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Reference on EC 2.4.1.144 - beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Schachter, H.; Brockhausen, I.; Hull, E.
High-performance liquid chromatography assays for N-acetylglucosaminyltransferases involved in N- and O-glycan synthesis
Methods Enzymol.
179
351-397
1989
Gallus gallus, Cricetulus griseus, Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Taniguchi, N.; Nishikawa, A.; Fujii, S.; Gu, J.
Glycosyltransferase assays using pyridylaminated acceptors: N-acetylglucosaminyltransferase III, IV, and V
Methods Enzymol.
179
397-408
1989
Rattus norvegicus
Manually annotated by BRENDA team
Oguri, S.; Minowa, M.T.; Ihara, Y.; Taniguchi, N.; Ikenaga, H.; Takeuchi, M.
Purification and characterization of UDP-N-acetylglucosamine: alpha1,3-D-mannoside beta1,4-N-acetylglucosaminyltransferase (N-acetylglucosaminyltransferase-IV) from bovine small intestine
J. Biol. Chem.
272
22721-22727
1997
Homo sapiens
Automatic Mining of ENzyme DAta
Takamatsu, S.; Oguri, S.; Minowa, M.T.; Yoshida, A.; Nakamura, K.; Takeuchi, M.; Kobata, A.
Unusually high expression of N-acetylglucosaminyltransferase-IVa in human choriocarcinoma cell lines: a possible enzymatic basis of the formation of abnormal biantennary sugar chain
Cancer Res.
59
3949-3953
1999
Homo sapiens
Automatic Mining of ENzyme DAta
Narasimhan, S.
Control of glycoprotein synthesis. UDP-GlcNAc:glycopeptide beta 4-N-acetylglucosaminyltransferase III, an enzyme in hen oviduct which adds GlcNAc in beta 1-4 linkage to the beta-linked mannose of the trimannosyl core of N-glycosyl oligosaccharides
J. Biol. Chem.
257
10235-10242
1982
Gallus gallus
Manually annotated by BRENDA team
Nishikawa, A.; Ihara, Y.; Hatakeyama, M.; Kangawa, K.; Taniguchi, N.
Purification, cDNA cloning, and expression of UDP-N-acetylglucosamine: beta-D-mannoside beta-1,4N-acetylglucosaminyltransferase III from rat kidney
J. Biol. Chem.
267
18199-18204
1992
BRENDA: Cricetulus griseus, Homo sapiens, Rattus norvegicus (Q02527)
Textmining: Rattus
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
Miyoshi, E.; Nishikawa, A.; Ihara, Y.; Hayashi, N.; Fusamoto, H.; Kamada, T.; Taniguchi, N.
Selective suppression of N-acetylglucosaminyltransferase III activity in a human hepatoblastoma cell line transfected with hepatitis B virus
Cancer Res.
54
1854-1858
1994
BRENDA: Homo sapiens
Textmining: Hepatitis B virus
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
Yoshimura, M.; Nishikawa, A.; Ihara, Y.; Nishiura, T.; Nakao, H.; Kanayama, Y.; Matuzawa, Y.; Taniguchi, N.
High expression of UDP-N-acetylglucosamine:beta-D mannoside beta-1,4-N-acetylglucosaminyltransferase III (GnT-III) in chronic myelogenous leukemia in blast crisis
Int. J. Cancer
60
443-449
1995
Homo sapiens
Manually annotated by BRENDA team
Nagai, K.; Ihara, Y.; Wada, Y.; Taniguchi, N.
N-Glycosylation is requisite for the enzyme activity and Golgi retention of N-acetylglucosaminyltransferase III
Glycobiology
7
769-776
1997
BRENDA: Rattus norvegicus
Textmining: Rattus
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
Taniguchi, N.; Yoshimura, M.; Miyoshi, E.; Ihara, Y.; Nishikawa, A.; Kang, R.; Ikeda, Y.
Gene expression and regulation of N-acetylglucosaminyltransferases III and V in cancer tissues
Adv. Enzyme Regul.
38
223-232
1998
Homo sapiens, no activity in Mus musculus
Manually annotated by BRENDA team
Rudd, P.M.; Endo, T.; Colominas, C.; Groth, D.; Wheeler, S.F.; Harvey, D.J.; Wormald, M.R.; Serban, H.; Prusiner, S.B.; Kobata, A.; Dwek, R.A.
Glycosylation differences between the normal and pathogenic prion protein isoforms
Proc. Natl. Acad. Sci. USA
96
13044-13049
1999
BRENDA: Mesocricetus auratus
Textmining: prion
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
Shibukawa, Y.; Takahashi, M.; Laffont, I.; Honke, K.; Taniguchi, N.
Down-regulation of hydrogen peroxide-induced PKCdelta activation in N-acetylglucosaminyltransferase III-transfected HeLaS3 cells
J. Biol. Chem.
278
3197-3203
2003
Homo sapiens
Manually annotated by BRENDA team
Taniguchi, N.; Miyoshi, E.; Ko, J.H.; Ikeda, Y.; Ihara, Y.
Implication of N-acetylglucosaminyltransferases III and V in cancer: gene regulation and signaling mechanism
Biochim. Biophys. Acta
1455
287-300
1999
Gallus gallus, Homo sapiens, Mus musculus, Rattus norvegicus, Rattus norvegicus (Q02527)
Manually annotated by BRENDA team
Song, E.Y.; Kim, K.A.; Kim, Y.D.; Kwon, D.H.; Lee, H.S.; Kim, C.H.; Chung, T.W.; Byun, S.M.
A simplified procedure for the purification of human N-acetylglucosaminyltransferase-III from human hepatocellular carcinoma tissues
Biotechnol. Lett.
22
201-204
2000
Homo sapiens
-
Manually annotated by BRENDA team
Ikeda, Y.; Koyota, S.; Ihara, H.; Yamaguchi, Y.; Korekane, H.; Tsuda, T.; Sasai, K.; Taniguchi, N.
Kinetic basis for the donor nucleotide-sugar specificity of beta1,4-N-acetylglucosaminyltransferase III
J. Biochem.
128
609-619
2000
Rattus norvegicus
Manually annotated by BRENDA team
Guo, H.B.; Jiang, A.L.; Ju, T.Z.; Chen, H.L.
Opposing changes in N-acetylglucosaminyltransferase-V and -III during the cell cycle and all-trans retinoic acid treatment of hepatocarcinoma cell line
Biochim. Biophys. Acta
1495
297-307
2000
Homo sapiens
Manually annotated by BRENDA team
Song, E.Y.; Kang, S.K.; Lee, Y.C.; Park, Y.G.; Chung, T.H.; Kwon, D.H.; Byun, S.M.; Kim, C.H.
Expression of bisecting N-acetylglucosaminyltransferase-III in human hepatocarcinoma tissues, fetal liver tissues, and hepatoma cell lines of Hep3B and HepG2
Cancer Invest.
19
799-807
2001
Homo sapiens
Manually annotated by BRENDA team
Ikeda, Y.; Taniguchi, N.
Enzymatic properties and biological functions of beta1,4-N-acetylglucosaminyltransferase III
Trends Glycosci. Glycotechnol.
13
167-176
2001
Gallus gallus, Homo sapiens, Rattus norvegicus, Rattus norvegicus (Q02527)
-
Manually annotated by BRENDA team
Ihara, H.; Ikeda, Y.; Koyota, S.; Endo, T.; Honke, K.; Taniguchi, N.
A catalytically inactive beta1,4-N-acetylglucosaminyltransferase III (GnT-III) behaves as a dominant negative GnT-III inhibitor
Eur. J. Biochem.
269
193-201
2002
BRENDA: Homo sapiens, Rattus norvegicus
Textmining: Rattus
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
Takamatsu, S.; Inoue, N.; Katsumata, T.; Nakamura, K.; Fujibayashi, Y.; Takeuchi, M.
