Reference on EC 1.8.5.1 - glutathione dehydrogenase (ascorbate)
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Stankova, L.; Bigley, R.; Wyss, S.R.; Aebi, H.
Catalase and dehydroascorbate reductase in human polymorphonuclear leukocytes (PMN): possible functional relationship
Experientia
35
852-853
1979
Homo sapiens
Murthy, S.S.; Zilinskas, B.A.
Molecular cloning and characterization of a cDNA encoding pea monodehydroascorbate reductase
J. Biol. Chem.
269
31129-31133
1994
Electron
Redman, D.G.
Dehydroascorbic acid reductase activity in germinating wheat grains
Chem. Ind.
10
414-415
1974
Triticum aestivum
-
Grimble, R.F.; Hughes, R.E.
The glutathione: dehydroascorbate oxidoreductase activity of guinea-pigs from two different age groups
Life Sci.
7
383-386
1968
Cavia porcellus
Kahnt, W.D.; Mundy, V.; Grosch, W.
Determination of GSH-DH activity (E.C.1.8.5.1) presence of the enzyme in different wheat varieties
Z. Lebensm. Unters. Forsch.
158
77-82
1975
Triticum aestivum
Walther, C.; Grosch, W.
Substrate specificity of the glutathione dehydrogenase (dehydroascorbate reductase) from wheat flour
J. Cereal Sci.
5
299-305
1987
Triticum aestivum
-
Shigeoka, S.; Yasumoto, R.; Onishi, T.; Nakano, Y.; Kitaoka, S.
Properties of monodehydroascorbate reductase and dehydroascorbate reductase and their participation in the regeneration of ascorbate in Euglena gracilis
J. Gen. Microbiol.
133
227-232
1987
Euglena gracilis
-
Foyer, C.H.; Halliwell, B.
Purification and properties of dehydroascorbate reductase from spinach leaves
Phytochemistry
16
1347-1350
1977
Spinacia oleracea
-
Bigley, R.; Riddle, M.; Layman, D.; Stankova, L.
Human cell dehydroascorbate reductase. Kinetic and functional properties
Biochim. Biophys. Acta
659
15-22
1981
Homo sapiens
Stahl, R.L.; Liebes, L.F.; Silber, R.
Glutathione dehydrogenase (ascorbate)
Methods Enzymol.
122
10-12
1986
Spinacia oleracea
Mizohata, E.; Kumei, M.; Matsumura, H.; Shimaoka, T.; Miyake, C.; Inoue, T.; Yokota, A.; Kai, Y.
Crystallization and preliminary X-ray diffraction analysis of glutathione-dependent dehydroascorbate reductase from spinach chloroplasts
Acta Crystallogr. Sect. D
57
1726-1728
2001
BRENDA: Spinacia oleracea
Textmining: Escherichia coli, Electron
Boeck, D.; Grosch, W.
Glutathatione-dehydrogenase of wheat flour. Purification and properties
Z. Lebensm. Unters. Forsch.
162
243-251
1976
Triticum aestivum
Basu, S.; Som, S.; Deb, S.; Mukherjee, D.; Chatterjee, I.B.
Dehydroascorbic acid reduction in human erythrocytes
Biochem. Biophys. Res. Commun.
90
1335-1340
1979
Homo sapiens
Stahl, R.L.; Liebes, L.F.; Farber, C.M.; Silber, R.
A spectrophotometric assay for dehydroascorbate reductase
Anal. Biochem.
131
341-344
1983
Spinacia oleracea
Dipierro, S.; Borraccino, G.
Dehydroascorbate reductase from potato tubers
Phytochemistry
30
427-429
1991
Solanum tuberosum
-
Fornai, F.; Piaggi, S.; Gesi, M.; Saviozzi, M.; Lenzi, P.; Paparelli, A.; Casini, A.F.
Subcellular localization of a glutathione-dependent dehydroascorbate reductase within specific rat brain regions
Neuroscience
104
15-31
2001
BRENDA: Rattus norvegicus
Textmining: Rattus, Areas, Electron
Fornai, F.; Saviozzi, M.; Piaggi, S.; Gesi, M.; Corsini, G.U.; Malvaldi, G.; Casini, A.F.
Localization of a glutathione-dependent dehydroascorbate reductase within the central nervous system of the rat
Neuroscience
94
937-948
1999
BRENDA: Rattus norvegicus
Textmining: Areas, Hippocampus, Rattus
Kim, Y.R.; Kang, S.O.
Purification and characterization of dehydroascorbate reductase from Pleurotus ostreatus
J. Microbiol.
36
164-170
1998
Pleurotus ostreatus
-
Xu, D.P.; Washburn, M.P.; Sun, G.P.; Wells, W.W.
Purification and characterization of a glutathione dependent dehydroascorbate reductase from human erythrocytes
Biochem. Biophys. Res. Commun.
221
117-121
1996
Homo sapiens
Shimaoka, T.; Yokota, A.; Miyake, C.
Purification and characterization of chloroplast dehydroascorbate reductase from spinach leaves
Plant Cell Physiol.
41
1110-1118
2000
Spinacia oleracea
Kato, Y.; Urano, J.i.; Maki, Y.; Ushimaru, T.
Purification and characterization of dehydroascorbate reductase from rice
Plant Cell Physiol.
38
173-178
1997
Oryza sativa
-
Washburn, M.P.; Wells, W.W.
The catalytic mechanism of the glutathione-dependent dehydroascorbate reductase activity of thioltransferase (glutaredoxin)
Biochemistry
38
268-274
1999
Sus scrofa
Paolicchi, A.; Pezzini, A.; Saviozzi, M.; Piaggi, S.; Andreuccetti, M.; Chieli, E.; Malvaldi, G.; Casini, A.F.
Localization of a GSH-dependent dehydroascorbate reductase in rat tissues and subcellular fractions
Arch. Biochem. Biophys.
333
489-495
1996
BRENDA: Rattus norvegicus
Textmining: Rattus, Oryctolagus cuniculus
Maellaro, E.; Del Bello, B.; Sugherini, L.; Comporti, M.; Casini, A.F.
Purification and characterization of glutathione-dependent dehydroascorbate reductase from rat liver
Methods Enzymol.
279
30-35
1997
BRENDA: Rattus norvegicus
Textmining: Rattus
Girardini, J.; Amirante, A.; Zemzoumi, K.; Serra, E.
Characterization of an omega-class glutathione S-transferase from Schistosoma mansoni with glutaredoxin-like dehydroascorbate reductase and thiol transferase activities
Eur. J. Biochem.
269
5512-5521
2002
Schistosoma mansoni, Homo sapiens
Carter, C.J.; Thornburg, R.W.
Tobacco Nectarin III is a bifunctional enzyme with monodehydroascorbate reductase and carbonic anhydrase activities
Plant Mol. Biol.
54
415-425
2004
Dioscorea alata
Zakharyan, R.A.; Sampayo-Reyes, A.; Healy, S.M.; Tsaprailis, G.; Board, P.G.; Liebler, D.C.; Aposhian, H.V.
Human monomethylarsonic acid (MMA(V)) reductase is a member of the glutathione-S-transferase superfamily
Chem. Res. Toxicol.
14
1051-1057
2001
Homo sapiens, Homo sapiens (P78417)
Bachler, C.; Schneider, P.; Bahler, P.; Lustig, A.; Erni, B.
Escherichia coli dihydroxyacetone kinase controls gene expression by binding to transcription factor DhaR
EMBO J.
24
283-293
2005
Butea monosperma, Escherichia coli, Escherichia coli (P76015)
Shimaoka, T.; Miyake, C.; Yokota, A.
Mechanism of the reaction catalyzed by dehydroascorbate reductase from spinach chloroplasts
Eur. J. Biochem.
270
921-928
2003
BRENDA: Spinacia oleracea
Textmining: Escherichia coli, Electron, animal
Ananieva, E.A.; Christov, K.N.; Popova, L.P.
Exogenous treatment with salicylic acid leads to increased antioxidant capacity in leaves of barley plants exposed to paraquat
J. Plant Physiol.
161
319-328
2004
BRENDA: Hordeum vulgare
Textmining: Felis catus
Zhou, W.; Kolb, F.L.; Riechers, D.E.
Identification of proteins induced or upregulated by Fusarium head blight infection in the spikes of hexaploid wheat (Triticum aestivum)
Genome
48
770-780
2005
BRENDA: Triticum aestivum (Q84UH6), Triticum aestivum
Textmining: Fusarium, Fusarium graminearum, Hordeum vulgare, plant
Amako, K.; Ushimaru, T.; Ishikawa, A.; Ogishi, Y.; Kishimoto, R.; Goda, K.
Heterologous expression of dehydroascorbate reductase from rice and its application to determination of dehydroascorbate concentrations
J. Nutr. Sci. Vitaminol.
52
89-95
2006
BRENDA: Oryza sativa
Textmining: Escherichia coli
Chun, J.A.; Seo, J.Y.; Han, M.O.; Lee, J.W.; Yi, Y.B.; Park, G.Y.; Lee, S.W.; Bae, S.C.; Cho, K.J.; Chung, C.H.
Comparative expression and characterization of dehydroascorbate reductase cDNA from transformed sesame hairy roots using real-time RT-PCR
J. Plant Biol.
49
507-512
2006
Sesamum indicum
-
Ushimaru, T.; Nakagawa, T.; Fujioka, Y.; Daicho, K.; Naito, M.; Yamauchi, Y.; Nonaka, H.; Amako, K.; Yamawaki, K.; Murata, N.
Transgenic Arabidopsis plants expressing the rice dehydroascorbate reductase gene are resistant to salt stress
J. Plant Physiol.
163
1179-1184
2006
BRENDA: Oryza sativa
Textmining: Arabidopsis, Arabidopsis thaliana, Homo sapiens
Schmuck, E.M.; Board, P.G.; Whitbread, A.K.; Tetlow, N.; Cavanaugh, J.A.; Blackburn, A.C.; Masoumi, A.
Characterization of the monomethylarsonate reductase and dehydroascorbate reductase activities of Omega class glutathione transferase variants: implications for arsenic metabolism and the age-at-onset of Alzheimers and Parkinsons diseases
Pharmacogenet. Genomics
15
493-501
2005
BRENDA: Homo sapiens (P78417), Homo sapiens
Textmining: Escherichia coli
Yoshida, S.; Tamaoki, M.; Shikano, T.; Nakajima, N.; Ogawa, D.; Ioki, M.; Aono, M.; Kubo, A.; Kamada, H.; Inoue, Y.; Saji, H.
Cytosolic dehydroascorbate reductase is important for ozone tolerance in Arabidopsis thaliana
Plant Cell Physiol.
47
304-308
2006
BRENDA: Arabidopsis thaliana
Textmining: Arabidopsis
Chen, Z.; Gallie, D.R.
Dehydroascorbate reductase affects leaf growth, development, and function
Plant Physiol.
142
775-787
2006
BRENDA: Nicotiana tabacum
Textmining: plant
Song, X.S.; Hu, W.H.; Mao, W.H.; Ogweno, J.O.; Zhou, Y.H.; Yu, J.Q.
Response of ascorbate peroxidase isoenzymes and ascorbate regeneration system to abiotic stresses in Cucumis sativus L
Plant Physiol. Biochem.
43
1082-1088
2005
BRENDA: Cucumis sativus
Textmining: Electron
Garnczarska, M.
Response of the ascorbate-glutathione cycle to re-aeration following hypoxia in lupine roots
Plant Physiol. Biochem.
43
583-590
2005
BRENDA: Lupinus luteus
Textmining: Indicator
Sofo, A.; Tuzio, A.C.; Dichio, B.; Xiloyannis, C.
Influence of water deficit and rewatering on the components of the ascorbate-glutathione cycle in four interspecific Prunus hybrids
Plant Sci.
169
403-412
2005
Prunus sp.
Ali, M.B.; Yu, K.; Hahn, E.; Paek, K.
Differential responses of anti-oxidants enzymes, lipoxygenase activity, ascorbate content and the production of saponins in tissue cultured root of mountain Panax ginseng C.A. Mayer and Panax quinquefolium L. in bioreactor subjected to methyl jasmonate stress.
Plant Sci.
169
83-92
2005
Panax ginseng, Panax quinquefolius
Zou, L.; Li, H.; Ouyang, B.; Zhang, J.; Ye, Z.
Cloning and mapping of genes involved in tomato ascorbic acid biosynthesis and metabolism
Plant Sci.
170
120-127
2006
Solanum lycopersicum (Q4VDN7), Solanum lycopersicum (Q4VDN8)
Igamberdiev, A.U.; Stoimenova, M.; Seregelyes, C.; Hill, R.D.
Class-1 hemoglobin and antioxidant metabolism in alfalfa roots
Planta
223
1041-1046
2006
BRENDA: Medicago sativa
Textmining: plant
Shigenaga, T.; Yamauchi, N.; Funamoto, Y.; Shigyo, M.
Effects of heat treatment on an ascorbate-glutathione cycle in stored broccoli (Brassica oleracea L.) florets
Postharvest Biol. Technol.
38
152-159
2005
Brassica oleracea
-
Lai, Q.; Bao, Z.; Zhu, Z.; Mao, B.; Qian, Q.
Paraquat resistance in leaf discs of PSAG12-IPT modified gerbera is related to the activities of superoxide dismutase, catalase, and dehydroascorbate reductase
Agric. Sci. China
6
446-451
2007
Gerbera jamesonii
-
Chun, J.A.; Lee, W.H.; Han, M.O.; Lee, J.W.; Yi, Y.B.; Goo, Y.M.; Lee, S.W.; Bae, S.C.; Cho, K.J.; Chung, C.H.
Molecular and biochemical characterizations of dehydroascorbate reductase from sesame (Sesamum indicum L.) hairy root cultures
J. Agric. Food Chem.
55
6067-6073
2007
BRENDA: Sesamum indicum (A0S5Z5), Sesamum indicum
Textmining: Escherichia coli, Embryophyta, plant
Huang, G.J.; Lai, H.C.; Chang, Y.S.; Sheu, M.J.; Lu, T.L.; Huang, S.S.; Lin, Y.H.
Antimicrobial, dehydroascorbate reductase, and monodehydroascorbate reductase activities of defensin from sweet potato [Ipomoea batatas (L.) Lam. Tainong 57] storage roots
J. Agric. Food Chem.
56
2989-2995
2008
BRENDA: Ipomoea batatas (Q6Q8S2), Ipomoea batatas
Textmining: Bacteria, Escherichia coli, Fungi, plant
Jiang, Y.C.; Huang, C.Y.; Wen, L.; Lin, C.T.
Dehydroascorbate reductase cDNA from sweet potato (Ipomoea batatas [L.] Lam): expression, enzyme properties, and kinetic studies
J. Agric. Food Chem.
56
3623-3627
2008
Ipomoea batatas (D2CGD4), Ipomoea batatas
Loscos, J.; Matamoros, M.A.; Becana, M.
Ascorbate and homoglutathione metabolism in common bean nodules under stress conditions and during natural senescence
Plant Physiol.
146
1282-1292
2008
plant
Ding, S.; Lu, Q.; Zhang, Y.; Yang, Z.; Wen, X.; Zhang, L.; Lu, C.
Enhanced sensitivity to oxidative stress in transgenic tobacco plants with decreased glutathione reductase activity leads to a decrease in ascorbate pool and ascorbate redox state
Plant Mol. Biol.
69
577-592
2009
plant
Wan, Q.; Whang, I.; Lee, J.S.; Lee, J.
Novel omega glutathione S-transferases in disk abalone: Characterization and protective roles against environmental stress
Comp. Biochem. Physiol. C
150
558-568
2009
Haliotis corrugata, Haliotidae, Crassostrea gigas, Haliotis discus discus
Ken, C.F.; Lin, C.Y.; Jiang, Y.C.; Wen, L.; Lin, C.T.
Cloning, expression, and characterization of an enzyme possessing both glutaredoxin and dehydroascorbate reductase activity from Taiwanofungus camphorata
J. Agric. Food Chem.
57
10357-10362
2009
BRENDA: Taiwanofungus camphoratus
Textmining: Taiwanofungus, Escherichia coli
Kiraly, L.; Hafez, Y.M.; Fodor, J.; Kiraly, Z.
Suppression of tobacco mosaic virus-induced hypersensitive-type necrotization in tobacco at high temperature is associated with downregulation of NADPH oxidase and superoxide and stimulation of dehydroascorbate reductase
J. Gen. Virol.
89
799-808
2008
BRENDA: Nicotiana tabacum (Q84UH4), Nicotiana tabacum
Textmining: tobacco mosaic virus
Yang, H.L.; Zhao, Y.R.; Wang, C.L.; Yang, Z.L.; Zeng, Q.Y.; Lu, H.
Molecular characterization of a dehydroascorbate reductase from Pinus bungeana
J. Integr. Plant Biol.
51
993-1001
2009
BRENDA: Pinus bungeana (B2ZHM6), Pinus bungeana
Textmining: Arabidopsis, Embryophyta, Escherichia coli
Vadassery, J.; Tripathi, S.; Prasad, R.; Varma, A.; Oelmueller, R.
Monodehydroascorbate reductase 2 and dehydroascorbate reductase 5 are crucial for a mutualistic interaction between Piriformospora indica and Arabidopsis
J. Plant Physiol.
166
1263-1274
2009
BRENDA: Arabidopsis thaliana
Textmining: Arabidopsis, Serendipita indica, insertion sequences, Serendipita
Shin, S.Y.; Kim, I.S.; Kim, Y.H.; Park, H.M.; Lee, J.Y.; Kang, H.G.; Yoon, H.S.
Scavenging reactive oxygen species by rice dehydroascorbate reductase alleviates oxidative stresses in Escherichia coli
Mol. Cells
26
616-620
2008
BRENDA: Oryza sativa
Textmining: Escherichia coli, Escherichia coli BL21(DE3)
Eltelib, H.A.; Badejo, A.A.; Fujikawa, Y.; Esaka, M.
Gene expression of monodehydroascorbate reductase and dehydroascorbate reductase during fruit ripening and in response to environmental stresses in acerola (Malpighia glabra)
J. Plant Physiol.
168
619-627
2011
BRENDA: Malpighia glabra (E2RWY6), Malpighia glabra
Textmining: plant
Qin, A.; Shi, Q.; Yu, X.
