaccharomyces pombe (Q07538), Schizosaccharomyces pombe (Q09170), Schizosaccharomyces pombe (Q10056), Schizosaccharomyces pombe (Q10292), Schizosaccharomyces pombe (Q9UQY9)
Manually annotated by BRENDA team
Petersen, J.; Paris, J.; Willer, M.; Philippe, M.; Hagan, I.M.
The S. pombe aurora-related kinase Ark1 associates with mitotic structures in a stage dependent manner and is required for chromosome segregation
J. Cell Sci.
114
4371-4384
2001
Schizosaccharomyces pombe (O59790), Schizosaccharomyces pombe
Manually annotated by BRENDA team
Matsusaka, T.; Hirata, D.; Yanagida, M.; Toda, T.
A novel protein kinase gene ssp1+ is required for alteration of growth polarity and actin localization in fission yeast
EMBO J.
14
3325-3338
1995
Schizosaccharomyces pombe (P50526)
Manually annotated by BRENDA team
Feilotter, H.; Nurse, P.; Young, P.G.
Genetic and molecular analysis of cdr1/nim1 in Schizosaccharomyces pombe
Genetics
127
309-318
1991
Schizosaccharomyces pombe (P07334)
Manually annotated by BRENDA team
Russell, P.; Nurse, P.
The mitotic inducer nim1+ functions in a regulatory network of protein kinase homologs controlling the initiation of mitosis
Cell
49
569-576
1987
Schizosaccharomyces pombe (P07334), Schizosaccharomyces pombe
Manually annotated by BRENDA team
Levin, D.E.; Bishop, J.M.
A putative protein kinase gene (kin1+) is important for growth polarity in Schizosaccharomyces pombe
Proc. Natl. Acad. Sci. USA
87
8272-8276
1990
Schizosaccharomyces pombe (P22987)
Manually annotated by BRENDA team
Osaka, F.; Seino, H.; Seno, T.; Yamao, F.
A ubiquitin-conjugating enzyme in fission yeast that is essential for the onset of anaphase in mitosis
Mol. Cell. Biol.
17
3388-3397
1997
Schizosaccharomyces pombe (P34208)
Manually annotated by BRENDA team
Furnari, B.; Rhind, N.; Russell, P.
Cdc25 mitotic inducer targeted by chk1 DNA damage checkpoint kinase
Science
277
1495-1497
1997
Schizosaccharomyces pombe (P34208)
Manually annotated by BRENDA team
Al-Khodairy, F.; Fotou, E.; Sheldrick, K.S.; Griffiths, D.J.; Lehmann, A.R.; Carr, A.M.
Identification and characterization of new elements involved in checkpoint and feedback controls in fission yeast
Mol. Biol. Cell
5
147-160
1994
Schizosaccharomyces pombe (P34208)
Manually annotated by BRENDA team
Walworth, N.; Davey, S.; Beach, D.
Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2
Nature
363
368-371
1993
Schizosaccharomyces pombe (P34208)
Manually annotated by BRENDA team
Kanoh, J.; Russell, P.
The protein kinase Cdr2, related to Nim1/Cdr1 mitotic inducer, regulates the onset of mitosis in fission yeast
Mol. Biol. Cell
9
3321-3334
1998
Schizosaccharomyces pombe (P87050)
Manually annotated by BRENDA team
Breeding, C.S.; Hudson, J.; Balasubramanian, M.K.; Hemmingsen, S.M.; Young, P.G.; Gould, K.L.
The cdr2(+) gene encodes a regulator of G2/M progression and cytokinesis in Schizosaccharomyces pombe
Mol. Biol. Cell
9
3399-3415
1998
Schizosaccharomyces pombe (P87050), Schizosaccharomyces pombe
Manually annotated by BRENDA team
Murakami, H.; Okayama, H.
A kinase from fission yeast responsible for blocking mitosis in S phase
Nature
374
817-819
1995
Schizosaccharomyces pombe (Q09170)
Manually annotated by BRENDA team
Kitamura, K.; Yamashita, I.
Identification of a novel casein kinase-1 homolog in fission yeast Schizosaccharomyces pombe
Gene
214
131-137
1998
Schizosaccharomyces pombe (O74135)
Manually annotated by BRENDA team
Wang, P.C.; Vancura, A.; Desai, A.; Carmel, G.; Kuret, J.
Cytoplasmic forms of fission yeast casein kinase-1 associate primarily with the particulate fraction of the cell
J. Biol. Chem.
269
12014-12023
1994
Schizosaccharomyces pombe (P40233), Schizosaccharomyces pombe (P40234)
Manually annotated by BRENDA team
Xu, R.M.; Carmel, G.; Sweet, R.M.; Kuret, J.; Cheng, X.
Crystal structure of casein kinase-1, a phosphate-directed protein kinase
EMBO J.
14
1015-1023
1995
Schizosaccharomyces pombe (P40233)
Manually annotated by BRENDA team
Dhillon, N.; Hoekstra, M.F.
Characterization of two protein kinases from Schizosaccharomyces pombe involved in the regulation of DNA repair
EMBO J.
13
2777-2788
1994
Schizosaccharomyces pombe (P40235), Schizosaccharomyces pombe (P40236)
Manually annotated by BRENDA team
Kearney, P.H.; Ebert, M.; Kuret, J.
Molecular cloning and sequence analysis of two novel fission yeast casein kinase-1 isoforms
Biochem. Biophys. Res. Commun.
203
231-236
1994
Schizosaccharomyces pombe (P40235), Schizosaccharomyces pombe (P40236), Schizosaccharomyces pombe
Manually annotated by BRENDA team
Roussou, I.; Draetta, G.
