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(R)-3-amino-2-methylpropanoate + 2-oxo-n-butanoate
2-methyl-3-oxopropanoate + 2-amino-n-butanoate
-
-
-
-
?
(R)-3-amino-2-methylpropanoate + 2-oxo-n-pentanoate
2-methyl-3-oxopropanoate + norvaline
-
-
-
-
?
(R)-3-amino-2-methylpropanoate + glyoxylate
2-methyl-3-oxopropanoate + glycine
(R)-3-amino-2-methylpropanoate + oxaloacetate
2-methyl-3-oxopropanoate + L-aspartate
(R)-3-amino-2-methylpropanoate + pyruvate
2-methyl-3-oxopropanoate + L-alanine
(S)-2-aminobutyrate + pyruvate
2-oxobutanoate + L-alanine
-
-
-
-
?
4-aminobutanoate + pyruvate
succinic semialdehyde + L-alanine
-
transamination at 19% the rate of (R)-3-amino-2-methylpropanoate
-
-
?
5-aminolevulinic acid + pyruvate
5-oxolevulinic acid + L-alanine
-
-
-
-
?
arginine + pyruvate
2-oxo-5-guanidinovaleric acid + L-alanine
-
transamination at 40% the rate of (R)-3-amino-2-methylpropanoate
-
-
?
beta-alanine + pyruvate
malonic semialdehyde + L-alanine
DL-3-amino-n-butanoate + pyruvate
3-oxobutanoate + L-alanine
-
-
-
-
?
DL-alpha-ethyl-beta-alanine + pyruvate
2-ethyl-3-oxopropanoate + L-alanine
-
transamination at 33% the rate of (R)-3-amino-2-methylpropanoate
-
-
?
glycine + pyruvate
glyoxylate + L-alanine
-
-
-
-
?
NG,NG'-dimethyl-(S)-arginine + pyruvate
? + L-alanine
-
-
-
-
?
additional information
?
-
(R)-3-amino-2-methylpropanoate + glyoxylate
2-methyl-3-oxopropanoate + glycine
-
-
-
-
?
(R)-3-amino-2-methylpropanoate + glyoxylate
2-methyl-3-oxopropanoate + glycine
-
with 90% efficiency compared to pyruvate
-
-
r
(R)-3-amino-2-methylpropanoate + glyoxylate
2-methyl-3-oxopropanoate + glycine
-
with 50% efficiency compared to pyruvate
-
-
?
(R)-3-amino-2-methylpropanoate + oxaloacetate
2-methyl-3-oxopropanoate + L-aspartate
-
-
-
-
?
(R)-3-amino-2-methylpropanoate + oxaloacetate
2-methyl-3-oxopropanoate + L-aspartate
-
with 63% efficiency compared to pyruvate
-
-
r
(R)-3-amino-2-methylpropanoate + pyruvate
2-methyl-3-oxopropanoate + L-alanine
-
best substrate among omega-amino acids, highly specific for D-isomer
-
r
(R)-3-amino-2-methylpropanoate + pyruvate
2-methyl-3-oxopropanoate + L-alanine
-
first step in aminoisobutyrate metabolism
-
?
(R)-3-amino-2-methylpropanoate + pyruvate
2-methyl-3-oxopropanoate + L-alanine
-
-
-
?
(R)-3-amino-2-methylpropanoate + pyruvate
2-methyl-3-oxopropanoate + L-alanine
-
first step in aminoisobutyrate metabolism
-
?
(R)-3-amino-2-methylpropanoate + pyruvate
2-methyl-3-oxopropanoate + L-alanine
-
-
-
?
(R)-3-amino-2-methylpropanoate + pyruvate
2-methyl-3-oxopropanoate + L-alanine
-
-
-
?
(R)-3-amino-2-methylpropanoate + pyruvate
2-methyl-3-oxopropanoate + L-alanine
-
-
i.e. methylmalonyl semialdehyde
?
(R)-3-amino-2-methylpropanoate + pyruvate
2-methyl-3-oxopropanoate + L-alanine
-
first step in aminoisobutyrate metabolism
-
?
(R)-3-amino-2-methylpropanoate + pyruvate
2-methyl-3-oxopropanoate + L-alanine
-
-
-
?
(R)-3-amino-2-methylpropanoate + pyruvate
2-methyl-3-oxopropanoate + L-alanine
-
first step in aminoisobutyrate metabolism
-
?
beta-alanine + pyruvate
malonic semialdehyde + L-alanine
-
-
-
-
?
beta-alanine + pyruvate
malonic semialdehyde + L-alanine
-
transamination at 66% the rate of (R)-3-amino-2-methylpropanoate
-
-
?
beta-alanine + pyruvate
malonic semialdehyde + L-alanine
-
transamination at 66% the rate of (R)-3-amino-2-methylpropanoate
-
-
?
additional information
?
-
-
-
-
-
?
additional information
?
-
-
-
-
-
?
additional information
?
-
-
overview
-
-
?
additional information
?
-
-
overview
-
-
?
additional information
?
-
-
overview
-
-
?
additional information
?
-
-
no substrate: 2-oxoglutarate
-
-
?
additional information
?
-
-
no substrate: 2-oxoglutarate
-
-
?
additional information
?
-
-
no substrate: 2-oxoglutarate
-
-
?
additional information
?
-
-
gamma-aminobutanoate is neither substrate nor inhibitor
-
-
?
additional information
?
