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L-kynurenine + glyoxylate
kynurenic acid + glycine + H2O
alpha-ketobutyrate is also a co-substrate
-
-
?
2-aminobutyrate + glyoxylate
?
-
-
-
?
3-hydroxy-DL-kynurenine + 2-oxoglutarate
xanthurenic acid + L-glutamate + H2O
-
-
-
?
3-hydroxykynurenine + glyoxylate
?
-
-
-
?
L-alanine + glyoxylate
?
-
-
-
?
L-asparagine + glyoxylate
?
KAT II has high transamination activity toward L-asparagine
-
-
?
L-cysteine + glyoxylate
?
-
-
-
?
L-glutamine + glyoxylate
?
-
-
-
?
L-histidine + glyoxylate
?
-
-
-
?
L-kynurenine + 2-oxo-4-methylthiobutyrate
kynurenic acid + L-methionine
-
-
-
?
L-kynurenine + 2-oxobutyrate
?
-
high activity
-
-
?
L-kynurenine + 2-oxobutyrate
kynurenic acid + 2-aminobutanoate
-
-
-
?
L-kynurenine + 2-oxobutyrate
kynurenic acid + 2-aminobutanoate + H2O
-
-
-
?
L-kynurenine + 2-oxocaproate
?
-
high activity, 2-oxocaproate is the best cosubstrate
-
-
?
L-kynurenine + 2-oxocaproic acid
?
-
-
-
?
L-kynurenine + 2-oxocaproic acid
kynurenic acid + 2-aminohexanoate
-
-
-
?
L-kynurenine + 2-oxoglutarate
4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate
-
very low activity with 2-oxogltarate
-
-
?
L-kynurenine + 2-oxoglutarate
?
poor cosubstrate for KAT III
-
-
?
L-kynurenine + 2-oxoglutarate
kynurenic acid + L-glutamate + H2O
L-kynurenine + 2-oxoisocaproic acid
4-(2-aminophenyl)-2,4-dioxobutanoate + L-leucine
-
-
-
?
L-kynurenine + 2-oxoleucine
?
-
moderate activity
-
-
?
L-kynurenine + 2-oxomethylthiobutyric acid
?
-
-
-
?
L-kynurenine + 2-oxovalerate
?
L-kynurenine + 2-oxovalerate
kynurenic acid + 2-aminopentanoate
-
-
-
?
L-kynurenine + 2-oxovaline
?
-
low activity
-
-
?
L-kynurenine + glyoxylate
?
L-kynurenine + glyoxylate
kynurenic acid + glycine + H2O
L-kynurenine + hydroxyphenylpyruvate
?
-
moderate activity
-
-
?
L-kynurenine + hydroxyphenylpyruvate
kynurenic acid + L-tyrosine
-
-
-
?
L-kynurenine + indol-3-pyruvate
?
-
moderate activity
-
-
?
L-kynurenine + indol-3-ylpyruvate
?
-
-
-
?
L-kynurenine + indole-3-pyruvate
kynurenic acid + L-tryptophan
-
-
-
?
L-kynurenine + mercaptopyruvate
?
L-kynurenine + mercaptopyruvate
kynurenic acid + ?
-
-
-
?
L-kynurenine + oxaloacetate
4-(2-aminophenyl)-2,4-dioxobutanoate + L-aspartate
-
moderate activity
-
-
?
L-kynurenine + oxaloacetate
?
-
-
-
?
L-kynurenine + oxaloacetate
kynurenic acid + L-aspartate + H2O
-
-
-
?
L-kynurenine + p-hydroxyphenylpyruvate
?
-
-
-
?
L-kynurenine + phenylpyruvate
4-(2-aminophenyl)-2,4-dioxobutanoate + L-phenylalanine
-
high activity
-
-
?
L-kynurenine + phenylpyruvate
?
L-kynurenine + phenylpyruvate
kynurenic acid + L-phenylalanine
-
-
-
?
L-kynurenine + pyruvate
4-(2-aminophenyl)-2,4-dioxobutanoate + L-alanine
-
moderate activity
-
-
?