Ascorbic acid contents in transgenic potato plants overexpressing two dehydroascorbate reductase genes
Mol. Biol. Rep.
38
1557-1566
2010
BRENDA: Solanum tuberosum
Textmining: Homo sapiens
Haghjou, M.M.; Shariati, M.; Smirnoff, N.
The effect of acute high light and low temperature stresses on the ascorbate-glutathione cycle and superoxide dismutase activity in two Dunaliella salina strains
Physiol. Plant.
135
272-280
2009
Dunaliella salina, Dunaliella
Bonsager, B.C.; Shahpiri, A.; Finnie, C.; Svensson, B.
Proteomic and activity profiles of ascorbate-glutathione cycle enzymes in germinating barley embryo
Phytochemistry
71
1650-1656
2010
Hordeum vulgare, Hordeum vulgare (O23983), Hordeum vulgare (Q945R5)
Yin, L.; Wang, S.; Eltayeb, A.E.; Uddin, M.I.; Yamamoto, Y.; Tsuji, W.; Takeuchi, Y.; Tanaka, K.
Overexpression of dehydroascorbate reductase, but not monodehydroascorbate reductase, confers tolerance to aluminum stress in transgenic tobacco
Planta
231
609-621
2010
BRENDA: Arabidopsis thaliana
Textmining: Nicotiana tabacum, Arabidopsis, plant
Hasanuzzaman, M.; Fujita, M.
Selenium pretreatment upregulates the antioxidant defense and methylglyoxal detoxification system and confers enhanced tolerance to drought stress in rapeseed seedlings
Biol. Trace Elem. Res.
143
1758-1776
2011
Felis catus
Osipova, S.; Permyakov, A.; Permyakova, M.; Pshenichnikova, T.; Brner, A.
Leaf dehydroascorbate reductase and catalase activity is associated with soil drought tolerance in bread wheat
Acta Physiol. Plant.
33
2169-2177
2011
Triticum aestivum
-
Zhou, H.; Brock, J.; Liu, D.; Board, P.G.; Oakley, A.J.
Structural insights into the dehydroascorbate reductase activity of human omega-class glutathione transferases
J. Mol. Biol.
420
190-203
2012
Homo sapiens (P78417), Homo sapiens (Q9H4Y5), Homo sapiens
Tang, Z.X.; Yang, H.L.
Functional divergence and catalytic properties of dehydroascorbate reductase family proteins from Populus tomentosa
Mol. Biol. Rep.
40
5105-5114
2013
BRENDA: Populus tomentosa (J9WN12), Populus tomentosa (J9WNR5), Populus tomentosa (J9WQY6), Populus tomentosa
Textmining: plant
Kim, Y.S.; Kim, I.S.; Bae, M.J.; Choe, Y.H.; Kim, Y.H.; Park, H.M.; Kang, H.G.; Yoon, H.S.
Homologous expression of cytosolic dehydroascorbate reductase increases grain yield and biomass under paddy field conditions in transgenic rice (Oryza sativa L. japonica)
Planta
237
1613-1625
2013
BRENDA: Oryza sativa
Textmining: Zea mays
Do, H.; Kim, I.S.; Kim, Y.S.; Shin, S.Y.; Kim, J.J.; Mok, J.E.; Park, S.I.; Wi, A.R.; Park, H.; Kim, H.W.; Yoon, H.S.; Lee, J.H.
Crystallization and preliminary X-ray crystallographic studies of dehydroascorbate reductase (DHAR) from Oryza sativa L. japonica
Acta Crystallogr. Sect. F
70
781-785
2014
BRENDA: Oryza sativa Japonica Group (Q65XA0)
Textmining: Lonicera japonica, Oryza sativa
Krishna Das, B.; Kumar, A.; Maindola, P.; Mahanty, S.; Jain, S.K.; Reddy, M.K.; Arockiasamy, A.
Non-native ligands define the active site of Pennisetum glaucum (L.) R. Br dehydroascorbate reductase
Biochem. Biophys. Res. Commun.
473
1152-1157
2016
BRENDA: Cenchrus americanus
Textmining: plant
Lallement, P.A.; Roret, T.; Tsan, P.; Gualberto, J.M.; Girardet, J.M.; Didierjean, C.; Rouhier, N.; Hecker, A.
Insights into ascorbate regeneration in plants investigating the redox and structural properties of dehydroascorbate reductases from Populus trichocarpa
Biochem. J.
473
717-731
2016
BRENDA: Populus trichocarpa
Textmining: Populus
Noshi, M.; Hatanaka, R.; Tanabe, N.; Terai, Y.; Maruta, T.; Shigeoka, S.
Redox regulation of ascorbate and glutathione by a chloroplastic dehydroascorbate reductase is required for high-light stress tolerance in Arabidopsis
Biosci. Biotechnol. Biochem.
80
870-877
2016
BRENDA: Arabidopsis thaliana
Textmining: Arabidopsis
Noshi, M.; Yamada, H.; Hatanaka, R.; Tanabe, N.; Tamoi, M.; Shigeoka, S.
Arabidopsis dehydroascorbate reductase 1 and 2 modulate redox states of ascorbate-glutathione cycle in the cytosol in response to photooxidative stress
Biosci. Biotechnol. Biochem.
81
523-533
2017
BRENDA: Arabidopsis thaliana
Textmining: Arabidopsis
Huang, G.; Deng, J.; Chen, H.; Huang, S.; Shih, C.; Lin, Y.
Dehydroascorbate reductase and monodehydroascorbate reductase activities of two metallothionein-like proteins from sweet potato (Ipomoea batatas [L.] Lam. Tainong 57) storage roots
Bot. Stud.
54
007
2013
Ipomoea batatas (B6VJL9), Ipomoea batatas (Q9ZSC6), Ipomoea batatas, Escherichia coli, plant
Huang, G.J.; Deng, J.S.; Chen, H.J.; Huang, S.S.; Shih, C.C.; Lin, Y.H.
Dehydroascorbate reductase and monodehydroascorbate reductase activities of two metallothionein-like proteins from sweet potato (Ipomoea batatas [L.] Lam. Tainong 57) storage roots
Bot. Stud.
54
7-7
2013
BRENDA: Ipomoea batatas
Textmining: Escherichia coli, plant
Chang, L.; Sun, H.; Yang, H.; Wang, X.; Su, Z.; Chen, F.; Wei, W.
Over-expression of dehydroascorbate reductase enhances oxidative stress tolerance in tobacco
Electron. J. Biotechnol.
25
1-8
2017
Jatropha curcas (R9QAK3)
-
Li, R.; Xin, S.; Tao, C.; Jin, X.; Li, H.
Cotton ascorbate oxidase promotes cell growth in cultured tobacco bright Yellow-2 cells through generation of apoplast oxidation
Int. J. Mol. Sci.
18
1346
2017
Nicotiana tabacum
Kim, Y.; Kim, I.; Shin, S.; Park, T.; Park, H.; Kim, Y.; Lee, G.; Kang, H.; Lee, S.; Yoon, H.
Overexpression of dehydroascorbate reductase confers enhanced tolerance to salt stress in rice plants (Oryza sativa L. japonica)
J. Agron. Crop Sci.
200
444-456
2014
Oryza sativa Japonica Group (Q65XA0)
-
Han, E.; Goo, Y.; Kim, Y.; Lee, S.
Proteomic analysis of dehydroascorbate reductase transgenic potato plants
J. Plant Biotechnol.
43
223-230
2016
Sesamum indicum
-
Shin, S.Y.; Kim, M.H.; Kim, Y.H.; Park, H.M.; Yoon, H.S.
Co-expression of monodehydroascorbate reductase and dehydroascorbate reductase from Brassica rapa effectively confers tolerance to freezing-induced oxidative stress
Mol. Cells
36
304-315
2013
BRENDA: Brassica rapa
Textmining: plant
Xue, Y.; Miyakawa, T.; Nakamura, A.; Hatano, K.; Sawano, Y.; Tanokura, M.
Yam tuber storage protein reduces plant oxidants using the coupled reactions as carbonic anhydrase and dehydroascorbate reductase
Mol. Plant
8
1115-1118
2015
Dioscorea japonica
Lin, S.T.; Chiou, C.W.; Chu, Y.L.; Hsiao, Y.; Tseng, Y.F.; Chen, Y.C.; Chen, H.J.; Chang, H.Y.; Lee, T.M.
Enhanced ascorbate regeneration via dehydroascorbate reductase confers tolerance to photo-oxidative stress in Chlamydomonas reinhardtii
Plant Cell Physiol.
57
2104-2121
2016
Chlamydomonas reinhardtii (A8I0K9), Chlamydomonas reinhardtii
Pandey, P.; Achary, V.M.; Kalasamudramu, V.; Mahanty, S.; Reddy, G.M.; Reddy, M.K.
Molecular and biochemical characterization of dehydroascorbate reductase from a stress adapted C4 plant, pearl millet [Pennisetum glaucum (L.) R. Br]
Plant Cell Rep.
33
435-445
2014
BRENDA: Cenchrus americanus (U5XYA0), Cenchrus americanus
Textmining: plant
Liu, F.; Guo, X.; Yao, Y.; Tang, W.; Zhang, W.; Cao, S.; Han, Y.; Liu, Y.
Cloning and function characterization of two dehydroascorbate reductases from kiwifruit (Actinidia chinensis L.)
Plant Mol. Biol. Rep.
34
815-826
2016
Actinidia chinensis
-
Zhang, Y.J.; Wang, W.; Yang, H.L.; Li, Y.; Kang, X.Y.; Wang, X.R.; Yang, Z.L.
Molecular Properties and functional divergence of the dehydroascorbate reductase gene family in lower and higher plants
PLoS ONE
10
e0145038
2015
BRENDA: Arabidopsis thaliana (Q9FWR4), Brachypodium distachyon, Picea abies, Pinus taeda, Populus trichocarpa, Selaginella moellendorffii, Zea mays
Textmining: Arabidopsis, Embryophyta, eudicotyledons, Marchantiophyta, plant
Do, H.; Kim, I.S.; Jeon, B.W.; Lee, C.W.; Park, A.K.; Wi, A.R.; Shin, S.C.; Park, H.; Kim, Y.S.; Yoon, H.S.; Kim, H.W.; Lee, J.H.
Structural understanding of the recycling of oxidized ascorbate by dehydroascorbate reductase (OsDHAR) from Oryza sativa L. japonica
Sci. Rep.
6
19498
2016
BRENDA: Oryza sativa Japonica Group (Q65XA0)
Textmining: Oryza sativa, Lonicera japonica, Electron
Bodra, N.; Young, D.; Astolfi Rosado, L.; Pallo, A.; Wahni, K.; De Proft, F.; Huang, J.; Van Breusegem, F.; Messens, J.
Arabidopsis thaliana dehydroascorbate reductase 2 Conformational flexibility during catalysis
Sci. Rep.
7
42494
2017
BRENDA: Arabidopsis thaliana
Textmining: plant
Rahman, A.; Mostofa, M.G.; Alam, M.M.; Nahar, K.; Hasanuzzaman, M.; Fujita, M.
Calcium mitigates arsenic toxicity in rice seedlings by reducing arsenic uptake and modulating the antioxidant defense and glyoxalase systems and stress markers
BioMed Res. Int.
2015
340812
2015
Oryza sativa
Zhuge, X.L.; Xu, H.; Xiu, Z.J.; Yang, H.L.
Biochemical functions of glutathione S-transferase family of Salix babylonica
Front. Plant Sci.
11
364
2020
Salix babylonica, Salix babylonica (A0A4Y5QZW9), Salix babylonica (A0A4Y5QZX0), Salix babylonica (A0A4Y5QZX2), Salix babylonica (A0A4Y5QZX3), Salix babylonica (A0A4Y5QZX9), Salix babylonica (A0A4Y5QZZ8), Salix babylonica (A0A4Y5R032), Salix babylonica (A0A4Y5R087), Salix babylonica (A0A4Y5R0B2), Salix babylonica (A0A4Y5R0C1), Salix babylonica (A0A4Y5R0K8), Salix babylonica (A0A4Y5R0L5), Salix babylonica (A0A4Y5R2M7), Salix babylonica (A0A4Y5R2N2)
Gao, X.-H.; Zaffagnini, M.; Bedhomme, M.; Michelet, L.; Cassier-Chauvat, C.; Decottignies, P.; Lemaire, S.D.
Biochemical characterization of glutaredoxins from Chlamydomonas reinhardtii kinetics and specificity in deglutathionylation reactions
FEBS Lett.
584
2242-2248
2010
Chlamydomonas reinhardtii (A8IYH1), Chlamydomonas reinhardtii (A8JHA9)
Zaffagnini, M.; Michelet, L.; Massot, V.; Trost, P.; Lemaire, S.D.
Biochemical characterization of glutaredoxins from Chlamydomonas reinhardtii reveals the unique properties of a chloroplastic CGFS-type glutaredoxin
J. Biol. Chem.
283
8868-8876
2008
BRENDA: Chlamydomonas reinhardtii (A8JHA9), Chlamydomonas reinhardtii
Textmining: Chlamydomonas, Embryophyta, Electron
Jiang, Z.Y.; Zhong, Y.; Zheng, J.; Ali, M.; Liu, G.D.; Zheng, X.L.
L-ascorbic acid metabolism in an ascorbate-rich kiwifruit (Actinidia eriantha Benth.) cv. White during postharvest
Plant Physiol. Biochem.
124
20-28
2018
Actinidia deliciosa
Choudhury, S.; Moulick, D.; Mazumder, M.
Secondary metabolites protect against metal and metalloid stress in rice an in silico investigation using dehydroascorbate reductase
Acta Physiol. Plant.
43
3
2021
Oryza sativa Japonica Group (Q65XA0)
-
Loi, M.; Leonardis, S.; Mul, G.; Logrieco, A.; Paciolla, C.
A novel and potentially multifaceted dehydroascorbate reductase increasing the antioxidant systems is induced by beauvericin in tomato
Antioxidants (Basel)
9
435
2020
BRENDA: Solanum lycopersicum (Q4VDN8), Solanum lycopersicum
Textmining: Electron
Saruta, F.; Yamada, N.; Yamamoto, K.
An omega-class glutathione S-transferase in the brown planthopper Nilaparvata lugens exhibits glutathione transferase and dehydroascorbate reductase activities
Arch. Insect Biochem. Physiol.
102
e21599
2019
BRENDA: Nilaparvata lugens (J9Q3Y4), Nilaparvata lugens
Textmining: Escherichia coli
Ding, H.; Wang, B.; Han, Y.; Li, S.
The pivotal function of dehydroascorbate reductase in glutathione homeostasis in plants
J. Exp. Bot.
71
3405-3416
2020
BRENDA: Acer saccharinum, Actinidia chinensis, Avena sativa, Brassica napus, Hordeum vulgare, Pisum sativum, Populus trichocarpa, Populus trichocarpa (D2WL73), Populus trichocarpa (D2WL74), Populus trichocarpa (D2WL75), Liriodendron chinense (A0A6C0W973), Pinus bungeana (B2ZHM6), Zea mays (C0P9V2), Ipomoea batatas (D2CGD4), Populus tomentosa (J9WN12), Populus tomentosa (J9WNR5), Populus tomentosa (J9WQY6), Solanum tuberosum (M1BA41), Oryza sativa Japonica Group (Q65XA0), Arabidopsis thaliana (Q8LE52), Arabidopsis thaliana (Q9FRL8), Arabidopsis thaliana (Q9FWR4), Spinacia oleracea (Q9T2H6), Cenchrus americanus (U5XYA0), Arabidopsis thaliana Col-0 (Q9FWR4)
Textmining: Arabidopsis, plant
Dell'Aglio, L.; Mhamdi, A.
What are the roles for dehydroascorbate reductases and glutathione in sustaining ascorbate accumulation?
Plant Physiol.
183
11-12
2020
Nicotiana benthamiana, Zea mays (C0P9V2), Arabidopsis thaliana (Q8LE52), Arabidopsis thaliana (Q9FRL8), Arabidopsis thaliana (Q9FWR4)
Terai, Y.; Ueno, H.; Ogawa, T.; Sawa, Y.; Miyagi, A.; Kawai-Yamada, M.; Ishikawa, T.; Maruta, T.
Dehydroascorbate reductases and glutathione set a threshold for high-light-induced ascorbate accumulation
Plant Physiol.
183
112-122
2020
BRENDA: Arabidopsis thaliana (Q8LE52), Arabidopsis thaliana (Q9FRL8), Arabidopsis thaliana (Q9FWR4), Arabidopsis thaliana Col-0 (Q8LE52), Arabidopsis thaliana Col-0 (Q9FRL8), Arabidopsis thaliana Col-0 (Q9FWR4)
Textmining: Arabidopsis
Chang, H.Y.; Lin, S.T.; Ko, T.P.; Wu, S.M.; Lin, T.H.; Chang, Y.C.; Huang, K.F.; Lee, T.M.
Enzymatic characterization and crystal structure analysis of Chlamydomonas reinhardtii dehydroascorbate reductase and their implications for oxidative stress
Plant Physiol. Biochem.
120
144-155
2017
Chlamydomonas reinhardtii (A8I0K9), Chlamydomonas reinhardtii
Rahantaniaina, M.S.; Li, S.; Chatel-Innocenti, G.; Tuzet, A.; Mhamdi, A.; Vanacker, H.; Noctor, G.
Glutathione oxidation in response to intracellular H2O2 key but overlapping roles for dehydroascorbate reductases
Plant Signal. Behav.
12
e1356531
2017
Arabidopsis thaliana (Q8LE52), Arabidopsis thaliana (Q9FRL8), Arabidopsis thaliana (Q9FWR4), Arabidopsis thaliana Col-0 (Q8LE52), Arabidopsis thaliana Col-0 (Q9FRL8), Arabidopsis thaliana Col-0 (Q9FWR4)
Wu, B.; Wang, B.
Comparative analysis of ascorbate peroxidases (APXs) from selected plants with a special focus on Oryza sativa employing public databases
PLoS ONE
14
e0226543
2019
Oryza sativa, plant
Kuo, E.Y.; Cai, M.S.; Lee, T.M.
Ascorbate peroxidase 4 plays a role in the tolerance of Chlamydomonas reinhardtii to photo-oxidative stress
Sci. Rep.
10
13287
2020
Chlamydomonas
Miyayama, T; Arai, Y; Suzuki, N; Hirano, S
Mitochondrial electron transport is inhibited by disappearance of metallothionein in human bronchial epithelial cells following exposure to silver nitrate.
Toxicology
305
20-9
2013
Homo sapiens
Kochi, H; Serizawa, K; Kikuchi, G
On the nature of three forms of phosphoenolpyruvate carboxykinase occurring in the cytosol of chicken liver.
J Biochem (Tokyo)
88
895-904
1980
Oryctolagus cuniculus
Hou, WC; Liu, JS; Chen, HJ; Chen, TE; Chang, CF; Lin, YH
Dioscorin, the major tuber storage protein of yam (Dioscorea batatas decne) with carbonic anhydrase and trypsin inhibitor activities.
J Agric Food Chem
47
2168-72
1999
Tuber, Dioscorea alata
Xue, YL; Miyakawa, T; Nakamura, A; Hatano, KI; Sawano, Y; Tanokura, M
Yam tuber storage protein reduces plant oxidants using the coupled reactions as carbonic anhydrase and dehydroascorbate reductase.
Mol Plant
2015
Tuber, Dioscorea alata, plant
Perkins, SN; Eipper, BA; Mains, RE
Stable expression of full-length and truncated bovine peptidylglycine alpha-amidating monooxygenase complementary DNAs in cultured cells.
Mol Endocrinol
4
132-9
1990
Mus musculus
Lin, YS; Han, CH; Lin, SY; Hou, WC
Synthesized Peptides from Yam Dioscorin Hydrolysis in Silico Exhibit Dipeptidyl Peptidase-IV Inhibitory Activities and Oral Glucose Tolerance Improvements in Normal Mice.
J Agric Food Chem
64
6451-8
2016
Mus sp., Dioscorea alata, animal
Han, CH; Liu, JC; Fang, SU; Hou, WC
Antioxidant activities of the synthesized thiol-contained peptides derived from computer-aided pepsin hydrolysis of yam tuber storage protein, dioscorin.
Food Chem
138
923-30
2013
Tuber, Dioscorea alata, Electron
Lin, YS; Lu, YL; Wang, GJ; Liang, HJ; Hou, WC
Vasorelaxing and antihypertensive activities of synthesized peptides derived from computer-aided simulation of pepsin hydrolysis of yam dioscorin.
Bot Stud
55
49
2014
Dioscorea alata
Hsu, FL; Lin, YH; Lee, MH; Lin, CL; Hou, WC
Both dioscorin, the tuber storage protein of yam (Dioscorea alata cv. Tainong No. 1), and its peptic hydrolysates exhibited angiotensin converting enzyme inhibitory activities.
J Agric Food Chem
50
6109-13
2002
Tuber, Dioscorea alata, Homo sapiens
Trümper, S; Follmann, H; Häberlein, I
A novel-dehydroascorbate reductase from spinach chloroplasts homologous to plant trypsin inhibitor.
FEBS Lett
352
159-62
1994
Spinacia oleracea, Glycine max, plant
Hou, WC; Wang, YT; Lin, YH; Hsiao, LJ; Chen, TE; Wang, CW; Dai, H
A complex containing both trypsin inhibitor and dehydroascorbate reductase activities isolated from mitochondria of etiolated mung bean (Vigna radiata L. (Wilczek) cv. Tainan no. 5) seedlings.
J Exp Bot
51
713-9
2000
Vigna radiata var. radiata, Ipomoea batatas
Kao W;Chang C;Lin K
Antioxidant and trypsin inhibition activity of dioscorin influenced by yam cultivars and eluent pH
International journal of food science and technology.
47
1384-1391
2012
Dioscorea alata
Cristina Giannotti, K; Leiguez, E; Moreira, V; Nascimento, NG; Lomonte, B; Gutirrez, JM; Lopes de Melo, R; Teixeira, C
A Lys49 Phospholipase A2, Isolated from Bothrops asper Snake Venom, Induces Lipid Droplet Formation in Macrophages Which Depends on Distinct Signaling Pathways and the C-Terminal Region.
Biomed Res Int
2013
807982
2013
Bothrops asper
Fernndez, J; Caccin, P; Koster, G; Lomonte, B; Gutirrez, JM; Montecucco, C; Postle, AD
Muscle phospholipid hydrolysis by Bothrops asper Asp49 and Lys49 phospholipase A2 myotoxins--distinct mechanisms of action.
FEBS J
280
3878-86
2013
Mus musculus
Brenes, H; Lora, GD; Lomonte, B
Potent virucidal activity against Flaviviridae of a group IIA phospholipase A2 isolated from the venom of Bothrops asper.
Biologicals
63
48-52
2020
Bothrops asper, Dengue virus, Viruses
Paulus, W; Baur, I; Oberer, DM; Breakefield, XO; Reeves, SA
Regulated expression of the diphtheria toxin A gene in human glioma cells using prokaryotic transcriptional control elements.
J Neurosurg
87
89-95
1997
Mus musculus
Lachke, SA; Srikantha, T; Tsai, LK; Daniels, K; Soll, DR
Phenotypic switching in Candida glabrata involves phase-specific regulation of the metallothionein gene MT-II and the newly discovered hemolysin gene HLP.
Infect Immun
68
884-95
2000
[Candida] glabrata
Abe, T; Yamamura, K; Gotoh, S; Kashimura, M; Higashi, K
Concentration-dependent differential effects of N-acetyl-L-cysteine on the expression of HSP70 and metallothionein genes induced by cadmium in human amniotic cells.
Biochim Biophys Acta
1380
123-32
1998
Homo sapiens
DiMeglio, LM; Staudt, G; Yu, H; Davis, TM
A phylogenetic analysis of the genus Fragaria (strawberry) using intron-containing sequence from the ADH-1 gene.
PLoS One
9
e102237
2014
Fragaria vesca
[Glutathione-dependent enzymes and glucose-6-phosphate dehydrogenase of blood in patients with lymphosarcoma (non-Hodgkin's disease)].
Biomed Khim
57
225-31
0
Homo sapiens
Li, C; Wei, M; Ge, Y; Zhao, J; Chen, Y; Hou, J; Cheng, Y; Chen, J; Li, J
The role of glucose-6-phosphate dehydrogenase in reactive oxygen species metabolism in apple exocarp induced by acibenzolar-S-methyl.
Food Chem
308
125663
2020
Malus domestica, Felis catus
Barros, MP; Bechara, EJ
Daily variations of antioxidant enzyme and luciferase activities in the luminescent click-beetle Pyrearinus termitilluminans: cooperation against oxygen toxicity.
Insect Biochem Mol Biol
31
393-400
2001
Pyrearinus termitilluminans, Bacteria, Coleoptera
Del Bello, B; Maellaro, E; Sugherini, L; Santucci, A; Comporti, M; Casini, AF
Purification of NADPH-dependent dehydroascorbate reductase from rat liver and its identification with 3 alpha-hydroxysteroid dehydrogenase.
Biochem J
304 ( Pt 2)
385-90
1994
Rattus
Li, Y; Yokoi, T; Kitamura, R; Sasaki, M; Gunji, M; Katsuki, M; Kamataki, T
Establishment of transgenic mice carrying human fetus-specific CYP3A7.
Arch Biochem Biophys
329
235-240
1996
Homo sapiens, Mus musculus, Mus sp.
Kingston-Smith, AH; Foyer, CH
Overexpression of Mn-superoxide dismutase in maize leaves leads to increased monodehydroascorbate reductase, dehydroascorbate reductase and glutathione reductase activities.
J Exp Bot
51
1867-77
2000
Zea mays
Haroldsen, VM; Chi-Ham, CL; Kulkarni, S; Lorence, A; Bennett, AB
Constitutively expressed DHAR and MDHAR influence fruit, but not foliar ascorbate levels in tomato.
Plant Physiol Biochem
2011
Homo sapiens, plant, Solanum lycopersicum
Zhang, Y; Li, Z; Peng, Y; Wang, X; Peng, D; Li, Y; He, X; Zhang, X; Ma, X; Huang, L; Yan, Y
Clones of FeSOD, MDHAR, DHAR Genes from White Clover and Gene Expression Analysis of ROS-Scavenging Enzymes during Abiotic Stress and Hormone Treatments.
Molecules
20
20939-54
2015
Trifolium repens
Cui, L; Takagi, Y; Wasa, M; Iiboshi, Y; Khan, J; Nezu, R; Okada, A
Induction of nitric oxide synthase in rat intestine by interleukin-1alpha may explain diarrhea associated with zinc deficiency.
J Nutr
127
1729-36
1997
Rattus
Cui, L; Takagi, Y; Wasa, M; Sando, K; Khan, J; Okada, A
Nitric oxide synthase inhibitor attenuates intestinal damage induced by zinc deficiency in rats.
J Nutr
129
792-8
1999
Rattus
Braun, W; Vasák, M; Robbins, AH; Stout, CD; Wagner, G; Kägi, JH; Wüthrich, K
Comparison of the NMR solution structure and the x-ray crystal structure of rat metallothionein-2.
Proc Natl Acad Sci U S A
89
10124-8
1992
Rattus
Ahn, BY; Moss, B
Glutaredoxin homolog encoded by vaccinia virus is a virion-associated enzyme with thioltransferase and dehydroascorbate reductase activities.
Proc Natl Acad Sci U S A
89
7060-4
1992
Vaccinia virus, Escherichia coli, Bacteria, eukaryota
Séguin, C
A nuclear factor requires Zn2+ to bind a regulatory MRE element of the mouse gene encoding metallothionein-1.
Gene
97
295-300
1991
Mus musculus
Messerle, BA; Bos, M; Schäffer, A; Vasák, M; Kägi, JH; Wüthrich, K
Amide proton exchange in human metallothionein-2 measured by nuclear magnetic resonance spectroscopy.
J Mol Biol
214
781-6
1990
Homo sapiens
Wetzel, A; Werner, D
Quinoline increases ascorbate peroxidase and dehydroascorbate reductase activity in Vicia faba nodules.
Bull Environ Contam Toxicol
45
619-26
1990
Vicia faba
Koropatnick, J; Winning, R; Wiese, E; Heschl, M; Gedamu, L; Duerksen, J
Acute treatment of mice with cadmium salts results in amplification of the metallothionein-1 gene in liver.
Nucleic Acids Res
13
5423-39
1985
Mus sp., Mus musculus
Koropatnick, J; Duerksen, JD
Nuclease sensitivity of alpha-fetoprotein, metallothionein-1, and immunoglobulin gene sequences in mouse during development.
Dev Biol
122
1-10
1987
Mus musculus
Koropatnick, J
Amplification of metallothionein-1 genes in mouse liver cells in situ: extra copies are transcriptionally active.
Proc Soc Exp Biol Med
188
287-300
1988
Mus musculus, Mus sp.
Miller, KF; Bolt, DJ; Pursel, VG; Hammer, RE; Pinkert, CA; Palmiter, RD; Brinster, RL
Expression of human or bovine growth hormone gene with a mouse metallothionein-1 promoter in transgenic swine alters the secretion of porcine growth hormone and insulin-like growth factor-I.
J Endocrinol
120
481-8
1989
Homo sapiens, Sus scrofa, Bos taurus, Mus musculus
Wagner, G; Frey, MH; Neuhaus, D; Wörgötter, E; Braun, W; Vasak, M; Kägi, JH; Wüthrich, K
Spatial structure of rabbit liver metallothionein-2 in solution by NMR.
Experientia Suppl
52
149-57
1987
Oryctolagus cuniculus
Neuhaus, D; Wagner, G; Vasák, M; Kägi, JH; Wüthrich, K
Systematic application of high-resolution, phase-sensitive two-dimensional 1H-NMR techniques for the identification of the amino-acid-proton spin systems in proteins. Rabbit metallothionein-2.
Eur J Biochem
151
257-73
1985
Oryctolagus cuniculus
Andersen, RD; Birren, BW; Taplitz, SJ; Herschman, HR
Rat metallothionein-1 structural gene and three pseudogenes, one of which contains 5'-regulatory sequences.
Mol Cell Biol
6
302-14
1986
Rattus
Bogdanova, IA; Gerasimov, AM; Komarov, OS
[Glutathione:dehydroascorbate oxidoreductase activity in rabbit eye tissues]
Vopr Med Khim
33
104-7
0
Oryctolagus cuniculus
Vasák, M; Wörgötter, E; Wagner, G; Kägi, JH; Wüthrich, K
Metal co-ordination in rat liver metallothionein-2 prepared with or without reconstitution of the metal clusters, and comparison with rabbit liver metallothionein-2.
J Mol Biol
196
711-9
1987
Oryctolagus cuniculus, Rattus
Wagner, G; Neuhaus, D; Wörgötter, E; Vasák, M; Kägi, JH; Wüthrich, K
Nuclear magnetic resonance identification of "half-turn" and 3(10)-helix secondary structure in rabbit liver metallothionein-2.
J Mol Biol
187
131-5
1986
Oryctolagus cuniculus
Gero, E; Candido, A
[Determination of the molecular weight of dehydroascorbic reductase from cauliflower by filtration on Sephadex G 100]
Bull Soc Chim Biol (Paris)
51
194-6
1969
Brassica oleracea var. botrytis
Gero, E; Candido, A
[Purification of dehydroascorbic reductase of cauliflower (Brassica oleracea L.)]
Bull Soc Chim Biol (Paris)
49
1895-7
1967
Brassica oleracea var. botrytis
Varshney, U; Gedamu, L
Human metallothionein MT-I and MT-II processed genes.
Gene
31
135-45
1984
Homo sapiens
Singh, SP; Sidhu, LS
Pubertal development of Gaddi Rajput boys of Dhaula Dhar Range of the Himalayas.
Z Morphol Anthropol
72
89-98
1981
Homo sapiens
Singh, SP; Sidhu, LS
Physical growth of Gaddi Rajput boys of Dhaula Dhar Range of the Himalayas. II. Extremities.
Z Morphol Anthropol
72
113-26
1981
Homo sapiens
Akintola, DF; Sampson, B; Fleck, A
Development of an enzyme-linked immunosorbent assay for human metallothionein-1 in plasma and urine.
J Lab Clin Med
126
119-27
1995
Homo sapiens
Rose, C; Devamanoharan, PS; Varma, SD
Dehydroascorbate reductase activity in bovine lens.
Int J Vitam Nutr Res
65
40-4
1995
Bos taurus
Narula, SS; Brouwer, M; Hua, Y; Armitage, IM
Three-dimensional solution structure of Callinectes sapidus metallothionein-1 determined by homonuclear and heteronuclear magnetic resonance spectroscopy.
Biochemistry
34
620-31
1995
Callinectes sapidus
Clark, D; Albrecht, M; Arévalo, J
Ascorbate variations and dehydroascorbate reductase activity in Trypanosoma cruzi epimastigotes and trypomastigotes.
Mol Biochem Parasitol
66
143-5
1994
Trypanosoma cruzi
Maellaro, E; Del Bello, B; Sugherini, L; Santucci, A; Comporti, M; Casini, AF
Purification and characterization of glutathione-dependent dehydroascorbate reductase from rat liver.
Biochem J
301 ( Pt 2)
471-6
1994
Rattus
Zhu, Z; DeRose, EF; Mullen, GP; Petering, DH; Shaw, CF
Sequential proton resonance assignments and metal cluster topology of lobster metallothionein-1.
Biochemistry
33
8858-65
1994
Lobster
Summers, CB; Felton, GW
Antioxidant role of dehydroascorbic acid reductase in insects.
Biochim Biophys Acta
1156
235-8
1993
Hexapoda
Saito, S; Hunziker, PE
Differential sensitivity of metallothionein-1 and -2 in liver of zinc-injected rat toward proteolysis.
Biochim Biophys Acta
1289
65-70
1996
Rattus
Odawara, F; Kurasaki, M; Suzuki-Kurasaki, M; Oikawa, S; Emoto, T; Yamasaki, F; Linde Arias, AR; Kojima, Y
Expression of human metallothionein-2 in Escherichia coli: cadmium tolerance of transformed cells.
J Biochem (Tokyo)
118
1131-7
1995
Escherichia coli, Homo sapiens
Tommasi, F; Paciolla, C; D'Elia, F; Arrigoni, O
Changes of ascorbate peroxidase and dehydroascorbate reductase activities during seed development of Vicia faba L.
Boll Soc Ital Biol Sper
71
341-6
0
Vicia faba
Krafchik, BR
Commentary on Nagaraja, Kanwar, Dhar, and Singh: frequency and significance of minor clinical features in various age-related subgroups of atopic dermatitis in children.
Pediatr Dermatol
13
61-2
0
Homo sapiens
Beattie, JH; Black, DJ; Wood, AM; Trayhurn, P
Cold-induced expression of the metallothionein-1 gene in brown adipose tissue of rats.
Am J Physiol
270
R971-7
1996
Rattus
Akintola, DF; Sampson, B; Burrin, J; Fleck, A; Price, C; Hall, G
Changes in plasma metallothionein-1, interleukin-6, and C-reactive protein in patients after elective surgery.
Clin Chem
43
845-7
1997
Homo sapiens
Foyer, CH; Mullineaux, PM
The presence of dehydroascorbate and dehydroascorbate reductase in plant tissues.
FEBS Lett
425
528-9
1998
plant
Cui, L; Takagi, Y; Wasa, M; Iiboshi, Y; Inoue, M; Khan, J; Sando, K; Nezu, R; Okada, A
Zinc deficiency enhances interleukin-1alpha-induced metallothionein-1 expression in rats.
J Nutr
128
1092-8
1998
Rattus
Ishikawa, T; Casini, AF; Nishikimi, M
Molecular cloning and functional expression of rat liver glutathione-dependent dehydroascorbate reductase.
J Biol Chem
273
28708-12
1998
Rattus, Cricetulus griseus
Washburn, MP; Wells, WW
Identification of the dehydroascorbic acid reductase and thioltransferase (Glutaredoxin) activities of bovine erythrocyte glutathione peroxidase.
