Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
acetyl-CoA + pantetheine
CoA + acetyl-S-pantetheine
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
butyryl-CoA + [acyl-carrier protein]
CoA + butyryl-[acyl-carrier protein]
hexanoyl-CoA + [acyl-carrier protein]
CoA + hexanoyl-[acyl-carrier protein]
octanoyl-CoA + [acyl-carrier protein]
CoA + octanoyl-[acyl-carrier protein]
propionyl-CoA + [acyl-carrier protein]
CoA + propionyl-[acyl-carrier protein]
additional information
?
-
acetyl-CoA + pantetheine
CoA + acetyl-S-pantetheine
-
dual specificity of a malonyl-CoA/acetyl-CoA:acyl carrier protein S-acyltransferase
-
r
acetyl-CoA + pantetheine
CoA + acetyl-S-pantetheine
-
dual specificity of a malonyl-CoA/acetyl-CoA:acyl carrier protein S-acyltransferase
-
r
acetyl-CoA + pantetheine
CoA + acetyl-S-pantetheine
-
octanoyl-S-pantetheine, decanoyl-S-pantetheine, and dodecanoyl-S-pantetheine can also serve as substrates for the backward reaction
-
r
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
-
-
?
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
-
-
?
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
-
-
?
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
part of non-associated fatty acid synthase system of plants and prokaryotes
-
?
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
-
-
?
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
equilibrium in forward direction
-
r
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
via acetyl-enzyme intermediate
-
r
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
via acetyl-enzyme intermediate
-
r
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
via acetyl-enzyme intermediate
-
r
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
pantetheine, not 2-mercaptoethanol can replace [acyl-carrier-protein]
-
r
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
acetyl-S-pantetheine can replace acetyl-CoA
-
?
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
acetyl-S-pantetheine can replace acetyl-CoA
-
r
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
via acetyl-enzyme intermediate
-
r
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
equilibrium in forward direction
-
r
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
via acetyl-enzyme intermediate
-
r
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
-
-
?
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
-
-
?
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
enzyme is component of fatty acid synthase complex II
-
?
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
enzyme is component of fatty acid synthase complex II
-
?
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
first step of fatty acid synthesis
-
?
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
-
-
?
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
enzyme is component of fatty acid synthase complex II
-
?
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
Persea sp.
-
-
-
?
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
-
-
?
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
-
-
-
?
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
dual specificity of a malonyl-CoA/acetyl-CoA:acyl carrier protein S-acyltransferase
-
?
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
dual specificity of a malonyl-CoA/acetyl-CoA:acyl carrier protein S-acyltransferase
-
?
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
-
-
?
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
-
-
?
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
increase in enzyme level in reconsituted FAS system enhances production of medium length fatty acids
-
?
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
rate-limiting step of fatty acid synthesis
-
?
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
rate-limiting step of fatty acid synthesis
-
?
acetyl-CoA + [acyl-carrier protein]
CoA + acetyl-[acyl-carrier protein]
-
specific for acetyl-CoA, utilizes [acyl-carrier-protein] of diverse origins with differing affinities
-
?
butyryl-CoA + [acyl-carrier protein]
CoA + butyryl-[acyl-carrier protein]
-
-
-
-
?
butyryl-CoA + [acyl-carrier protein]
CoA + butyryl-[acyl-carrier protein]
-
9.8% activity of that with acetyl-CoA
-
-
?
butyryl-CoA + [acyl-carrier protein]
CoA + butyryl-[acyl-carrier protein]
-
9.8% activity of that with acetyl-CoA
-
-
?
butyryl-CoA + [acyl-carrier protein]
CoA + butyryl-[acyl-carrier protein]
-
-
-
-
?
butyryl-CoA + [acyl-carrier protein]
CoA + butyryl-[acyl-carrier protein]
-
35% activity of that with acetyl-CoA
-
-
?
hexanoyl-CoA + [acyl-carrier protein]
CoA + hexanoyl-[acyl-carrier protein]
-
-
-
-
?
hexanoyl-CoA + [acyl-carrier protein]
CoA + hexanoyl-[acyl-carrier protein]
-
4.6% activity of that with acetyl-CoA
-
-
?
hexanoyl-CoA + [acyl-carrier protein]
CoA + hexanoyl-[acyl-carrier protein]
-
4.6% activity of that with acetyl-CoA
-
-
?
hexanoyl-CoA + [acyl-carrier protein]
CoA + hexanoyl-[acyl-carrier protein]
-
-
-
-
?
hexanoyl-CoA + [acyl-carrier protein]
CoA + hexanoyl-[acyl-carrier protein]
-
18% activity of that with acetyl-CoA
-
-
?
octanoyl-CoA + [acyl-carrier protein]
CoA + octanoyl-[acyl-carrier protein]
-
-
-
-
?
octanoyl-CoA + [acyl-carrier protein]
CoA + octanoyl-[acyl-carrier protein]
-
10.3% activity of that with acetyl-CoA
-
-
?
octanoyl-CoA + [acyl-carrier protein]
CoA + octanoyl-[acyl-carrier protein]
-
10.3% activity of that with acetyl-CoA
-
-
?
octanoyl-CoA + [acyl-carrier protein]
CoA + octanoyl-[acyl-carrier protein]
-
poor substrate
-
-
?
octanoyl-CoA + [acyl-carrier protein]
CoA + octanoyl-[acyl-carrier protein]
-
7% activity of that with acetyl-CoA
-
-
?
propionyl-CoA + [acyl-carrier protein]
CoA + propionyl-[acyl-carrier protein]
-
transacylation at 23.4% the rate of acetyl-CoA
-
-
?
propionyl-CoA + [acyl-carrier protein]
CoA + propionyl-[acyl-carrier protein]
-
transacylation at 23.4% the rate of acetyl-CoA
-
-
?
additional information
?
