Reference on EC 2.6.1.5 - tyrosine transaminase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Gohda, E.; Pitot, H.C.
Purification and characterization of a factor catalyzing the conversion of the multiple forms of tyrosine aminotransferase from rat liver
J. Biol. Chem.
255
7371-7379
1980
Rattus norvegicus
Miller, J.E.; Litwack, G.
Purification, properties, and identity of liver mitochondrial tyrosine aminotransferase
J. Biol. Chem.
246
3234-3240
1971
Rattus norvegicus
Hargrove, J.L.; Granner, D.K.
Purification of the native form of tyrosine aminotransferase from rat liver
Anal. Biochem.
104
231-235
1980
Rattus norvegicus
Lee, K.L.; Roberson, L.E.; Kenney, F.T.
Properties of tyrosine aminotransferase from rat liver
Anal. Biochem.
95
188-193
1979
Rattus norvegicus
Hargrove, J.L.; Granner, D.K.
Physical properties, limited proteolysis, and acetylation of tyrosine aminotransferase from rat liver
J. Biol. Chem.
256
8012-8017
1981
Rattus norvegicus
Donner, P.; Wagner, H.; Krger, H.
Tyrosine aminotransferase from rat liver, a purification in three steps
Biochem. Biophys. Res. Commun.
80
766-772
1978
Rattus norvegicus
Iwasaki, Y.; Lamar, C.; Danenberg, K.; Pitot, H.C.
Studies on the induction and repression of enzymes in rat liver. Characterization and metabolic regulation of multiple forms of tyrosine aminotransferase
Eur. J. Biochem.
34
347-357
1973
Rattus norvegicus
Belarbi, A.; Bollack, C.; Befort, N.; Beck, J.P.; Beck, G.
Purification and characterization of rat liver tyrosine aminotransferase
FEBS Lett.
75
221-225
1977
Rattus norvegicus
Roewekamp, W.; Sekeris, C.E.
Purification and subunit structure of tyrosine aminotransferase from rat liver cytosol
FEBS Lett.
73
225-228
1977
Rattus norvegicus
Johnson, R.W.; Roberson, L.E.; Kenney, F.T.
Regulation of tyrosine aminotransferase in rat liver. X. Characterization and interconversion of the multiple enzyme forms
J. Biol. Chem.
248
4521-4527
1973
Rattus norvegicus
Miller, J.V.; Cuatrecasas, P.; Thompson, E.B.
Purification of tyrosine aminotransferase by affinity chromatography
Biochim. Biophys. Acta
276
407-415
1972
Rattus norvegicus
Jacoby, G.A.; La Du, B.N.
Studies on the specificity of tyrosine-alpha-ketoglutarate transaminase
J. Biol. Chem.
239
419-424
1964
Rattus norvegicus
Echetebu, C.O.
Some properties of tyrosine aminotransferase from Trichoderma viride
J. Gen. Microbiol.
128
2735-2738
1982
Trichoderma viride
-
De-Eknamkul, W.; Ellis, B.E.
Purification and characterization of tyrosine aminotransferase activities from Anchusa officinalis cell cultures
Arch. Biochem. Biophys.
257
430-438
1987
Anchusa officinalis
Dietrich, J.B.; Lorber, B.; Kern, D.
Expression of mammalian tyrosine aminotransferase in Saccharomyces cerevisiae and Escherichia coli. Purification to homogeneity and characterization of the enzyme overproduced in the bacteria
Eur. J. Biochem.
201
399-407
1991
Rattus norvegicus
Ohisalo, J.J.; Andersson, S.M.; Pispa, J.P.
Partial purification and properties of frog liver tyrosine aminotransferase
Biochem. J.
163
411-417
1977
Rana temporaria
Rege, A.A.
Purification and characterization of a tyrosine aminotransferase from Crithidia fasciculata
Mol. Biochem. Parasitol.
25
1-9
1987
Crithidia fasciculata
Echetebu, C.O.; Ifem, F.M.; Echetebu, Z.O.
