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IUBMB CommentsUnlike EC 2.7.10.1, receptor protein-tyrosine kinase, this protein-tyrosine kinase does not have a transmembrane domain. In the human genome, 32 non-specific protein-tyrosine kinases have been identified and these can be divided into ten families .
Synonyms
bcr-abl, focal adhesion kinase, c-abl, zap-70, src kinase, janus kinase, v-src, ephb4, p56lck, bruton's tyrosine kinase,
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tyrosine-protein kinase abl-1
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70 kDa zeta-associated protein
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Agammaglobulinaemia tyrosine kinase
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Amylovoran biosynthesis membrane-associated protein amsA
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B cell progenitor kinase
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B lymphocyte kinase
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B-cell/myeloid kinase
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BCR-ABL tyrosine kinase
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BMP type II receptor
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BMP-2/BMP-4 receptor
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Bone marrow kinase BMX
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Breast tumor kinase
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Bruton's tyrosine kinase
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Calcium-dependent tyrosine kinase
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Cell adhesion kinase beta
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cell-surface receptor daf-1
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cell-surface receptor daf-4
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ectoprotein kinase
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Epithelial and endothelial tyrosine kinase
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EPS I polysaccharide export protein epsB
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focal adhesion kinase 1
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gene lck protein kinase
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gene lck tyrosine kinase
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Hematopoietic consensus tyrosine-lacking kinase
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Hemopoietic cell kinase
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IL-2-inducible T-cell kinase
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JAK protein tyrosine kinase
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kinase, protein (phosphorylating tyrosine)
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kinase, protein p56lck (phosphorylating)
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Lck Tyrosine kinase
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Leukocyte janus kinase
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nonreceptor protein tyrosine kinase
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Nuclear tyrosine protein kinase RAK
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p56lck protein kinase
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p56lck protein tyrosine kinase
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p56lck tyrosine kinase
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phosphotyrosyl-protein kinase
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Protein kinase (tyrosine-phosphorylating)
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Protein kinase BATK
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Protein kinase HYL
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Protein kinase Lck
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Protein kinase NTK
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Protein kinase p56-LCK
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Protein kinase p56lck
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Protein p56c-lck kinase
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Protein p56lck tyrosine kinase
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Protein tyrosine kinase
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protein tyrosine kinase 2beta
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Protein tyrosine kinase lck
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Protein tyrosine kinase p56lck
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Protein tyrosine kinase pp56lck
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Protein-tyrosine kinase C-TKL
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Protein-tyrosine kinase CYL
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Related adhesion focal tyrosine kinase
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Resting lymphocyte kinase
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S-domain receptor-like protein kinase
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serine/threonine-protein kinase sma-6
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Spleen tyrosine kinase
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SRC-related intestinal kinase
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Syk-related tyrosine kinase
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T cell-specific protein-tyrosine kinase
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T-cell-specific kinase
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Tyrosine kinase ARG
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Tyrosine kinase lck
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Tyrosine kinase p56lck
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Tyrosine phosphokinase
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Tyrosine protein kinase
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Tyrosine protein kinase p56lck
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Tyrosine-protein kinase brk
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Tyrosine-protein kinase CTK
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Tyrosine-protein kinase Lyk
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Tyrosine-protein kinase TYRO 10
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Tyrosine-specific protein kinase
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Tyrosylprotein kinase
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v-fps Protein-tyrosine kinase
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YES related kinase
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Goddard, J.M.; Weiland, J.J.; Capecchi, M.R.
Isolation and characterization of Caenorhabditis elegans DNA sequences homologous to the v-abl oncogene
Proc. Natl. Acad. Sci. USA
83
2172-2176
1986
Caenorhabditis elegans (P03949), Caenorhabditis elegans
brenda
Krishna, S.; Maduzia, L.L.; Padgett, R.W.
Specificity of TGFbeta signaling is conferred by distinct type I receptors and their associated SMAD proteins in Caenorhabditis elegans
Development
126
251-260
1999
Caenorhabditis elegans (Q09488)
brenda
Estevez, M.; Attisano, L.; Wrana, J.L.; Albert, P.S.; Massague, J.; Riddle, D.L.
The daf-4 gene encodes a bone morphogenetic protein receptor controlling C. elegans dauer larva development
Nature
365
644-649
1993
Caenorhabditis elegans (P50488)
brenda
Georgi, L.L.; Albert, P.S.; Riddle, D.L.
Daf-1, a C. elegans gene controlling dauer larva development, encodes a novel receptor protein kinase
Cell
61
635-645
1990
Caenorhabditis elegans (P20792)
brenda