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Information on EC 2.1.1.206 - tRNA (cytidine56-2'-O)-methyltransferase and Organism(s) Pyrococcus abyssi and UniProt Accession Q9UYD1

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EC Tree
     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.206 tRNA (cytidine56-2'-O)-methyltransferase
IUBMB Comments
The archaeal enzyme specifically catalyses the S-adenosyl-L-methionine dependent 2'-O-ribose methylation of cytidine at position 56 in tRNA transcripts.
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This record set is specific for:
Pyrococcus abyssi
UNIPROT: Q9UYD1
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Word Map
The taxonomic range for the selected organisms is: Pyrococcus abyssi
The expected taxonomic range for this enzyme is: Archaea, Bacteria
Reaction Schemes
Synonyms
atrm56, transfer rna methyltransferase, trm56, pab1040, ta0931, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
tRNA ribose 2'-O-methyltransferase aTrm56
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SYSTEMATIC NAME
IUBMB Comments
S-adenosyl-L-methionine:tRNA (cytidine56-2'-O)-methyltransferase
The archaeal enzyme specifically catalyses the S-adenosyl-L-methionine dependent 2'-O-ribose methylation of cytidine at position 56 in tRNA transcripts.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
S-adenosyl-L-methionine + cytidine56 in tRNA
S-adenosyl-L-homocysteine + 2'-O-methylcytidine56 in tRNA
show the reaction diagram
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
S-adenosyl-L-methionine + cytidine56 in tRNA
S-adenosyl-L-homocysteine + 2'-O-methylcytidine56 in tRNA
show the reaction diagram
-
-
-
?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
SwissProt
Manually annotated by BRENDA team
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
22000
x * 22000, SDS-PAGE
22262
x * 22262, calculated from sequence
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expression in Escherichia coli BL21
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Renalier, M.H.; Joseph, N.; Gaspin, C.; Thebault, P.; Mougin, A.
The Cm56 tRNA modification in archaea is catalyzed either by a specific 2'-O-methylase, or a C/D sRNP
RNA
11
1051-1063
2005
Pyrococcus abyssi (Q9UYD1), Pyrococcus abyssi
Manually annotated by BRENDA team