Hepatic tyrosine aminotransferase from the rainbow lizard Agama agama: purification and some properties
Biochimie
69
223-230
1987
Agama agama
Belew, K.; Brady, T.
Tyrosine aminotransferase from Drosophila hydei salivary glands: characterization, purification and antibody production
Insect Biochem.
11
239-245
1981
Drosophila hydei
-
Ohisalo, J.J.; Pispa, J.P.
Heterogeneity of hepatic tyrosine aminotransferase. Separation of the multiple forms from rat and frog liver by isoelectro focussing and hydroxyapatite column chromatography and their partial characterization
Acta Chem. Scand. B
30
491-500
1976
Rana temporaria, Rattus norvegicus
Montemartini, M.; Santome, J.A.; Cazzulo, J.J.; Nowick, C.
Purification and partial structural and kinetic characterization of tyrosine aminotransferase from epimastigotes of Trypanosoma cruzi
Biochem. J.
292
901-906
1993
Trypanosoma cruzi
Presch, I.; Birnbacher, R.; Herkner, K.; Lubec, G.
The effect of estradiol and ovariectomy on tyrosine hydroxylase, tyrosine aminotransferase and phenylalanine hydroxylase
Life Sci.
60
479-484
1997
Rattus norvegicus
Bai, S.C.; Rogers, Q.R.; Wong, D.L.; Sampson, D.A.; Morris, J.G.
Vitamin B-6 deficiency and level of dietary protein affect hepatic tyrosine aminotransferase activity in cats
J. Nutr.
128
1995-2000
1998
Felis catus
Nimi, S.; Yamaguchi, T.; Hayakawa, T.
Effect of dexamethasone pretreatment on the dexamethasone-dependent induction of tyrosine aminotransferase activity in primary cultured rat hepatocytes
Biol. Pharm. Bull.
21
1009-1012
1998
Rattus norvegicus
Pickering, C.S.; Watkins, R.H.; Dickson, A.J.
Rat primary hepatocytes and H4 hepatoma cells display differential sensitivity to cyclic AMP at the level of expression of tyrosine aminotransferase
Biochem. Biophys. Res. Commun.
252
764-769
1998
Rattus norvegicus
Donohue, T.M., Jr.; Drey, M.L.; Zetterman, R.K.
Contrasting effects of acute and chronic ethanol administration on rat liver tyrosine aminotransferase
Alcohol
15
141-146
1998
Rattus norvegicus
Blankenfeldt, W.; Nowicki, C.; Montemartini-Kalisz, M.; Kalisz, H.M.; Hecht, H.J.
Crystal structure of Trypanosoma cruzi tyrosine aminotransferase: substrate specificity is influenced by cofactor binding mode
Protein Sci.
8
2406-2417
1999
Trypanosoma cruzi
Ko, T.P.; Wu, S.P.; Yang, W.Z.; Tsai, H.; Yuan, H.S.
Crystallization and preliminary crystallographic analysis of the Escherichia coli tyrosine aminotransferase
Acta Crystallogr. Sect. D
55
1474-1477
1999
Escherichia coli
Tabiri, H.Y.; Sato, K.; Takahashi, K.; Toyomizu, M.; Akiba, Y.
Hepatic tyrosine aminotransferase activity is affected by chronic heat stress and dietary tyrosine in broiler chickens
Br. Poult. Sci.
43
629-634
2002
Gallus gallus
Amin, M.R.; Onodera, R.; Khan, R.I.; Wallace, R.J.; Newbold, C.J.
Purification and properties of glutamate-phenylpyruvate aminotransferase from the ruminal protozoan Entodinium caudatum
Aust. J. Agric. Res.
55
991-997
2004
Entodinium caudatum
-
Johansson, M.; Johansson, N.; Lund, B.O.
Xenobiotics and the glucocorticoid receptor: additive antagonistic effects on tyrosine aminotransferase activity in rat hepatoma cells
Basic Clin. Pharmacol. Toxicol.