The relationship between the branch-forming glycosyltransferases and cell surface sugar chain structures
Biochemistry
44
6343-6349
2005
Homo sapiens
Manually annotated by BRENDA team
Gu, J.; Zhao, Y.; Isaji, T.; Shibukawa, Y.; Ihara, H.; Takahashi, M.; Ikeda, Y.; Miyoshi, E.; Honke, K.; Taniguchi, N.
beta1,4-N-Acetylglucosaminyltransferase III down-regulates neurite outgrowth induced by costimulation of epidermal growth factor and integrins through the Ras/ERK signaling pathway in PC12 cells
Glycobiology
14
177-186
2004
BRENDA: Rattus norvegicus
Textmining: Rattus
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
Song, E.Y.; Kim, K.S.; Kim, K.A.; Kim, Y.D.; Kwon, D.H.; Byun, S.M.; Kim, H.J.; Chung, T.W.; Choe, Y.K.; Chung, T.W.; Kim, C.H.
Determination of UDP-N-acetylglucosamine:beta-D-mannoside-1,4-N-acetylglucosaminyltransferase-III in patients sera with chronic hepatitis and liver cirrhosis using a monoclonal antibody
Glycoconj. J.
19
415-421
2003
Homo sapiens
Manually annotated by BRENDA team
Jin, X.L.; Liu, H.B.; Zhang, Y.; Wang, B.S.; Chen, H.L.
Alteration in N -acetylglucosaminyltransferase activities and glycan structure in tissue and bile glycoproteins from extrahepatic bile duct carcinoma
Glycoconj. J.
20
399-406
2004
Homo sapiens
Manually annotated by BRENDA team
Takamatsu, S.; Katsumata, T.; Inoue, N.; Watanabe, T.; Fujibayashi, Y.; Takeuchi, M.
Abnormal biantennary sugar chains are expressed in human chorionic gonadotropin produced in the choriocarcinoma cell line, JEG-3
Glycoconj. J.
20
473-481
2004
Homo sapiens
Manually annotated by BRENDA team
Sasai, K.; Ikeda, Y.; Ihara, H.; Honke, K.; Taniguchi, N.
Caveolin-1 regulates the functional localization of N-acetylglucosaminyltransferase III within the Golgi apparatus
J. Biol. Chem.
278
25295-25301
2003
Homo sapiens
Manually annotated by BRENDA team
Dawson, G.; Moskal, J.R.; Dawson, S.A.
Transfection of 2,6 and 2,3-sialyltransferase genes and GlcNAc-transferase genes into human glioma cell line U-373 MG affects glycoconjugate expression and enhances cell death
J. Neurochem.
89
1436-1444
2004
Homo sapiens
Automatic Mining of ENzyme DAta
Chung, T.W.; Kim, K.S.; Kim, C.H.
Reduction of the Gal-alpha1,3-Gal epitope of mouse endothelial cells by transfection with the N-acetylglucosaminyltransferase III gene
Mol. Cells
16
368-376
2003
BRENDA: Homo sapiens
Textmining: Mus musculus, Griffonia simplicifolia, Sus scrofa
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
Ferrara, C.; Bruenker, P.; Suter, T.; Moser, S.; Puentener, U.; Umana, P.
Modulation of therapeutic antibody effector functions by glycosylation engineering: influence of Golgi enzyme localization domain and co-expression of heterologous beta1,4-N-acetylglucosaminyltransferase III and Golgi alpha-mannosidase II
Biotechnol. Bioeng.
93
851-861
2006
Rattus norvegicus
Manually annotated by BRENDA team
Shigeta, M.; Shibukawa, Y.; Ihara, H.; Miyoshi, E.; Taniguchi, N.; Gu, J.
beta1,4-N-Acetylglucosaminyltransferase III potentiates beta1 integrin-mediated neuritogenesis induced by serum deprivation in Neuro2a cells
Glycobiology
16
564-571
2006
Rattus norvegicus
Manually annotated by BRENDA team
Rouwendal, G.J.; Wuhrer, M.; Florack, D.E.; Koeleman, C.A.; Deelder, A.M.; Bakker, H.; Stoopen, G.M.; van Die, I.; Helsper, J.P.; Hokke, C.H.; Bosch, D.
Efficient introduction of a bisecting GlcNAc residue in tobacco N-glycans by expression of the gene encoding human N-acetylglucosaminyltransferase III
Glycobiology
17
334-344
2007
BRENDA: Homo sapiens
Textmining: Nicotiana tabacum, plant
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
Iijima, J.; Zhao, Y.; Isaji, T.; Kameyama, A.; Nakaya, S.; Wang, X.; Ihara, H.; Cheng, X.; Nakagawa, T.; Miyoshi, E.; Kondo, A.; Narimatsu, H.; Taniguchi, N.; Gu, J.
Cell-cell interaction-dependent regulation of N-acetylglucosaminyltransferase III and the bisected N-glycans in GE11 epithelial cells. Involvement of E-cadherin-mediated cell adhesion
J. Biol. Chem.
281
13038-13046
2006
Mus musculus
Manually annotated by BRENDA team
Zhao, Y.; Nakagawa, T.; Itoh, S.; Inamori, K.; Isaji, T.; Kariya, Y.; Kondo, A.; Miyoshi, E.; Miyazaki, K.; Kawasaki, N.; Taniguchi, N.; Gu, J.
N-acetylglucosaminyltransferase III antagonizes the effect of N-acetylglucosaminyltransferase V on alpha3beta1 integrin-mediated cell migration
J. Biol. Chem.
281
32122-32130
2006
Homo sapiens
Manually annotated by BRENDA team
Takahagi, Y.; Fujimura, T.; Miyagawa, S.; Nagashima, H.; Shigehisa, T.; Shirakura, R.; Murakami, H.
Production of alpha 1,3-galactosyltransferase gene knockout pigs expressing both human decay-accelerating factor and N-acetylglucosaminyltransferase III
Mol. Reprod. Dev.
71
331-338
2005
BRENDA: Homo sapiens
Textmining: Suidae, Sus scrofa
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
Li, W.; Takahashi, M.; Shibukawa, Y.; Yokoe, S.; Gu, J.; Miyoshi, E.; Honke, K.; Ikeda, Y.; Taniguchi, N.
Introduction of bisecting GlcNAc in N-glycans of adenylyl cyclase III enhances its activity
Glycobiology
17
655-662
2007
BRENDA: Rattus norvegicus
Textmining: Mus musculus
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
Chakraborty, A.K.; Pawelek, J.
beta1,6-Branched oligosaccharides regulate melanin content and motility in macrophage-melanoma fusion hybrids
Melanoma Res.
17
9-16
2007
BRENDA: Mus musculus
Textmining: Homo sapiens
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
Frey, A.D.; Karg, S.R.; Kallio, P.T.
Expression of rat beta(1,4)-N-acetylglucosaminyltransferase III in Nicotiana tabacum remodels the plant-specific N-glycosylation
Plant Biotechnol. J.
7
33-48
2009
BRENDA: Rattus norvegicus
Textmining: Nicotiana tabacum, Rattus, Arabidopsis thaliana, Homo sapiens, Mammalia, plant
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
Akama, R.; Sato, Y.; Kariya, Y.; Isaji, T.; Fukuda, T.; Lu, L.; Taniguchi, N.; Ozawa, M.; Gu, J.
N-acetylglucosaminyltransferase III expression is regulated by cell-cell adhesion via the E-cadherin-catenin-actin complex
Proteomics
8
3221-3228
2008
Homo sapiens
Manually annotated by BRENDA team
Gu, J.; Isaji, T.; Sato, Y.; Kariya, Y.; Fukuda, T.
Importance of N-glycosylation on alpha5beta1 integrin for its biological functions
Biol. Pharm. Bull.
