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acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
acyl-CoA + 1-acyl-sn-glycero-3-phosphoryldimethylethanolamine
CoA + 1,2-diacyl-sn-glycero-3-phosphoryldimethylethanolamine
-
preferred acyl acceptors in descending order: 1-acyl-sn-glycero-3-phosphocholine, 1-acyl-sn-glycero-3-phosphoryldimethylethanolamine, 1-acyl-sn-glycero-3-phosphorylmonomethylethanolamine, 1-acyl-sn-glycero-3-phosphorylethanolamine
-
?
acyl-CoA + 1-acyl-sn-glycero-3-phosphorylethanolamine
CoA + 1,2-diacyl-sn-glycero-3-phosphorylethanolamine
-
-
-
?
acyl-CoA + 1-acyl-sn-glycero-3-phosphorylmonomethylethanolamine
CoA + 1,2-diacyl-sn-glycero-3-phosphorylmonomethylethanolamine
-
-
-
?
acyl-CoA + 1-myristoyl-sn-glycero-3-phosphocholine
CoA + 1-myristoyl-2-acyl-sn-glycero-3-phosphocholine
-
preferred acyl acceptors: 1-myristyl-sn-glycero-3-phosphocholine, 1-stearyl-sn-glycero-3-phosphocholine, 1-oleoyl-sn-glycero-3-phosphocholine and 1-linoleoyl-sn-glycero-3-phosphocholine, very little activity with 1-decanoyl-sn-glycero-3-phosphocholine
-
?
acyl-CoA + 1-palmitoyl-sn-glycero-3-phosphocholine
CoA + 1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine
-
at 0.16 mM 1-palmitoyl-sn-glycero-3-phosphocholine is preferred 3.5fold over 1-stearoyl-sn-glycero-3-phosphocholine
-
r
arachidonoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1-acyl-2-arachidonoyl-sn-glycero-3-phosphocholine
arachidonoyl-CoA + 1-acyl-sn-glycero-3-phosphoethanolamine
CoA + 1-acyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine
arachidonoyl-CoA + 1-acyl-sn-glycero-3-phosphoinositol
CoA + 1-acyl-2-arachidonoyl-sn-glycero-3-phosphoinositol
arachidonoyl-CoA + 1-acyl-sn-glycero-3-phosphoserine
CoA + 1-acyl-2-arachidonoyl-sn-glycero-3-phosphoserine
linoleoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine
lysophosphatidylcholine + acyl-CoA
phosphatidylcholine + CoA
-
-
-
-
?
myristoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1-acyl-2-myristoyl-sn-glycero-3-phosphocholine
-
-
-
r
oleoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine
palmitoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1-acyl-2-palmitoyl-sn-glycero-3-phosphocholine
-
-
-
r
palmitoyl-CoA + 1-palmitoyl-sn-glycero-3-phosphocholine
CoA + 1,2-dipalmitoyl-sn-glycero-3-phosphocholine
palmitoyl-CoA + lysophosphatidylcholine
CoA + ?
-
-
-
-
?
stearoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1-acyl-2-stearoyl-sn-glycero-3-phosphocholine
-
-
-
-
r
additional information
?
-
acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
-
-
-
?
acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
-
-
r
acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
-
-
r
acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
-
-
r
acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
-
-
r
acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
-
-
r
acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
-
-
r
acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
-
-
r
acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
-
-
r
acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
-
-
r
acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
-
-
r
acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
-
-
r
acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
-
-
r
acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
-
-
r
acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
-
-
r
acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
-
-
r
acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
-
-
r
acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
specificity for acyl-CoA with unsaturated acyl groups, 1-palmitoyl-sn-glycero-3-phosphocholine is a better acceptor than 1-stearyl-sn-glycero-3-phosphocholine
-
r
acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
highest activity with polyunsaturated acyl-CoAs e.g. arachidonoyl-CoA, eicosatrienoyl-CoA and linoleoyl-CoA
-
r
acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
selectivity for polyunsaturated fatty acids, preferred acyl donors in descending order: arachidonyl-CoA, eicosapentaenoyl-CoA, docosahexaenoyl-CoA, in platelets, 1-acyl-sn-glycero-3-phosphocholine is a better acceptor than 1-acyl-sn-glycero-3-phosphorylethanolamine
-
r
acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
participates in deacylation/reacylation cycle of cell membranes
-
?
arachidonoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1-acyl-2-arachidonoyl-sn-glycero-3-phosphocholine
-
preferred acyl donors in descending order: arachidonoyl-CoA, linoleoyl-CoA, oleoyl-CoA, very little activity with palmitoyl-CoA, lauroyl-CoA, myristoyl-CoA, palmitolenoyl-CoA and stearoyl-CoA
-
r
arachidonoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1-acyl-2-arachidonoyl-sn-glycero-3-phosphocholine
-
preferred acyl donor
-
r
arachidonoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1-acyl-2-arachidonoyl-sn-glycero-3-phosphocholine
-
preferred acyl donors in descending order: arachidonoyl-CoA, linoleoyl-CoA, oleoyl-CoA, palmitoyl-CoA, stearoyl-CoA, 1-palmitoyl-sn-glycero-3-phosphocholine is preferred over 1-stearoyl-sn-glycero-3-phosphocholine as acceptor
-
?
arachidonoyl-CoA + 1-acyl-sn-glycero-3-phosphoethanolamine
CoA + 1-acyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine
-
-
-
?
arachidonoyl-CoA + 1-acyl-sn-glycero-3-phosphoethanolamine
CoA + 1-acyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine
-
57% and 6% of activity with 1-acyl-sn-glycero-3-phosphocholine in microsomes and phosphatidylcholine vesicles respectively
-
?
arachidonoyl-CoA + 1-acyl-sn-glycero-3-phosphoinositol
CoA + 1-acyl-2-arachidonoyl-sn-glycero-3-phosphoinositol
-
-
-
?
arachidonoyl-CoA + 1-acyl-sn-glycero-3-phosphoinositol
CoA + 1-acyl-2-arachidonoyl-sn-glycero-3-phosphoinositol
-
35% and 8% of activity with 1-acyl-sn-glycero-3-phosphocholine in microsomes and phosphatidylcholine vesicles respectively
-
?
arachidonoyl-CoA + 1-acyl-sn-glycero-3-phosphoserine
CoA + 1-acyl-2-arachidonoyl-sn-glycero-3-phosphoserine
-
-
-
-
?
arachidonoyl-CoA + 1-acyl-sn-glycero-3-phosphoserine
CoA + 1-acyl-2-arachidonoyl-sn-glycero-3-phosphoserine
-
99% and 22% of activity with 1-acyl-sn-glycero-3-phosphocholine in microsomes and phosphatidylcholine vesicles respectively
-
?
linoleoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine
-
-
-
-
?
linoleoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine
-
-
-
r
oleoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine
-
-
-
-
?
oleoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
CoA + 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine
-
-
-
r
palmitoyl-CoA + 1-palmitoyl-sn-glycero-3-phosphocholine
CoA + 1,2-dipalmitoyl-sn-glycero-3-phosphocholine
-
-
-
?
palmitoyl-CoA + 1-palmitoyl-sn-glycero-3-phosphocholine
CoA + 1,2-dipalmitoyl-sn-glycero-3-phosphocholine
quantification of palmitic acid by gas chromatography
-
-
?
additional information
?
-
the enzyme is involved in dipalmitoylphosphatidylcholine synthesis
-
-
?
additional information
?
-
substrate specificity, LPCAT prefers lysophosphatidylcholine as a substrate over lysophosphatidic acid, lysophosphatidylinositol, lysophosphatidylserine, lysophosphatidylethanolamine, or lysophosphatidylglycerol, and prefers palmitoyl-CoA to oleoyl-CoA as the acyl donor, the enzyme is involved in synthesis of membrane surfactant proteins and regulation of surfactant phospholipid biosynthesis
-
-
?
additional information
?
-
-
Golgi membrane tubule formation can result from increasing the content of lysophospholipids in membranes, either by stimulation of a phospholipase A2 or by inhibition of an lysophosphatidylcholine acyltransferase. The two opposing enzyme activities may help to coordinately regulate Golgi membrane shape and tubule formation
-
-
?
additional information
?
-
-
inhibition of Golgi complex-associated LPAT activity by the drug CI-976 stimulates Golgi tubule formation and subsequent redistribution of resident Golgi proteins to the endoplasmic reticulum, affecting secretory and endocytic membrane trafficking pathways, overview
-
-
?
additional information
?
