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Information on EC 2.4.1.356 - glucosyl-dolichyl phosphate glucuronosyltransferase

for references in articles please use BRENDA:EC2.4.1.356
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EC Tree
IUBMB Comments
The enzyme, characterized from the halophilic archaeon Haloferax volcanii, participates in the protein N-glycosylation pathway. Dolichol used by archaea is different from that used by eukaryotes. It is much shorter (C55-C60) and is alpha,omega-saturated. However, in vitro the enzyme was also able to act on a substrate with an unsaturated end.
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The expected taxonomic range for this enzyme is: Archaea, Bacteria
Reaction Schemes
+
an archaeal dolichyl alpha-D-glucosyl phosphate
=
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an archaeal dolichyl beta-D-glucuronosyl-(1->4)-alpha-D-glucosyl phosphate
Synonyms
aglG, HVO_1529, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
UDP-alpha-D-glucuronate + an archaeal dolichyl alpha-D-glucosyl phosphate = UDP + an archaeal dolichyl beta-D-glucuronosyl-(1->4)-alpha-D-glucosyl phosphate
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
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