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Information on EC 2.7.1.35 - pyridoxal kinase and Organism(s) Arabidopsis thaliana and UniProt Accession Q8W1X2

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EC Tree
IUBMB Comments
Pyridoxine, pyridoxamine and various derivatives can also act as acceptors.
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This record set is specific for:
Arabidopsis thaliana
UNIPROT: Q8W1X2
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Word Map
The taxonomic range for the selected organisms is: Arabidopsis thaliana
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
pyridoxal kinase, pyridoxine kinase, pl kinase, ldpdxk, pyridoxal phosphokinase, stplk, pn kinase, hpl kinase, epl kinase 1, salt overly sensitive4, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
salt overly sensitive4
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kinase (phosphorylating), pyridoxal
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-
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kinase, pyridoxal (phosphorylating)
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PL kinase
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-
-
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PLK
-
-
-
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PM kinase
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-
-
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PN kinase
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-
-
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PN/PL/PM kinase
-
-
-
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pyridoxal 5-phosphate-kinase
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-
-
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pyridoxal kinase
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-
-
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pyridoxal kinase-like protein SOS4
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-
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pyridoxal phosphokinase
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-
-
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pyridoxamine kinase
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-
-
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pyridoxine kinase
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-
-
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pyridoxine/pyridoxal/pyridoxamine kinase
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-
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Sos4
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gene name, salt overly sensitive
vitamin B6 kinase
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-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
phospho group transfer
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-
-
-
PATHWAY SOURCE
PATHWAYS
-
-, -, -
SYSTEMATIC NAME
IUBMB Comments
ATP:pyridoxal 5'-phosphotransferase
Pyridoxine, pyridoxamine and various derivatives can also act as acceptors.
CAS REGISTRY NUMBER
COMMENTARY hide
9026-42-0
-
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
ATP + pyridoxal
ADP + pyridoxal 5'-phosphate
show the reaction diagram
-
-
-
-
ir
ATP + pyridoxamine
ADP + pyridoxamine 5'-phosphate
show the reaction diagram
-
-
-
-
ir
ATP + pyridoxine
ADP + pyridoxine 5'-phosphate
show the reaction diagram
-
-
-
-
ir
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
-
splice variant SOS4.1 (but not SOS4.2) is localized in chloroplasts
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
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root growth of a sos4 mutant is significantly decreased when grown on either 100 mM or 200 mM sucrose as compared to root growth on10 mM sucrose. The sos4 mutant plant accumulates phytoglycogen
physiological function
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the SOS4 pyridoxal kinase is required for maintenance of vitamin B6-mediated processes in chloroplasts. SOS4 is required for maintenance of phosphorylated B6 vitamer concentrations in chloroplasts
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
PDXK_ARATH
309
0
34043
Swiss-Prot
other Location (Reliability: 3)
PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
plants lacking enzyme activity display chlorosis and reduced plant size, and hypersensitivity to NaCl and sucrose. Mutant has higher level of pyridoxine, pyridoxamine, and pyridoxal 5'-phosphate. Mutant shows higher activity of pyridoxine/pyridoxamine 5'-phosphate oxidase as well as of the vitamin B6 de novo pathway enzyme Pdx1 and increased total vitamin B6 levels
APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
agriculture
plants lacking enzyme activity display chlorosis and reduced plant size, and hypersensitivity to NaCl and sucrose. Mutant has higher level of pyridoxine, pyridoxamine, and pyridoxal 5'-phosphate. Mutant shows higher activity of pyridoxine/pyridoxamine 5'-phosphate oxidase as well as of the vitamin B6 de novo pathway enzyme Pdx1 and increased total vitamin B6 levels
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Gonzalez, E.; Danehower, D.; Daub, M.E.
Vitamer levels, stress response, enzyme activity, and gene regulation of Arabidopsis lines mutant in the pyridoxine/pyridoxamine 5-phosphate oxidase (PDX3) and the pyridoxal kinase (SOS4) genes involved in the vitamin B6 salvage pathway
Plant Physiol.
145
985-996
2007
Arabidopsis thaliana (Q8W1X2)
Manually annotated by BRENDA team
Rueschhoff, E.E.; Gillikin, J.W.; Sederoff, H.W.; Daub, M.E.
The SOS4 pyridoxal kinase is required for maintenance of vitamin B6-mediated processes in chloroplasts
Plant Physiol. Biochem.
63
281-291
2013
Arabidopsis thaliana
Manually annotated by BRENDA team