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Information on EC 2.7.1.107 - diacylglycerol kinase (ATP) and Organism(s) Xenopus laevis and UniProt Accession Q7ZYJ3

for references in articles please use BRENDA:EC2.7.1.107
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EC Tree
IUBMB Comments
Involved in synthesis of membrane phospholipids and the neutral lipid triacylglycerol. Activity is stimulated by certain phospholipids [4,7]. In plants and animals the product 1,2-diacyl-sn-glycerol 3-phosphate is an important second messenger. cf. EC 2.7.1.174, diacylglycerol kinase (CTP).
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This record set is specific for:
Xenopus laevis
UNIPROT: Q7ZYJ3
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Word Map
The taxonomic range for the selected organisms is: Xenopus laevis
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
dgk, diacylglycerol kinase, dag kinase, dg kinase, dgkzeta, dagk, dgkalpha, dgk-zeta, diglyceride kinase, dgkepsilon, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
1,2-diacylglycerol kinase
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adenosine 5'-triphosphate:1,2-diacylglycerol 3-phosphotransferase
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arachidonoyl-specific diacylglycerol kinase
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ATP:diacylglycerol phosphotransferase
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DAGK
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DAGKalpha
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DG kinase
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DGK
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DGK-alpha
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DGK-theta
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DGKbeta
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DGKdelta
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DGKgamma
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DGKiota
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DGKksi
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diacylglycerol kinase
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diacylglycerol kinase (ATP dependent)
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diacylglycerol:ATP kinase
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diglyceride kinase
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kinase (phosphorylating), 1,2-diacylglycerol
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kinase, 1,2-diacylglycerol (phosphorylating)
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sn-1,2-diacylglycerol kinase
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
phospho group transfer
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SYSTEMATIC NAME
IUBMB Comments
ATP:1,2-diacyl-sn-glycerol 3-phosphotransferase
Involved in synthesis of membrane phospholipids and the neutral lipid triacylglycerol. Activity is stimulated by certain phospholipids [4,7]. In plants and animals the product 1,2-diacyl-sn-glycerol 3-phosphate is an important second messenger. cf. EC 2.7.1.174, diacylglycerol kinase (CTP).
CAS REGISTRY NUMBER
COMMENTARY hide
60382-71-0
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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
4beta-phorbol-12-myristate-13-acetate
enhances voltage-dependent opening of wild-type and cAMP/H+-uncoupled hyperpolarization activated, cyclic nucleotide-regulated channels. 4beta-Phorbol-12-myristate-13-acetate exerts its effects on channel gating via sequential activation ofprotein kinase C and diacylglycerol kinase coupled with upregulation of mitogen-activated protein kinase and phospholipase A2
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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UniProt
Manually annotated by BRENDA team
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
AGK_XENLA
428
0
47962
Swiss-Prot
Mitochondrion (Reliability: 3)
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Fogle, K.J.; Lyashchenko, A.K.; Turbendian, H.K.; Tibbs, G.R.
HCN pacemaker channel activation is controlled by acidic lipids downstream of diacylglycerol kinase and phospholipase A2
J. Neurosci.
27
2802-2814
2007
Xenopus laevis (Q7ZYJ3)
Manually annotated by BRENDA team