96
309-315
2005
Rattus norvegicus
Rehman, K.K.; Ayesha, Q.; Khan, A.A.; Ahmed, N.; Habibullah, C.M.
Tyrosine aminotransferase and gamma-glutamyl transferase activity in human fetal hepatocyte primary cultures under proliferative conditions
Cell Biochem. Funct.
22
89-96
2004
Homo sapiens
Sobrado, V.R.; Montemartini-Kalisz, M.; Kalisz, H.M.; De La Fuente, M.C.; Hecht, H.J.; Nowicki, C.
Involvement of conserved asparagine and arginine residues from the N-terminal region in the catalytic mechanism of rat liver and Trypanosoma cruzi tyrosine aminotransferases
Protein Sci.
12
1039-1050
2003
Rattus norvegicus (P04694), Trypanosoma cruzi (P33447)
Rothman, S.C.; Voorhies, M.; Kirsch, J.F.
Directed evolution relieves product inhibition and confers in vivo function to a rationally designed tyrosine aminotransferase
Protein Sci.
13
763-772
2004
Escherichia coli
Seetharamappa, J.; Oke, M.; Liu, H.; McMahon, S.A.; Johnson, K.A.; Carter, L.; Dorward, M.; Zawadzki, M.; Overton, I.M.; van Niekirk, C.A.; Graham, S.; Botting, C.H.; Taylor, G.L.; White, M.F.; Barton, G.J.; Coote, P.J.; Naismith, J.H.
Expression, purification, crystallization, data collection and preliminary biochemical characterization of methicillin-resistant Staphylococcus aureus Sar2028, an aspartate/tyrosine/phenylalanine pyridoxal-5-phosphate-dependent aminotransferase
Acta Crystallogr. Sect. F
F63
452-456
2007
Staphylococcus aureus (A0A163U8E7)
Sivaraman, S.; Kirsch, J.F.
The narrow substrate specificity of human tyrosine aminotransferase--the enzyme deficient in tyrosinemia type II
FEBS J.
273
1920-1929
2006
Homo sapiens
Dundjerski, J.; Brkljacic, J.; Elakovic, I.; Manitasevic, S.; Matic, G.
Mercury influences rat liver tyrosine aminotransferase activity and induction by dexamethasone
J. Appl. Toxicol.
26
187-190
2006
Rattus norvegicus
Minami-Hori, M.; Ishida-Yamamoto, A.; Katoh, N.; Takahashi, H.; Iizuka, H.
Richner-Hanhart syndrome: Report of a case with a novel mutation of tyrosine aminotransferase
J. Dermatol. Sci.
41
82-84
2006
Homo sapiens
Hazra, A.; Pyszczynski, N.; Dubois, D.C.; Almon, R.R.; Jusko, W.J.
Modeling receptor/gene-mediated effects of corticosteroids on hepatic tyrosine aminotransferase dynamics in rats: dual regulation by endogenous and exogenous corticosteroids
J. Pharmacokinet. Pharmacodyn.
34
643-667
2007
Rattus norvegicus
Hollaender-Czytko, H.; Grabowski, J.; Sandorf, I.; Weckermann, K.; Weiler, E.W.
Tocopherol content and activities of tyrosine aminotransferase and cystine lyase in Arabidopsis under stress conditions
J. Plant Physiol.
162
767-770
2005
Arabidopsis thaliana
Charfeddine, C.; Monastiri, K.; Mokni, M.; Laadjimi, A.; Kaabachi, N.; Perin, O.; Nilges, M.; Kassar, S.; Keirallah, M.; Guediche, M.N.; Kamoun, M.R.; Tebib, N.; Ben Dridi, M.F.; Boubaker, S.; Ben Osman, A.; Abdelhak, S.
Clinical and mutational investigations of tyrosinemia type II in Northern Tunisia: Identification and structural characterization of two novel TAT mutations
Mol. Genet. Metab.