-
a linear incorporation of labeled fatty acyl CoA into dipalmitoyl phosphatidylcholine (PC) indicates that lysophosphatidylcholine generated by Prdx6 PLA2 activity remains bound to the enzyme for the reacylation reaction
-
-
-
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1-acyl-sn-glycero-3-phosphocholine
-
high concentration, lung enzyme
2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)-dodecanamide
-
-
2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide
-
-
2-methoxy-5-methyl-3-tetradecanoyloxy-1,4-benzoquinone
-
potent inhibitor
3,4-dihydroxy-1,2-dimethoxy-5-methylbenzene
-
-
3-acetoxy-2-methoxy-5-methyl-1,4-benzoquinone
-
-
3-decanoyloxy-2-methoxy-5-methyl-1,4-benzoquinone
-
potent inhibitor
3-hexanoyloxy-2-methoxy-5-methyl-1,4-benzoquinone
-
-
Clofibric acid
-
inhibition of mitochondrial enzyme
Cyclic nucleotide phosphodiesterase inhibitors
-
liver and heart enzyme
-
dihydrofumigatin
-
i.e. 2-methoxy-1,3,4- trihydroxy-5-methylbenzene
fumigatin
-
i.e. 3-hydroxy-2-methoxy-5-methyl-1,4-benzoquinone
iodoacetate
-
liver enzyme
methanol
-
oleoyl-CoA as substrate
p-chloromercuribenzoate
-
partially restorable by dithiothreitol
p-chloromercuriphenyl sulfonic acid
Phosphorylhomocholine
-
-
photooxidized phospholipids
-
0.0001-0.01 mM photoxoidized phospholipids preincubated with 0.1 mg microsomal membranes, approx. 45% loss of initial activity
-
WY-14643
-
inhibition of mitochondrial enzyme
CI-976
-
complete inhibition at 0.05 mM, IC50: 0.015 mM, inhibition of Golgi complex-associated LPAT activity by the drug CI-976 stimulates Golgi tubule formation and subsequent redistribution of resident Golgi proteins to the endoplasmic reticulum, overview
CI-976
about 50% inhibition at 0.01 mM
N-ethylmaleimide
-
liver enzyme
N-ethylmaleimide
-
1 mM, 30% inhibition after 5 min, 95% inhibition after 45 min
p-chloromercuriphenyl sulfonic acid
-
liver enzyme
p-chloromercuriphenyl sulfonic acid
-
partially restorable by dithitothreitol
Triton X-100
-
0.1%
Triton X-100
-
0.5 mM, 40% inhibition, 2 mM, 92% inhibition
additional information
-
not inhibited by diisopropylfluorophosphate
-
additional information
-
not inhibited by IAA and DTNB
-
additional information
-
activity is reduced in rigid membranes obtained by incorporation of sphingomyelin and dipalmitoylphosphatidylcholine
-
additional information
-
not inhibited by 2-methoxy-5-methyl-1,3,4-triacetoxybenzene and 1,4-diacetoxy-2-methoxy-5-methyl-3-tetradecanoyloxybenzene
-
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Yamashita, S.; Hosaka, K.; Miki, Y.; Numa, S.
Glycerolipid acyltransferases from rat liver: 1-acylglycerophosphate acyltransferase, 1-acylglycerophosphorylcholine acyltransferase, and diacylglycerol acyltransferase
Methods Enzymol.
71
528-536
1981
Rattus norvegicus
brenda
Koshlukova, S.; Momchilova-Pankova, A.; Markovska, T.; Kumanov, K.
Phospholipid dependence of rat liver microsomal acyl:CoA synthetase and acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
J. Membr. Biol.
127
113-119
1992
Rattus norvegicus
brenda
Gavino, V.C.; Deamer, D.W.
Purification of acyl CoA:1-acyl-sn-glycero-3-phosphorylcholine acyltransferase
J. Bioenerg. Biomembr.
14
513-526
1982
Rattus norvegicus
brenda
Lands, W.E.M.; Hart, P.
Metabolism of glycerolipids. VI. Specificities of acyl-CoA: phospholipid acyltransferases
J. Biol. Chem.
240
1905-1911
1965
Bos taurus, Cavia porcellus, Mesocricetus auratus, Rattus norvegicus, Sus scrofa
brenda
Choy, P.C.; Tardi, P.G.; Mukherjee, J.J.
