Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

BRENDA Home
show all | hide all No of entries

Information on EC 2.3.1.22 - 2-acylglycerol O-acyltransferase and Organism(s) Danio rerio and UniProt Accession A2BHM7

for references in articles please use BRENDA:EC2.3.1.22
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments
Various 2-acylglycerols can act as acceptor; palmitoyl-CoA and other long-chain acyl-CoAs can act as donors. The sn-1 position and the sn-3 position are both acylated, at about the same rate.
Specify your search results
Select one or more organisms in this record: ?
This record set is specific for:
Danio rerio
UNIPROT: A2BHM7
Show additional data
Do not include text mining results
Include (text mining) results
Include results (AMENDA + additional results, but less precise)
Word Map
The taxonomic range for the selected organisms is: Danio rerio
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
mgat1, mgat2, mgat3, mogat1, lpgat1, mogat2, mogat3, acyl-coa:monoacylglycerol acyltransferase, monoacylglycerol o-acyltransferase 1, monoacylglycerol o-acyltransferase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
monoacylglycerol acyltransferase
-
acyl coenzyme A-monoglyceride acyltransferase
-
-
-
-
acyl-CoA:monoacylglycerol transferase
-
-
-
-
acylglycerol palmitoyltransferase
-
-
-
-
monoacylglycerol acyltransferase
monoglyceride acyltransferase
-
-
-
-
palmitoyltransferase, acylglycerol
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Acyl group transfer
-
-
-
-
PATHWAY SOURCE
PATHWAYS
-
-
SYSTEMATIC NAME
IUBMB Comments
acyl-CoA:2-acylglycerol O-acyltransferase
Various 2-acylglycerols can act as acceptor; palmitoyl-CoA and other long-chain acyl-CoAs can act as donors. The sn-1 position and the sn-3 position are both acylated, at about the same rate.
CAS REGISTRY NUMBER
COMMENTARY hide
9055-17-8
-
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
monoacylglycerol + fatty acyl-CoA
diacylglycerol + CoA
show the reaction diagram
-
-
-
?
monoacylglycerol + fatty acyl-CoA
diacylglycerol + CoA
show the reaction diagram
-
-
-
?
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
monoacylglycerol + fatty acyl-CoA
diacylglycerol + CoA
show the reaction diagram
-
-
-
?
monoacylglycerol + fatty acyl-CoA
diacylglycerol + CoA
show the reaction diagram
-
-
-
?
pI VALUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
8.5
predicted from sequence analysis
9
predicted from sequence analysis
9.3
predicted from sequence analysis
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
zebrafish
UniProt
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
metabolism
diacylglyceride synthesis, involved in triglyceride and phospholipid synthesis
physiological function
involvid in energy storage (fat digestion and absorption), lipoprotein and membrane formation, intracellular signaling for protein kinase activation
metabolism
diacylglyceride synthesis, involved in triglyceride and phospholipid synthesis
physiological function
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
A2BHM7_DANRE
336
0
37801
TrEMBL
-
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
37800
predicted from sequence analysis, 5395 bp, 336 amino acids, gene location on chromosome 5
37710
predicted from sequence analysis, 10577 bp, 334 amino acids, gene location on chromosome 23
38010
predicted from sequence analysis, 23470 bp, 330 amino acids, gene location on chromosome 10
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Holmes, R.
Comparative genomics and proteomics of vertebrate diacylglycerol acyltransferase (DGAT), acyl CoA wax alcohol acyltransferase (AWAT) and monoacylglycerol acyltransferase (MGAT)
Comp. Biochem. Physiol. D
5
45-54
2010
Danio rerio (A2BHM7), Danio rerio (B0JZB3), Danio rerio (Q5XJR1), Danio rerio, Monodelphis domestica
Manually annotated by BRENDA team