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Information on EC 2.7.1.113 - deoxyguanosine kinase and Organism(s) Dictyostelium discoideum and UniProt Accession Q54UT2

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EC Tree
IUBMB Comments
Deoxyinosine can also act as acceptor.
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This record set is specific for:
Dictyostelium discoideum
UNIPROT: Q54UT2
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The taxonomic range for the selected organisms is: Dictyostelium discoideum
The enzyme appears in selected viruses and cellular organisms
Reaction Schemes
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ATP
+
deoxyguanosine
=
ADP
+
dGMP
+
=
+
Synonyms
deoxyguanosine kinase, dguok, 2'-deoxyguanosine kinase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
(dihydroxypropoxymethyl)guanine kinase
-
-
-
-
2'-deoxyguanosine kinase
-
-
-
-
kinase, deoxyguanosine (phosphorylating)
-
-
-
-
NTP-deoxyguanosine 5'-phosphotransferase
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
phospho group transfer
-
-
-
-
PATHWAY SOURCE
PATHWAYS
-
-
SYSTEMATIC NAME
IUBMB Comments
ATP:deoxyguanosine 5'-phosphotransferase
Deoxyinosine can also act as acceptor.
CAS REGISTRY NUMBER
COMMENTARY hide
39471-28-8
-
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
ATP + deoxyadenosine
ADP + dAMP
show the reaction diagram
barely measurable phosphorylation of deoxyadenosine
-
-
?
ATP + deoxyguanosine
ADP + dGMP
show the reaction diagram
-
-
-
?
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.206
deoxyadenosine
-
0.0014
deoxyguanosine
-
TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0047
deoxyadenosine
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
DGK_DICDI
285
0
33193
Swiss-Prot
Mitochondrion (Reliability: 3)
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Sandrini, M.P.B.; Soederbom, F.; Mikkelsen, N.E.; Piskur, J.
Dictyostelium discoideum salvages purine deoxyribonucleosides by highly specific bacterial-like deoxyribonucleoside kinases
J. Mol. Biol.
369
653-664
2007
Dictyostelium discoideum (Q54UT2), Dictyostelium discoideum
Manually annotated by BRENDA team