L-kynurenine + pyruvate
?
poor cosubstrate for KAT III
-
-
?
L-kynurenine + pyruvate
kynurenic acid + L-alanine + H2O
-
-
-
?
L-lysine + glyoxylate
?
-
-
-
?
L-methionine + glyoxylate
?
-
-
-
?
L-phenylalanine + glyoxylate
?
-
-
-
?
L-serine + glyoxylate
?
-
-
-
?
L-tryptophan + glyoxylate
?
-
-
-
?
L-tyrosine + glyoxylate
?
-
-
-
?
additional information
?
-
L-kynurenine + 2-oxoglutarate
kynurenic acid + L-glutamate + H2O
-
-
-
-
?
L-kynurenine + 2-oxoglutarate
kynurenic acid + L-glutamate + H2O
-
-
-
?
L-kynurenine + 2-oxoglutarate
kynurenic acid + L-glutamate + H2O
-
-
-
?
L-kynurenine + 2-oxoglutarate
kynurenic acid + L-glutamate + H2O
-
-
-
?
L-kynurenine + 2-oxoglutarate
kynurenic acid + L-glutamate + H2O
highest activity with aspartate and glutamate as substrate, but also active with other amino acids
-
-
?
L-kynurenine + 2-oxovalerate
?
-
-
-
?
L-kynurenine + 2-oxovalerate
?
-
high activity
-
-
?
L-kynurenine + glyoxylate
?
-
-
-
?
L-kynurenine + glyoxylate
?
-
high activity
-
-
?
L-kynurenine + glyoxylate
kynurenic acid + glycine + H2O
-
-
-
?
L-kynurenine + glyoxylate
kynurenic acid + glycine + H2O
2-oxobutyrate is also a co-substrate
-
-
?
L-kynurenine + mercaptopyruvate
?
-
-
-
?
L-kynurenine + mercaptopyruvate
?
-
moderate activity
-
-
?
L-kynurenine + phenylpyruvate
?
-
-
-
?
L-kynurenine + phenylpyruvate
?
poor cosubstrate for KAT III
-
-
?
additional information
?
-
-
KAT I is most active with large neutral/aromatic/sulfur-containing amino acids, including L-glutamine, L-phenylalanine, L-leucine, L-kynurenine, L-tryptophan, L-methionine, L-tyrosine, L-histidine, L-cysteine, aminobutyrate, S-(1,1,2,2-tetrafluoroethyl)-L-cysteine, and S-(1,2-dichlorovinyl)-L-cysteine. The enzyme has detectable activity with Se-methylselenocysteine, 5-S-cysteinyldopamine, 5-S-cysteinyl-DOPA, L-asparagine, glycine, L-alanine, L-arginine, L-serine, and L-lysine. KAT I can use many 2-oxo acids as its amino group acceptors: 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate, 2-oxo-4-methylthiobutyrate, mercaptopyruvate, indo-3-pyruvate, 2-oxovalerate, 2-oxoleucine, 2-oxobutyrate, p-hydroxyphenylpyruvate, 2-oxoadipate, glyoxylate, oxaloacetate, 2-oxovaline, 2-oxoisoleucine, and pyruvate. All of them demonstrate the capacity to act as amino group acceptors, but 2-oxoglutarate, 2-oxoiosleucine, indol-3-ylpyruvate, 2-oxoadipate, and 2-oxovaline have very low activity. Although the activity of KAT I using oxaloacetate, phenylpyruvate, or pyruvate as an amino group acceptor is detectable, the specific activity with these three 2-oxo acids is so low that they are unlikely to be physiological co-substrates for human KAT I
-
-
?
additional information
?
