Information on EC 2.1.1.39 - inositol 3-methyltransferase

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The expected taxonomic range for this enzyme is: Gunneridae

SplaateEC_Number,Commentary
EC NUMBER
COMMENTARY
2.1.1.39
-
SplaateRecommended_Name,GO_Number
RECOMMENDED NAME
GeneOntology No.
inositol 3-methyltransferase
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SplaateReaction,Reaction_id,Commentary,IF(Commentary != '',Organism,'') ,IF(Commentary != '',Literature,'')
REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT
LITERATURE
S-adenosyl-L-methionine + myo-inositol = S-adenosyl-L-homocysteine + 1D-3-O-methyl-myo-inositol
show the reaction diagram
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-
-
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SplaateReaction_Type,Organism,Commentary,Literature
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
methyl group transfer
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-
-
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SplaatePathway,BRENDA_Link,KEGG_Link,MetaCyc_Link,Source_Database
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
Inositol phosphate metabolism
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-
SplaateSystematic_Name,Commentary_IUBMB
SYSTEMATIC NAME
IUBMB Comments
S-adenosyl-L-methionine:1D-myo-inositol 3-O-methyltransferase
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SplaateSynonyms,Organism,Commentary,Literature
SYNONYMS
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
inositol 3-O-methyltransferase
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-
-
-
inositol L-1-methyltransferase
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-
-
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methyltransferase, inositol L-1-
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-
-
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myo-inositol 1-methyltransferase
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-
-
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myo-inositol O-Me transferase
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S-adenosyl-L-methionine:myo-inositol 1-O-methyltransferase
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-
-
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S-adenosylmethionine:myo-inositol 1-methyltransferase
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-
-
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SplaateCAS_Registry_Number,Commentary
CAS REGISTRY NUMBER
COMMENTARY
37257-05-9
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SplaateOrganism, Commentary,Literature, Sequence_Code,Sequence_db,Textmining
ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SplaateGeneral_Information, Organism, Commentary, Literature
SplaateSubstrates,Products,id,Organism_Substrates,Commentary_Substrates, Literature_Substrates, Commentary_Products, Literature_Products,Reversibility
SUBSTRATE
PRODUCT                      
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
LITERATURE
(Substrate)
COMMENTARY
(Product)
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
S-adenosyl-L-methionine + myo-inositol
S-adenosyl-L-homocysteine + 1D-3-O-methyl-myo-inositol + H+
show the reaction diagram
-
-
-
?
S-adenosyl-L-methionine + myo-inositol
S-adenosyl-L-homocysteine + 1D-3-O-methyl-myo-inositol + H+
show the reaction diagram
-
-
-
?
S-adenosyl-L-methionine + myo-inositol
S-adenosyl-L-homocysteine + 1D-3-O-methyl-myo-inositol + H+
show the reaction diagram
-
-
i.e. pinitol
?
S-adenosyl-L-methionine + myo-inositol
S-adenosyl-L-homocysteine + 1D-3-O-methyl-myo-inositol + H+
show the reaction diagram
-
-
i.e. pinitol
?
additional information
?
-
-
ozone, like salinity, elicits an increase in the transcript and protein abundance of myo-inositol O-Me transferase
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-
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SplaateNatural_Substrates,Natural_Products,id,Organism_Substrates,Commentary_Substrates,Literature_Substrates,Commentary_Products,Literature_Products,Reversibility
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
LITERATURE
(Substrate)
COMMENTARY
(Product)
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
S-adenosyl-L-methionine + myo-inositol
S-adenosyl-L-homocysteine + 1D-3-O-methyl-myo-inositol + H+
show the reaction diagram
-
-
-
?
S-adenosyl-L-methionine + myo-inositol
S-adenosyl-L-homocysteine + 1D-3-O-methyl-myo-inositol + H+
show the reaction diagram
-
-
-
?
additional information
?
-
-
ozone, like salinity, elicits an increase in the transcript and protein abundance of myo-inositol O-Me transferase
-
-
-
SplaateCofactor,Organism,Commentary,Literature,Filename
SplaateMetals_Ions,Organism,Commentary, Literature
SplaateInhibitors, Organism, Commentary, Literature,Filename
INHIBITORS
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
iodoacetate
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-
N-ethylmaleimide
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p-chloromercuribenzoate
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SplaateActivating_Compound, Organism, Commentary, Literature,Filename
SplaateKM_Value,KM_Value_Maximum, Substrate,Organism, Commentary, Literature, Filename
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
2.5
myo-inositol
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-
0.8
S-adenosyl-L-methionine
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-
SplaateTurnover_Number, Turnover_Number_Maximum, Substrate,Organism,Commentary, Literature, Filename
SplaateKCat_KM_Value,KCat_KM_Value_Maximum, Substrate,Organism, Commentary, Literature, Filename
SplaateKI_Value,KI_Value_Maximum, Inhibitor,Organism, Commentary, Literature, Filename
SplaateIC50_Value,IC50_Value_Maximum, Inhibitor,Organism, Commentary, Literature, Filename
SplaateSpecific_Activity, Specific_Activity_Maximum, Organism ,Commentary, Literature
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
0.0078
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-
additional information
-
-
SplaatepH_Optimum, pH_Optimum_Maximum, Organism, Commentary, Literature
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
SplaatepH_Range,pH_Range_Maximum, Organism,Commentary, Literature
pH RANGE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
6.5 - 8
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pH 6.5: about 20% of activity maximum, pH 8.0: about 15% of activity maximum
SplaateTemperature_Optimum, Temperature_Optimum_Maximum, Organism, Commentary, Literature
SplaateTemperature_Range, Temperature_Range_Maximum, Organism, Commentary, Literature
SplaatepI_Value,pI_Value_Maximum, Organism,Commentary, Literature
pI VALUE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
7.1
-
isoelectric focusing
SplaateSource_Tissue, Organism, Commentary, Literature, Textmining
SplaateLocalization, Organism, Commentary, id_go, Literature, Textmining
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY
GeneOntology No.
LITERATURE
SOURCE
SplaatePDB,PDB,PDB,Organism,Uniprot_ID
SplaateMolecular_Weight, Molecular_Weight_Maximum, Organism, Commentary, Literature
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
27000
-
gel filtration
485319
30000
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gel filtration
639474
SplaateSubunits, Organism, Commentary, Literature
SUBUNITS
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
monomer
-
1 * 27000, SDS-PAGE
SplaatePosttranslational_Modification, Organism, Commentary, Literature
SplaateCommentary, Organism, Literature
SplaatepH_Stability,pH_Stability_Maximum, Organism, Commentary, Literature
SplaateTemperature_Stability,Temperature_Stability_Maximum, Organism, Commentary, Literature
SplaateGeneral_Stability, Organism, Literature
SplaateOrganic_Solvent, Organism, Commentary, Literature
SplaateOxidation_Stability,Organism,Literature
SplaateStorage_Stability, Organism, Literature
SplaateCommentary, Organism, Literature
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
SplaateCommentary, Organism, Literature
SplaateCommentary, Organism, Literature
SplaateEngineering, Organism, Commentary, Literature
SplaateCommentary, Organism, Literature
SplaateApplication,Organism,Commentary,Literature