Biochem Biophys Res Commun
257
567-71
1999
Bos taurus
Beattie, JH; Wood, AM; Duncan, GJ
Rat metallothionein-2 contains N(alpha)-acetylated and unacetylated isoforms.
Electrophoresis
20
1613-8
1999
Rattus
Zhang, XT; YU, DM; WU, HL
[Targeting of MT-II gene in mouse ES cells]
Yi Chuan Xue Bao
25
491-8
1998
Mus musculus
Pan, PK; Zheng, ZF; Lyu, PC; Huang, PC
Why reversing the sequence of the alpha domain of human metallothionein-2 does not change its metal-binding and folding characteristics.
Eur J Biochem
266
33-9
1999
Homo sapiens
Urano, J; Nakagawa, T; Maki, Y; Masumura, T; Tanaka, K; Murata, N; Ushimaru, T
Molecular cloning and characterization of a rice dehydroascorbate reductase.
FEBS Lett
466
107-11
2000
Oryza sativa, Rattus, plant, Escherichia coli
Aoyama, Y; Kato, C
Suppressive effect of excess dietary histidine on the expression of hepatic metallothionein-1 in rats.
Biosci Biotechnol Biochem
64
588-91
2000
Rattus
Akatsuka, I; Bando, M; Obazawa, H; Oka, M; Takehana, M; Kobayashi, S
NADH-dependent dehydroascorbate reductase in the rabbit lens.
Tokai J Exp Clin Med
26
25-32
2001
Oryctolagus cuniculus
Hou, WC; Lee, MH; Chen, HJ; Liang, WL; Han, CH; Liu, YW; Lin, YH
Antioxidant activities of dioscorin, the storage protein of yam (Dioscorea batatas Decne) tuber.
J Agric Food Chem
49
4956-60
2001
Dioscorea, Dioscorea alata, Electron, Homo sapiens, Tuber
Vemulapalli, R; Kurowski, S; Salisbury, B; Parker, E; Davis, H
Activation of central melanocortin receptors by MT-II increases cavernosal pressure in rabbits by the neuronal release of NO.
Br J Pharmacol
134
1705-10
2001
Oryctolagus cuniculus
Yu, WH; Cai, B; Gao, Y; Xie, Y; Huang, ZX
Expression, characterization, and reaction of recombinant monkey metallothionein-1 and its C33M mutant.
J Protein Chem
21
177-85
2002
Platyrrhini
Toyama, M; Yamashita, M; Hirayama, N; Murooka, Y
Interactions of arsenic with human metallothionein-2.
J Biochem (Tokyo)
132
217-21
2002
Homo sapiens
Muñoz, A; Försterling, FH; Shaw, CF; Petering, DH
Structure of the (113)Cd(3)beta domains from Homarus americanus metallothionein-1: hydrogen bonding and solvent accessibility of sulfur atoms.
J Biol Inorg Chem
7
713-24
2002
Homarus americanus
Huang, ZX; Gao, Y; Yu, WH; Zhang, SY; Yang, PY
Construction of alpha-alpha domains structure in recombinant monkey metallothionein-1.
J Inorg Biochem
92
183-92
2002
Platyrrhini
Espey, LL; Ujioka, T; Okamura, H; Richards, JS
Metallothionein-1 messenger RNA transcription in steroid-secreting cells of the rat ovary during the periovulatory period.
Biol Reprod
68
1895-902
2003
Rattus
Santon, A; Sturniolo, GC; Albergoni, V; Irato, P
Metallothionein-1 and metallothionein-2 gene expression and localisation of apoptotic cells in Zn-treated LEC rat liver.
Histochem Cell Biol
119
301-8
2003
Rattus
Kwon, SY; Choi, SM; Ahn, YO; Lee, HS; Lee, HB; Park, YM; Kwak, SS
Enhanced stress-tolerance of transgenic tobacco plants expressing a human dehydroascorbate reductase gene.
J Plant Physiol
160
347-53
2003
Nicotiana tabacum, Homo sapiens
Trivedi, P; Jiang, M; Tamvakopoulos, CC; Shen, X; Yu, H; Mock, S; Fenyk-Melody, J; Van der Ploeg, LH; Guan, XM
Exploring the site of anorectic action of peripherally administered synthetic melanocortin peptide MT-II in rats.
Brain Res
977
221-30
2003
Rattus, Rodentia
Suzuki, T; Bando, M; Oka, M; Tsukamoto, H; Akatsuka, I; Kawai, K; Obazawa, H; Kobayashi, S; Takehana, M
lambda-crystallin related to dehydroascorbate reductase in the rabbit lens.
Jpn J Ophthalmol
47
437-43
0
Oryctolagus cuniculus
YAMAGUCHI, M; JOSLYN, MA
Purification and properties of dehydroascorbic acid reductase of peas (Pisum sativum).
Arch Biochem Biophys
38
451-65
1952
Pisum sativum
Bruschi, F; Saviozzi, M; Piaggi, S; Malvaldi, G; Casini, A
Up-regulation of the 31 kDa dehydroascorbate reductase in the modified skeletal muscle cell (nurse cell) during Trichinella spp. infection.
Int J Parasitol
33
1035-42
2003
Homo sapiens, Metazoa, Rattus, Trichinella, Trichinella spiralis
BAHADUR, K
A study of the changes in the physiological properties of Dhar yeast by growing it in cultures containing sucrose, ethyl alcohol or methyl alcohol as source of carbon food.
Arch Mikrobiol
33
49-51
1959
Saccharomyces cerevisiae
GERO, E; CANDIDO, A
[PURIFICATION OF TURNIP (BRASSICA NAPUS) DEHYDROASCORBIC REDUCTASE AND PRELIMINARY STUDY OF ITS PROPERTIES.]
Bull Soc Chim Biol (Paris)
46
303-16
1964
Brassica rapa subsp. rapa
TAKIGUCHI, H
STUDIES ON DEHYDROASCORBIC ACID REDUCTASE IN ESCHERICHIA COLI K12.
J Vitaminol (Kyoto)
11
114-21
1965
Escherichia coli K-12
BAKHADUR, K
[Effect of modification of carbon-nitrogen ratio on metabolism in cultures of Dhar yeasts.]
Mikrobiologiia
24
141-6
0
yeasts
Grieco, P; Balse-Srinivasan, P; Han, G; Weinberg, D; MacNeil, T; Van der Ploeg, LH; Hruby, VJ
Extensive structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5.
J Pept Res
62
199-206
2003
Homo sapiens
Chan, PC; Shiu, CK; Wong, FW; Wong, JK; Lam, KL; Chan, KM
Common carp metallothionein-1 gene: cDNA cloning, gene structure and expression studies.
Biochim Biophys Acta
1676
162-71
2004
Cyprinus carpio
Cai, M; Cai, C; Mayorov, AV; Xiong, C; Cabello, CM; Soloshonok, VA; Swift, JR; Trivedi, D; Hruby, VJ
Biological and conformational study of beta-substituted prolines in MT-II template: steric effects leading to human MC5 receptor selectivity.
J Pept Res
63
116-31
2004
Homo sapiens
Nury, D; Chabanon, H; Levadoux-Martin, M; Hesketh, J
An eleven nucleotide section of the 3'-untranslated region is required for perinuclear localization of rat metallothionein-1 mRNA.
Biochem J
387
419-28
2005
Rattus
Fu, SL; Hsu, YH; Lee, PY; Hou, WC; Hung, LC; Lin, CH; Chen, CM; Huang, YJ
Dioscorin isolated from Dioscorea alata activates TLR4-signaling pathways and induces cytokine expression in macrophages.
Biochem Biophys Res Commun
339
137-44
2006
Dioscorea alata, Mus musculus, plant
Zhang, YK; Shen, GF; Ru, BG
Survival of Human Metallothionein-2 Transplastomic Chlamydomonas reinhardtii to Ultraviolet B Exposure.
Acta Biochim Biophys Sin (Shanghai)
38
187-93
2006
Chlamydomonas reinhardtii, Homo sapiens
Zhou, XD; Sens, DA; Sens, MA; Namburi, VB; Singh, RK; Garrett, SH; Somji, S
Metallothionein-1 and -2 expression in cadmium- or arsenic-derived human malignant urothelial cells and tumor heterotransplants and as a prognostic indicator in human bladder cancer.
Toxicol Sci
91
467-75
2006
Homo sapiens, Indicator
Ronco, AM; Garrido, F; Llanos, MN
Smoking specifically induces metallothionein-2 isoform in human placenta at term.
Toxicology
223
46-53
2006
Homo sapiens
Toyama, M; Sasaki, M; Hirayama, N; Murooka, Y; Yamashita, M
Construction of an additional metal-binding site in human metallothionein-2.
J Biosci Bioeng
101
354-60
2006
Homo sapiens
Nagai, T; Nagashima, T
Functional properties of dioscorin, a soluble viscous protein from Japanese yam (Dioscorea opposita thunb.) tuber mucilage Tororo.
Z Naturforsch [C]
61
792-8
0
Dioscorea japonica, Tuber
Lee, SS; Yang, SF; Ho, YC; Tsai, CH; Chang, YC
The upregulation of metallothionein-1 expression in areca quid chewing-associated oral squamous cell carcinomas.
Oral Oncol
44
180-6
2008
Areca
Grieco, P; Cai, M; Han, G; Trivedi, D; Campiglia, P; Novellino, E; Hruby, VJ
Further structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5.
Peptides
28
1191-6
2007
Homo sapiens
Nishiuchi, S; Liu, S; Takano, T
Isolation and characterization of a metallothionein-1 protein in Chloris virgata Swartz that enhances stress tolerances to oxidative, salinity and carbonate stress in Saccharomyces cerevisiae.
Biotechnol Lett
29
1301-5
2007
Saccharomyces cerevisiae, Chloris virgata
Liu, YW; Shang, HF; Wang, CK; Hsu, FL; Hou, WC
Immunomodulatory activity of dioscorin, the storage protein of yam (Dioscorea alata cv. Tainong No. 1) tuber.
Food Chem Toxicol
45
2312-8
2007
Tuber, Dioscorea alata, Escherichia coli, Homo sapiens, Mus sp.
Larochelle, O; Labbé, S; Harrisson, JF; Simard, C; Tremblay, V; St-Gelais, G; Govindan, MV; Séguin, C
Nuclear factor-1 and metal transcription factor-1 synergistically activate the mouse metallothionein-1 gene in response to metal ions.
J Biol Chem
283
8190-201
2008
Mus musculus
Gao, D; Wang, GT; Chen, XT; Nie, P
Metallothionein-2 gene from the mandarin fish Siniperca chuatsi: cDNA cloning, tissue expression, and immunohistochemical localization.
Comp Biochem Physiol C Toxicol Pharmacol
149
18-25
2009
Siniperca chuatsi, Metazoa
Liang, SH; Jeng, YP; Chiu, YW; Chen, JH; Shieh, BS; Chen, CY; Chen, CC
Cloning, expression, and characterization of cadmium-induced metallothionein-2 from the earthworms Metaphire posthuma and Polypheretima elongata.
Comp Biochem Physiol C Toxicol Pharmacol
2008
earthworms, Metaphire posthuma, Polypheretima elongata
Liu, YM; Lin, KW
Antioxidative ability, dioscorin stability, and the quality of yam chips from various yam species as affected by processing method.
J Food Sci
74
C118-25
2009
Dioscorea alata
Liu, YW; Liu, JC; Huang, CY; Wang, CK; Shang, HF; Hou, WC
Effects of oral administration of yam tuber storage protein, dioscorin, to BALB/c mice for 21-days on immune responses.
J Agric Food Chem
57
9274-9
2009
Mus sp., Tuber, Dioscorea alata, Mus musculus
Mukhopadhyay, D; Mitra, A; Nandi, P; Varghese, AC; Murmu, N; Chowdhury, R; Chaudhuri, K; Bhattacharyya, AK
Expression of metallothionein-1 (MT-1) mRNA in the rat testes and liver after cadmium injection.
Syst Biol Reprod Med
55
188-92
2009
Rattus
Yu, C; Yang, Y; Liu, X; Zhou, R; Hua, L; Wei, H; Ding, S; Wang, D
[Molecular and biochemical analysis of two genes encoding dehydroascorbate reductase in common wheat]
Sheng Wu Gong Cheng Xue Bao
25
1483-9
2009
Triticum aestivum
Manso, Y; Serra, M; Comes, G; Giralt, M; Carrasco, J; Cols, N; Vasák, M; González-Duarte, P; Hidalgo, J
The comparison of mouse full metallothionein-1 versus alpha and beta domains and metallothionein-1-to-3 mutation following traumatic brain injury reveals different biological motifs.
J Neurosci Res
88
1708-18
2010
Mus musculus
Fu, LS; Ko, YH; Lin, KW; Hsu, JY; Chu, JJ; Chi, CS
Dioscorin protects tight junction protein expression in A549 human airway epithelium cells from dust mite damage.
J Microbiol Immunol Infect
42
457-63
2009
Homo sapiens, Dioscorea alata
Ren, F; Jiang, H; Sun, J; He, L; Li, W; Wang, Y; Wang, Q
Cloning, characterization, expression, and copper sensitivity of the metallothionein-1 gene in the Chinese mitten crab, Eriocheir sinensis.
Mol Biol Rep
38
2383-93
2011
Eriocheir sinensis
Le Martret, B; Poage, M; Shiel, K; Nugent, GD; Dix, PJ
Tobacco chloroplast transformants expressing genes encoding dehydroascorbate reductase, glutathione reductase, and glutathione-S-transferase, exhibit altered anti-oxidant metabolism and improved abiotic stress tolerance.
Plant Biotechnol J
2011
Nicotiana tabacum, plant
Goossens, L
Effects of gamma-ray-induced free radicals on the metal content and amino acid composition of human metallothionein-1.
J Biosci
36
235-41
2011
Homo sapiens
Zhu, F; Yuan, S; Wang, SH; Xi, DH; Li, HH
The higher expression levels of dehydroascorbate reductase and glutathione reductase in salicylic acid-deficient plants may contribute to their alleviated symptom infected with RNA viruses.
Plant Signal Behav
6
2011
Riboviria
Kepp, KP
Full quantum-mechanical structure of the human protein Metallothionein-2.
J Inorg Biochem
107
15-24
2012
Homo sapiens
Xue, YL; Miyakawa, T; Sawano, Y; Tanokura, M
Cloning of genes and enzymatic characterizations of novel dioscorin isoforms from Dioscorea japonica.
Plant Sci
183
14-9
2012
Dioscorea japonica, Escherichia coli, Tuber, Dioscorea alata
Xue, YL; Miyakawa, T; Sawano, Y; Tanokura, M
Crystallization and preliminary X-ray crystallographic analysis of dioscorin from Dioscorea japonica.
Acta Crystallogr Sect F Struct Biol Cryst Commun
68
193-5
2012
Dioscorea japonica, Homo sapiens, Mus musculus, Tuber, Dioscorea alata
Malavolta, M; Basso, A; Piacenza, F; Giacconi, R; Costarelli, L; Pierpaoli, S; Mocchegiani, E
Survival study of metallothionein-1 transgenic mice and respective controls (C57BL/6J): influence of a zinc-enriched environment.
Rejuvenation Res
15
140-3
2012
Mus musculus
Kurita, H; Ohsako, S; Hashimoto, SI; Yoshinaga, J; Tohyama, C
Prenatal zinc deficiency-dependent epigenetic alterations of mouse metallothionein-2 gene.
J Nutr Biochem
2012
Mus musculus
Kwak, S; Park, YC; Seo, JH
Biosynthesis of 3-hydroxypropionic acid from glycerol in recombinant Escherichia coli expressing Lactobacillus brevis dhaB and dhaR gene clusters and E. coli K-12 aldH.
Bioresour Technol
2012
Escherichia coli, Levilactobacillus brevis
Ganasyam, SR; Rao, TB; Murthy, YS; Jyothy, A; Sujatha, M
Association of Estrogen Receptor-? Gene & Metallothionein-1 Gene Polymorphisms in Type 2 Diabetic Women of Andhra Pradesh.
Indian J Clin Biochem
27
69-73
2012
Homo sapiens
Hsu, JY; Chu, JJ; Chou, MC; Chen, YW
Dioscorin Pre-treatment Protects A549 Human Airway Epithelial Cells from Hydrogen Peroxide-Induced Oxidative Stress.
Inflammation
36
1013-9
2013
Homo sapiens
Han, CH; Lin, YS; Lin, SY; Hou, WC
Antioxidant and antiglycation activities of the synthesised dipeptide, Asn-Trp, derived from computer-aided simulation of yam dioscorin hydrolysis and its analogue, Gln-Trp.
Food Chem
147
195-202
2014
Dioscorea alata, Tuber
Han, CH; Lin, YF; Lin, YS; Lee, TL; Huang, WJ; Lin, SY; Hou, WC
Effects of yam tuber protein, dioscorin, on attenuating oxidative status and learning dysfunction in d-galactose-induced BALB/c mice.
Food Chem Toxicol
65
356-63
2014
Mus sp., Tuber, Dioscorea alata
Retraction for Dhar et al., Targeting pseudoknots in H5N1 hemagglutinin using designed aptamers.
Bioinformation
9
1044
2013
H5N1 subtype
Gonzalez-Mejia, ME; Torres-Rasgado, E; Porchia, LM; Salgado, HR; Totolhua, JL; Ortega, A; Hernndez-Kelly, LC; Ruiz-Vivanco, G; Bez-Duarte, BG; Prez-Fuentes, R
Metallothionein-1 and nitric oxide expression are inversely correlated in a murine model of Chagas disease.
Mem Inst Oswaldo Cruz
109
174-81
2014
Mus musculus
Kadota, Y; Aki, Y; Toriuchi, Y; Mizuno, Y; Kawakami, T; Sato, M; Suzuki, S
Deficiency of metallothionein-1 and -2 genes shortens the lifespan of the 129/Sv mouse strain.
Exp Gerontol
66
21-4
2015
Mus musculus
Chidinma, NC; Adewale, A; Chiaka, A
Differential expression of metallothionein-1 and cytochrome p450-2a5 (cyp2a5) in mice in response to lead acetate exposure and industrial effluents in Ibadan, Nigeria.
Toxicol Ind Health
2015
Mus sp.
