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Information on EC 2.1.1.37 - DNA (cytosine-5-)-methyltransferase and Organism(s) Arabidopsis thaliana and UniProt Accession Q94F88

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EC Tree
     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.37 DNA (cytosine-5-)-methyltransferase
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This record set is specific for:
Arabidopsis thaliana
UNIPROT: Q94F88 not found.
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Word Map
The taxonomic range for the selected organisms is: Arabidopsis thaliana
The enzyme appears in selected viruses and cellular organisms
Synonyms
dnmt1, dnmt3a, dna methyltransferase, dnmt3b, dna methyltransferase 1, dnmt2, dna mtase, nsun2, dna methylase, dna methyltransferase 3a, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
C5-MTase
cytosine 5-methyltransferase
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cytosine DNA methylase
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cytosine DNA methyltransferase
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cytosine-specific DNA methyltransferase
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DCMT
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deoxyribonucleate methylase
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deoxyribonucleate methyltransferase
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deoxyribonucleic (cytosine-5-)-methyltransferase
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deoxyribonucleic acid (cytosine-5-)-methyltransferase
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deoxyribonucleic acid methylase
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deoxyribonucleic acid methyltransferase
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deoxyribonucleic acid modification methylase
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deoxyribonucleic methylase
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DNA 5-cytosine methylase
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DNA cytosine c5 methylase
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DNA cytosine methylase
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DNA methylase
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DNA methyltransferase
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DNA transmethylase
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DNA-cytosine 5-methylase
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DNA-cytosine methyltransferase
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EcoRI methylase
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methylphosphotriester-DNA methyltransferase
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methyltransferase, deoxyribonucleate
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type II DNA methylase
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
methyl group transfer
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PATHWAY SOURCE
PATHWAYS
SYSTEMATIC NAME
IUBMB Comments
S-adenosyl-L-methionine:DNA (cytosine-5-)-methyltransferase
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CAS REGISTRY NUMBER
COMMENTARY hide
9037-42-7
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
DNA + S-adenosyl-L-methionine
DNA containing 5-methylcytosine + S-adenosyl-L-homocysteine
show the reaction diagram
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?
DNA fragment RPS + S-adenosyl-L-methionine
DNA fragment RPS containing 5-methylcytosine + S-adenosyl-L-homocysteine
show the reaction diagram
RPS is a repetitive hypermethylated DNA fragment from Petunia hybrida. CG methylation, CNG methylation, and CNN methylation. MET1 maintains CG methylation, and DRM1/2 and CMT3 act redundantly to enforce non-CG methylation, unusual cooperative activity of all three DNA methyltransferases is therefore required for maintenance of both CG and non-CG methylation in RPS. Arabidopsis thaliana does not contain any RPS homologues. Methylation at the CCmTGG site also requires DRM1/2, MET1, and, to a lesser extent, CMT3
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additional information
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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
DNA + S-adenosyl-L-methionine
DNA containing 5-methylcytosine + S-adenosyl-L-homocysteine
show the reaction diagram
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?
additional information
?
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COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
S-adenosyl-L-methionine
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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
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gene sequences contain nuclear localization signals
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
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identification of 14 C5-MTase genes in wild forms of Arabidopsis thaliana, located on the same chromosome. The promoters of most C5-MTase genes contain light-, heat-, cold-, and salt-induced cis-regulated elements
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
CMT3_ARATH
839
0
94905
Swiss-Prot
other Location (Reliability: 4)
PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Singh, A.; Zubko, E.; Meyer, P.
Cooperative activity of DNA methyltransferases for maintenance of symmetrical and non-symmetrical cytosine methylation in Arabidopsis thaliana
Plant J.
56
814-823
2008
Arabidopsis thaliana (Q94F88), Arabidopsis thaliana
Manually annotated by BRENDA team
Wang, P.; Gao, C.; Bian, X.; Zhao, S.; Zhao, C.; Xia, H.; Song, H.; Hou, L.; Wan, S.; Wang, X.
Genome-wide identification and comparative analysis of cytosine-5 DNA methyltransferase and demethylase families in wild and cultivated peanut
Front. Plant Sci.
7
7
2016
Arabidopsis thaliana
Manually annotated by BRENDA team