Information on EC 2.4.2.47 - arabinofuranan 3-O-arabinosyltransferase

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The expected taxonomic range for this enzyme is: Mycobacterium tuberculosis

EC NUMBER
COMMENTARY hide
2.4.2.47
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RECOMMENDED NAME
GeneOntology No.
arabinofuranan 3-O-arabinosyltransferase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
Adds an alpha-D-arabinofuranosyl group from trans,octacis-decaprenylphospho-beta-D-arabinofuranose at the 3-O-position of an alpha-(1->5)-arabinofuranan chain attached to a beta-(1->5)-galactofuranan chain
show the reaction diagram
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
mycolyl-arabinogalactan-peptidoglycan complex biosynthesis
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SYSTEMATIC NAME
IUBMB Comments
alpha-(1->5)-arabinofuranan:trans,octacis-decaprenylphospho-beta-D-arabinofuranose 3-O-alpha-D-arabinofuranosyltransferase
Isolated from Mycobacterium smegmatis. Involved in the formation of the cell wall in mycobacteria.
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
metabolism
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(2Z,6Z)-farnesylphospho-alpha-D-arabinofuranoside + octyl (alpha-D-Araf)2-(1->3,5)-alpha-D-Araf-(1->5)-alpha-D-Araf-(1->5)-alpha-D-Araf
?
show the reaction diagram
(2Z,6Z)-farnesylphospho-alpha-D-arabinofuranoside + octyl alpha-D-Araf-(1->5)-alpha-D-Araf-(1->5)-alpha-D-Araf-(1->5)-alpha-D-Araf-(1->5)-alpha-D-Araf
?
show the reaction diagram
beta-D-arabinofuranosyl-1-monophosphoryl-decaprenol + alpha-D-arabinofuranosyl-(1->5)-alpha-D-arabinofuranosyl-(1->5)-alpha-D-arabinofuranosyl-(1->5)-alpha-arabinofuranosyl-(1->5)-alpha-D-arabinofuranosyl-O-(CH2)8NH2
?
show the reaction diagram
decaprenylphospho-alpha-D-arabinofuranoside + octyl alpha-D-Araf-(1->5)-alpha-D-Araf-(1->5)-alpha-D-Araf-(1->5)-alpha-D-Araf-(1->5)-alpha-D-Araf
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show the reaction diagram
ditrans,tetracis-heptaprenylphospho-alpha-D-arabinofuranoside + octyl alpha-D-Araf-(1->5)-alpha-D-Araf-(1->5)-alpha-D-Araf-(1->5)-alpha-D-Araf-(1->5)-alpha-D-Araf
?
show the reaction diagram
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?
additional information
?
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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
additional information
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AftC is active only when reconstituted in a proteoliposome
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LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
SUBUNITS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
metal affinity column column chromatography
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Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
expressed in Mycobacterium smegmatis mc2155/pJAM/Rv2673 cells
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expressed in Mycobacterium smegmatis strain mc2155 MSMEG2785
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