88
184-191
2006
Homo sapiens
Rego, J.V.; Murta, S.M.; Nirde, P.; Nogueira, F.B.; de Andrade, H.M.; Romanha, A.J.
Trypanosoma cruzi: characterisation of the gene encoding tyrosine aminotransferase in benznidazole-resistant and susceptible populations
Exp. Parasitol.
118
111-117
2008
Trypanosoma cruzi (Q4E4E7), Trypanosoma cruzi
Panin, L.E.; Usynin, I.F.
Role of glucocorticoids and resident liver macrophages in induction of tyrosine aminotransferase
Biochemistry
73
305-309
2008
Rattus norvegicus
Ebara, S.; Nakao, M.; Tomoda, M.; Yamaji, R.; Watanabe, F.; Inui, H.; Nakano, Y.
Vitamin B12 deficiency results in the abnormal regulation of serine dehydratase and tyrosine aminotransferase activities correlated with impairment of the adenylyl cyclase system in rat liver
Br. J. Nutr.
99
503-510
2008
Rattus norvegicus
Peragon, J.; Barroso, J.; De la Higuera, M.; Lupianez, J.
Serine dehydratase and tyrosine aminotransferase activities increased by long-term starvation and recovery by refeeding in rainbow trout (Oncorhynchus mykiss)
J. Exp. Zool. Part A Ecol. Genet. Physiol.
309
25-34
2008
Oncorhynchus mykiss
Marciano, D.; Maugeri, D.A.; Cazzulo, J.J.; Nowicki, C.
Functional characterization of stage-specific aminotransferases from trypanosomatids
Mol. Biochem. Parasitol.
166
172-182
2009
Leishmania major
Battilana, J.; Costantini, L.; Emanuelli, F.; Sevini, F.; Segala, C.; Moser, S.; Velasco, R.; Versini, G.; Stella Grando, M.
The 1-deoxy-D: -xylulose 5-phosphate synthase gene co-localizes with a major QTL affecting monoterpene content in grapevine
Theor. Appl. Genet.
118
653-669
2009
Vitis vinifera x Vitis vinifera, Vitis vinifera x Vitis riparia
Crismaru, C.G.; Wybenga, G.G.; Szymanski, W.; Wijma, H.J.; Wu, B.; Bartsch, S.; de Wildeman, S.; Poelarends, G.J.; Feringa, B.L.; Dijkstra, B.W.; Janssen, D.B.
Biochemical properties and crystal structure of a beta-phenylalanine aminotransferase from Variovorax paradoxus
Appl. Environ. Microbiol.
79
185-195
2013
Variovorax paradoxus (H8WR05)
Prabhu, P.R.; Hudson, A.O.
Identification and partial characterization of an L-tyrosine aminotransferase (TAT) from Arabidopsis thaliana
Biochem. Res. Int.
2010
549572
2010
Arabidopsis thaliana (Q9LVY1), Arabidopsis thaliana
Grossmann, K.; Hutzler, J.; Tresch, S.; Christiansen, N.; Looser, R.; Ehrhardt, T.
On the mode of action of the herbicides cinmethylin and 5-benzyloxymethyl-1, 2-isoxazolines: putative inhibitors of plant tyrosine aminotransferase
Pest Manag. Sci.
68
482-492
2012
Arabidopsis thaliana
Riewe, D.; Koohi, M.; Lisec, J.; Pfeiffer, M.; Lippmann, R.; Schmeichel, J.; Willmitzer, L.; Altmann, T.
A tyrosine aminotransferase involved in tocopherol synthesis in Arabidopsis
Plant J.
71
850-859
2012
Arabidopsis thaliana
Lee, E.J.; Facchini, P.J.
Tyrosine aminotransferase contributes to benzylisoquinoline alkaloid biosynthesis in opium poppy
Plant Physiol.
157
1067-1078
2011
Papaver somniferum
Mehere, P.; Han, Q.; Lemkul, J.A.; Vavricka, C.J.; Robinson, H.; Bevan, D.R.; Li, J.