-
-
KAT II is efficient in catalyzing the transamination of aminoadipate, L-kynurenine, L-methionine, and L-glutamate, and is less efficient in catalyzing L-tyrosine, L-phenylalanine, L-tryptophan, L-leucine, 3-hydroxykynurenine, L-glutamine, L-alanine, and aminobutyrate. KAT II is efficient in catalyzing the transamination of 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate, and alpha-oxo-gamma-methiol-butyric acid, and less efficient in catalyzing mercaptopyruvate, indol-3-ylpyruvate, 2-oxovalerate, 2-oxoleucine, 2-oxobutyrate, p-hydroxyphenylpyruvate, 2-oxoadipate, glyoxylate, oxaloacetate, 2-oxovaline, 2-oxoisoleucine, and pyruvate (in order of decreasing catalytic efficiency)
-
-
?
additional information
?
-
KAT III does not use L-valine, L-proline, L-threonine, L-leucine, L-isoleucine, L-glutamate, L-aspartate, L-arginine, and aminoadipate as substrates
-
-
?
additional information
?
-
-
KAT III does not use L-valine, L-proline, L-threonine, L-leucine, L-isoleucine, L-glutamate, L-aspartate, L-arginine, and aminoadipate as substrates
-
-
?
additional information
?
-
-
KAT III shows activity towards L-phenylalanine, L-kynurenine, L-tryptophan, 3-hydroxykynurenine, L-tyrosine, and L-histidine, L-methionine and L-cysteine, L-glutamine, L-asparagine, L-serine, L-alanine, aminobutyrate, and L-lysine. Glyoxylate, 2-oxocaproic acid, phenylpyruvate, 2-oxobutyrate, alpha-oxo-gamma-methiol-butyric acid, 2-oxovalerate, indo-3-pyruvate, p-hydroxyphenylpyruvate, mercaptopyruvate, and oxaloacetate are good amino group acceptors for KAT III and pyruvate, phenylpyruvate, while 2-oxoglutarate are poor co-substrates for the enzyme
-
-
?
additional information
?
-
-
KAT IV shows high transamination activity towards L-glutamate, L-aspartate, L-phenylalanine, L-tyrosine, and L-cysteine, and detectable activity towards L-tryptophan, 3-hydroxykynurenine, L-methionine, L-kynurenine, and L-asparagine. It can use 2-oxoglutarate, phenylpyruvate, 2-oxo-4-methylthiobutyrate, indol-3-ylpyruvate, hydroxyphenylpyruvate, mercaptopyruvate, 2-oxocaproic acid, oxaloacetate, 2-oxobutyrate, pyruvate, and glyoxylate as amino group acceptors. It also shows detectable activity towards other co-substrates, including 2-oxovalerate, 2-oxoleucine, 2-oxoadipate, 2-oxovaline, and 2-oxoisoleucine
-
-
?
additional information
?
-
-
cosubstrate specificity, overview. No or poor activity with 2-oxoadipate and 2-oxoisoleucine. Recombinant mouse KAT3/GTL selectively metabolizes selenomethionine to 2-oxo-gamma-methylselenobutyrate, KAT3/GTLis more efficient in transamination of both than is KAT1/GTK
-
-
-
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5.7
2-oxo-4-methylthiobutyrate
pH 7.5, 38°C
0.5 - 10.4
2-oxocaproic acid
5.3
2-oxoisocaproic acid
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.4
alpha-oxo-gamma-methiol-butyric acid
in 100 mM boric acid buffer, pH 9.0, at 45°C
1 - 1.6
hydroxyphenylpyruvate
0.5
indo-3-pyruvate
in 100 mM boric acid buffer, pH 9.0, at 45°C
3.6
Indole-3-pyruvate
pH 7.5, 38°C
6.2
L-alanine
in 100 mM boric acid buffer, pH 9.0, at 45°C
1.4
L-asparagine
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.7
L-cysteine
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.7
L-glutamine
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.7
L-histidine
in 100 mM boric acid buffer, pH 9.0, at 45°C
1.5
L-kynurenine
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.9
L-methionine
in 100 mM boric acid buffer, pH 9.0, at 45°C