32
780-785
2009
Homo sapiens
Manually annotated by BRENDA team
Gu, J.; Taniguchi, N.
Potential of N-glycan in cell adhesion and migration as either a positive or negative regulator
Cell Adh. Migr.
2
243-245
2008
Homo sapiens
Manually annotated by BRENDA team
Okada, T.; Ihara, H.; Ito, R.; Taniguchi, N.; Ikeda, Y.
Bidirectional N-acetylglucosamine transfer mediated by beta-1,4-N-acetylglucosaminyltransferase III
Glycobiology
19
368-374
2009
Rattus norvegicus
Manually annotated by BRENDA team
Pinho, S.S.; Reis, C.A.; Paredes, J.; Magalhaes, A.M.; Ferreira, A.C.; Figueiredo, J.; Xiaogang, W.; Carneiro, F.; Gaertner, F.; Seruca, R.
The role of N-acetylglucosaminyltransferase III and V in the post-transcriptional modifications of E-cadherin
Hum. Mol. Genet.
18
2599-2608
2009
Homo sapiens
Manually annotated by BRENDA team
Kariya, Y.; Kato, R.; Itoh, S.; Fukuda, T.; Shibukawa, Y.; Sanzen, N.; Sekiguchi, K.; Wada, Y.; Kawasaki, N.; Gu, J.
N-Glycosylation of laminin-332 regulates its biological functions. A novel function of the bisecting GlcNAc
J. Biol. Chem.
283
33036-33045
2008
Homo sapiens
Manually annotated by BRENDA team
Sato, Y.; Isaji, T.; Tajiri, M.; Yoshida-Yamamoto, S.; Yoshinaka, T.; Somehara, T.; Fukuda, T.; Wada, Y.; Gu, J.
An N-glycosylation site on the beta-propeller domain of the integrin alpha5 subunit plays key roles in both its function and site-specific modification by beta1,4-N-acetylglucosaminyltransferase III
J. Biol. Chem.
284
11873-11881
2009
Homo sapiens
Manually annotated by BRENDA team
Karg, S.R.; Frey, A.D.; Kallio, P.T.
Reduction of N-linked xylose and fucose by expression of rat beta1,4-N-acetylglucosaminyltransferase III in tobacco BY-2 cells depends on Golgi enzyme localization domain and genetic elements used for expression
J. Biotechnol.
146
54-65
2010
BRENDA: Rattus norvegicus
Textmining: Nicotiana tabacum, Rattus, Arabidopsis thaliana, plant
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
Gu, J.; Sato, Y.; Kariya, Y.; Isaji, T.; Taniguchi, N.; Fukuda, T.
A mutual regulation between cell-cell adhesion and N-glycosylation: implication of the bisecting GlcNAc for biological functions
J. Proteome Res.
8
431-435
2009
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Pinho, S.S.; Figueiredo, J.; Cabral, J.; Carvalho, S.; Dourado, J.; Magalhaes, A.; Gaertner, F.; Mendonca, A.M.; Isaji, T.; Gu, J.; Carneiro, F.; Seruca, R.; Taniguchi, N.; Reis, C.A.
E-cadherin and adherens-junctions stability in gastric carcinoma: Functional implications of glycosyltransferases involving N-glycan branching biosynthesis, N-acetylglucosaminyltransferases III and V
Biochim. Biophys. Acta
1830
2690-2700
2012
Homo sapiens, Homo sapiens (Q09327)
Manually annotated by BRENDA team
Okada, T.; Ihara, H.; Ito, R.; Nakano, M.; Matsumoto, K.; Yamaguchi, Y.; Taniguchi, N.; Ikeda, Y.
N-Glycosylation engineering of lepidopteran insect cells by the introduction of the beta1,4-N-acetylglucosaminyltransferase III gene
Glycobiology
20
1147-1159
2010
BRENDA: Rattus norvegicus
Textmining: Spodoptera frugiperda, Rattus
Manually annotated by BRENDA teamAutomatic Mining of ENzyme DAta
Xu, Q.; Akama, R.; Isaji, T.; Lu, Y.; Hashimoto, H.; Kariya, Y.; Fukuda, T.; Du, Y.; Gu, J.
Wnt/beta-catenin signaling down-regulates N-acetylglucosaminyltransferase III expression: the implications of two mutually exclusive pathways for regulation
J. Biol. Chem.
286
4310-4318
2011
Homo sapiens
Manually annotated by BRENDA team
Xu, Q.; Isaji, T.; Lu, Y.; Gu, W.; Kondo, M.; Fukuda, T.; Du, Y.; Gu, J.
Roles of N-acetylglucosaminyltransferase III in epithelial-to-mesenchymal transition induced by transforming growth factor beta1 (TGF-beta1) in epithelial cell lines
J. Biol. Chem.
287
16563-16574
2012
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Reinke, S.; Bayer, M.; Berger, M.; Blanchard, V.; Hinderlich, S.
Analysis of cell surface N-glycosylation of the human embryonic kidney 293T cell line
J. Carbohydr. Chem.
30
218-232
2011
Homo sapiens
-
Manually annotated by BRENDA team
Pinho, S.S.; Oliveira, P.; Cabral, J.; Carvalho, S.; Huntsman, D.; Gaertner, F.; Seruca, R.; Reis, C.A.; Oliveira, C.
Loss and recovery of Mgat3 and GnT-III mediated E-cadherin N-glycosylation is a mechanism involved in epithelial-mesenchymal-epithelial transitions
PLoS ONE
7
e33191
2012
Homo sapiens
Manually annotated by BRENDA team
Bubka, M.; Link-Lenczowski, P.; Janik, M.; Pochec, E.; Litynska, A.
Overexpression of N-acetylglucosaminyltransferases III and V in human melanoma cells. Implications for MCAM N-glycosylation
Biochimie
103
37-49
2014
Homo sapiens (Q09327), Homo sapiens
Manually annotated by BRENDA team
Hanashima, S.; Korekane, H.; Taniguchi, N.; Yamaguchi, Y.
Synthesis of N-glycan units for assessment of substrate structural requirements of N-acetylglucosaminyltransferase III
Bioorg. Med. Chem. Lett.
24
4533-4537
2014
Homo sapiens (Q09327)
Manually annotated by BRENDA team
Lu, J.; Isaji, T.; Im, S.; Fukuda, T.; Kameyama, A.; Gu, J.
Expression of N-acetylglucosaminyltransferase III suppresses alpha2,3-sialylation, and its distinctive functions in cell migration are attributed to alpha2,6-sialylation levels
J. Biol. Chem.
291
5708-5720
2016
Homo sapiens (Q09327), Homo sapiens
Manually annotated by BRENDA team
Link-Lenczowski, P.; Bubka, M.; Balog, C.I.A.; Koeleman, C.A.M.; Butters, T.D.; Wuhrer, M.; Litynska, A.
The glycomic effect of N-acetylglucosaminyltransferase III overexpression in metastatic melanoma cells. GnT-III modifies highly branched N-glycans
Glycoconj. J.
35
217-231
2018
Homo sapiens (Q09327)
Manually annotated by BRENDA team
Allam, H.; Johnson, B.P.; Zhang, M.; Lu, Z.; Cannon, M.J.; Abbott, K.L.
The glycosyltransferase GnT-III activates Notch signaling and drives stem cell expansion to promote the growth and invasion of ovarian cancer
J. Biol. Chem.
292
16351-16359
2017
Homo sapiens (Q09327)
Manually annotated by BRENDA team
Deng, Q.; Yin, N.; Chen, Y.; Shan, N.; Liu, X.; Qi, H.