The Schizosaccharomyces pombe casein kinase II alpha and beta subunits: evolutionary conservation and positive role of the beta subunit
Mol. Cell. Biol.
14
576-586
1994
Schizosaccharomyces pombe (P40231), Schizosaccharomyces pombe
Manually annotated by BRENDA team
Snell, V.; Nurse, P.
Genetic analysis of cell morphogenesis in fission yeast--a role for casein kinase II in the establishment of polarized growth
EMBO J.
13
2066-2074
1994
Schizosaccharomyces pombe (P40231), Schizosaccharomyces pombe
Manually annotated by BRENDA team
Marcus, S.; Polverino, A.; Chang, E.; Robbins, D.; Cobb, M.H.; Wigler, M.H.
Shk1, a homolog of the Saccharomyces cerevisiae Ste20 and mammalian p65PAK protein kinases, is a component of a Ras/Cdc42 signaling module in the fission yeast Schizosaccharomyces pombe
Proc. Natl. Acad. Sci. USA
92
6180-6184
1995
Schizosaccharomyces pombe (P50527)
Manually annotated by BRENDA team
Ottilie, S.; Miller, P.J.; Johnson, D.I.; Creasy, C.L.; Sells, M.A.; Bagrodia, S.; Forsburg, S.L.; Chernoff, J.
Fission yeast pak1+ encodes a protein kinase that interacts with Cdc42p and is involved in the control of cell polarity and mating
EMBO J.
14
5908-5919
1995
Schizosaccharomyces pombe (P50527), Schizosaccharomyces pombe
Manually annotated by BRENDA team
Yang, P.; Kansra, S.; Pimental, R.A.; Gilbreth, M.; Marcus, S.
Cloning and characterization of shk2, a gene encoding a novel p21-activated protein kinase from fission yeast
J. Biol. Chem.
273
18481-18489
1998
Schizosaccharomyces pombe (Q10056)
Manually annotated by BRENDA team
Takeuchi, M.; Yanagida, M.
A mitotic role for a novel fission yeast protein kinase dsk1 with cell cycle stage dependent phosphorylation and localization
Mol. Biol. Cell
4
247-260
1993
Schizosaccharomyces pombe (P36616), Schizosaccharomyces pombe
Manually annotated by BRENDA team
Alahari, S.K.; Schmidt, H.; Kaufer, N.F.
The fission yeast prp4+ gene involved in pre-mRNA splicing codes for a predicted serine/threonine kinase and is essential for growth
Nucleic Acids Res.
21
4079-4083
1993
Schizosaccharomyces pombe (Q07538), Schizosaccharomyces pombe
Manually annotated by BRENDA team
Samejima, I.; Yanagida, M.
Identification of cut8+ and cek1+, a novel protein kinase gene, which complement a fission yeast mutation that blocks anaphase
Mol. Cell. Biol.
14
6361-6371
1994
Schizosaccharomyces pombe (P38938)
Manually annotated by BRENDA team
McLeod, M.; Beach, D.
Homology between the ran1+ gene of fission yeast and protein kinases
EMBO J.
5
3665-3671
1986
Schizosaccharomyces pombe (P08092)
Manually annotated by BRENDA team
Bernard, P.; Hardwick, K.; Javerzat, J.P.
Fission yeast bub1 is a mitotic centromere protein essential for the spindle checkpoint and the preservation of correct ploidy through mitosis
J. Cell. Biol.
143
1775-1787
1998
Schizosaccharomyces pombe (O94751)
Manually annotated by BRENDA team
Masai, H.; Miyake, T.; Arai, K.
Hsk1+, a Schizosaccharomyces pombe gene related to Saccharomyces cerevisiae CDC7, is required for chromosomal replication
EMBO J.
14
3094-3104
1995
Schizosaccharomyces pombe (P50582), Schizosaccharomyces pombe
Manually annotated by BRENDA team
Nakamura, T.; Nakamura-Kubo, M.; Shimoda, C.
Novel fission yeast Cdc7-Dbf4-like kinase complex required for the initiation and progression of meiotic second division
Mol. Cell. Biol.
22
309-320
2002
Schizosaccharomyces pombe (Q9UQY9), Schizosaccharomyces pombe
Manually annotated by BRENDA team
Koyano, T.; Barnouin, K.; Snijders, A.; Kume, K.; Hirata, D.; Toda, T.
Casein kinase 1gamma acts as a molecular switch for cell polarization through phosphorylation of the polarity factor Tea1 in fission yeast
Genes Cells
20
1046-1058
2015
Schizosaccharomyces pombe
Manually annotated by BRENDA team
Koyano, T.; Barnouin, K.; Snijders, A.; Kume, K.; Hirata, D.; Toda, T.
Casein kinase 1gamma acts as a molecular switch for cell polarization through phosphorylation of the polarity factor Tea1 in fission yeast
Genes Cells
20
1046-1058
2015
Schizosaccharomyces pombe (O74135), Schizosaccharomyces pombe ATCC 24843 (O74135)
-
Manually annotated by BRENDA team
Nakazawa, N.; Arakawa, O.; Ebe, M.; Yanagida, M.
Casein kinase II-dependent phosphorylation of DNA topoisomerase II suppresses the effect of a catalytic topo II inhibitor, ICRF-193, in fission yeast
J. Biol. Chem.
294
3772-3782
2019
Schizosaccharomyces pombe (P40231), Schizosaccharomyces pombe, Schizosaccharomyces pombe 972 (P40231)
Manually annotated by BRENDA team