Information on EC 1.8.5.5 - thiosulfate reductase (quinone)

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The expected taxonomic range for this enzyme is: Salmonella enterica

EC NUMBER
COMMENTARY hide
1.8.5.5
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RECOMMENDED NAME
GeneOntology No.
thiosulfate reductase (quinone)
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
sulfite + hydrogen sulfide + a quinone = thiosulfate + a quinol
show the reaction diagram
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
thiosulfate disproportionation III (quinone)
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Sulfur metabolism
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Microbial metabolism in diverse environments
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SYSTEMATIC NAME
IUBMB Comments
sulfite,hydrogen sulfide:quinone oxidoreductase
The enzyme, characterized from the bacterium Salmonella enterica, is similar to EC 1.1.5.6, formate dehydrogenase-N. It contains a molybdopterin-guanine dinucleotide, five [4Fe-4S] clusters and two heme b groups. The reaction occurs in vivo in the direction of thiosulfate disproportionation, which is highly endergonic. It is driven by the proton motive force that occurs across the cytoplasmic membrane.
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
P37600 i.e. subunit PhsA, P0A1I1 i.e. subunit PhsB
P37600 and P0A1I1
UniProt
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
sulfite + hydrogen sulfide + menaquinone
thiosulfate + menaquinol
show the reaction diagram
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thiosulfate reductase is able to catalyze the combined oxidation of sulfide and sulfite to thiosulfate in a reverse of the physiological reaction
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r
thiosulfate + menaquinol
sulfite + hydrogen sulfide + menaquinone
show the reaction diagram
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r
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
menaquinol
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menaquinol is the sole electron donor to thiosulfate reductase
SUBUNITS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
EXPRESSION
ORGANISM
UNIPROT
LITERATURE
oxygen and thiosulfate control of Phs expression involves negative regulation
APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
environmental protection