Tyrosine aminotransferase: biochemical and structural properties and molecular dynamics simulations
Protein Cell
1
1023-1032
2010
Mus musculus
Yoo, H.; Widhalm, J.; Qian, Y.; Maeda, H.; Cooper, B.; Jannasch, A.; Gonda, I.; Lewinsohn, E.; Rhodes, D.; Dudareva, N.
An alternative pathway contributes to phenylalanine biosynthesis in plants via a cytosolic tyrosine:phenylpyruvate aminotransferase
Nat. Commun.
4
2833
2013
Petunia x hybrida (V5M241)
Kim, Y.B.; Uddina, M.R.; Kim, Y.; Park, C.G.; Park, S.U.
Molecular cloning and characterization of tyrosine aminotransferase and hydroxyphenylpyruvate reductase, and rosmarinic acid accumulation in Scutellaria baicalensis
Nat. Prod. Commun.
9
1311-1314
2014
Scutellaria baicalensis (A0A0A7DPK0), Scutellaria baicalensis (A0A0A7DQ59), Scutellaria baicalensis
Nandi, S.S.; Zheng, H.; Sharma, N.M.; Shahshahan, H.R.; Patel, K.P.; Mishra, P.K.
Lack of miR-133a decreases contractility of diabetic hearts a role for novel cross talk between tyrosine aminotransferase and tyrosine hydroxylase
Diabetes
65
3075-3090
2016
Rattus norvegicus (P04694), Mus musculus (Q8QZR1)
Lim, W.; Song, G.
Characteristics, tissue-specific expression, and hormonal regulation of expression of tyrosine aminotransferase in the avian female reproductive tract
Domest. Anim. Endocrinol.
57
10-20
2016
Gallus gallus (E1C5G9), Gallus gallus
Sasidharan, S.; Saudagar, P.
Biochemical and structural characterization of tyrosine aminotransferase suggests broad substrate specificity and a two-state folding mechanism in Leishmania donovani
FEBS Open Bio
9
1769-1783
2019
Leishmania donovani (A0A5B8TZA8), Leishmania donovani
Wang, M.; Toda, K.; Maeda, H.A.
Biochemical properties and subcellular localization of tyrosine aminotransferases in Arabidopsis thaliana
Phytochemistry
132
16-25
2016
Arabidopsis thaliana (Q67Y55), Arabidopsis thaliana (Q9FN30), Arabidopsis thaliana
Wang, H.; Dong, Q.; Duan, D.; Zhao, S.; Li, M.; van Nocker, S.; Ma, F.; Mao, K.
Comprehensive genomic analysis of the tyrosine aminotransferase (TAT) genes in apple (Malus domestica) allows the identification of MdTAT2 conferring tolerance to drought and osmotic stresses in plants
Plant Physiol. Biochem.
133
81-91
2018
Malus domestica (A0A2K9VNZ8), Malus domestica (A0A2K9VP07), Malus domestica (A0A2K9VP55), Malus domestica
Kaledin, V.; Ilnitskaya, S.; Popova, N.; Koval, O.; Pyshnaya, I.; Gulyaeva, L.
Induction of tyrosine aminotransferase in mice is inhibited by the activated metabolites of ortho-aminoazotoluene
Russ. J. Genet. Appl. Res.
6
91-98
2016
Mus musculus
-
Sasidharan, S.; Saudagar, P.
Mapping N- and C-terminals of Leishmania donovani tyrosine aminotransferase by gene truncation strategy a functional study using in vitro and in silico approaches
Sci. Rep.
10
12463
2020
Leishmania donovani (A0A5B8TZA8), Leishmania donovani
Ru, M.; Wang, K.; Bai, Z.; Peng, L.; He, S.; Wang, Y.; Liang, Z.
A tyrosine aminotransferase involved in rosmarinic acid biosynthesis in Prunella vulgaris L
Sci. Rep.
7
4892
2017
Prunella vulgaris
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