1.1
L-phenylalanine
in 100 mM boric acid buffer, pH 9.0, at 45°C
3
L-serine
in 100 mM boric acid buffer, pH 9.0, at 45°C
7.1
L-tryptophan
in 100 mM boric acid buffer, pH 9.0, at 45°C
2.7
L-tyrosine
in 100 mM boric acid buffer, pH 9.0, at 45°C
2.4 - 3.2
Mercaptopyruvate
1
2-oxobutyrate
in 100 mM boric acid buffer, pH 9.0, at 45°C
42.2
2-oxobutyrate
pH 7.5, 38°C
0.5
2-oxocaproic acid
in 100 mM boric acid buffer, pH 9.0, at 45°C
10.4
2-oxocaproic acid
pH 7.5, 38°C
2.4
2-oxoglutarate
pH 7.5, 38°C
8.1
2-oxoglutarate
in 100 mM boric acid buffer, pH 9.0, at 45°C
1.2
2-oxovalerate
in 100 mM boric acid buffer, pH 9.0, at 45°C
10.9
2-oxovalerate
pH 7.5, 38°C
0.4
glyoxylate
in 100 mM boric acid buffer, pH 9.0, at 45°C
4.2
glyoxylate
pH 7.5, 38°C
1
hydroxyphenylpyruvate
in 100 mM boric acid buffer, pH 9.0, at 45°C
1.6
hydroxyphenylpyruvate
pH 7.5, 38°C
2.4
Mercaptopyruvate
in 100 mM boric acid buffer, pH 9.0, at 45°C
3.2
Mercaptopyruvate
pH 7.5, 38°C
0.9
oxaloacetate
pH 7.5, 38°C
4.9
oxaloacetate
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.6
phenylpyruvate
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.6
phenylpyruvate
-
recombinant enzyme, pH 7.5, 38°C
0.7
phenylpyruvate
pH 7.5, 38°C
8.3
pyruvate
pH 7.5, 38°C
10.6
pyruvate
in 100 mM boric acid buffer, pH 9.0, at 45°C
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
0.41
2-oxo-4-methylthiobutyrate
pH 7.5, 38°C
0.69 - 2.93
2-oxobutyrate
0.41 - 2.59
2-oxocaproic acid
0.37 - 0.53
2-oxoglutarate
0.74
2-oxoisocaproic acid
in 100 mM boric acid buffer, pH 9.0, at 45°C
1.02
alpha-oxo-gamma-methiol-butyric acid
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.41 - 1.48
hydroxyphenylpyruvate
1.03
indo-3-pyruvate
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.49
Indole-3-pyruvate
pH 7.5, 38°C
1.53
L-alanine
in 100 mM boric acid buffer, pH 9.0, at 45°C
2.93
L-asparagine
in 100 mM boric acid buffer, pH 9.0, at 45°C
1.3
L-cysteine
in 100 mM boric acid buffer, pH 9.0, at 45°C
2.27
L-glutamine
in 100 mM boric acid buffer, pH 9.0, at 45°C
2
L-histidine
in 100 mM boric acid buffer, pH 9.0, at 45°C
2.3
L-kynurenine
in 100 mM boric acid buffer, pH 9.0, at 45°C
2.43
L-methionine
in 100 mM boric acid buffer, pH 9.0, at 45°C
2.7
L-phenylalanine
in 100 mM boric acid buffer, pH 9.0, at 45°C
2.17
L-serine
in 100 mM boric acid buffer, pH 9.0, at 45°C
3.57
L-tryptophan
in 100 mM boric acid buffer, pH 9.0, at 45°C
1.03
L-tyrosine
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.44 - 3.28
Mercaptopyruvate
0.63 - 3.17
phenylpyruvate
0.69
2-oxobutyrate
pH 7.5, 38°C
2.93
2-oxobutyrate
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.41
2-oxocaproic acid
pH 7.5, 38°C
2.59
2-oxocaproic acid
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.37
2-oxoglutarate
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.53
2-oxoglutarate
pH 7.5, 38°C
0.13
2-oxovalerate
pH 7.5, 38°C
2.7
2-oxovalerate
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.19
glyoxylate
pH 7.5, 38°C
2.71
glyoxylate
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.41
hydroxyphenylpyruvate
pH 7.5, 38°C
1.48
hydroxyphenylpyruvate
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.44
Mercaptopyruvate
pH 7.5, 38°C
3.28
Mercaptopyruvate
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.32
oxaloacetate
pH 7.5, 38°C
3.68
oxaloacetate
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.63
phenylpyruvate
pH 7.5, 38°C
2.53
phenylpyruvate
in 100 mM boric acid buffer, pH 9.0, at 45°C