Malavolta, M; Orlando, F; Piacenza, F; Giacconi, R; Costarelli, L; Basso, A; Lucarini, G; Pierpaoli, E; Provinciali, M
Metallothioneins, longevity and cancer: Comment on "Deficiency of metallothionein-1 and -2 genes shortens the lifespan of the 129/Sv mouse strain".
Exp Gerontol
73
28-30
2016
Mus musculus
Gong, L; Li, W; Li, J; Li, WE; Wu, WR; Yu, LW
Cloning, characterization, and expression of cadmium-induced metallothionein-2 gene from earthworm Pheretima aspergillum (E. Perrier).
Genet Mol Res
14
16782-92
2015
Amynthas aspergillus, Metaphire sieboldi, Pleurothallis aspergillum
Manso, Y; Comes, G; Lpez-Ramos, JC; Belfiore, M; Molinero, A; Giralt, M; Carrasco, J; Adlard, PA; Bush, AI; Delgado-Garca, JM; Hidalgo, J
Overexpression of Metallothionein-1 Modulates the Phenotype of the Tg2576 Mouse Model of Alzheimer's Disease.
J Alzheimers Dis
51
81-95
2016
Mus musculus, Homo sapiens, Mus sp.
Comes, G; Manso, Y; Escrig, A; Fernandez-Gayol, O; Sanchis, P; Molinero, A; Giralt, M; Carrasco, J; Hidalgo, J
Influence of Transgenic Metallothionein-1 on Gliosis, CA1 Neuronal Loss, and Brain Metal Levels of the Tg2576 Mouse Model of Alzheimer's Disease.
Int J Mol Sci
18
2017
Mus musculus
Sharma, S; Gupta, R; Deswal, R
Dioscorea alata tuber proteome analysis shows over thirty dioscorin isoforms and novel tuber proteins.
Plant Physiol Biochem
114
128-137
2017
Tuber, Dioscorea alata, Dioscorea
Shih, SL; Lin, YS; Lin, SY; Hou, WC
Effects of yam dioscorin interventions on improvements of the metabolic syndrome in high-fat diet-induced obese rats.
Bot Stud
56
4
2015
Rattus, Dioscorea alata
Kim, YS; Kim, IS; Boyd, JS; Taton, A; Golden, JW; Yoon, HS
Enhanced biomass and oxidative stress tolerance of Synechococcus elongatus PCC 7942 overexpressing the DHAR gene from Brassica juncea.
Biotechnol Lett
2017
Synechococcus elongatus PCC 7942 = FACHB-805, Brassica juncea
Liu, L; Huang, Y; Huang, X; Yang, J; Wu, W; Xu, Y; Cong, Z; Xie, J; Xia, W; Huang, D
Characterization of the Dioscorin Gene Family in Dioscorea alata Reveals a Role in Tuber Development and Environmental Response.
Int J Mol Sci
18
2017
Tuber, Dioscorea alata, plant
Bodra, N; Young, D; Rosado, LA; Pallo, A; Wahni, K; De Proft, F; Huang, J; Van Breusegem, F; Messens, J
Erratum: Arabidopsis thaliana dehydroascorbate reductase 2: Conformational flexibility during catalysis.
Sci Rep
7
46896
2017
Arabidopsis thaliana
Wu, GC; Lin, SY; Liang, HJ; Hou, WC
135-Day Interventions of Yam Dioscorin and the Dipeptide Asn-Trp (NW) To Reduce Weight Gains and Improve Impaired Glucose Tolerances in High-Fat Diet-Induced C57BL/6 Mice.
J Agric Food Chem
66
645-652
2018
Mus sp., Dioscorea alata
Comes, G; Fernandez-Gayol, O; Molinero, A; Giralt, M; Capdevila, M; Atrian, S; Hidalgo, J
Mouse metallothionein-1 and metallothionein-2 are not biologically interchangeable in an animal model of multiple sclerosis, EAE.
Metallomics
11
327-337
2019
Mus musculus, animal
McNeill, RV; Mason, AS; Hodson, ME; Catto, JWF; Southgate, J
Specificity of the Metallothionein-1 Response by Cadmium-Exposed Normal Human Urothelial Cells.
Int J Mol Sci
20
2019
Homo sapiens
Kimura, T; Hosaka, T; Nakanishi, T; Aozasa, O
Long-term cadmium exposure enhances metallothionein-1 induction after subsequent exposure to high concentrations of cadmium in P1798 mouse lymphosarcoma cells.
J Toxicol Sci
44
309-316
2019
Mus musculus
Liu, J; Tan, S; Wang, Y; Luo, J; Long, Y; Mei, X; Tang, Y
Role of Metallothionein-1 and Metallothionein-2 in the Neuroprotective Mechanism of Sevoflurane Preconditioning in Mice.
J Mol Neurosci
2020
Mus sp.
Kim, YS; Park, SI; Kim, JJ; Boyd, JS; Beld, J; Taton, A; Lee, KI; Kim, IS; Golden, JW; Yoon, HS
Expression of Heterologous OsDHAR Gene Improves Glutathione (GSH)-Dependent Antioxidant System and Maintenance of Cellular Redox Status in Synechococcus elongatus PCC 7942.
Front Plant Sci
11
231
2020
cyanobacterium, Lonicera japonica, Oryza sativa, Synechococcus elongatus, Synechococcus elongatus PCC 7942 = FACHB-805
Bulley, SM; Cooney, JM; Laing, W
Elevating Ascorbate in Arabidopsis Stimulates the Production of Abscisic Acid, Phaseic Acid, and to a Lesser Extent Auxin (IAA) and Jasmonates, Resulting in Increased Expression of DHAR1 and Multiple Transcription Factors Associated with Abiotic Stress Tolerance.
Int J Mol Sci
22
2021
Arabidopsis
Kim YS;Kim IS;Shin SY;Park TH;Park HM;Kim YH;Lee GS;Kang HG;Lee SH;Yoon HS
Overexpression of Dehydroascorbate Reductase Confers Enhanced Tolerance to Salt Stress in Rice Plants (Oryza sativa L. japonica)
Zeitschrift fur Acker- und Pflanzenbau.
200
444-456
2014
Oryza sativa, Zea mays, plant
Xue YL;Miyakawa T;Sawano Y;Tanokura M
Cloning of genes and enzymatic characterizations of novel dioscorin isoforms from Dioscorea japonica
Plant science : an international journal of experimental plant biology
183
14-19
2012
Dioscorea japonica, Escherichia coli, Tuber, Dioscorea alata
Eltayeb AminElsadig;Kawano Naoyoshi;Badawi GhaziHamid;Kaminaka Hironori;Sanekata Takeshi;Morishima Isao;Shibahara Toshiyuki;Inanaga Shinobu;Tanaka Kiyoshi
Enhanced tolerance to ozone and drought stresses in transgenic tobacco overexpressing dehydroascorbate reductase in cytosol.
Physiologia plantarum
127
57-65
2006
Nicotiana tabacum, Arabidopsis thaliana
Chen YT;Lin KW
Effects of heating temperature on the total phenolic compound, antioxidative ability and the stability of dioscorin of various yam cultivars
Food chemistry
101
955-963
2007
Dioscorea alata
Nishiuchi S;Liu S;Takano T
Isolation and characterization of a metallothionein-1 protein in Chloris virgata Swartz that enhances stress tolerances to oxidative, salinity and carbonate stress in Saccharomyces cerevisiae
Biotechnology letters
29
1301-1305
2007
Saccharomyces cerevisiae, Chloris virgata
Moutiez, M; Quéméneur, E; Sergheraert, C; Lucas, V; Tartar, A; Davioud-Charvet, E
Glutathione-dependent activities of Trypanosoma cruzi p52 makes it a new member of the thiol:disulphide oxidoreductase family.
Biochem J
322 ( Pt 1)
43-8
1997
Trypanosoma cruzi
Del Carmen Córdoba-Pedregosa, M; Córdoba, F; Villalba, JM; González-Reyes, JA
Zonal changes in ascorbate and hydrogen peroxide contents, peroxidase, and ascorbate-related enzyme activities in onion roots.
Plant Physiol
131
697-706
2003
Allium cepa, Electron
Colville, L; Smirnoff, N
Antioxidant status, peroxidase activity, and PR protein transcript levels in ascorbate-deficient Arabidopsis thaliana vtc mutants.
J Exp Bot
59
3857-68
2008
Arabidopsis thaliana
Djanaguiraman, M; Sheeba, JA; Devi, DD; Bangarusamy, U; Prasad, PV
Nitrophenolates spray can alter boll abscission rate in cotton through enhanced peroxidase activity and increased ascorbate and phenolics levels.
J Plant Physiol
2009
Gossypium hirsutum, plant
Ali, MB; Hahn, EJ; Paek, KY
Effects of temperature on oxidative stress defense systems, lipid peroxidation and lipoxygenase activity in Phalaenopsis.
Plant Physiol Biochem
43
213-23
2005
Embryophyta, Phalaenopsis, plant
Padilla, CA; Martínez-Galisteo, E; Bárcena, JA; Spyrou, G; Holmgren, A
Purification from placenta, amino acid sequence, structure comparisons and cDNA cloning of human glutaredoxin.
Eur J Biochem
227
27-34
1995
Mus musculus
Padilla, CA; Spyrou, G; Holmgren, A
High-level expression of fully active human glutaredoxin (thioltransferase) in E. coli and characterization of Cys7 to Ser mutant protein.
FEBS Lett
378
69-73
1996
Homo sapiens
Park, JB; Levine, M
Purification, cloning and expression of dehydroascorbic acid-reducing activity from human neutrophils: identification as glutaredoxin.
Biochem J
315 ( Pt 3)
931-8
1996
Homo sapiens
Gvakharia, BO; Koonin, EK; Mathews, CK
Vaccinia virus G4L gene encodes a second glutaredoxin.
Virology
226
408-11
1996
Vaccinia virus, Molluscum contagiosum virus
Sha, S; Minakuchi, K; Higaki, N; Sato, K; Ohtsuki, K; Kurata, A; Yoshikawa, H; Kotaru, M; Masumura, T; Ichihara, K; Tanaka, K
Purification and characterization of glutaredoxin (thioltransferase) from rice (Oryza sativa L.).
J Biochem (Tokyo)
121
842-8
1997
Oryza sativa, Escherichia coli
White, CL; Weisberg, AS; Moss, B
A glutaredoxin, encoded by the G4L gene of vaccinia virus, is essential for virion morphogenesis.
J Virol
74
9175-83
2000
Vaccinia virus
Dubey, AK; Kumar, N; Sahu, N; Verma, PK; Chakrabarty, D; Behera, SK; Mallick, S
Response of two rice cultivars differing in their sensitivity towards arsenic, differs in their expression of glutaredoxin and glutathione S transferase genes and antioxidant usage.
Ecotoxicol Environ Saf
124
393-405
2016
Electron
Kumar, A; Dubey, AK; Kumar, V; Ansari, MA; Narayan, S; Meenakshi, ; Kumar, S; Pandey, V; Shirke, PA; Pande, V; Sanyal, I
Overexpression of rice glutaredoxin genes LOC_Os02g40500 and LOC_Os01g27140 regulate plant responses to drought stress.
Ecotoxicol Environ Saf
200
110721
2020
Felis catus
Kumar, A; Kumar, V; Dubey, AK; Ansari, MA; Narayan, S; Meenakshi, ; Kumar, S; Pandey, V; Pande, V; Sanyal, I
Chickpea glutaredoxin (CaGrx) gene mitigates drought and salinity stress by modulating the physiological performance and antioxidant defense mechanisms.
Physiol Mol Biol Plants
27
923-944
2021
Felis catus
Arisi, AC; Cornic, G; Jouanin, L; Foyer, CH
Overexpression of iron superoxide dismutase in transformed poplar modifies the regulation of photosynthesis at low CO2 partial pressures or following exposure to the prooxidant herbicide methyl viologen.
Plant Physiol
117
565-74
1998
Populus, Arabidopsis thaliana
Ghoshal, K; Majumder, S; Li, Z; Bray, TM; Jacob, ST
Transcriptional induction of metallothionein-I and -II genes in the livers of Cu,Zn-superoxide dismutase knockout mice.
Biochem Biophys Res Commun
264
735-42
1999
Mus sp., Lethrinidae, Metazoa
Shi, Q; Bao, Z; Zhu, Z; He, Y; Qian, Q; Yu, J
Silicon-mediated alleviation of Mn toxicity in Cucumis sativus in relation to activities of superoxide dismutase and ascorbate peroxidase.
Phytochemistry
66
1551-9
2005
Cucumis sativus, plant
Khanna-Chopra, R; Semwal, VK
Superoxide dismutase and ascorbate peroxidase are constitutively more thermotolerant than other antioxidant enzymes in Chenopodium album.
Physiol Mol Biol Plants
17
339-46
2011
Chenopodium album, Felis catus
Alam, J; Cai, J; Smith, A
Isolation and characterization of the mouse heme oxygenase-1 gene. Distal 5' sequences are required for induction by heme or heavy metals.
J Biol Chem
269
1001-9
1994
Mus musculus
Moreira, V; de Castro Souto, PC; Ramirez Vinolo, MA; Lomonte, B; Mara Gutirrez, J; Curi, R; Teixeira, C
A catalytically-inactive snake venom Lys49 phospholipase A(2) homolog induces expression of cyclooxygenase-2 and production of prostaglandins through selected signaling pathways in macrophages.
Eur J Pharmacol
2013
Mus musculus, snake
Miyake, C; Shinzaki, Y; Nishioka, M; Horiguchi, S; Tomizawa, K
Photoinactivation of ascorbate peroxidase in isolated tobacco chloroplasts: Galdieria partita APX maintains the electron flux through the water-water cycle in transplastomic tobacco plants.
Plant Cell Physiol
47
200-10
2006
Nicotiana tabacum, Galdieria partita, Electron
Brouwer, M; Syring, R; Hoexum Brouwer, T
Role of a copper-specific metallothionein of the blue crab, Callinectes sapidus, in copper metabolism associated with degradation and synthesis of hemocyanin.
J Inorg Biochem
88
228-39
2002
Callinectes sapidus
Rafferty, JA; Fan, CY; Potter, PM; Watson, AJ; Cawkwell, L; O'Connor, PJ; Margison, GP
Tissue-specific expression and induction of human O6-alkylguanine-DNA alkyltransferase in transgenic mice.
Mol Carcinog
6
26-31
1992
Mus musculus
Burfeind, P; Chernicky, CL; Rininsland, F; Ilan, J; Ilan, J
Antisense RNA to the type I insulin-like growth factor receptor suppresses tumor growth and prevents invasion by rat prostate cancer cells in vivo.
Proc Natl Acad Sci U S A
93
7263-8
1996
Rattus
Tanaka, T; Masuzaki, H; Yasue, S; Ebihara, K; Shiuchi, T; Ishii, T; Arai, N; Hirata, M; Yamamoto, H; Hayashi, T; Hosoda, K; Minokoshi, Y; Nakao, K
Central melanocortin signaling restores skeletal muscle AMP-activated protein kinase phosphorylation in mice fed a high-fat diet.
Cell Metab
5
395-402
2007
Mus sp., Mus musculus
Yin, ZL; Dahlstrom, JE; Le Couteur, DG; Board, PG
Immunohistochemistry of omega class glutathione S-transferase in human tissues.
J Histochem Cytochem
49
983-7
2001
Homo sapiens
Dixon, DP; Davis, BG; Edwards, R
Functional divergence in the glutathione transferase superfamily in plants. Identification of two classes with putative functions in redox homeostasis in Arabidopsis thaliana.
J Biol Chem
277
30859-69
2002
Arabidopsis, Arabidopsis thaliana, Homo sapiens, plant
Sampayo-Reyes, A; Zakharyan, RA
Tocopherol esters inhibit human glutathione S-transferase omega.
Acta Biochim Pol
53
547-52
2006
Homo sapiens, Theta
Harju, TH; Peltoniemi, MJ; Rytilä, PH; Soini, Y; Salmenkivi, KM; Board, PG; Ruddock, LW; Kinnula, VL
Glutathione S-transferase omega in the lung and sputum supernatants of COPD patients.
Respir Res
8
48
2007
Homo sapiens
Escobar-Garca, DM; Del Razo, LM; Sanchez-Pea, LC; Mandeville, PB; Lopez-Campos, C; Escudero-Lourdes, C
Association of glutathione S-transferase ? 1-1 polymorphisms (A140D and E208K) with the expression of interleukin-8 (IL-8), transforming growth factor beta (TGF-?), and apoptotic protease-activating factor 1 (Apaf-1) in humans chronically exposed to arsenic in drinking water.
Arch Toxicol
2012
Homo sapiens
Rezaei, MK; Shobbar, ZS; Shahbazi, M; Abedini, R; Zare, S
Glutathione S-transferase (GST) family in barley: Identification of members, enzyme activity, and gene expression pattern.
J Plant Physiol
170
1277-84
2013
Theta
Csiszr, J; Horvth, E; Vry, Z; Gall, A; Bela, K; Brunner, S; Tari, I
Glutathione transferase supergene family in tomato: Salt stress-regulated expression of representative genes from distinct GST classes in plants primed with salicylic acid.
Plant Physiol Biochem
78
15-26
2014
Theta
Ismaiel, AA; Papenbrock, J
Effect of Patulin from Penicillium vulpinum on the Activity of Glutathione-S-Transferase and Selected Antioxidative Enzymes in Maize.
Int J Environ Res Public Health
14
2017
Zea mays
Vaish, S; Awasthi, P; Tiwari, S; Tiwari, SK; Gupta, D; Basantani, MK
In silico genome-wide identification and characterization of glutathione S-transferase gene family in Vigna radiata (L.) Wilczek.
Genome
2018
Theta
Tortora, G; Budillon, A; Yokozaki, H; Clair, T; Pepe, S; Merlo, G; Rohlff, C; Cho-Chung, YS
Retroviral vector-mediated overexpression of the RII beta subunit of the cAMP-dependent protein kinase induces differentiation in human leukemia cells and reverts the transformed phenotype of mouse fibroblasts.
Cell Growth Differ
5
753-9
1994
Homo sapiens, Mus musculus
Karthik, S; Tuteja, N; Ganapathi, A; Manickavasagam, M
Pea p68, a DEAD-box helicase, enhances salt tolerance in marker-free transgenic plants of soybean [Glycine max (L.) Merrill].
