Information on EC 2.1.1.39 - inositol 3-methyltransferase

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The expected taxonomic range for this enzyme is: Gunneridae

EC NUMBER
COMMENTARY
2.1.1.39
-
RECOMMENDED NAME
GeneOntology No.
inositol 3-methyltransferase
REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
S-adenosyl-L-methionine + myo-inositol = S-adenosyl-L-homocysteine + 1D-3-O-methyl-myo-inositol
show the reaction diagram
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
methyl group transfer
-
-
-
-
PATHWAY
KEGG Link
MetaCyc Link
Inositol phosphate metabolism
-
SYSTEMATIC NAME
IUBMB Comments
S-adenosyl-L-methionine:1D-myo-inositol 3-O-methyltransferase
-
SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
inositol 3-O-methyltransferase
-
-
-
-
inositol L-1-methyltransferase
-
-
-
-
methyltransferase, inositol L-1-
-
-
-
-
myo-inositol 1-methyltransferase
-
-
-
-
myo-inositol O-Me transferase
-
-
S-adenosyl-L-methionine:myo-inositol 1-O-methyltransferase
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-
-
-
S-adenosylmethionine:myo-inositol 1-methyltransferase
-
-
-
-
CAS REGISTRY NUMBER
COMMENTARY
37257-05-9
-
ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
SUBSTRATE
PRODUCT                      
REACTION DIAGRAM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
(Substrate)
LITERATURE
(Substrate)
COMMENTARY
(Product)
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
S-adenosyl-L-methionine + myo-inositol
S-adenosyl-L-homocysteine + 1D-3-O-methyl-myo-inositol + H+
show the reaction diagram
-
-
-
?
S-adenosyl-L-methionine + myo-inositol
S-adenosyl-L-homocysteine + 1D-3-O-methyl-myo-inositol + H+
show the reaction diagram
-
-
-
?
S-adenosyl-L-methionine + myo-inositol
S-adenosyl-L-homocysteine + 1D-3-O-methyl-myo-inositol + H+
show the reaction diagram
-
-
i.e. pinitol
?
S-adenosyl-L-methionine + myo-inositol
S-adenosyl-L-homocysteine + 1D-3-O-methyl-myo-inositol + H+
show the reaction diagram
-
-
i.e. pinitol
?
additional information
?
-
-
ozone, like salinity, elicits an increase in the transcript and protein abundance of myo-inositol O-Me transferase
-
-
-
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
(Substrate)
LITERATURE
(Substrate)
COMMENTARY
(Product)
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
S-adenosyl-L-methionine + myo-inositol
S-adenosyl-L-homocysteine + 1D-3-O-methyl-myo-inositol + H+
show the reaction diagram
-
-
-
?
S-adenosyl-L-methionine + myo-inositol
S-adenosyl-L-homocysteine + 1D-3-O-methyl-myo-inositol + H+
show the reaction diagram
-
-
-
?
additional information
?
-
-
ozone, like salinity, elicits an increase in the transcript and protein abundance of myo-inositol O-Me transferase
-
-
-
INHIBITORS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
IMAGE
N-ethylmaleimide
-
-
p-chloromercuribenzoate
-
-
KM VALUE [mM]
KM VALUE [mM] Maximum
SUBSTRATE
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
IMAGE
2.5
-
myo-Inositol
-
-
0.8
-
S-adenosyl-L-methionine
-
-
SPECIFIC ACTIVITY [µmol/min/mg]
SPECIFIC ACTIVITY MAXIMUM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
0.0078
-
-
-
additional information
-
-
-
pH OPTIMUM
pH MAXIMUM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
pH RANGE
pH RANGE MAXIMUM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
6.5
8
-
pH 6.5: about 20% of activity maximum, pH 8.0: about 15% of activity maximum
pI VALUE
pI VALUE MAXIMUM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
7.1
-
-
isoelectric focusing
LOCALIZATION
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
GeneOntology No.
LITERATURE
SOURCE
MOLECULAR WEIGHT
MOLECULAR WEIGHT MAXIMUM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
27000
-
-
gel filtration
30000
-
-
gel filtration
SUBUNITS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
monomer
-
1 * 27000, SDS-PAGE
Purification/COMMENTARY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE