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Information on EC 2.4.2.51 - anthocyanidin 3-O-glucoside 2'''-O-xylosyltransferase and Organism(s) Arabidopsis thaliana and UniProt Accession Q9LVW3
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2.4.2.51 anthocyanidin 3-O-glucoside 2'''-O-xylosyltransferaseIUBMB Comments
Isolated from the plants Matthiola incana (stock) and Arabidopsis thaliana (mouse-eared cress) . The enzyme has similar activity with the 3-glucosides of pelargonidin, cyanidin, delphinidin, quercetin and kaempferol as well as with cyanidin 3-O-rhamnosyl-(1->6)-glucoside and cyanidin 3-O-(6-acylglucoside). There is no activity with other UDP-sugars or with cyanidin 3,5-diglucoside.
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The taxonomic range for the selected organisms is: Arabidopsis thaliana
The enzyme appears in selected viruses and cellular organisms
The enzyme appears in selected viruses and cellular organisms
Reaction Schemes
Synonyms
ugt79b1, anthocyanin 3-o-glucoside 2''-o-xylosyltransferase, 
more
topSYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
SYSTEMATIC NAME
IUBMB Comments
UDP-alpha-D-xylose:anthocyanidin-3-O-beta-D-glucoside 2'''-O-xylosyltransferase
Isolated from the plants Matthiola incana (stock) [1] and Arabidopsis thaliana (mouse-eared cress) [2]. The enzyme has similar activity with the 3-glucosides of pelargonidin, cyanidin, delphinidin, quercetin and kaempferol as well as with cyanidin 3-O-rhamnosyl-(1->6)-glucoside and cyanidin 3-O-(6-acylglucoside). There is no activity with other UDP-sugars or with cyanidin 3,5-diglucoside.
SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
UDP-alpha-D-xylose + cyanidin 3-O-alpha-L-rhamnosyl-(1->6)-beta-D-glucoside
UDP + cyanidin 3-O-beta-D-xylosyl-(1->2)-alpha-L-rhamnosyl-(1->6)-beta-D-glucoside
-
-
-
?
UDP-alpha-D-xylose + cyanidin 3-O-beta-D-glucoside
UDP + cyanidin 3-O-beta-D-sambubioside
-
-
-
?
UDP-alpha-D-xylose + delphinidin 3-O-beta-D-glucoside
UDP + delphinidin 3-O-beta-D-sambubioside
-
-
-
?
UDP-alpha-D-xylose + kaempferol 3-O-alpha-L-rhamnosyl-(1->6)-beta-D-glucoside
UDP + kaempferol 3-O-beta-D-xylosyl-(1->2)-[alpha-L-rhamnosyl-(1->6)]-beta-D-glucoside
-
-
-
?
UDP-alpha-D-xylose + kaempferol 3-O-beta-D-glucoside
UDP + kaempferol 3-O-beta-D-xylosyl-(1->2)-beta-D-glucoside
best substrate
-
-
?
UDP-alpha-D-xylose + pelargonidin 3-O-beta-D-glucoside
UDP + pelargonidin 3-O-beta-D-sambubioside
-
-
-
?
UDP-alpha-D-xylose + quercetin 3-O-beta-D-glucoside
UDP + quercetin 3-O-beta-D-sambubioside
-
-
-
?
UDP-D-xylose + cyanidin 3-O-(alpha-L-rhamnosyl-(1->6)-beta-D-glucoside)
UDP + cyanidin 3-O-(beta-D-xylosyl-1(->2)[alpha-L-rhamnosyl-(1->6)]-beta-D-glucoside)
-
-
-
?
UDP-D-xylose + cyanidin 3-O-beta-D-glucoside
UDP + cyanidin 3-O-(beta-D-xylosyl-(1->2)-beta-D-glucoside)
-
-
-
?
UDP-D-xylose + delphinidin 3-O-beta-D-glucoside
UDP + delphinidin 3-O-(beta-D-xylosyl-(1->2)-beta-D-glucoside)
-
-
-
?
UDP-D-xylose + kaempferol 3-O-alpha-L-rhamnosyl-(1->6)-beta-D-glucoside
UDP + kaempferol 3-O-(beta-D-xylosyl-(1->2)[alpha-L-rhamnosyl-(1->6)]-beta-D-glucoside)
-
-
-
?