3 Biotech
9
10
2019
Glycine max, Felis catus
Qi, ZY; Ahammed, GJ; Jiang, CY; Li, CX; Zhou, J
The E3 ubiquitin ligase gene SlRING1 is essential for plant tolerance to cadmium stress in Solanum lycopersicum.
J Biotechnol
324
239-247
2020
Felis catus
Hasanuzzaman, M; Fujita, M
Exogenous sodium nitroprusside alleviates arsenic-induced oxidative stress in wheat (Triticum aestivum L.) seedlings by enhancing antioxidant defense and glyoxalase system.
Ecotoxicology
22
584-96
2013
Felis catus
Hossain, MA; Hasanuzzaman, M; Fujita, M
Up-regulation of antioxidant and glyoxalase systems by exogenous glycinebetaine and proline in mung bean confer tolerance to cadmium stress.
Physiol Mol Biol Plants
16
259-72
2010
Felis catus
Mostofa, MG; Hossain, MA; Fujita, M
Trehalose pretreatment induces salt tolerance in rice (Oryza sativa L.) seedlings: oxidative damage and co-induction of antioxidant defense and glyoxalase systems.
Protoplasma
252
461-75
2015
Felis catus
Hasanuzzaman, M; Nahar, K; Gill, SS; Alharby, HF; Razafindrabe, BH; Fujita, M
Hydrogen Peroxide Pretreatment Mitigates Cadmium-Induced Oxidative Stress in Brassica napus L.: An Intrinsic Study on Antioxidant Defense and Glyoxalase Systems.
Front Plant Sci
8
115
2017
Felis catus
Hasanuzzaman, M; Nahar, K; Anee, TI; Fujita, M
Exogenous Silicon Attenuates Cadmium-Induced Oxidative Stress in Brassica napus L. by Modulating AsA-GSH Pathway and Glyoxalase System.
Front Plant Sci
8
1061
2017
Felis catus
Liu, P; Li, Q; Gao, Y; Wang, H; Chai, L; Yu, H; Jiang, W
A New Perspective on the Effect of UV-B on l-Ascorbic Acid Metabolism in Cucumber Seedlings.
J Agric Food Chem
67
4444-4452
2019
Cucumis sativus
Xu, YY; Xu, YS; Wang, Y; Wu, Q; Lu, YF; Liu, J; Shi, JS
Dendrobium nobile Lindl. alkaloids regulate metabolism gene expression in livers of mice.
J Pharm Pharmacol
69
1409-1417
2017
Mus sp.
Arango, J; Salazar, B; Welsch, R; Sarmiento, F; Beyer, P; Al-Babili, S
Putative storage root specific promoters from cassava and yam: cloning and evaluation in transgenic carrots as a model system.
Plant Cell Rep
2010
Manihot esculenta, Dioscorea alata
Zhou, PB; Thiele, DJ
Isolation of a metal-activated transcription factor gene from Candida glabrata by complementation in Saccharomyces cerevisiae.
Proc Natl Acad Sci U S A
88
6112-6
1991
Escherichia coli
Pukacka, S; Ratajczak, E
Antioxidative response of ascorbate-glutathione pathway enzymes and metabolites to desiccation of recalcitrant Acer saccharinum seeds.
J Plant Physiol
163
1259-66
2006
Acer saccharinum
Ahanger, MA; Qin, C; Maodong, Q; Dong, XX; Ahmad, P; Abd Allah, EF; Zhang, L
Spermine application alleviates salinity induced growth and photosynthetic inhibition in Solanum lycopersicum by modulating osmolyte and secondary metabolite accumulation and differentially regulating antioxidant metabolism.
Plant Physiol Biochem
144
1-13
2019
Felis catus
Eisele, I; Wood, IS; German, AJ; Hunter, L; Trayhurn, P
Adipokine gene expression in dog adipose tissues and dog white adipocytes differentiated in primary culture.
Horm Metab Res
37
474-81
2005
Canis lupus familiaris
Yamazaki, S; Nakanishi, M; Hamamoto, T; Hirata, H; Ebihara, A; Tokue, A; Kagawa, Y
Expression of human metallothionein-II fusion protein in Escherichia coli.
Biochem Int
28
451-60
1992
Escherichia coli, Homo sapiens
Nagamine, T; Suzuki, K; Kondo, T; Nakazato, K; Kakizaki, S; Takagi, H; Nakajima, K
Interferon-alpha-induced changes in metallothionein expression in liver biopsies from patients with chronic hepatitis C.
Can J Gastroenterol
19
481-6
2005
Homo sapiens, Hepacivirus C
Naar, EM; Bartke, A; Majumdar, SS; Buonomo, FC; Yun, JS; Wagner, TE
Fertility of transgenic female mice expressing bovine growth hormone or human growth hormone variant genes.
Biol Reprod
45
178-87
1991
Mus sp., Mus musculus
Keeney, DS; Murry, BA; Bartke, A; Wagner, TE; Mason, JI
Growth hormone transgenes regulate the expression of sex-specific isoforms of 3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase in mouse liver and gonads.
Endocrinology
133
1131-8
1993
Bos taurus, Homo sapiens, Mus musculus, Mus sp.
ElSayed, AI; Rafudeen, MS; El-Hamahmy, MAM; Odero, DC; Hossain, MS
Enhancing antioxidant systems by exogenous spermine and spermidine in wheat (Triticum aestivum) seedlings exposed to salt stress.
Funct Plant Biol
45
745-759
2018
Triticum aestivum
Rempelos L;Cooper J;Wilcockson S;Eyre M;Shotton P;Volakakis N;Orr CH;Leifert C;Gatehouse AMR;Ttard-Jones C
Quantitative proteomics to study the response of potato to contrasting fertilisation regimes
Molecular breeding : new strategies in plant improvement
31
363-378
2013
Tuber
Huang, M; Xu, Q; Deng, XX
L-Ascorbic acid metabolism during fruit development in an ascorbate-rich fruit crop chestnut rose (Rosa roxburghii Tratt).
J Plant Physiol
171
1205-16
2014
Rosa roxburghii, Arabidopsis
Liao, VH; Freedman, JH
Cadmium-regulated genes from the nematode Caenorhabditis elegans. Identification and cloning of new cadmium-responsive genes by differential display.
J Biol Chem
273
31962-70
1998
Caenorhabditis elegans
Dawson, PA; Gardiner, B; Grimmond, S; Markovich, D
Transcriptional profile reveals altered hepatic lipid and cholesterol metabolism in hyposulfatemic NaS1 null mice.
Physiol Genomics
26
116-24
2006
Mus sp.
Singh, R; Kesavan, AK; Landi, M; Kaur, S; Thakur, S; Zheng, B; Bhardwaj, R; Sharma, A
5-aminolevulinic acid regulates Krebs cycle, antioxidative system and gene expression in Brassica juncea L. to confer tolerance against lead toxicity.
J Biotechnol
323
283-292
2020
Felis catus
Chin, DC; Hsieh, CC; Lin, HY; Yeh, KW
A Low Glutathione Redox State Couples with a Decreased Ascorbate Redox Ratio to Accelerate Flowering in Oncidium Orchid.
Plant Cell Physiol
57
423-36
2016
Oncidium
Li, X; Li, C; Cheng, Y; Hou, J; Zhang, J; Ge, Y
Postharvest Application of Acibenzolar-S-methyl Delays the Senescence of Pear Fruit by Regulating Reactive Oxygen Species and Fatty Acid Metabolism.
J Agric Food Chem
68
4991-4999
2020
Pyrus
Aravind, P; Prasad, MN
Modulation of cadmium-induced oxidative stress in Ceratophyllum demersum by zinc involves ascorbate-glutathione cycle and glutathione metabolism.
Plant Physiol Biochem
43
107-16
2005
Ceratophyllum demersum, plant
Suemori, S; Shimazawa, M; Kawase, K; Satoh, M; Nagase, H; Yamamoto, T; Hara, H
Metallothionein, an endogenous antioxidant, protects against retinal neuron damage in mice.
Invest Ophthalmol Vis Sci
47
3975-82
2006
Mus sp.
Li, G; Peng, X; Wei, L; Kang, G
Salicylic acid increases the contents of glutathione and ascorbate and temporally regulates the related gene expression in salt-stressed wheat seedlings.
Gene
529
321-5
2013
Triticum aestivum, Embryophyta
Shewry, PR
Tuber storage proteins.
Ann Bot (Lond)
91
755-69
2003
Solanum tuberosum, Ipomoea batatas, Dioscorea alata
Gaidamashvili, M; Ohizumi, Y; Iijima, S; Takayama, T; Ogawa, T; Muramoto, K
Characterization of the yam tuber storage proteins from Dioscorea batatas exhibiting unique lectin activities.
J Biol Chem
279
26028-35
2004
Dioscorea alata, Arabidopsis thaliana
Sharma, S; Sehrawat, A; Deswal, R
Asada-Halliwell pathway maintains redox status in Dioscorea alata tuber which helps in germination.
Plant Sci
250
20-9
2016
Tuber
Raynaud, C; Sarçabal, P; Meynial-Salles, I; Croux, C; Soucaille, P
Molecular characterization of the 1,3-propanediol (1,3-PD) operon of Clostridium butyricum.
Proc Natl Acad Sci U S A
100
5010-5
2003
Clostridium butyricum
Li, W; Trovero, F; Cordier, J; Wang, Y; Drieu, K; Papadopoulos, V
Prenatal exposure of rats to Ginkgo biloba extract (EGb 761) increases neuronal survival/growth and alters gene expression in the developing fetal hippocampus.
Brain Res Dev Brain Res
144
169-80
2003
Ginkgo biloba, Rattus, Hippocampus
Hasanuzzaman, M; Nahar, K; Alam, MM; Fujita, M
Modulation of antioxidant machinery and the methylglyoxal detoxification system in selenium-supplemented Brassica napus seedlings confers tolerance to high temperature stress.
Biol Trace Elem Res
161
297-307
2014
Felis catus
Nahar, K; Hasanuzzaman, M; Alam, MM; Fujita, M
Glutathione-induced drought stress tolerance in mung bean: coordinated roles of the antioxidant defence and methylglyoxal detoxification systems.
AoB Plants
7
2015
Vigna radiata var. radiata
Rohman, MM; Islam, MR; Monsur, MB; Amiruzzaman, M; Fujita, M; Hasanuzzaman, M
Trehalose Protects Maize Plants from Salt Stress and Phosphorus Deficiency.
Plants (Basel)
8
2019
Felis catus, Zea mays
Gangwar, S; Singh, VP; Garg, SK; Prasad, SM; Maurya, JN
Kinetin Supplementation Modifies Chromium (VI) Induced Alterations in Growth and Ammonium Assimilation in Pea Seedlings.
Biol Trace Elem Res
2011
Pisum sativum, Felis catus
Beattie, JH; Wood, AM; Newman, AM; Bremner, I; Choo, KH; Michalska, AE; Duncan, JS; Trayhurn, P
Obesity and hyperleptinemia in metallothionein (-I and -II) null mice.
Proc Natl Acad Sci U S A
95
358-63
1998
Mus sp., animal
Palmiter, RD; Sandgren, EP; Koeller, DM; Brinster, RL
Distal regulatory elements from the mouse metallothionein locus stimulate gene expression in transgenic mice.
Mol Cell Biol
13
5266-75
1993
Mus musculus
Contreras, L; Mella, D; Moenne, A; Correa, JA
Differential responses to copper-induced oxidative stress in the marine macroalgae Lessonia nigrescens and Scytosiphon lomentaria (Phaeophyceae).
Aquat Toxicol
94
94-102
2009
Felis catus, Labeo nigrescens, Lessonia nigrescens, plant, Scytosiphon lomentaria
Mart, MC; Florez-Sarasa, I; Camejo, D; Pallol, B; Ortiz, A; Ribas-Carb, M; Jimnez, A; Sevilla, F
Response of mitochondrial antioxidant system and respiratory pathways to reactive nitrogen species in pea leaves.
Physiol Plant
2012
plant
Sordet, C; Contreras-Porcia, L; Lovazzano, C; Goulitquer, S; Andrade, S; Potin, P; Correa, JA
Physiological plasticity of Dictyota kunthii (Phaeophyceae) to copper excess.
Aquat Toxicol
150C
220-228
2014
Felis catus, Davilla kunthii
Gonzlez, A; Vidal, C; Espinoza, D; Moenne, A
Anthracene induces oxidative stress and activation of antioxidant and detoxification enzymes in Ulva lactuca (Chlorophyta).
Sci Rep
11
7748
2021
Felis catus
Bode, AM; Green, E; Yavarow, CR; Wheeldon, SL; Bolken, S; Gomez, Y; Rose, RC
Ascorbic acid regeneration by bovine iris-ciliary body.
Curr Eye Res
12
593-601
1993
Bos taurus
Sun, H; Cao, F; Wang, N; Zhang, M; Mosaddek Ahmed, I; Zhang, G; Wu, F
Differences in grain ultrastructure, phytochemical and proteomic profiles between the two contrasting grain Cd-accumulation barley genotypes.
PLoS One
8
e79158
2013
Hordeum vulgare
Huang, SS; Deng, JS; Chen, HJ; Lin, YH; Huang, GJ
Antioxidant activities of two metallothionein-like proteins from sweet potato (Ipomoea batatas [L.] Lam. `Tainong 57') storage roots and their synthesized peptides.
Bot Stud
55
64
2014
Escherichia coli
Díaz, C; León, G; Rucavado, A; Rojas, N; Schroit, AJ; Gutiérrez, JM
Modulation of the susceptibility of human erythrocytes to snake venom myotoxic phospholipases A(2): role of negatively charged phospholipids as potential membrane binding sites.
Arch Biochem Biophys
391
56-64
2001
Bothrops asper
Yu, JW; Choi, JS; Upadhyaya, CP; Kwon, SO; Gururani, MA; Nookaraju, A; Nam, JH; Choi, CW; Kim, SI; Ajappala, H; Kim, HS; Jeon, JH; Park, SW
Dynamic proteomic profile of potato tuber during its in vitro development.
Plant Sci
195
1-9
2012
Tuber
Bezdi, MS; Toorchi, M; Pourabad, RF; Zarghami, N; Nouri, MZ; Komatsu, S
PROTEOME ANALYSIS OF GUT AND SALIVARY GLAND PROTEINS OF FIFTH-INSTAR NYMPH AND ADULTS OF THE SUNN PEST, Eurygaster integriceps.
Arch Insect Biochem Physiol
81
105-19
2012
plant
Yu JW;Choi JS;Upadhyaya CP;Kwon SO;Gururani MA;Nookaraju A;Nam JH;Choi CW;Kim SI;Ajappala H;Kim Hs;Jeon JH;Park SW
Dynamic proteomic profile of potato tuber during its in vitro development
Plant science : an international journal of experimental plant biology
195
1-9
2012
Tuber
Lebel, M; Bertrand, R; Mes-Masson, AM
Decreased Fas antigen receptor expression in testicular tumor cell lines derived from polyomavirus large T-antigen transgenic mice.
Oncogene
12
1127-35
1996
Mus musculus, Polyomavirus sp.
Nahar, K; Hasanuzzaman, M; Suzuki, T; Fujita, M
Polyamines-induced aluminum tolerance in mung bean: A study on antioxidant defense and methylglyoxal detoxification systems.
Ecotoxicology
26
58-73
2017
Vigna radiata var. radiata, plant
MacArthur, CA; Lieberman, MW
Different types of hypersensitive sites in the mouse metallothionein gene region.
J Biol Chem
262
2161-5
1987
Mus musculus
Wang J;Zhu YK;Wang HY;Zhang H;Wang KY
Inhibitory effects of esterified whey protein fractions by inducing chemical defense against tobacco mosaic virus (TMV) in tobacco seedlings
Industrial crops and products.
37
207-212
2012
tobacco mosaic virus
Ginder, GD; Whitters, M; Kelley, K; Chase, RA
In vivo demethylation of chicken embryonic beta-type globin genes with 5-azacytidine.
Prog Clin Biol Res
134
501-10
1983
Gallus gallus, Papio anubis, Homo sapiens, Mus musculus
Ikenaka, Y; Nakayama, SM; Muroya, T; Yabe, J; Konnai, S; Darwish, WS; Muzandu, K; Choongo, K; Mainda, G; Teraoka, H; Umemura, T; Ishizuka, M
Effects of environmental lead contamination on cattle in a lead/zinc mining area: Changes in cattle immune systems on exposure to lead in vivo and in vitro.
Environ Toxicol Chem
31
2300-5
2012
Bos taurus
Kiddle, G; Pastori, GM; Bernard, S; Pignocchi, C; Antoniw, J; Verrier, PJ; Foyer, CH
Effects of leaf ascorbate content on defense and photosynthesis gene expression in Arabidopsis thaliana.
Antioxid Redox Signal
5
23-32
2003
Arabidopsis thaliana, Electron, plant
Zhang, Y; Chen, CX; Feng, HP; Wang, XJ; Roessner, U; Walker, R; Cheng, ZY; An, YQ; Du, B; Bai, JG
Transcriptome Profiling Combined With Activities of Antioxidant and Soil Enzymes Reveals an Ability of Pseudomonas sp. CFA to Mitigate p-Hydroxybenzoic and Ferulic Acid Stresses in Cucumber.
Front Microbiol
11
522986
2020
Cucumis sativus
Davis, SR; McMahon, RJ; Cousins, RJ
Metallothionein knockout and transgenic mice exhibit altered intestinal processing of zinc with uniform zinc-dependent zinc transporter-1 expression.
J Nutr
128
825-31
1998
Mus musculus, Mus sp.
Lee, J; Park, J; Jang, B; Knudsen, TB
Altered expression of genes related to zinc homeostasis in early mouse embryos exposed to di-2-ethylhexyl phthalate.
Toxicol Lett
152
1-10
2004
Mus musculus
Gulick, J; Robbins, J
Cell-type-specific transgenesis in the mouse.