3.17
phenylpyruvate
-
recombinant enzyme, pH 7.5, 38°C
0.37
pyruvate
pH 7.5, 38°C
1.87
pyruvate
in 100 mM boric acid buffer, pH 9.0, at 45°C
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
0.07
2-oxo-4-methylthiobutyrate
pH 7.5, 38°C
0.02 - 2.93
2-oxobutyrate
0.04 - 5.18
2-oxocaproic acid
0.045 - 0.22
2-oxoglutarate
0.14
2-oxoisocaproic acid
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.01 - 2.25
2-oxovalerate
2.54
alpha-oxo-gamma-methiol-butyric acid
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.26 - 1.48
hydroxyphenylpyruvate
2.07
indo-3-pyruvate
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.13
Indole-3-pyruvate
pH 7.5, 38°C
0.25
L-alanine
in 100 mM boric acid buffer, pH 9.0, at 45°C
2.095
L-asparagine
in 100 mM boric acid buffer, pH 9.0, at 45°C
1.86
L-cysteine
in 100 mM boric acid buffer, pH 9.0, at 45°C
3.24
L-glutamine
in 100 mM boric acid buffer, pH 9.0, at 45°C
2.86
L-histidine
in 100 mM boric acid buffer, pH 9.0, at 45°C
2.7
L-methionine
in 100 mM boric acid buffer, pH 9.0, at 45°C
2.45
L-phenylalanine
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.72
L-serine
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.5
L-tryptophan
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.38
L-tyrosine
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.14 - 1.37
Mercaptopyruvate
0.96 - 5.28
phenylpyruvate
0.02
2-oxobutyrate
pH 7.5, 38°C
2.93
2-oxobutyrate
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.04
2-oxocaproic acid
pH 7.5, 38°C
5.18
2-oxocaproic acid
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.045
2-oxoglutarate
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.22
2-oxoglutarate
pH 7.5, 38°C
0.01
2-oxovalerate
pH 7.5, 38°C
2.25
2-oxovalerate
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.05
glyoxylate
pH 7.5, 38°C
6.78
glyoxylate
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.26
hydroxyphenylpyruvate
pH 7.5, 38°C
1.48
hydroxyphenylpyruvate
in 100 mM boric acid buffer, pH 9.0, at 45°C
1.53
L-kynurenine
in 100 mM boric acid buffer, pH 9.0, at 45°C
1.53
L-kynurenine
pH and temperature not specified in the publication
0.14
Mercaptopyruvate
pH 7.5, 38°C
1.37
Mercaptopyruvate
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.35
oxaloacetate
pH 7.5, 38°C
0.75
oxaloacetate
in 100 mM boric acid buffer, pH 9.0, at 45°C
0.96
phenylpyruvate
pH 7.5, 38°C
4.22
phenylpyruvate
in 100 mM boric acid buffer, pH 9.0, at 45°C
5.28
phenylpyruvate
-
recombinant enzyme, pH 7.5, 38°C
0.05
pyruvate
pH 7.5, 38°C
0.18
pyruvate
in 100 mM boric acid buffer, pH 9.0, at 45°C
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additional information
midpoint temperature of protein melting 68.8°C, calculated half life time value at 65°C 69.7 min
additional information
midpoint temperature of protein melting 68.8°C, calculated half life time value at 65°C 69.7 min
additional information
midpoint temperature of protein melting 68.8°C, calculated half life time value at 65°C 69.7 min
additional information
midpoint temperature of protein melting 68.8°C, calculated half life time value at 65°C 69.7 min
additional information
-
midpoint temperature of protein melting 68.8°C, calculated half life time value at 65°C 69.7 min
additional information
midpoint temperature of protein melting 64.8°C, calculated half life time value at 65°C 3.9 min
additional information
midpoint temperature of protein melting 64.8°C, calculated half life time value at 65°C 3.9 min
additional information
midpoint temperature of protein melting 64.8°C, calculated half life time value at 65°C 3.9 min
additional information
midpoint temperature of protein melting 64.8°C, calculated half life time value at 65°C 3.9 min
additional information
-
midpoint temperature of protein melting 64.8°C, calculated half life time value at 65°C 3.9 min
additional information
midpoint temperature of protein melting 65.9°C, calculated half life time value at 65°C 27.4 min
additional information
midpoint temperature of protein melting 65.9°C, calculated half life time value at 65°C 27.4 min
additional information
midpoint temperature of protein melting 65.9°C, calculated half life time value at 65°C 27.4 min
additional information
midpoint temperature of protein melting 65.9°C, calculated half life time value at 65°C 27.4 min
additional information
-
midpoint temperature of protein melting 65.9°C, calculated half life time value at 65°C 27.4 min
additional information
midpoint temperature of protein melting 66.5°C, calculated half life time value at 65°C 6.5 min
additional information
midpoint temperature of protein melting 66.5°C, calculated half life time value at 65°C 6.5 min
additional information
midpoint temperature of protein melting 66.5°C, calculated half life time value at 65°C 6.5 min
additional information
midpoint temperature of protein melting 66.5°C, calculated half life time value at 65°C 6.5 min
additional information
-
midpoint temperature of protein melting 66.5°C, calculated half life time value at 65°C 6.5 min
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Yu, P.; Li, Z.; Zhang, L.; Tagle, D.A.; Cai, T.
Characterization of kynurenine aminotransferase III, a novel member of a phylogenetically conserved KAT family
Gene
365
111-118
2006
Rattus norvegicus (Q58FK9), Homo sapiens (Q6YP21), Homo sapiens, Mus musculus (Q71RI9), Mus musculus
brenda
Han, Q.; Cai, T.; Tagle, D.A.; Li, J.
Structure, expression, and function of kynurenine aminotransferases in human and rodent brains
Cell. Mol. Life Sci.
67
353-368
2010
Homo sapiens, Mus musculus, Rattus norvegicus
brenda
Han, Q.; Robinson, H.; Cai, T.; Tagle, D.A.; Li, J.
Biochemical and structural properties of mouse kynurenine aminotransferase III
Mol. Cell. Biol.
29
784-793
2009
Mus musculus (Q71RI9), Mus musculus
brenda
Han, Q.; Robinson, H.; Cai, T.; Tagle, D.A.; Li, J.
Biochemical and structural characterization of mouse mitochondrial aspartate aminotransferase, a newly identified kynurenine aminotransferase-IV
Biosci. Rep.
31
323-332
2011
Mus musculus (P05202), Mus musculus
brenda
Han, Q.; Cai, T.; Tagle, D.; Li, J.
Thermal stability, pH dependence and inhibition of four murine kynurenine aminotransferases
BMC Biochem.
11
0019
2010
Mus musculus (P05202), Mus musculus (Q71RI9), Mus musculus (Q8BTY1), Mus musculus (Q9WVM8), Mus musculus
brenda
Yang, C.; Zhang, L.; Han, Q.; Liao, C.; Lan, J.; Ding, H.; Zhou, H.; Diao, X.; Li, J.
Kynurenine aminotransferase 3/glutamine transaminase L/cysteine conjugate beta-lyase 2 is a major glutamine transaminase in the mouse kidney
Biochem. Biophys. Rep.
8
234-241
2016
Mus musculus
brenda
Rossi, F.; Miggiano, R.; Ferraris, D.M.; Rizzi, M.
The synthesis of kynurenic acid in mammals an updated kynurenine aminotransferase structural KATalogue
Front. Mol. Biosci.
6
7-7
2019
Mus musculus (P05202), Mus musculus (Q71RI9), Homo sapiens (Q16773), Homo sapiens (Q8N5Z0), Homo sapiens
brenda