UDP-D-xylose + kaempferol 3-O-beta-D-glucoside
UDP + kaempferol 3-O-(beta-D-xylosyl-(1->2)-beta-D-glucoside)
-
-
-
?
UDP-D-xylose + pelargonidin 3-O-beta-D-glucoside
UDP + pelargonidin 3-O-(beta-D-xylosyl-(1->2)-beta-D-glucoside)
-
-
-
?
UDP-D-xylose + quercetin 3-O-beta-D-glucoside
UDP + quercetin 3-O-(beta-D-xylosyl-(1->2)-beta-D-glucoside)
-
-
-
?
additional information
?
-
enzyme converts cyanidin 3-O-glucoside to cyanidin 3-O-xylosyl(1-2)glucoside. Enzyme recognizes 3-O-glucosylated anthocyanidins/flavonols and uridine diphosphate (UDP)-xylose
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-
?
additional information
?
-
-
enzyme converts cyanidin 3-O-glucoside to cyanidin 3-O-xylosyl(1-2)glucoside. Enzyme recognizes 3-O-glucosylated anthocyanidins/flavonols and uridine diphosphate (UDP)-xylose
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-
?
additional information
?
-
UGT79B1 recognizes 3-O-glucosylated anthocyanidins/flavonols and UDP-xylose, but not 3,5-O-diglucosylated anthocyanidins, substrate specificity, overview. No activity with cyanidin 3-O-rhamnoside, cyanidin 3,5-O-diglucoside, cyanidin 3-O-6''-O-4-coumaroylglucoside-5-O-glucoside, cyanidin 3-O-6''-O-p-coumaroylglucoside, kaempferol 3-O-rhanoside, and kaempferol 3-O-glucoside-7-O-rhamnoside. The enzyme is absolutely specific for UDP-xylose as donar substrate, no activity with UDP-arabinose, UDP-galactose, UDP-glucose, UDP-glucuronic acid, and UDP-rhamnose
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-
?
additional information
?
-
-
UGT79B1 recognizes 3-O-glucosylated anthocyanidins/flavonols and UDP-xylose, but not 3,5-O-diglucosylated anthocyanidins, substrate specificity, overview. No activity with cyanidin 3-O-rhamnoside, cyanidin 3,5-O-diglucoside, cyanidin 3-O-6''-O-4-coumaroylglucoside-5-O-glucoside, cyanidin 3-O-6''-O-p-coumaroylglucoside, kaempferol 3-O-rhanoside, and kaempferol 3-O-glucoside-7-O-rhamnoside. The enzyme is absolutely specific for UDP-xylose as donar substrate, no activity with UDP-arabinose, UDP-galactose, UDP-glucose, UDP-glucuronic acid, and UDP-rhamnose
-
-
?
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
UDP-alpha-D-xylose + cyanidin 3-O-beta-D-glucoside
UDP + cyanidin 3-O-beta-D-sambubioside
-
-
-
?
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
evolution
flavonoid UGT phylogenetic tree, UGT79B1 belongs to a cluster in which UGTs transfer a glycosyl group to a sugar moiety of flavonoid glycosides
malfunction
anthocyanin is drastically reduced in ugt79b1 knockout mutants
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable).
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). AXYLT_ARATH
468
0
52048
Swiss-Prot
other Location (Reliability: 3)
PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
additional information
additional information
construction of transposon insertion mutants of UGT79B1
additional information
-
construction of transposon insertion mutants of UGT79B1
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
gene ugt79b1, DNA and amino acid sequence determination and analysis, expression analysis and phylogenetic analysis, recombinant expression as His-tagged protein in Escherichia coli
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Yonekura-Sakakibara, K.; Fukushima, A.; Nakabayashi, R.; Hanada, K.; Matsuda, F.; Sugawara, S.; Inoue, E.; Kuromori, T.; Ito, T.; Shinozaki, K.; Wangwattana, B.; Yamazaki, M.; Saito, K.
Two glycosyltransferases involved in anthocyanin modification delineated by transcriptome independent component analysis in Arabidopsis thaliana
Plant J.
69
154-167
2012
Arabidopsis thaliana (Q9LVW3), Arabidopsis thaliana
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