Methods Mol Biol
561
91-104
2009
Mus musculus
Guarino, MP; Altomare, A; Barera, S; Locato, V; Cocca, S; Franchin, C; Arrigoni, G; Vannini, C; Grossi, S; Campomenosi, P; Pasqualetti, V; Bracale, M; Alloni, R; De Gara, L; Cicala, M
Effect of Inulin on Proteome Changes Induced by Pathogenic Lipopolysaccharide in Human Colon.
PLoS One
12
e0169481
2017
Homo sapiens
Loney, KD; Uddin, KR; Singh, SM
Strain-specific brain metallothionein II (MT-II) gene expression, its ethanol responsiveness, and association with ethanol preference in mice.
Alcohol Clin Exp Res
27
388-95
2003
Mus sp.
Cai, L; Cherian, MG; Iskander, S; Leblanc, M; Hammond, RR
Metallothionein induction in human CNS in vitro: neuroprotection from ionizing radiation.
Int J Radiat Biol
76
1009-17
2000
Homo sapiens
Geebelen, W; Vangronsveld, J; Adriano, DC; Van Poucke, LC; Clijsters, H
Effects of Pb-EDTA and EDTA on oxidative stress reactions and mineral uptake in Phaseolus vulgaris.
Physiol Plant
115
377-384
2002
Phaseolus vulgaris, plant
Okuda, T; Matsuda, Y; Sugawara, M; Sagisaka, S
Metabolic response to treatment with cold, paraquat, or 3-amino-1,2,4-triazole in leaves of winter wheat.
Biosci Biotechnol Biochem
56
1911-5
1992
Triticum aestivum
Braha, B; Tintemann, H; Krauss, G; Ehrman, J; Bärlocher, F; Krauss, GJ
Stress response in two strains of the aquatic hyphomycete Heliscus lugdunensis after exposure to cadmium and copper ions.
Biometals
20
93-105
2007
Neonectria lugdunensis
[The blood enzymatic redox system of glutathione in patients with lymphosarcoma (non-hodgkin's lymphoma]
Klin Lab Diagn
18-20, 37
2009
Homo sapiens
Gillham, DJ; Dodge, AD
Hydrogen-peroxide-scavenging systems within pea chloroplasts : A quantitative study.
Planta
167
246-51
1986
Pisum sativum, plant
Dias, CV; Mendes, JS; Dos Santos, AC; Pirovani, CP; da Silva Gesteira, A; Micheli, F; Gramacho, KP; Hammerstone, J; Mazzafera, P; de Mattos Cascardo, JC
Hydrogen peroxide formation in cacao tissues infected by the hemibiotrophic fungus Moniliophthora perniciosa.
Plant Physiol Biochem
49
917-22
2011
Theobroma cacao, Moniliophthora perniciosa, plant
Kumar, A; Bimolata, W; Kannan, M; Kirti, PB; Qureshi, IA; Ghazi, IA
Comparative proteomics reveals differential induction of both biotic and abiotic stress response associated proteins in rice during Xanthomonas oryzae pv. oryzae infection.
Funct Integr Genomics
2015
Oryza sativa
Yan, CH; Chan, KM
Cloning of zebrafish metallothionein gene and characterization of its gene promoter region in HepG2 cell line.
Biochim Biophys Acta
1679
47-58
2004
Danio rerio
Gonzalez de Aguilar, JL; Niederhauser-Wiederkehr, C; Halter, B; De Tapia, M; Di Scala, F; Demougin, P; Dupuis, L; Primig, M; Meininger, V; Loeffler, JP
Gene profiling of skeletal muscle in an amyotrophic lateral sclerosis mouse model.
Physiol Genomics
32
207-18
2008
Mus sp.
An, HM; Chen, LG; Fan, WG; Liu, QL
[Relationship between ascorbic acid accumulation and related enzyme activities in fruit of Rosa roxburghii Tratt]
Zhi Wu Sheng Li Yu Fen Zi Sheng Wu Xue Xue Bao
31
431-6
2005
Rosa roxburghii
Hu, L; Li, Y; Wu, Y; Lv, J; Dawuda, MM; Tang, Z; Liao, W; Caldern-Urrea, A; Xie, J; Yu, J
Nitric Oxide Is Involved in the Regulation of the Ascorbate-Glutathione Cycle Induced by the Appropriate Ammonium: Nitrate to Mitigate Low Light Stress in Brassica pekinensis.
Plants (Basel)
8
2019
Brassica rapa subsp. pekinensis
Li, N; Cao, B; Chen, Z; Xu, K
Root morphology ion absorption and antioxidative defense system of two Chinese cabbage cultivars (Brassica rapa L.) reveal the different adaptation mechanisms to salt and alkali stress.
Protoplasma
2021
Felis catus
Xie, Y; Liu, J; Benbrahim-Tallaa, L; Ward, JM; Logsdon, D; Diwan, BA; Waalkes, MP
Aberrant DNA methylation and gene expression in livers of newborn mice transplacentally exposed to a hepatocarcinogenic dose of inorganic arsenic.
Toxicology
236
7-15
2007
Mus musculus
Chen, Z; Leskinen, H; Liimatta, E; Sormunen, RT; Miinalainen, IJ; Hassinen, IE; Hiltunen, JK
Myocardial Overexpression of Mecr, a Gene of Mitochondrial FAS II Leads to Cardiac Dysfunction in Mouse.
PLoS ONE
4
e5589
2009
Mus musculus, Mus sp., Mammalia
Nishikawa, F; Kato, M; Hyodo, H; Ikoma, Y; Sugiura, M; Yano, M
Ascorbate metabolism in harvested broccoli.
J Exp Bot
54
2439-48
2003
Brassica oleracea var. italica
Kuzniak, E; Skłodowska, M
The effect of Botrytis cinerea infection on the antioxidant profile of mitochondria from tomato leaves.
J Exp Bot
55
605-12
2004
Botrytis cinerea
Qin, AG; Gao, JJ; Yu, XC
[Effects of high- and low temperature stresses on ascorbic acid metabolism system in potato leaves]
Ying Yong Sheng Tai Xue Bao
20
2964-70
2009
Solanum tuberosum
De Laurenzi, V; Melino, G; Savini, I; Annicchiarico-Petruzzelli, M; Finazzi-Agrò, A; Avigliano, L
Cell death by oxidative stress and ascorbic acid regeneration in human neuroectodermal cell lines.
Eur J Cancer
31A
463-6
1995
Homo sapiens
Tao, DL; Oquist, G; Wingsle, G
Active oxygen scavengers during cold acclimation of Scots pine seedlings in relation to freezing tolerance.
Cryobiology
37
38-45
1998
Lethrinidae
Jimenez, A; Hernandez, JA; Pastori, G; del Rio LA, ; Sevilla, F
Role of the ascorbate-glutathione cycle of mitochondria and peroxisomes in the senescence of pea leaves
Plant Physiol
118
1327-35
1998
Pisum sativum
Ye, B; Gressel, J
Transient, oxidant-induced antioxidant transcript and enzyme levels correlate with greater oxidant-resistance in paraquat-resistant Conyza bonariensis.
Planta
211
50-61
2000
Conyza bonariensis
Schwanz, P; Polle, A
Differential stress responses of antioxidative systems to drought in pendunculate oak (Quercus robur) and maritime pine (Pinus pinaster) grown under high CO(2) concentrations.
J Exp Bot
52
133-43
2001
Pinus pinaster, plant
Hernández, JA; Talavera, JM; Martínez-Gómez, P; Dicenta, F; Sevilla, F
Response of antioxidative enzymes to plum pox virus in two apricot cultivars.
Physiol Plant
111
313-321
2001
Felis catus, Porcine parvovirus
Ushimaru, T; Kanematsu, S; Katayama, M; Tsuji, H
Antioxidative enzymes in seedlings of Nelumbo nucifera germinated under water.
Physiol Plant
112
39-46
2001
Nelumbo nucifera, Lotus, Oryza sativa
Tommasi, F; Paciolla, C; de Pinto, MC; De Gara, L
A comparative study of glutathione and ascorbate metabolism during germination of Pinus pinea L. seeds.
J Exp Bot
52
1647-54
2001
Pinus pinea
Hernández, JA; Ferrer, MA; Jiménez, A; Barceló, AR; Sevilla, F
Antioxidant systems and O(2)(.-)/H(2)O(2) production in the apoplast of pea leaves. Its relation with salt-induced necrotic lesions in minor veins.
Plant Physiol
127
817-31
2001
Pisum sativum
Jimenez, A; Hernandez, JA; Del Rio, LA; Sevilla, F
Evidence for the Presence of the Ascorbate-Glutathione Cycle in Mitochondria and Peroxisomes of Pea Leaves.
Plant Physiol
114
275-284
1997
Pisum sativum, Electron, plant
Dalton, DA; Baird, LM; Langeberg, L; Taugher, CY; Anyan, WR; Vance, CP; Sarath, G
Subcellular Localization of Oxygen Defense Enzymes in Soybean (Glycine max [L.] Merr.) Root Nodules.
Plant Physiol
102
481-489
1993
plant
De Gara, L; de Pinto, MC; Moliterni, VM; D'Egidio, MG
Redox regulation and storage processes during maturation in kernels of Triticum durum.
J Exp Bot
54
249-58
2003
Triticum turgidum subsp. durum
Zhang, L; Zeng, F; Xiao, R
Effect of lanthanum ions (La3+) on the reactive oxygen species scavenging enzymes in wheat leaves.
Biol Trace Elem Res
91
243-52
2003
Triticum aestivum
Gechev, T; Willekens, H; Van Montagu, M; Inzé, D; Van Camp, W; Toneva, V; Minkov, I
Different responses of tobacco antioxidant enzymes to light and chilling stress.
J Plant Physiol
160
509-15
2003
Nicotiana tabacum
Andrews, PK; Fahy, DA; Foyer, CH
Relationships between fruit exocarp antioxidants in the tomato (Lycopersicon esculentum) high pigment-1 mutant during development.
Physiol Plant
120
519-528
2004
Solanum lycopersicum, Felis catus
Chaparzadeh, N; D'Amico, ML; Khavari-Nejad, RA; Izzo, R; Navari-Izzo, F
Antioxidative responses of Calendula officinalis under salinity conditions.
Plant Physiol Biochem
42
695-701
2004
Calendula officinalis
Chen, LS; Qi, YP; Liu, XH
Effects of aluminum on light energy utilization and photoprotective systems in citrus leaves.
Ann Bot (Lond)
96
35-41
2005
Citrus
Kuzniak, E; Skłodowska, M
Fungal pathogen-induced changes in the antioxidant systems of leaf peroxisomes from infected tomato plants.
Planta
222
192-200
2005
Botrytis cinerea, Felis catus, plant, Solanum lycopersicum
Fatima, RA; Ahmad, M
Certain antioxidant enzymes of Allium cepa as biomarkers for the detection of toxic heavy metals in wastewater.
Sci Total Environ
346
256-73
2005
Allium cepa
Sharma, P; Dubey, RS
Involvement of oxidative stress and role of antioxidative defense system in growing rice seedlings exposed to toxic concentrations of aluminum.
Plant Cell Rep
26
2027-38
2007
Oryza sativa
Li, P; Cheng, L
The shaded side of apple fruit becomes more sensitive to photoinhibition with fruit development.
Physiol Plant
134
282-92
2008
Malus domestica
Murshed, R; Lopez-Lauri, F; Sallanon, H
Microplate quantification of enzymes of the plant ascorbate-glutathione cycle.
Anal Biochem
383
320-2
2008
plant, Solanum lycopersicum
Pérez-López, U; Robredo, A; Lacuesta, M; Sgherri, C; Muñoz-Rueda, A; Navari-Izzo, F; Mena-Petite, A
The oxidative stress caused by salinity in two barley cultivars is mitigated by elevated CO2.
Physiol Plant
135
29-42
2009
Felis catus, Hordeum vulgare
Bai, R; Ma, F; Liang, D; Zhao, X
Phthalic acid induces oxidative stress and alters the activity of some antioxidant enzymes in roots of Malus prunifolia.
J Chem Ecol
35
488-94
2009
Malus prunifolia, Malus domestica
Wang, H; Feng, T; Peng, X; Yan, M; Tang, X
Up-regulation of chloroplastic antioxidant capacity is involved in alleviation of nickel toxicity of Zea mays L. by exogenous salicylic acid.
Ecotoxicol Environ Saf
2009
Zea mays
Zhou, YH; Zhang, YY; Zhao, X; Yu, HJ; Shi, K; Yu, JQ
Impact of Light Variation on Development of Photoprotection, Antioxidants, and Nutritional Value in Lactuca sativa L.
J Agric Food Chem
2009
Electron
Belmonte, MF; Stasolla, C
Altered HBK3 expression affects glutathione and ascorbate metabolism during the early phases of Norway spruce (Picea abies) somatic embryogenesis.
Plant Physiol Biochem
47
904-11
2009
Picea abies, plant
Pandey, V; Dixit, V; Shyam, R
Chromium effect on ROS generation and detoxification in pea (Pisum sativum) leaf chloroplasts.
Protoplasma
236
85-95
2009
Pisum sativum, Electron
Ruan, YN; He, XY; Chen, W; Chen, ZJ; Sun, Y
[Effects of elevated O3 concentration on anti-oxidative enzyme activities in Pinus tabulaeformis]
Ying Yong Sheng Tai Xue Bao
20
1032-7
2009
Pinus tabuliformis
Saruhan, N; Terzi, R; Saglam, A; Kadioglu, A
The relationship between leaf rolling and ascorbate-glutathione cycle enzymes in apoplastic and symplastic areas of Ctenanthe setosa subjected to drought stress.
Biol Res
42
315-26
2009
Areas, Ctenanthe setosa
Martínez Domínguez, D; Córdoba García, F; Canalejo Raya, A; Torronteras Santiago, R
Cadmium-induced oxidative stress and the response of the antioxidative defense system in Spartina densiflora.
Physiol Plant
2010
plant, Salvia densiflora, Sporobolus densiflorus
Chen, F; Wang, F; Wu, F; Mao, W; Zhang, G; Zhou, M
Modulation of exogenous glutathione in antioxidant defense system against Cd stress in the two barley genotypes differing in Cd tolerance.
Plant Physiol Biochem
48
663-72
2010
Hordeum vulgare, Felis catus
Drazkiewicz, M; Skrzy?ska-Polit, E; Krupa, Z
Effect of BSO-supplemented heavy metals on antioxidant enzymes in Arabidopsis thaliana.
Ecotoxicol Environ Saf
73
1362-9
2010
Arabidopsis thaliana, plant
Morina, F; Jovanovic, L; Mojovic, M; Vidovic, M; Pankovic, D; Veljovic Jovanovic, S
Zinc-induced oxidative stress in Verbascum thapsus is caused by an accumulation of reactive oxygen species and quinhydrone in the cell wall.
Physiol Plant
140
209-24
2010
Verbascum thapsus
Mishra, S; Jha, AB; Dubey, RS
Arsenite treatment induces oxidative stress, upregulates antioxidant system, and causes phytochelatin synthesis in rice seedlings.
Protoplasma
2010
Oryza sativa, Oryza sativa Indica Group
Rai, A; Tripathi, P; Dwivedi, S; Dubey, S; Shri, M; Kumar, S; Tripathi, PK; Dave, R; Kumar, A; Singh, R; Adhikari, B; Bag, M; Tripathi, RD; Trivedi, PK; Chakrabarty, D; Tuli, R
Arsenic tolerances in rice (Oryza sativa) have a predominant role in transcriptional regulation of a set of genes including sulphur assimilation pathway and antioxidant system.
Chemosphere
82
986-95
2011
Oryza sativa
Xu, XD; Sun, Y; Guo, XQ; Sun, B; Zhang, J
[Effects of exogenous melatonin on ascorbate metabolism system in cucumber seedlings under high temperature stress].
Ying Yong Sheng Tai Xue Bao
21
2580-6
2010
Cucumis sativus
Liu, YJ; Yuan, Y; Liu, YY; Liu, Y; Fu, JJ; Zheng, J; Wang, GY
Gene families of maize glutathione-ascorbate redox cycle respond differently to abiotic stresses.
J Plant Physiol
169
183-92
2012
Zea mays
Wang, S; Liang, D; Li, C; Hao, Y; Ma, F; Shu, H
Influence of drought stress on the cellular ultrastructure and antioxidant system in leaves of drought-tolerant and drought-sensitive apple rootstocks.
Plant Physiol Biochem
51
81-9
2012
Malus hupehensis, Malus prunifolia
Cascia, G; Bulley, SM; Punter, M; Bowen, J; Rassam, M; Schotsmans, WC; Larrigaudire, C; Johnston, JW
Investigation of ascorbate metabolism during inducement of storage disorders in pear.
Physiol Plant
2012
Pyrus communis, Malus domestica, Pyrus
Wu, C; Qin, S; Yuan, Y; Chen, P; Lin, S
[Effect of water deficit on gene expression of enzymes related with hydrogen peroxide detoxification system in Scutellaria baicalensis].
Zhongguo Zhong Yao Za Zhi
37
186-8
2012
Scutellaria baicalensis, Scutellaria
Pyngrope, S; Bhoomika, K; Dubey, RS
Reactive oxygen species, ascorbate-glutathione pool, and enzymes of their metabolism in drought-sensitive and tolerant indica rice (Oryza sativa L.) seedlings subjected to progressing levels of water deficit.
Protoplasma
2012
Oryza sativa
Subramanyam, K; Arun, M; Mariashibu, TS; Theboral, J; Rajesh, M; Singh, NK; Manickavasagam, M; Ganapathi, A
Overexpression of tobacco osmotin (Tbosm) in soybean conferred resistance to salinity stress and fungal infections.
Planta
2012
Glycine max, Felis catus
Singh, VP; Srivastava, PK; Prasad, SM
Differential effect of UV-B radiation on growth, oxidative stress and ascorbate-glutathione cycle in two cyanobacteria under copper toxicity.
Plant Physiol Biochem
61
61-70
2012
Cyanobacteria
Luo, N; Yu, X; Liu, J; Jiang, Y
Nucleotide diversity and linkage disequilibrium in antioxidant genes of Brachypodium distachyon.
Plant Sci
197
122-9
2012
Felis catus
Gallie, DR
The role of L-ascorbic acid recycling in responding to environmental stress and in promoting plant growth.
