Information on EC 2.2.1.2 - transaldolase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Specify your search results
Mark a special word or phrase in this record:
Select one or more organisms in this record:
Show additional data
Do not include text mining results
Include (text mining) results (more...)
Include results (AMENDA + additional results, but less precise; more...)


The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea

EC NUMBER
COMMENTARY
2.2.1.2
-
RECOMMENDED NAME
GeneOntology No.
transaldolase
REACTION TYPE
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
aldehyde group transfer
-
-
-
-
PATHWAY
KEGG Link
MetaCyc Link
Bifidobacterium shunt
-
Biosynthesis of secondary metabolites
-
formaldehyde assimilation II (RuMP Cycle)
-
formaldehyde assimilation III (dihydroxyacetone cycle)
-
Metabolic pathways
-
Microbial metabolism in diverse environments
-
Pentose phosphate pathway
-
pentose phosphate pathway (non-oxidative branch)
-
Rubisco shunt
-
SYSTEMATIC NAME
IUBMB Comments
sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase
-
SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
Atalp
Blastobotrys adeninivorans LS3
Q0E4W0
-
-
dihydroxyacetone synthase
-
-
-
-
dihydroxyacetonetransferase
-
-
-
-
formaldehyde transketolase
-
-
-
-
hTAL
-
-
NQM1/YGR043C
P53228
-
TAL
Q2TUQ1
-
Tal1
P15019
gene name
TALase
-
-
TALDO
-
-
transaldolase
-
-
transaldolase
-
-
transaldolase
-
-
transaldolase
P53228
-
transaldolase
Trichosporonoides megachiliensis
-
-
transaldolase 1
-
-
transaldolase STY3758
-
-
transaldolase1
-
-
CAS REGISTRY NUMBER
COMMENTARY
9014-46-4
-
ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
; decrease in enzyme expression under phosphate starvation
-
-
Manually annotated by BRENDA team
P1, 2 isoenzymes: C1-inducible enzyme, C2-constitutive enzyme
-
-
Manually annotated by BRENDA team
Bifidobacterium bifidum A8
-
-
-
Manually annotated by BRENDA team
; increased expression in media containing 5% NaCl
-
-
Manually annotated by BRENDA team
strain LS3, gene ATAL
SwissProt
Manually annotated by BRENDA team
Blastobotrys adeninivorans LS3
strain LS3, gene ATAL
SwissProt
Manually annotated by BRENDA team
Chromatium sp.
-
-
-
Manually annotated by BRENDA team
var. neoformans, strain JEC21
-
-
Manually annotated by BRENDA team
3 isoenzymes: I, II, III
-
-
Manually annotated by BRENDA team
gene talA; recombinant enzyme
-
-
Manually annotated by BRENDA team
Escherichia coli K12
K12
-
-
Manually annotated by BRENDA team
Euglena sp.
-
-
-
Manually annotated by BRENDA team
transaldolase/glucose-6-phosphate isomerase bifunctional enzyme
Swissprot
Manually annotated by BRENDA team
; pregnant and nonpregnant women
-
-
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
male, homo- or heterozygously lacking transaldolase
-
-
Manually annotated by BRENDA team
2 isoforms
-
-
Manually annotated by BRENDA team
Tetranychus telarius
-
-
-
Manually annotated by BRENDA team
Trichosporonoides megachiliensis
strain SN-G42 and 124A
-
-
Manually annotated by BRENDA team
Trichosporonoides megachiliensis SN-G42
strain SN-G42 and 124A
-
-
Manually annotated by BRENDA team
METALS and IONS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
additional information
-
no metal requirement
kcat/KM VALUE [1/mMs-1]
kcat/KM VALUE [1/mMs-1] Maximum
SUBSTRATE
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
IMAGE
139.9
-
D-erythrose-4-phosphate
-
-
195567
10.38
-
D-fructose-6-phosphate
-
-
80918
9
-
D-glyceraldehyde
-
mutant F178, pH 8.5, 30C
9225
4.3
-
DL-glyceraldehyde
-
mutant F178, pH 8.5, 30C
10100
5000
-
glyceraldehyde 3-phosphate
-
mutant F178, pH 8.5, 30C
11067
6600
-
glyceraldehyde 3-phosphate
-
wild-type, pH 8.5, 30C
11067
pI VALUE
pI VALUE MAXIMUM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
4.5
-
-
isoelectric focusing-PAGE
5.14
-
-
isoelectric focusing
PDB
SCOP
CATH
ORGANISM
Bacillus subtilis (strain 168)
Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
Escherichia coli (strain K12)
Escherichia coli (strain K12)
Escherichia coli (strain K12)
Escherichia coli (strain K12)
Escherichia coli (strain K12)
Escherichia coli (strain K12)
Escherichia coli (strain K12)
Escherichia coli (strain K12)
Escherichia coli O104:H4 (strain 2009EL-2071)
Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)
Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)
Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)
Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)
Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)
Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)
Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)
Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)
Prochlorococcus marinus (strain MIT 9312)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
pH STABILITY
pH STABILITY MAXIMUM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
4
9
-
stable
6
9
-
80% loss of activity with Tris/HCl buffer at pH 7.5, 95% loss of activity with Tris/HCl buffer at pH 9.0, 62% loss of activity with glycine/NaOH buffer at pH 9.0, about half of enzyme activity lost with phosphate buffer at pH 6.0
7
-
-
room temperature, stable for a few hours
GENERAL STABILITY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
complete inactivation by treatment with sodium borohydride at pH 6.0 and 2C in absence of substrate D-fructose 6-phosphate
-
highly purified preparations can be dialyzed with little loss of activity
-
stable to lyophilization
-
STORAGE STABILITY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
-20C, stable for at least 2 months
-
2C, for at least 8 weeks
-
isoenzymes I and III are stable in the cold in the crystalline form for over 1 year
-
30C, 1 h, 20% activity lost
-
40C, 1 h, 40% activity lost
-
-16C, 10-20% loss of activity after 1 week
-
-20C, stable for several months
-