Lysophosphatidylcholine acyltransferase
Methods Enzymol.
209
80-86
1992
Bos taurus, Cavia porcellus, Oryctolagus cuniculus, Mammalia, Rattus norvegicus
brenda
Hill, E.E.; Lands, W.E.M.
Incorporation of long-chain and polyunsaturated acids into phosphatidate and phosphatidylcholine
Biochim. Biophys. Acta
152
645-648
1968
Cavia porcellus, Rattus norvegicus
brenda
Bouroudian, M.; Chautan, M.; Termine, E.; Lafont, H.; Nalbone, G.
Use of a silicic acid microcolumn to assay acyl-CoA: lysophosphatidylcholine acyltransferase
Biochim. Biophys. Acta
960
253-256
1988
Rattus norvegicus
brenda
Holub, B.J.; Piekarski, J.; Possmayer, F.
Relative suitability of 1-palmitoyl and 1-stearoyl homologues of 1-acyl-sn-glycerylphosphorylcholine and different acyl donors for phosphatidylcholine synthesis via acyl-CoA:1-acyl-sn-glycero-3-phosphorylcholine acyltransferase in rat lung microsomes
Can. J. Biochem.
58
434-439
1980
Rattus norvegicus
brenda
Van den Bosch, H.; Van Golde, L.M.G.; Eibl, H.; Van Deenen, L.L.M.
The acylation of 1-acylglycero-3-phosphorylcholines by rat-liver microsomes
Biochim. Biophys. Acta
144
613-623
1967
Rattus norvegicus
brenda
Yamashita, S.; Nakaya, N.; Miki, Y.; Numa, S.
Separation of 1-acylglycerolphosphate acyltransferase and 1-acylglycerolphosphorylcholine acyltransferase of rat liver microsomes
Proc. Natl. Acad. Sci. USA
72
600-603
1975
Rattus norvegicus
brenda
Miki, Y.; Hosaka, K.; Yamashita, S.; Handa, H.; Numa, S.
Acyl-acceptor specificities of 1-acylglycerolphosphate acyltransferase and 1-acylglycerophosphorylcholine acyltransferase resolved from rat liver microsomes
Eur. J. Biochem.
81
433-441
1977
Rattus norvegicus
brenda
Holub, B.J.; Macnaughton, J.A.; Piekarski, J.
Synthesis of 1-palmitoyl and 1-stearoyl phosphatidylcholines from mixtures of acyl acceptors via acyl-CoA:1-acyl-sn-glycero-3-phosphorylcholine acyltransferase in liver microsomes
Biochim. Biophys. Acta
572
413-422
1979
Rattus norvegicus
brenda
Hasegawa-Sasaki, H.; Ohno, K.
Extraction and partial purification of acyl-CoA:1-acyl-sn-glycero-3-phosphocholine acyltransferase from rat liver microsomes
Biochim. Biophys. Acta
617
205-217
1980
Rattus norvegicus
brenda
Renooij, W.; Snyder, F.
Transmembrane orientation of palmitoyl-CoA: lysophosphatidylcholine acyltransferase in microsomes isolated from an alveolar type II cell adenoma and rat liver
Biochim. Biophys. Acta
666
468-474
1981
Mus musculus, Mus musculus BALB/c, Rattus norvegicus
brenda
Iritani, N.; Ikeda, Y.; Kajitani, H.
Selectivities of 1-acylglycerophosphorylcholine acyltransferase and acyl-CoA synthetase for n-3 polyunsaturated fatty acids in platelets and liver microsomes
Biochim. Biophys. Acta
793
416-422
1984
Rattus norvegicus
brenda
Momchilova, A.B.; Markovska, T.T.; Koshlukova, S.E.; Koumanov, K.S.; Pankov, R.G.
Phospholipid modifications influence acyl-CoA:1-acyl-glycero-3-phosphocholine O-acyltransferase in rat liver plasma membranes
Biochem. Cell Biol.
69
643-648
1991
Rattus norvegicus
brenda
Yamashita, S.; Hosaka, K.; Numa, S.