Downregulated N-acetylglucosaminyltransferase III is involved in attenuating trophoblast migration and invasion under hypoxia-reoxygenation condition
J. Matern. Fetal. Neonatal. Med.
32
2369-2375
2019
Homo sapiens (Q09327), Homo sapiens
Manually annotated by BRENDA team
Guo, JM; Zhang, XY; Chen, HL; Wang, GM; Zhang, YK
Structural alterations of sugar chains in urine fibronectin from bladder cancer patients and its enzymatic mechanism.
J Cancer Res Clin Oncol
127
512-9
2001
Homo sapiens
Automatic Mining of ENzyme DAta
Koyota, S; Ikeda, Y; Miyagawa, S; Ihara, H; Koma, M; Honke, K; Shirakura, R; Taniguchi, N
Down-regulation of the alpha-Gal epitope expression in N-glycans of swine endothelial cells by transfection with the N-acetylglucosaminyltransferase III gene. Modulation of the biosynthesis of terminal structures by a bisecting GlcNAc.
J Biol Chem
276
32867-74
2001
Sus scrofa
Automatic Mining of ENzyme DAta
Okamoto, Y; Ito, E; Akamatsu, N
UDP-N-acetylglucosamine-glycoprotein N-acetylglucosaminyltransferase in regenerating rat liver.
Biochim Biophys Acta
542
21-7
1978
Rattus
Automatic Mining of ENzyme DAta
Stanley, P; Narasimhan, S; Siminovitch, L; Schachter, H
Chinese hamster ovary cells selected for resistance to the cytotoxicity of phytohemagglutinin are deficient in a UDP-N-acetylglucosamine--glycoprotein N-acetylglucosaminyltransferase activity.
Proc Natl Acad Sci U S A
72
3323-7
1975
Cricetulus griseus, Phaseolus vulgaris
Automatic Mining of ENzyme DAta
Bhaumik, M; Seldin, MF; Stanley, P
Cloning and chromosomal mapping of the mouse Mgat3 gene encoding N-acetylglucosaminyltransferase III.
Gene
164
295-300
1995
Mus musculus, Homo sapiens, Cricetulus griseus, Rattus
Automatic Mining of ENzyme DAta
Priatel, JJ; Sarkar, M; Schachter, H; Marth, JD
Isolation, characterization and inactivation of the mouse Mgat3 gene: the bisecting N-acetylglucosamine in asparagine-linked oligosaccharides appears dispensable for viability and reproduction.
Glycobiology
7
45-56
1997
Homo sapiens, Mus musculus, Mus sp., Rattus, vertebrata
Automatic Mining of ENzyme DAta
Kurihara, T; Miyazawa, T; Miyagawa, S; Tomonaga, K; Hazama, K; Yamada, J; Shirakura, R; Matsuura, Y
Sensitivity to human serum of gammaretroviruses produced from pig endothelial cells transduced with glycosyltransferase genes.
Xenotransplantation
10
562-8
2003
Homo sapiens, Sus scrofa, murine leukemia virus
Automatic Mining of ENzyme DAta
Sharma, A; Okabe, J; Birch, P; McClellan, SB; Martin, MJ; Platt, JL; Logan, JS
Reduction in the level of Gal(alpha1,3)Gal in transgenic mice and pigs by the expression of an alpha(1,2)fucosyltransferase.
Proc Natl Acad Sci U S A
93
7190-5
1996
Suidae, Mus musculus, Primates, Sus scrofa
Automatic Mining of ENzyme DAta
A STUDY OF ENDOTHELIAL CELLS AND FIBROBLASTS FROM HOMOZYGOUS ALPHA-1,3GALACTOSYLTRANSFERASE GENE KNOCKOUT PIGS WITH DAF AND GnT-III.
Transplantation
82
1049
2006
Suidae
Automatic Mining of ENzyme DAta
Ishibashi, K; Nishikawa, A; Hayashi, N; Kasahara, A; Sato, N; Fujii, S; Kamada, T; Taniguchi, N
N-acetylglucosaminyltransferase III in human serum, and liver and hepatoma tissues: increased activity in liver cirrhosis and hepatoma patients.
Clin Chim Acta
185
325-32
1989
Homo sapiens
Automatic Mining of ENzyme DAta
Pascale, R; Narasimhan, S; Rajalakshmi, S
Expression of N-acetylglucosaminyltransferase III in hepatic nodules generated by different models of rat liver carcinogenesis.
Carcinogenesis
10
961-4
1989
insertion sequences, Rattus
Automatic Mining of ENzyme DAta
Koenderman, AH; Koppen, PL; Koeleman, CA; van den Eijnden, DH
N-acetylglucosaminyltransferase III, IV and V activities in Novikoff ascites tumour cells, mouse lymphoma cells and hen oviduct. Application of a sensitive and specific assay by use of high-performance liquid chromatography.
Eur J Biochem
181
651-5
1989
Mus musculus
Automatic Mining of ENzyme DAta
Narasimhan, S; Lee, JW; Cheung, RK; Gelfand, EW; Schachter, H
Beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase III activity in human B and T lymphocyte lines and in tonsillar B and T lymphocytes.
Biochem Cell Biol
66
889-900
1988
Homo sapiens, Human gammaherpesvirus 4
Automatic Mining of ENzyme DAta
Narasimhan, S; Schachter, H; Rajalakshmi, S
Expression of N-acetylglucosaminyltransferase III in hepatic nodules during rat liver carcinogenesis promoted by orotic acid.
J Biol Chem
263
1273-81
1988
Rattus, Homo sapiens
Automatic Mining of ENzyme DAta
Nishikawa, A; Fujii, S; Sugiyama, T; Taniguchi, N
A method for the determination of N-acetylglucosaminyltransferase III activity in rat tissues involving HPLC.
Anal Biochem
170
349-54
1988
Rattus
Automatic Mining of ENzyme DAta
Yoshimura, M; Ihara, Y; Taniguchi, N
Changes of beta-1,4-N-acetylglucosaminyltransferase III (GnT-III) in patients with leukaemia.
Glycoconj J
12
234-40
1995
Homo sapiens
Automatic Mining of ENzyme DAta
Miyoshi, E; Ihara, Y; Hayashi, N; Fusamoto, H; Kamada, T; Taniguchi, N
Transfection of N-acetylglucosaminyltransferase III gene suppresses expression of hepatitis B virus in a human hepatoma cell line, HB611.
J Biol Chem
270
28311-5
1995
Homo sapiens, Hepatitis B virus
Automatic Mining of ENzyme DAta
Yoshimura, M; Nishikawa, A; Ihara, Y; Taniguchi, S; Taniguchi, N
Suppression of lung metastasis of B16 mouse melanoma by N-acetylglucosaminyltransferase III gene transfection.
Proc Natl Acad Sci U S A
92
8754-8
1995
Mus musculus
Automatic Mining of ENzyme DAta
Yoshimura, M; Taniguchi, N
[Suppression of lung metastasis of B16 mouse melanoma cells by introduction of N-acetylglucosaminyltransferase III gene]
Nippon Rinsho
53
1786-90
1995
Mus musculus
Automatic Mining of ENzyme DAta
Miyoshi, E; Nishikawa, A; Ihara, Y; Gu, J; Sugiyama, T; Hayashi, N; Fusamoto, H; Kamada, T; Taniguchi, N
N-acetylglucosaminyltransferase III and V messenger RNA levels in LEC rats during hepatocarcinogenesis.
Cancer Res
53
3899-902
1993
Rattus, Cuniculus
Automatic Mining of ENzyme DAta
Ihara, Y; Nishikawa, A; Tohma, T; Soejima, H; Niikawa, N; Taniguchi, N
cDNA cloning, expression, and chromosomal localization of human N-acetylglucosaminyltransferase III (GnT-III).
J Biochem (Tokyo)
113
692-8
1993
Homo sapiens, Rattus
Automatic Mining of ENzyme DAta
Kim, YJ; Park, JH; Kim, KS; Chang, JE; Ko, JH; Kim, MH; Chung, DH; Chung, TW; Choe, IS; Lee, YC; Kim, CH
Sequence analysis of the 5'-flanking region of the gene encoding human N-acetylglucosaminyltransferase III.
Gene
170
281-3
1996
Homo sapiens, Mus musculus
Automatic Mining of ENzyme DAta
Koyama, N; Miyoshi, E; Ihara, Y; Kang, R; Nishikawa, A; Taniguchi, N
Human N-acetylglucosaminyltransferase III gene is transcribed from multiple promoters.
Eur J Biochem
238
853-61
1996
Homo sapiens
Automatic Mining of ENzyme DAta
Taniguchi, N; Yoshimura, M; Miyoshi, E; Ihara, Y; Nishikawa, A; Fujii, S
Remodeling of cell surface glycoproteins by N-acetylglucosaminyltransferase III gene transfection: modulation of metastatic potentials and down regulation of hepatitis B virus replication.
Glycobiology
6
691-4
1996
Hepatitis B virus
Automatic Mining of ENzyme DAta
Tanemura, M; Miyagawa, S; Ihara, Y; Nishikawa, A; Suzuki, M; Yamamura, K; Matsuda, H; Shirakura, R; Taniguchi, N
Suppression of the xenoantigen Gal alpha(1,3)Gal by N-acetylglucosaminyltransferase III (GnT-III) in transgenic mice.
Transplant Proc
29
895-6
0
Mus musculus
Automatic Mining of ENzyme DAta
Tanemura, M; Miyagawa, S; Ihara, Y; Matsuda, H; Shirakura, R; Taniguchi, N
Significant downregulation of the major swine xenoantigen by N-acetylglucosaminyltransferase III gene transfection.
Biochem Biophys Res Commun
235
359-64
1997
Sus scrofa, Griffonia simplicifolia, Homo sapiens
Automatic Mining of ENzyme DAta
Sburlati, AR; UmaƱa, P; Prati, EG; Bailey, JE
Synthesis of bisected glycoforms of recombinant IFN-beta by overexpression of beta-1,4-N-acetylglucosaminyltransferase III in Chinese hamster ovary cells.
Biotechnol Prog
14
189-92
0
Cricetulus griseus
Automatic Mining of ENzyme DAta
Yoshimura, M; Ihara, Y; Nishiura, T; Okajima, Y; Ogawa, M; Yoshida, H; Suzuki, M; Yamamura, K; Kanakura, Y; Matsuzawa, Y; Taniguchi, N
Bisecting GlcNAc structure is implicated in suppression of stroma-dependent haemopoiesis in transgenic mice expressing N-acetylglucosaminyltransferase III.
Biochem J
331 ( Pt 3)
733-42
1998
Mus musculus, Mus sp.
Automatic Mining of ENzyme DAta
Kang, R; Ikeda, Y; Miyoshi, E; Wang, W; Li, W; Ihara, Y; Sheng, Y; Taniguchi, N
Cell cycle-dependent regulation of N-acetylglucosaminyltransferase-III in a human colon cancer cell line, Colo201.
Arch Biochem Biophys
374
52-8
2000
Homo sapiens
Automatic Mining of ENzyme DAta
Yang, X; Bhaumik, M; Bhattacharyya, R; Gong, S; Rogler, CE; Stanley, P
New evidence for an extra-hepatic role of N-acetylglucosaminyltransferase III in the progression of diethylnitrosamine-induced liver tumors in mice.
Cancer Res
60
3313-9
2000
Mus sp.
Automatic Mining of ENzyme DAta
Miyagawa, S; Murakami, H; Murase, A; Nakai, R; Koma, M; Koyota, S; Matsunami, K; Takahagi, Y; Fujimura, T; Shigehisa, T; Nagashima, H; Shirakura, R; Taniguchi, N
Transgenic pigs with human N-acetylglucosaminyltransferase III.
Transplant Proc
33
742-3
0
Homo sapiens, Suidae
Automatic Mining of ENzyme DAta
Miyagawa, S; Murakami, H; Takahagi, Y; Nakai, R; Yamada, M; Murase, A; Koyota, S; Koma, M; Matsunami, K; Fukuta, D; Fujimura, T; Shigehisa, T; Okabe, M; Nagashima, H; Shirakura, R; Taniguchi, N
Remodeling of the major pig xenoantigen by N-acetylglucosaminyltransferase III in transgenic pig.
J Biol Chem
276
39310-9
2001
Sus scrofa, Macaca fascicularis, Homo sapiens, Suidae, Mus musculus, Mus sp., Metazoa
Automatic Mining of ENzyme DAta
Bhattacharyya, R; Bhaumik, M; Raju, TS; Stanley, P
Truncated, inactive N-acetylglucosaminyltransferase III (GlcNAc-TIII) induces neurological and other traits absent in mice that lack GlcNAc-TIII.
J Biol Chem
277
26300-9
2002
Mus sp., Cricetulus griseus, Mus musculus
Automatic Mining of ENzyme DAta
Ekuni, A; Miyoshi, E; Ko, JH; Noda, K; Kitada, T; Ihara, S; Endo, T; Hino, A; Honke, K; Taniguchi, N
A glycomic approach to hepatic tumors in N-acetylglucosaminyltransferase III (GnT-III) transgenic mice induced by diethylnitrosamine (DEN): identification of haptoglobin as a target molecule of GnT-III.
Free Radic Res
36
827-33
2002
Mus musculus, Mus sp.
Automatic Mining of ENzyme DAta
Takahagi, Y; Miyagawa, S; Murakami, H; Matsunami, K; Fujimura, T; Shigehisa, T; Shirakura, R
Transgenic pigs expressing both human decay-accelerating factor and N-acetylglucosaminyltransferase III.
Transplant Proc
35
516-7
2003
Homo sapiens, Suidae
Automatic Mining of ENzyme DAta
Fujita, T; Machida, K; Matsumoto, Y; Saito, T; Sato, N; Takahagi, Y; Murakami, H; Miyagawa, S; Shirakura, R; Taniguchi, N
Cynomolgus monkey did not hyperacutely reject skin xenograft of N-acetylglucosaminyltransferase III gene transgenic pig.
Transplant Proc
35
518
2003
Macaca fascicularis, Sus scrofa
Automatic Mining of ENzyme DAta
Lee, J; Park, SH; Stanley, P
Antibodies that recognize bisected complex N-glycans on cell surface glycoproteins can be made in mice lacking N-acetylglucosaminyltransferase III.
Glycoconj J
19
211-9
2002
Mus sp., Cricetulus griseus, Mus musculus
Automatic Mining of ENzyme DAta
Yang, X; Tang, J; Rogler, CE; Stanley, P
Reduced hepatocyte proliferation is the basis of retarded liver tumor progression and liver regeneration in mice lacking N-acetylglucosaminyltransferase III.
Cancer Res
63
7753-9
2003
Mus sp., Mus musculus
Automatic Mining of ENzyme DAta
Chung, TW; Kim, KS; Kang, SK; Lee, JW; Song, EY; Chung, TH; Yeom, YI; Kim, CH
Remodeling of the major mouse xenoantigen, Galalpha1-3Galbeta1-4GlcNAc-R, by N-acetylglucosaminyltransferase-III.
Mol Cells
16
343-53
2003
Mus musculus, Homo sapiens, Mus sp.
Automatic Mining of ENzyme DAta
Kang, SK; Chung, TW; Lee, JY; Lee, YC; Morton, RE; Kim, CH
The hepatitis B virus X protein inhibits secretion of apolipoprotein B by enhancing the expression of N-acetylglucosaminyltransferase III.
