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Information on EC 2.1.1.125 - histone-arginine N-methyltransferase and Organism(s) Arabidopsis thaliana and UniProt Accession Q8GWT4

for references in articles please use BRENDA:EC2.1.1.125
deleted, now covered by EC 2.1.1.319, type I protein arginine methyltransferase, EC 2.1.1.320, type II protein arginine methyltransferase, EC 2.1.1.321, type III protein arginine methyltransferase and EC 2.1.1.322, type IV protein arginine methyltransferase
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EC Tree
     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.125 histone-arginine N-methyltransferase
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
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PRMT5 is a type II protein arginine methyltransferase that, in winter-annual strains, is required for epigenetic silencing of FLC, a member of a clade of floral repressors, and for the vernalization-mediated histone modifications characteristic of the vernalized state, overview. Arginine methylation of FLC chromatin is part of the histone code that is required for mitotic stability of the vernalized state
malfunction
physiological function
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the methyltransferase activity of PRMT10 is essential for repressing flowering locus C expression and promoting flowering in Arabidopsis