Acyl-donor specificities of partially purified 1-acylglycerophosphate acyltransferase, 2-acylglycerophosphate acyltransferase and 1-acylglycerophosphorylcholine acyltransferase from rat-liver microsomes
Eur. J. Biochem.
38
25-31
1973
Rattus norvegicus
brenda
Alberghina, M.; Lupo, G.; Anfuso, C.D.; el Ghonemy, S.H.
Lipid peroxidation inhibits acyl-CoA:-1-acyl-sn-glycero-3-phosphocholine O-acyltransferase but not CTP: phosphocholine cytidylyltransferase activity in rat brain membranes
Neurochem. Int.
26
477-487
1995
Rattus norvegicus
brenda
Fyrst, H.; Pham, D.V.; Lubin, B.H.; Kuypers, F.A.
Formation of vesicles by the action of acyl-CoA:1-acyllsophosphatidylcholine acyltransferase from rat liver microsomes: optimal solubilization conditions and analysis of lipid composition and enzyme activity
Biochemistry
35
2644-2650
1996
Rattus norvegicus
brenda
Chambers, K.; Brown, W.J.
Characterization of a novel CI-976-sensitive lysophospholipid acyltransferase that is associated with the Golgi complex
Biochem. Biophys. Res. Commun.
313
681-686
2004
Rattus norvegicus
brenda
Drecktrah, D.; Chambers, K.; Racoosin, E.L.; Cluett, E.B.; Gucwa, A.; Jackson, B.; Brown, W.J.
Inhibition of a Golgi complex lysophospholipid acyltransferase induces membrane tubule formation and retrograde trafficking
Mol. Biol. Cell
14
3459-3469
2003
Rattus norvegicus
brenda
Nakanishi, H.; Shindou, H.; Hishikawa, D.; Harayama, T.; Ogasawara, R.; Suwabe, A.; Taguchi, R.; Shimizu, T.
Cloning and characterization of mouse lung-type acyl-CoA:lysophosphatidylcholine acyltransferase 1 (LPCAT1). Expression in alveolar type II cells and possible involvement in surfactant production
J. Biol. Chem.
281
20140-20147
2006
Rattus norvegicus (Q1HAQ0), Mus musculus (Q3TFD2), Mus musculus
brenda
Chambers, K.; Judson, B.; Brown, W.J.
A unique lysophospholipid acyltransferase (LPAT) antagonist, CI-976, affects secretory and endocytic membrane trafficking pathways
J. Cell Sci.
118
3061-3071
2005
Homo sapiens, Rattus norvegicus
brenda
Chen, X.; Hyatt, B.A.; Mucenski, M.L.; Mason, R.J.; Shannon, J.M.
Identification and characterization of a lysophosphatidylcholine acyltransferase in alveolar type II cells
Proc. Natl. Acad. Sci. USA
103
11724-11729
2006
Rattus norvegicus (Q1HAQ0), Mus musculus (Q3TFD2), Mus musculus
brenda
Jackson, S.K.; Abate, W.; Tonks, A.J.
Lysophospholipid acyltransferases: novel potential regulators of the inflammatory response and target for new drug discovery
Pharmacol. Ther.
119
104-114
2008
Bos taurus, Rattus norvegicus, Mus musculus (Q3TFD2), Homo sapiens (Q8NF37)
brenda
Yamazaki, Y.; Yasuda, K.; Matsuyama, T.; Ishihara, T.; Higa, R.; Sawairi, T.; Yamaguchi, M.; Egi, M.; Akai, S.; Miyase, T.; Ikari, A.; Miwa, M.; Sugatani, J.
A Penicillium sp. F33 metabolite and its synthetic derivatives inhibit acetyl-CoA:1-O-alkyl-sn-glycero-3-phosphocholine acetyltransferase (a key enzyme in platelet-activating factor biosynthesis) and carrageenan-induced paw edema in mice
Biochem. Pharmacol.
86
632-644
2013
Rattus norvegicus
brenda
Fisher, A.B.; Dodia, C.; Sorokina, E.M.; Li, H.; Zhou, S.; Raabe, T.; Feinstein, S.I.
A novel lysophosphatidylcholine acyl transferase activity is expressed by peroxiredoxin 6
J. Lipid Res.
57
587-596
2016
Mus musculus (O08709), Mus musculus, Rattus norvegicus (O35244), Homo sapiens (P30041), Mus musculus C57BL/6J (O08709)
brenda