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Information on EC 2.1.1.289 - cobalt-precorrin-7 (C5)-methyltransferase and Organism(s) Methanothermobacter thermautotrophicus and UniProt Accession O26249

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EC Tree
     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.289 cobalt-precorrin-7 (C5)-methyltransferase
IUBMB Comments
This enzyme catalyses the methylation at C-5 of cobalt-precorrin-7, a step in the anaerobic (early cobalt insertion) adenosylcobalamin biosynthesis pathway. The equivalent activity in the aerobic adenosylcobalamin biosynthesis pathway is catalysed by the bifunctional enzyme EC 2.1.1.132, precorrin-6B C5,15-methyltransferase (decarboxylating).
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Methanothermobacter thermautotrophicus
UNIPROT: O26249
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The taxonomic range for the selected organisms is: Methanothermobacter thermautotrophicus
The expected taxonomic range for this enzyme is: Bacteria, Archaea
Synonyms
cbiet, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
CbiE
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PATHWAY SOURCE
PATHWAYS
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SYSTEMATIC NAME
IUBMB Comments
S-adenosyl-L-methionine:precorrin-7 C5-methyltransferase
This enzyme catalyses the methylation at C-5 of cobalt-precorrin-7, a step in the anaerobic (early cobalt insertion) adenosylcobalamin biosynthesis pathway. The equivalent activity in the aerobic adenosylcobalamin biosynthesis pathway is catalysed by the bifunctional enzyme EC 2.1.1.132, precorrin-6B C5,15-methyltransferase (decarboxylating).
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
metabolism
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the CbiE enzyme participates in the biosynthesis of vitamin B12