J Biol Chem
279
28106-12
2004
Hepatitis B virus
Automatic Mining of ENzyme DAta
Lee, J; Song, EY; Chung, TW; Kang, SK; Kim, KS; Chung, TH; Yeom, YI; Kim, CH
Hyperexpression of N-acetylglucosaminyltransferase-III in liver tissues of transgenic mice causes fatty body and obesity through severe accumulation of Apo A-I and Apo B.
Arch Biochem Biophys
426
18-31
2004
Mus musculus, Homo sapiens, Mus sp., animal
Automatic Mining of ENzyme DAta
Fujita, T; Miyagawa, S; Ezoe, K; Saito, T; Sato, N; Takahagi, Y; Murakami, H; Matsunami, K; Shirakura, R; Taniguchi, N
Skin graft of double transgenic pigs of N-acetylglucosaminyltransferase III (GnT-III) and DAF (CD55) genes survived in cynomolgus monkey for 31 days.
Transpl Immunol
13
259-64
2004
Macaca fascicularis, Suidae, Homo sapiens, Sus scrofa, Platyrrhini, Rattus
Automatic Mining of ENzyme DAta
Shim, JK; Lee, YC; Chung, TH; Kim, CH
Elevated expression of bisecting N-acetylglucosaminyltransferase-III gene in a human fetal hepatocyte cell line by hepatitis B virus.
J Gastroenterol Hepatol
19
1374-87
2004
Homo sapiens, Hepatitis B virus, Indicator
Automatic Mining of ENzyme DAta
Fujimura, T; Kurome, M; Murakami, H; Takahagi, Y; Matsunami, K; Shimanuki, S; Suzuki, K; Miyagawa, S; Shirakura, R; Shigehisa, T; Nagashima, H
Cloning of the transgenic pigs expressing human decay accelerating factor and N-acetylglucosaminyltransferase III.
Cloning Stem Cells
6
294-301
2004
Homo sapiens, Suidae, Sus scrofa, Metazoa
Automatic Mining of ENzyme DAta
Komoda, H; Miyagawa, S; Omori, T; Takahagi, Y; Murakami, H; Shigehisa, T; Ito, T; Matsuda, H; Shirakura, R
Survival of adult islet grafts from transgenic pigs with N-acetylglucosaminyltransferase-III (GnT-III) in cynomolgus monkeys.
Xenotransplantation
12
209-16
2005
Homo sapiens, Macaca fascicularis, Platyrrhini, Suidae, Sus scrofa
Automatic Mining of ENzyme DAta
Deng, Q; Liu, X; Yang, Z; Xie, L
Expression of N-Acetylglucosaminyltransferase III Promotes Trophoblast Invasion and Migration in Early Human Placenta.
Reprod Sci
1933719118765967
2018
Homo sapiens
Automatic Mining of ENzyme DAta
Guo, HB; Liu, F; Chen, HL
Increased susceptibility to apoptosis of human hepatocarcinoma cells transfected with antisense N-acetylglucosaminyltransferase V cDNA.
Biochem Biophys Res Commun
264
509-17
1999
Homo sapiens
Automatic Mining of ENzyme DAta
Nakagawa, T; Miyoshi, E; Yakushijin, T; Hiramatsu, N; Igura, T; Hayashi, N; Taniguchi, N; Kondo, A
Glycomic analysis of alpha-fetoprotein L3 in hepatoma cell lines and hepatocellular carcinoma patients.
J Proteome Res
7
2222-33
2008
Homo sapiens, Lens culinaris
Automatic Mining of ENzyme DAta
Sultan, AS; Miyoshi, E; Ihara, Y; Nishikawa, A; Tsukada, Y; Taniguchi, N
Bisecting GlcNAc structures act as negative sorting signals for cell surface glycoproteins in forskolin-treated rat hepatoma cells.
J Biol Chem
272
2866-72
1997
Rattus
Automatic Mining of ENzyme DAta
Ezzelarab, M; Cooper, DK
Reducing Gal expression on the pig organ - a retrospective review.
Xenotransplantation
12
278-85
2005
insertion sequences
Automatic Mining of ENzyme DAta
Miyagawa, S; Takeishi, S; Yamamoto, A; Ikeda, K; Matsunari, H; Yamada, M; Okabe, M; Miyoshi, E; Fukuzawa, M; Nagashima, H
Survey of glycoantigens in cells from alpha1-3galactosyltransferase knockout pig using a lectin microarray.
Xenotransplantation
17
61-70
2010
Homo sapiens, Suidae
Automatic Mining of ENzyme DAta
Kwon, DN; Song, H; Park, JY; Lee, SY; Cho, SK; Kang, SJ; Jang, JS; Seo, HG; Kim, JH
Dynamic Control of Oligosaccharide Modification in the Mammary Gland: Linking Recombinant Human Erythropoietin Functional Analysis of Transgenic Mouse Milk-Derived hEPO.
Transgenic Res
15
37-55
2006
Mus musculus, Cricetulus griseus
Automatic Mining of ENzyme DAta
Zhang, M; Wang, M; Gao, R; Liu, X; Chen, X; Geng, Y; Ding, Y; Wang, Y; He, J
Altered ?1,6-GlcNAc and bisecting GlcNAc-branched N-glycan on integrin ?1 are associated with early spontaneous miscarriage in humans.
Hum Reprod
30
2064-75
2015
Homo sapiens
Automatic Mining of ENzyme DAta
Stanley, P
Biological consequences of overexpressing or eliminating N-acetylglucosaminyltransferase-TIII in the mouse.
Biochim Biophys Acta
1573
363-8
2002
Homo sapiens, Mus musculus, Rodentia, Mus sp.
Automatic Mining of ENzyme DAta
Fiala, M; Liu, PT; Espinosa-Jeffrey, A; Rosenthal, MJ; Bernard, G; Ringman, JM; Sayre, J; Zhang, L; Zaghi, J; Dejbakhsh, S; Chiang, B; Hui, J; Mahanian, M; Baghaee, A; Hong, P; Cashman, J
Innate immunity and transcription of MGAT-III and Toll-like receptors in Alzheimer's disease patients are improved by bisdemethoxycurcumin.
Proc Natl Acad Sci U S A
104
12849-54
2007
Homo sapiens
Automatic Mining of ENzyme DAta
Ohkawa, Y; Kizuka, Y; Takata, M; Nakano, M; Ito, E; Mishra, SK; Akatsuka, H; Harada, Y; Taniguchi, N
Peptide Sequence Mapping around Bisecting GlcNAc-Bearing N-Glycans in Mouse Brain.
Int J Mol Sci
22
2021
Mus musculus, Mus sp., Mammalia
Automatic Mining of ENzyme DAta
Priyambada, SA; Misaki, R; Okamoto, T; Okamoto, Y; Ohashi, T; Ueda, K; Matsuura, Y; Fujiyama, K
Cell surface N-glycan alteration in HepAD38 cell lines expressing Hepatitis B virus.
Virus Res
238
101-109
2017
Hepatitis B virus
Automatic Mining of ENzyme DAta
UmaƱa, P; Jean-Mairet, J; Bailey, JE
Tetracycline-regulated overexpression of glycosyltransferases in Chinese hamster ovary cells.
Biotechnol Bioeng
65
542-9
1999
Cricetulus griseus
Automatic Mining of ENzyme DAta
Nishikawa, A; Gu, J; Fujii, S; Taniguchi, N
Determination of N-acetylglucosaminyltransferases III, IV and V in normal and hepatoma tissues of rats.
Biochim Biophys Acta
1035
313-8
1990
Rattus
Automatic Mining of ENzyme DAta
Fukuta, K; Abe, R; Yokomatsu, T; Kono, N; Nagatomi, Y; Asanagi, M; Shimazaki, Y; Makino, T
Comparative study of the N-glycans of human monoclonal immunoglobulins M produced by hybridoma and parental cells.