-
-
no substrate: phenylpyruvate
-
-
?
additional information
?
-
-
no substrate: phenylpyruvate
-
-
?
additional information
?
-
-
no substrate: 2-oxoglutarate
-
-
?
additional information
?
-
-
no substrate: 5-amino-n-pentanoate, 6-aminohexanoate, DL-3-aminobutyrate, oxaloacetate
-
-
?
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(R)-3-amino-2-methylpropanoate + pyruvate
2-methyl-3-oxopropanoate + L-alanine
(R)-3-amino-2-methylpropanoate + pyruvate
2-methyl-3-oxopropanoate + L-alanine
-
first step in aminoisobutyrate metabolism
-
?
(R)-3-amino-2-methylpropanoate + pyruvate
2-methyl-3-oxopropanoate + L-alanine
-
first step in aminoisobutyrate metabolism
-
?
(R)-3-amino-2-methylpropanoate + pyruvate
2-methyl-3-oxopropanoate + L-alanine
-
first step in aminoisobutyrate metabolism
-
?
(R)-3-amino-2-methylpropanoate + pyruvate
2-methyl-3-oxopropanoate + L-alanine
-
first step in aminoisobutyrate metabolism
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
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(R)-3-Amino-2-methylpropanoate
-
beta-alanine as substrate
(S)-2-aminobutyrate
-
beta-alanine as substrate
(S)-alanine
-
with beta-alanine + glyoxylate as substrate, not (R)-isomer
5-aminolevulinic acid
-
beta-alanine as substrate
5-Thiouracil
-
1 M, not 2-thiouracil
alpha-fluoro-beta-alanine
Amino-oxyacetate
-
strong
beta-Alanine
-
with (S)-alanine + glyoxylate as substrate
glyoxylate
-
at high concentrations
NG,NG'-dimethyl-(S)-arginine
-
beta-alanine as substrate
5-fluorouracil
-
strong, kinetics
6-Azauracil
-
weak, kinetics, not reversible by pyridoxal phosphate
alpha-fluoro-beta-alanine
-
-
alpha-fluoro-beta-alanine
-
kinetics
gabaculine
-
-
gabaculine
-
i.e. 5-amino-1,3-cyclohexadienylcarboxylate, strong, irreversible, beta-alanine or pyruvate protects, 4-aminobutyrate to a lesser extent, not 2-oxoglutarate
pyruvate
-
-
pyruvate
-
at high concentrations
additional information
-
no inhibitor: aminouracil; no inhibitor: precursors of beta-alanine or (R)-3-amino-2-methylpropanoate, i.e. orotic acid, uracil, thymine
-
additional information
-
no inhibitor: dihydrothymine, dihydrouracil, N-carbamoyl-beta-alanine, N-carbamoyl-DL-3-aminoisobutyrate; no inhibitor: precursors of beta-alanine or (R)-3-amino-2-methylpropanoate, i.e. orotic acid, uracil, thymine
-
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Tamaki, N.; Sakata, S.F.; Matsuda, K.
Purification, properties, and sequencing of aminoisobutyrate aminotransferases from rat liver
Methods Enzymol.
324
376-389
2000
Rattus norvegicus
brenda
Kaneko, M.; Fujimoto, S.; Kikugawa, M.; Tamaki, N.
Irreversible inhibition of D-3-aminoisobutyrate-pyruvate aminotransferase by gabaculine
FEBS Lett.
276
115-118
1990
Rattus norvegicus
brenda
Kaneko, M.; Kontani, Y.; Kikugawa, M.; Tamaki, N.
Inhibition of D-3-aminoisobutyrate-pyruvate aminotransferase by 5-fluorouracil and alpha-fluoro-beta-alanine
Biochim. Biophys. Acta
1122
45-49
1992
Rattus norvegicus
brenda
Tamaki, N.; Kaneko, M.; Mizota, C.; Kikugawa, M.; Fujimoto, S.
Purification, characterization and inhibition of D-3-aminoisobutyrate aminotransferase from the rat liver
Eur. J. Biochem.
189
39-45
1990
Rattus norvegicus
brenda
Kakimoto, Y.; Taniguchi, K.; Sano, I.
D-beta-Aminoisobutyrate:pyruvate aminotransferase in mammalian liver and excretion of beta-aminoisobutyrate by man
J. Biol. Chem.
244
335-340
1969
Cavia porcellus, Homo sapiens, Rattus norvegicus, Sus scrofa
brenda
Ueno, S.I.; Morino, H.; Sano, A.; Kakimoto, Y.
Purification and characterization of D-3-aminoisobutyrate-pyruvate aminotransferase from rat liver
Biochim. Biophys. Acta
1033
169-175
1990
Rattus norvegicus
brenda
Kontani, M.; Kaneko, M.; Kikugawa, M.; Fujimoto, S.; Tamaki, N.
Identity of D-3-aminoisobutyrate-pyruvate aminotransferase with alanine-glyoxylate aminotransferase 2
Biochim. Biophys. Acta
1156
161-166
1993
Rattus norvegicus
brenda
Abe, M.; Ochi, S.; Mori, Y.; Yamazaki, K.; Ishimaru, T.; Yoshino, Y.; Fukuhara, R.; Tanimukai, S.; Matsuda, S.; Ueno, S.
Distribution of D-3-aminoisobutyrate-pyruvate aminotransferase in the rat brain
BMC Neurosci.
15
53
2014
Rattus norvegicus (Q64565)
brenda