-
-
2-mercaptoethanol does not substitute for [acyl-carrier-protein]
-
-
?
additional information
?
-
-
no substrate: malonyl-CoA
-
-
?
additional information
?
-
-
no substrate: malonyl-CoA
-
-
?
additional information
?
-
-
in vertebrates, yeast and Mycobacteria acetyl transferase activity is a domain of the multifunctional polypeptide chains of fatty acid synthase EC 2.3.1.85 and EC 2.3.1.86
-
-
?
additional information
?
-
-
in vertebrates, yeast and Mycobacteria acetyl transferase activity is a domain of the multifunctional polypeptide chains of fatty acid synthase EC 2.3.1.85 and EC 2.3.1.86
-
-
?
additional information
?
-
-
2-mercaptoethanol does not substitute for [acyl-carrier-protein]
-
-
?
additional information
?
-
-
no substrate: malonyl-CoA
-
-
?
additional information
?
-
Persea sp.
-
no substrate: malonyl-CoA
-
-
?
additional information
?
-
-
enzyme is part of fatty acid synthetase complex, consisting of 2 subunits
-
-
?
additional information
?
-
-
no substrate: malonyl-CoA
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Shimakata, T.; Stumpf, P.K.
The procaryotic nature of the fatty acid synthetase of developing Carthamus tinctorius L. (Safflower) seeds
Arch. Biochem. Biophys.
217
144-154
1982
Carthamus tinctorius
brenda
Shimakata, T.; Stumpf, P.K.
The purification and function of acetyl coenzyme A:acyl carrier protein transacylase
J. Biol. Chem.
258
3592-3598
1983
Brassica juncea, Carthamus tinctorius, Cuphea lutea, Pisum sativum, Spinacia oleracea
brenda
Hendren, R.W.; Bloch, K.
Fatty acid synthetases from Euglena gracilis. Separation of component activities of the ACP-dependent fatty acid synthetase and partial purification of the beta-ketoacyl-ACP synthetase
J. Biol. Chem.
255
1504-1508
1980
Euglena gracilis, Euglena gracilis Z
brenda
Vagelos, R.P.
Acyl group transfer (acyl carrier protein)
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
8
155-199
1973
Escherichia coli
-
brenda
Prescott, D.J.; Vagelos, P.R.
Acyl carrier protein
Adv. Enzymol. Relat. Areas Mol. Biol.
36
269-311
1972
Escherichia coli
brenda
Williamson, I.P.; Wakil, S.J.
Studies on the mechanism of fatty acid synthesis. XVII. Preparation and general properties of acetyl coenzyme A and malonyl coenzyme A-acyl carrier protein transacylases
J. Biol. Chem.
241
2326-2332
1966
Escherichia coli, Escherichia coli E26
brenda
Shimakata, T.; Stumpf, P.K.
Purification of plant acetyl-CoA: acyl carrier protein transacylase
Methods Enzymol.
122
53-59
1986
Spinacia oleracea
brenda
Lowe, P.N.; Rhodes, S.
Purification and characterization of [acyl-carrier-protein] acetyltransferase from Escherichia coli
Biochem. J.
250
789-796
1988
Escherichia coli, Escherichia coli B / ATCC 11303
brenda
Alberts, A.W.; Majerus, P.W.; Vagelos, P.R.
Acetyl-CoA acyl carrier protein transacylase
Methods Enzymol.
14
50-53
1969
Escherichia coli, Escherichia coli B / ATCC 11303
-
brenda
Worsham, L.M.S.; Williams, S.G.; Ernst-Fonberg, M.L.
Early catalytic steps of Euglena gracilis chloroplast type II fatty acid synthase
Biochim. Biophys. Acta
1170
62-71
1993
Euglena gracilis
brenda
Gulliver, B.S.; Slabas, A.R.
Acetoacyl-acyl carrier protein synthase from avocado: its purification, characterization and clear resolution from acetyl CoA: ACP transacylase
Plant Mol. Biol.
25
179-191
1994
Persea sp.
brenda
Rangan, V.S.; Smith, S.
Alteration of the substrate specificity of the malonyl-CoA/acetyl-CoA:acyl carrier protein S-acyltransferase domain of the multifunctional fatty acid synthase by mutation of a single arginine residue
J. Biol. Chem.
272
11975-11978
1997
Rattus norvegicus
brenda
Rangan, V.S.; Joshi, A.K.; Smith, S.
Fatty acid synthase dimers containing catalytically active beta-ketoacyl synthase or malonyl/acetyltransferase domains in only one subunit can support fatty acid synthesis at the acyl carrier protein domains of both subunits
J. Biol. Chem.
273
34949-34953
1998
Rattus norvegicus
brenda
Lobo, S.; Florova, G.; Reynolds, K.A.
A Streptomyces collinus thiolase with novel acetyl-CoA:acyl carrier protein transacylase activity
Biochemistry
40
11955-11964
2001
Streptomyces collinus
brenda
Waters, N.C.; Kopydlowski, K.M.; Guszczynski, T.; Wei, L.; Sellers, P.; Ferlan, J.T.; Lee, P.J.; Li, Z.; Woodard, C.L.; Shallom, S.; Gardner, M.J.; Prigge, S.T.
Functional characterization of the acyl carrier protein (PfACP) and beta-ketoacyl ACP synthase III (PfKASIII) from Plasmodium falciparum
Mol. Biochem. Parasitol.
123
85-94
2002
Plasmodium falciparum
brenda