Arch Biochem Biophys
378
142-50
2000
Homo sapiens, Human gammaherpesvirus 4
Automatic Mining of ENzyme DAta
Stanta, JL; Saldova, R; Struwe, WB; Byrne, JC; Leweke, FM; Rothermund, M; Rahmoune, H; Levin, Y; Guest, PC; Bahn, S; Rudd, PM
Identification of N-glycosylation changes in the CSF and serum in patients with schizophrenia.
J Proteome Res
9
4476-89
2010
Homo sapiens
Automatic Mining of ENzyme DAta
Hyuga, M; Hyuga, S; Kawasaki, N; Ohta, M; Itoh, S; Niimi, S; Kawanishi, T; Hayakawa, T
Enhancement of hepatocyte growth factor-induced cell scattering in N-acetylglucosaminyltransferase III-transfected HepG2 cells.
Biol Pharm Bull
27
781-5
2004
Homo sapiens
Automatic Mining of ENzyme DAta
Klasi?, M; Markulin, D; Vojta, A; Samaržija, I; Biruš, I; Dobrini?, P; Ventham, NT; Trbojevi?-Akma?i?, I; Šimurina, M; Štambuk, J; Razdorov, G; Kennedy, NA; Satsangi, J; Dias, AM; Pinho, S; Annese, V; Latiano, A; D'Inca, R; , ; Lauc, G; Zoldoš, V
Promoter methylation of the MGAT3 and BACH2 genes correlates with the composition of the immunoglobulin G glycome in inflammatory bowel disease.
Clin Epigenetics
10
75
2018
Homo sapiens
Automatic Mining of ENzyme DAta
Rebbaa, A; Yamamoto, H; Saito, T; Meuillet, E; Kim, P; Kersey, DS; Bremer, EG; Taniguchi, N; Moskal, JR
Gene transfection-mediated overexpression of beta1,4-N-acetylglucosamine bisecting oligosaccharides in glioma cell line U373 MG inhibits epidermal growth factor receptor function.
J Biol Chem
272
9275-9
1997
Phaseolus vulgaris
Automatic Mining of ENzyme DAta
Nakao, H; Nishikawa, A; Karasuno, T; Nishiura, T; Iida, M; Kanayama, Y; Yonezawa, T; Tarui, S; Taniguchi, N
Modulation of N-acetylglucosaminyltransferase III, IV and V activities and alteration of the surface oligosaccharide structure of a myeloma cell line by interleukin 6.
Biochem Biophys Res Commun
172
1260-6
1990
Datura stramonium
Automatic Mining of ENzyme DAta
Nishikawa, A; Fujii, S; Sugiyama, T; Hayashi, N; Taniguchi, N
High expression of an N-acetylglucosaminyltransferase III in 3'-methyl DAB-induced hepatoma and ascites hepatoma.
Biochem Biophys Res Commun
152
107-12
1988
Rattus
Automatic Mining of ENzyme DAta
Khan, SH; Compston, CA; Palcic, MM; Hindsgaul, O
Synthesis of a di-O-methylated pentasaccharide for use in the assay of N-acetylglucosaminyltransferase III activity.
Carbohydr Res
262
283-95
1994
Rattus
Automatic Mining of ENzyme DAta
Ihara, Y; Sakamoto, Y; Mihara, M; Shimizu, K; Taniguchi, N
Overexpression of N-acetylglucosaminyltransferase III disrupts the tyrosine phosphorylation of Trk with resultant signaling dysfunction in PC12 cells treated with nerve growth factor.
J Biol Chem
272
9629-34
1997
Rattus
Automatic Mining of ENzyme DAta
Sheng, Y; Yoshimura, M; Inoue, S; Oritani, K; Nishiura, T; Yoshida, H; Ogawa, M; Okajima, Y; Matsuzawa, Y; Taniguchi, N
Remodeling of glycoconjugates on CD44 enhances cell adhesion to hyaluronate, tumor growth and metastasis in B16 melanoma cells expressing beta1,4-N-acetylglucosaminyltransferase III.
Int J Cancer
73
850-8
1997
Mus musculus, Mus sp.
Automatic Mining of ENzyme DAta
Ihara, Y; Yoshimura, M; Miyoshi, E; Nishikawa, A; Sultan, AS; Toyosawa, S; Ohnishi, A; Suzuki, M; Yamamura, K; Ijuhin, N; Taniguchi, N
Ectopic expression of N-acetylglucosaminyltransferase III in transgenic hepatocytes disrupts apolipoprotein B secretion and induces aberrant cellular morphology with lipid storage.
Proc Natl Acad Sci U S A
95
2526-30
1998
Mus musculus, Mus sp.
Automatic Mining of ENzyme DAta
Mori, S; Aoyagi, Y; Yanagi, M; Suzuki, Y; Asakura, H
Serum N-acetylglucosaminyltransferase III activities in hepatocellular carcinoma.
J Gastroenterol Hepatol
13
610-9
1998
Homo sapiens
Automatic Mining of ENzyme DAta
Davies, J; Jiang, L; Pan, LZ; LaBarre, MJ; Anderson, D; Reff, M
Expression of GnTIII in a recombinant anti-CD20 CHO production cell line: Expression of antibodies with altered glycoforms leads to an increase in ADCC through higher affinity for FC gamma RIII.
Biotechnol Bioeng
74
288-94
2001
Cricetulus griseus, Rattus
Automatic Mining of ENzyme DAta
Kurimoto, A; Kitazume, S; Kizuka, Y; Nakajima, K; Oka, R; Fujinawa, R; Korekane, H; Yamaguchi, Y; Wada, Y; Taniguchi, N
The absence of core fucose upregulates GnT-III and Wnt target genes: a possible mechanism for an adaptive response in terms of glycan function.
J Biol Chem
2014
Mus musculus, Mus sp.
Automatic Mining of ENzyme DAta
Wang, Y; Chen, S; Xu, Z; Chen, S; Yao, W; Gao, X
GLP-1 receptor agonists downregulate aberrant GnT-III expression in Alzheimer's disease models through the Akt/GSK-3?/?-catenin signaling.
Neuropharmacology
131
190-199
2018
Homo sapiens, Mus sp.
Automatic Mining of ENzyme DAta
da Silva Filho, AF; Vieira-de-Mello, GS; Dos Santos, PB; de Melo Rźgo, MJB; Ribeiro-Silva, A; Beltrćo, EIC
N-Acetylglucosaminyltransferase III (GnT-III) but not N-Acetylgalactosaminyltransferase-6 and 8 are Differentially Expressed in Invasive and In Situ Ductal Carcinoma of the Breast.
Pathol Oncol Res
2019
Arachis hypogaea, Phaseolus, Triticum aestivum, Homo sapiens
Automatic Mining of ENzyme DAta
Pan, K; Chen, S; Wang, Y; Yao, W; Gao, X
MicroRNA-23b attenuates tau pathology and inhibits oxidative stress by targeting GnT-III in Alzheimer's disease.
Neuropharmacology
196
108671
2021
Mus sp.
Automatic Mining of ENzyme DAta
Poche?, E; Rydlewska, M; Przyby?o, M; Lity?ska, A
Diverse expression of N-acetylglucosaminyltransferase V and complex-type ?1,6-branched N-glycans in uveal and cutaneous melanoma cells.
Acta Biochim Pol
62
323-8
2015
Transformation
Automatic Mining of ENzyme DAta
Kizuka, Y; Kitazume, S; Fujinawa, R; Saito, T; Iwata, N; Saido, TC; Nakano, M; Yamaguchi, Y; Hashimoto, Y; Staufenbiel, M; Hatsuta, H; Murayama, S; Manya, H; Endo, T; Taniguchi, N
An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer's disease.
EMBO Mol Med
7
175-89
2015
Mus sp., Homo sapiens
Automatic Mining of ENzyme DAta
Kizuka, Y; Nakano, M; Kitazume, S; Saito, T; Saido, TC; Taniguchi, N
Bisecting GlcNAc modification stabilizes BACE1 protein under oxidative stress conditions.
Biochem J
473
21-30
2016
Mus musculus
Automatic Mining of ENzyme DAta
Miyoshi, E; Ihara, Y; Nishikawa, A; Saito, H; Uozumi, N; Hayashi, N; Fusamoto, H; Kamada, T; Taniguchi, N
Gene expression of N-acetylglucosaminyltransferases III and V: a possible implication for liver regeneration.
Hepatology
22
1847-55
1995
Rattus
Automatic Mining of ENzyme DAta
Yoshimura, M; Ihara, Y; Ohnishi, A; Ijuhin, N; Nishiura, T; Kanakura, Y; Matsuzawa, Y; Taniguchi, N
Bisecting N-acetylglucosamine on K562 cells suppresses natural killer cytotoxicity and promotes spleen colonization.
Cancer Res
56
412-8
1996
Mus musculus
Automatic Mining of ENzyme DAta
Yoshimura, M; Ihara, Y; Matsuzawa, Y; Taniguchi, N
Aberrant glycosylation of E-cadherin enhances cell-cell binding to suppress metastasis.
J Biol Chem
271
13811-5
1996
Mus musculus
Automatic Mining of ENzyme DAta
Stanley, P; Sundaram, S; Tang, J; Shi, S
Molecular analysis of three gain-of-function CHO mutants that add the bisecting GlcNAc to N-glycans.
Glycobiology
15
43-53
2005
Cricetulus griseus, Homo sapiens, Mus musculus
Automatic Mining of ENzyme DAta
Allam, H; Aoki, K; Benigno, BB; McDonald, JF; Mackintosh, SG; Tiemeyer, M; Abbott, KL
Glycomic analysis of membrane glycoproteins with bisecting glycosylation from ovarian cancer tissues reveals novel structures and functions.
J Proteome Res
14
434-46
2015
Homo sapiens
Automatic Mining of ENzyme DAta
Zhang, W; Betel, D; Schachter, H
Cloning and expression of a novel UDP-GlcNAc:alpha-D-mannoside beta1,2-N-acetylglucosaminyltransferase homologous to UDP-GlcNAc:alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I.
Biochem J
361
153-62
2002
Homo sapiens
Automatic Mining of ENzyme DAta
Stanley, P; Sundaram, S; Sallustio, S
A subclass of cell surface carbohydrates revealed by a CHO mutant with two glycosylation mutations.
Glycobiology
1
307-14
1991
Cricetulus griseus, vesicular stomatitis virus
Automatic Mining of ENzyme DAta
UmaƱa, P; Jean-Mairet, J; Moudry, R; Amstutz, H; Bailey, JE
Engineered glycoforms of an antineuroblastoma IgG1 with optimized antibody-dependent cellular cytotoxic activity.
Nat Biotechnol
17
176-80
1999
Cricetulus griseus
Automatic Mining of ENzyme DAta
Hashii, N; Kawasaki, N; Itoh, S; Hyuga, M; Kawanishi, T; Hayakawa, T
Glycomic/glycoproteomic analysis by liquid chromatography/mass spectrometry: analysis of glycan structural alteration in cells.
Proteomics
5
4665-72
2005
Cricetulus griseus
Automatic Mining of ENzyme DAta
Akasaka-Manya, K; Manya, H; Sakurai, Y; Wojczyk, BS; Kozutsumi, Y; Saito, Y; Taniguchi, N; Murayama, S; Spitalnik, SL; Endo, T
Protective effect of N-glycan bisecting GlcNAc residues on {beta}-amyloid production in Alzheimer's disease.
Glycobiology
2009
Homo sapiens, Mus musculus
Automatic Mining of ENzyme DAta
Mo, D; Costa, SA; Ihrke, G; Youker, RT; Pastor-Soler, N; Hughey, RP; Weisz, OA
Sialylation of N-linked glycans mediates apical delivery of endolyn in MDCK cells via a galectin-9-dependent mechanism.
Mol Biol Cell
23
3636-46
2012
Canis lupus familiaris, Rattus
Automatic Mining of ENzyme DAta
Fukuta, K; Abe, R; Yokomatsu, T; Omae, F; Asanagi, M; Makino, T
Control of bisecting GlcNAc addition to N-linked sugar chains.
J Biol Chem
275
23456-61
2000
Homo sapiens
Automatic Mining of ENzyme DAta
Kitada, T; Miyoshi, E; Noda, K; Higashiyama, S; Ihara, H; Matsuura, N; Hayashi, N; Kawata, S; Matsuzawa, Y; Taniguchi, N
The addition of bisecting N-acetylglucosamine residues to E-cadherin down-regulates the tyrosine phosphorylation of beta-catenin.
J Biol Chem
276
475-80
2001
Mus musculus
Automatic Mining of ENzyme DAta
Ihara, Y; Nishikawa, A; Taniguchi, N
Effects of dibutyryl cAMP and bromodeoxyuridine on expression of N-acetylglucosaminyltransferases III and V in GOTO neuroblastoma cells.
Glycoconj J
12
787-94
1995
Homo sapiens
Automatic Mining of ENzyme DAta
Liu, AH; Liu, F; Li, Z; Gu, JX; Chen, HL
Alterations in glycosyltransferases during myeloid and monocytoid differentiation of HL-60 cells.
Cell Biol Int
22
545-50
1998
Homo sapiens
Automatic Mining of ENzyme DAta
Gao-Uozumi, CX; Uozumi, N; Miyoshi, E; Nagai, K; Ikeda, Y; Teshima, T; Noda, K; Shiba, T; Honke, K; Taniguchi, N
A novel carbohydrate binding activity of annexin V toward a bisecting N-acetylglucosamine.
Glycobiology
10
1209-16
2000
Sus scrofa
Automatic Mining of ENzyme DAta
Hodoniczky, J; Zheng, YZ; James, DC
Control of recombinant monoclonal antibody effector functions by Fc N-glycan remodeling in vitro.
Biotechnol Prog
21
1644-52
0
Rattus
Automatic Mining of ENzyme DAta
Barbin, K; Stieglmaier, J; Saul, D; Stieglmaier, K; Stockmeyer, B; Pfeiffer, M; Lang, P; Fey, GH
Influence of Variable N-Glycosylation on the Cytolytic Potential of Chimeric CD19 Antibodies.
J Immunother
29
122-133
0
Homo sapiens
Automatic Mining of ENzyme DAta
Fiala, M
Re-balancing of inflammation and abeta immunity as a therapeutic for Alzheimer's disease-view from the bedside.
CNS Neurol Disord Drug Targets
9
192-6
2010
Homo sapiens
Automatic Mining of ENzyme DAta
Khare, V; Lang, M; Dammann, K; Campregher, C; Lyakhovich, A; Gasche, C
Modulation of N-glycosylation by mesalamine facilitates membranous E-cadherin expression in colon epithelial cells.
Biochem Pharmacol
87
312-20
2014
Mus sp.
Automatic Mining of ENzyme DAta
Chaudhary, A; Bag, S; Mandal, M; Krishna Karri, SP; Barui, A; Rajput, M; Banerjee, P; Sheet, D; Chatterjee, J
Modulating prime molecular expressions and in vitro wound healing rate in keratinocyte (HaCaT) population under characteristic honey dilutions.
J Ethnopharmacol
166
211-9
2015
Homo sapiens, Argynnis pandora
Automatic Mining of ENzyme DAta
Nakano, M; Mishra, SK; Tokoro, Y; Sato, K; Nakajima, K; Yamaguchi, Y; Taniguchi, N; Kizuka, Y
Bisecting GlcNAc is a general suppressor of terminal modification of N-glycan.
Mol Cell Proteomics
2019
Mus sp.
Automatic Mining of ENzyme DAta