J Exp Bot
64
433-43
2013
plant
Omoto, E; Nagao, H; Taniguchi, M; Miyake, H
Localization of reactive oxygen species and change of antioxidant capacities in mesophyll and bundle sheath chloroplasts of maize under salinity.
Physiol Plant
2012
Zea mays, Indicator, Electron
Shu, S; Yuan, LY; Guo, SR; Sun, J; Yuan, YH
Effects of exogenous spermine on chlorophyll fluorescence, antioxidant system and ultrastructure of chloroplasts in Cucumis sativus L. under salt stress.
Plant Physiol Biochem
63
209-16
2013
Cucumis sativus, plant
Harrach, BD; Baltruschat, H; Barna, B; Fodor, J; Kogel, KH
The mutualistic fungus Piriformospora indica protects barley roots from a loss of antioxidant capacity caused by the necrotrophic pathogen Fusarium culmorum.
Mol Plant Microbe Interact
2013
Hordeum vulgare, Fusarium culmorum, Serendipita indica, Fusarium, Pseudomonas indica, plant
Murshed, R; Lopez-Lauri, F; Sallanon, H
Effect of water stress on antioxidant systems and oxidative parameters in fruits of tomato (Solanum lycopersicon L, cv. Micro-tom).
Physiol Mol Biol Plants
19
363-78
2013
Felis catus, Solanum lycopersicum, Solanum subgen. Lycopersicon
Murshed, R; Lopez-Lauri, F; Sallanon, H
Effect of salt stress on tomato fruit antioxidant systems depends on fruit development stage.
Physiol Mol Biol Plants
20
15-29
2014
Solanum lycopersicum, Felis catus
Yin, G; Xin, X; Song, C; Chen, X; Zhang, J; Wu, S; Li, R; Liu, X; Lu, X
Activity levels and expression of antioxidant enzymes in the ascorbate-glutathione cycle in artificially aged rice seed.
Plant Physiol Biochem
80C
1-9
2014
Oryza sativa
Darwish, M; Lopez-Lauri, F; El Maataoui, M; Urban, L; Sallanon, H
Pretreatment with alternation of light/dark periods improves the tolerance of tobacco (Nicotiana tabacum) to clomazone herbicide.
J Photochem Photobiol B
134
49-56
2014
Electron, Nicotiana tabacum, plant
Yu, XZ; Zhang, XH; Yue, DM
Alternation of antioxidative enzyme gene expression in rice seedlings exposed to methylene blue.
Environ Sci Pollut Res Int
2014
Oryza sativa
Xia, F; Wang, X; Li, M; Mao, P
Mitochondrial structural and antioxidant system responses to aging in oat (Avena sativa L.) seeds with different moisture contents.
Plant Physiol Biochem
94
122-9
2015
Avena sp.
Rosalie, R; Joas, J; Deytieux-Belleau, C; Vulcain, E; Payet, B; Dufoss, L; Lchaudel, M
Antioxidant and enzymatic responses to oxidative stress induced by pre-harvest water supply reduction and ripening on mango (Mangifera indica L. cv. 'Cogshall') in relation to carotenoid content.
J Plant Physiol
184
68-78
2015
Felis catus
Rai, N; Rai, KK; Venkataravanappa, V; Saha, S
Molecular Approach Coupled with Biochemical Attributes to Elucidate the Presence of DYMV in Leaf Samples of Lablab purpureus. L Genotypes.
Appl Biochem Biotechnol
178
876-90
2016
Felis catus
Sytykiewicz, H
Expression Patterns of Genes Involved in Ascorbate-Glutathione Cycle in Aphid-Infested Maize (Zea mays L.) Seedlings.
Int J Mol Sci
17
2016
Zea mays, Aphididae, Rhopalosiphum padi, Sitobion avenae
Wang, J; Wu, B; Yin, H; Fan, Z; Li, X; Ni, S; He, L; Li, J
Overexpression of CaAPX Induces Orchestrated Reactive Oxygen Scavenging and Enhances Cold and Heat Tolerances in Tobacco.
Biomed Res Int
2017
4049534
2017
Felis catus
Zhou, Y; Yang, Z; Gao, L; Liu, W; Liu, R; Zhao, J; You, J
Changes in element accumulation, phenolic metabolism, and antioxidative enzyme activities in the red-skin roots of Panax ginseng.
J Ginseng Res
41
307-315
2017
Panax ginseng
Rosalie, R; Lchaudel, M; Dhuique-Mayer, C; Dufoss, L; Joas, J
Antioxidant and enzymatic responses to oxidative stress induced by cold temperature storage and ripening in mango (Mangifera indica L. cv. 'Cogshall') in relation to carotenoid content.
J Plant Physiol
224-225
75-85
2018
Felis catus
Huang, C; Qin, N; Sun, L; Yu, M; Hu, W; Qi, Z
Selenium Improves Physiological Parameters and Alleviates Oxidative Stress in Strawberry Seedlings under Low-Temperature Stress.
Int J Mol Sci
19
2018
Fragaria x ananassa
Yan, Y; Pan, C; Du, Y; Li, D; Liu, W
Exogenous salicylic acid regulates reactive oxygen species metabolism and ascorbate-glutathione cycle in Nitraria tangutorum Bobr. under salinity stress.
Physiol Mol Biol Plants
24
577-589
2018
Nitraria tangutorum
Yuan, M; Xu, YC; Niu, YQ; Zhou, H; An, YL; Jin, QJ; Wang, YJ
Effects of ethylene and NO on AsA-GSH in lotus under cadmium stress.
Ying Yong Sheng Tai Xue Bao
29
3433-3440
2018
Lotus
Avashthi, H; Pathak, RK; Pandey, N; Arora, S; Mishra, AK; Gupta, VK; Ramteke, PW; Kumar, A
Transcriptome-wide identification of genes involved in Ascorbate-Glutathione cycle (Halliwell-Asada pathway) and related pathway for elucidating its role in antioxidative potential in finger millet (Eleusine coracana (L.)).
3 Biotech
8
499
2018
Eleusine coracana, Oryza sativa
Acosta-Motos, JR; Noguera-Vera, L; Barba-Espn, G; Piqueras, A; Hernndez, JA
Antioxidant Metabolism and Chlorophyll Fluorescence during the Acclimatisation to Ex Vitro Conditions of Micropropagated Stevia rebaudiana Bertoni Plants.
Antioxidants (Basel)
8
2019
Stevia
Elbasan, F; Ozfidan-Konakci, C; Yildiztugay, E; Kucukoduk, M
Rare-earth element scandium improves stomatal regulation and enhances salt and drought stress tolerance by up-regulating antioxidant responses of Oryza sativa.
Plant Physiol Biochem
152
157-169
2020
Oryza sativa
Yu, J; Cang, J; Lu, Q; Fan, B; Xu, Q; Li, W; Wang, X
ABA enhanced cold tolerance of wheat 'dn1' via increasing ROS scavenging system.
Plant Signal Behav
15
1780403
2020
Felis catus
Hernndez, JA; Aguilar, AB; Portillo, B; Lpez-Gmez, E; Beneyto, JM; Garca-Legaz, MF
The effect of calcium on the antioxidant enzymes from salt-treated loquat and anger plants.
Funct Plant Biol
30
1127-1137
2003
Rhaphiolepis bibas
Liu, N; Li, J; Lv, J; Yu, J; Xie, J; Wu, Y; Tang, Z
Melatonin alleviates imidacloprid phytotoxicity to cucumber (Cucumis sativus L.) through modulating redox homeostasis in plants and promoting its metabolism by enhancing glutathione dependent detoxification.
Ecotoxicol Environ Saf
217
112248
2021
Cucumis sativus
Puthiyottil, P; Akkara, Y
Pre treatment with Bacillus subtilis mitigates drought induced photo-oxidative damages in okra by modulating antioxidant system and photochemical activity.
Physiol Mol Biol Plants
27
945-957
2021
Abelmoschus esculentus
Costa, JH; Roque, ALM; Aziz, S; Dos Santos, CP; Germano, TA; Batista, MC; Thiers, KLL; da Cruz Saraiva, KD; Arnholdt-Schmitt, B
Genome-wide identification of ascorbate-glutathione cycle gene families in soybean (Glycine max) reveals gene duplication events and specificity of gene members linked to development and stress conditions.
Int J Biol Macromol
187
528-543
2021
Glycine max
Hou, Y; Li, Z; Zheng, Y; Jin, P
Effects of CaCl2 Treatment Alleviates Chilling Injury of Loquat Fruit (Eribotrya japonica) by Modulating ROS Homeostasis.
Foods
10
2021
Rhaphiolepis bibas
Wang, J; Wang, D; Zhu, M; Li, F
Exogenous 6-Benzyladenine Improves Waterlogging Tolerance in Maize Seedlings by Mitigating Oxidative Stress and Upregulating the Ascorbate-Glutathione Cycle.
Front Plant Sci
12
680376
2021
Zea mays
Youssef SA;Tartoura KAH
Compost enhances plant resistance against the bacterial wilt pathogen Ralstonia solanacearum via up-regulation of ascorbate-glutathione redox cycle
European journal of plant pathology
137
821-834
2013
Solanum tuberosum, Ralstonia solanacearum, plant, Ralstonia
Omoto E;Nagao H;Taniguchi M;Miyake H
Localization of reactive oxygen species and change of antioxidant capacities in mesophyll and bundle sheath chloroplasts of maize under salinity
Physiologia plantarum
149
1-12
2013
Electron, Indicator, Zea mays
Luo N;Yu X;Liu J;Jiang Y
Nucleotide diversity and linkage disequilibrium in antioxidant genes of Brachypodium distachyon
Plant science : an international journal of experimental plant biology
197
122-129
2012
Felis catus
Morina F;Jovanovic L;Mojovic M;Vidovic M;Pankovic D;Veljovic Jovanovic S
Zinc-induced oxidative stress in Verbascum thapsus is caused by an accumulation of reactive oxygen species and quinhydrone in the cell wall
Physiologia plantarum
140
209-224
2010
Verbascum thapsus
Martnez Domnguez D;Crdoba Garca F;Canalejo Raya A;Torronteras Santiago R
Cadmium-induced oxidative stress and the response of the antioxidative defense system in Spartina densiflora
Physiologia plantarum
139
289-302
2010
plant, Salvia densiflora, Sporobolus densiflorus
Sofo A;Tuzio AC;Dichio B;Xiloyannis C
Influence of water deficit and rewatering on the components of the ascorbate-glutathione cycle in four interspecific Prunus hybrids.
Plant science : an international journal of experimental plant biology
169
403-412
2005
Prunus
Ignacio, S; Moore, DH; Smith, AP; Lee, NM
Effect of Neuroprotective Drugs on Gene Expression in G93A/SOD1 Mice.
Ann N Y Acad Sci
1053
121-36
2005
Metazoa
Savini, I; Duflot, S; Avigliano, L
Dehydroascorbic acid uptake in a human keratinocyte cell line (HaCaT) is glutathione-independent.
Biochem J
345 Pt 3
665-72
2000
Homo sapiens
Subramanian, KN; Reddy, VB; Weissman, SM
Occurrence of reiterated sequences in an untranslated region of Simian virus 40 DNA determined by nucleotide sequence analysis.
Cell
10
497-507
1977
Macaca mulatta polyomavirus 1
Gerasimov, AM; Koroleva, LA; Ivanova, LI; Panchenko, LF
[Glutathione: dehydroascorbate-oxidoreductase activity in rat tissues]
Vopr Med Khim
25
447-51
0
Rattus
Gerasimov, AM; Koroleva, LA; Brusov, OS; Olfer'ev, AM; Antonenkov, VD; Panchenko, LF
[Enzymatic mechanisms of inhibition of peroxidative oxidation in different regions of rat brain]
Vopr Med Khim
22
89-94
0
Rattus
Ugwu, SO; Blanchard, J
High-performance liquid chromatographic assay for the alpha-melanotropin[4,10] fragment analogue (Melanotan-II) in rat plasma.
J Chromatogr
584
175-80
1992
Rattus
Mehra, RK; Thorvaldsen, JL; Macreadie, IG; Winge, DR
Disruption analysis of metallothionein-encoding genes in Candida glabrata.
Gene
114
75-80
1992
Calpurnia glabrata
Chalifour, LE; Mes-Masson, AM; Gomes, ML; Wang, NS
Testicular adenoma and seminal vesicle engorgement in polyomavirus large-T antigen transgenic mice.
Mol Carcinog
5
178-89
1992
Mus musculus, Polyomavirus sp.
Hartmann, HJ; Li, YJ; Weser, U
Analogous copper(I) coordination in metallothionein from yeast and the separate domains of the mammalian protein.
Biometals
5
187-91
1992
Saccharomyces cerevisiae, Rattus
Huper, G; Marks, JR; Wiener, JR; Iglehart, JD
Relative promoter activity in human mammary epithelial cells assayed by transient expression.
In Vitro Cell Dev Biol
28A
730-4
0
Mus musculus
Balbis, A; Dellacha, JM; Calandra, RS; Bartke, A; Turyn, D
Down regulation of masked and unmasked insulin receptors in the liver of transgenic mice expressing bovine growth hormone gene.
Life Sci
51
771-8
1992
Bos taurus, Mus musculus
Messerle, BA; Schäffer, A; Vasák, M; Kägi, JH; Wüthrich, K
Comparison of the solution conformations of human [Zn7]-metallothionein-2 and [Cd7]-metallothionein-2 using nuclear magnetic resonance spectroscopy.
J Mol Biol
225
433-43
1992
Homo sapiens
Kershaw, WC; Klaassen, CD
Degradation and metal composition of hepatic isometallothioneins in rats.
Toxicol Appl Pharmacol
112
24-31
1992
Rattus, animal
Peng, S; Shan, XQ; Zheng, Y; Jin, LZ; Xu, WB
Determination of dietary cadmium-induced metallothioneins in rabbit kidneys and cadmium in metallothioneins by anion-exchange high-performance liquid chromatography coupled with graphite furnace atomic absorption spectrometry.
J Chromatogr
572
73-84
1991
Oryctolagus cuniculus
Sato, M
Dose-dependent increases in metallothionein synthesis in the lung and liver of paraquat-treated rats.
Toxicol Appl Pharmacol
107
98-105
1991
Rattus
Shiraishi, N; Taguchi, T; Kinebuchi, H
Metallothionein messenger RNA levels in the macular mutant mouse: an animal model of Menkes' kinky-hair disease.
Biol Neonate
60
52-61
1991
Mus sp.
De, SK; Enders, GC; Andrews, GK
Metallothionein mRNA stability in chicken and mouse cells.
Biochim Biophys Acta
1090
223-9
1991
Mus musculus
Andrews, GK; Huet-Hudson, YM; Paria, BC; McMaster, MT; De, SK; Dey, SK
Metallothionein gene expression and metal regulation during preimplantation mouse embryo development (MT mRNA during early development).
Dev Biol
145
13-27
1991
Mus musculus
Mittler, R; Nir, M; Tel-Or, E
Antiperoxidative enzymes in Retama and their seasonal variation.
Free Radic Res Commun
14
17-24
1991
Retama
Yang, YF; Wells, WW
Identification and characterization of the functional amino acids at the active center of pig liver thioltransferase by site-directed mutagenesis.
J Biol Chem
266
12759-65
1991
Sus scrofa
Kershaw, WC; Klaassen, CD
Cadmium-induced elevation of hepatic isometallothionein concentrations in inbred strains of mice.
Chem Biol Interact
78
269-82
1991
Mus sp.
De, SK; Enders, GC; Andrews, GK
High levels of metallothionein messenger RNAs in male germ cells of the adult mouse.
Mol Endocrinol
5
628-36
1991
Mus musculus
Li, YJ; Zhang, LS; Bayer, E; Oelkrug, D; Weser, U
Comparative luminescence of rat liver Cu-thionein and its chemically synthesized alpha-domain.
Z Naturforsch [C]
45
1193-6
0
Rattus
Shi, YX; Ji, XD; Li, GS; Shu, YM
The study on transgenic mice.
Chin J Biotechnol
6
189-97
1990
Mus musculus, Homo sapiens
Chalifour, LE; Gomes, ML; Wang, NS; Mes-Masson, AM
Polyomavirus large T-antigen expression in heart of transgenic mice causes cardiomyopathy.
Oncogene
5
1719-26
1990
Mus musculus
Fan, CY; Potter, PM; Rafferty, J; Watson, AJ; Cawkwell, L; Searle, PF; O'Connor, PJ; Margison, GP
Expression of a human O6-alkylguanine-DNA-alkyltransferase cDNA in human cells and transgenic mice.
Nucleic Acids Res
18
5723-7
1990
Homo sapiens, Mus musculus
Behringer, RR; Cate, RL; Froelick, GJ; Palmiter, RD; Brinster, RL
Abnormal sexual development in transgenic mice chronically expressing müllerian inhibiting substance.
Nature
345
167-70
1990
Mus musculus, Homo sapiens
Kershaw, WC; Lehman-McKeeman, LD; Klaassen, CD
Hepatic isometallothioneins in mice: induction in adults and postnatal ontogeny.
Toxicol Appl Pharmacol
104
267-75
1990
Mus musculus
Messerle, BA; Schäffer, A; Vasák, M; Kägi, JH; Wüthrich, K
Three-dimensional structure of human [113Cd7]metallothionein-2 in solution determined by nuclear magnetic resonance spectroscopy.
J Mol Biol
214
765-79
1990
Homo sapiens, Oryctolagus cuniculus, Rattus
Brar, AK; Brinster, RL; Frohman, LA
Immunohistochemical analysis of human growth hormone-releasing hormone gene expression in transgenic mice.
Endocrinology
125
801-9
1989
Homo sapiens, Mus musculus
McGeady, ML; Kerby, S; Shankar, V; Ciardiello, F; Salomon, D; Seidman, M
Infection with a TGF-alpha retroviral vector transforms normal mouse mammary epithelial cells but not normal rat fibroblasts.
Oncogene
4
1375-82
1989
Mus musculus, Homo sapiens
Tam, YC; Hassan, M; Chopra, A; Thirion, JP
Cloning, nucleotide sequence and molecular evolution of a rabbit processed metallothionein MT-2 pseudogene.
Biochem Biophys Res Commun
156
1403-10
1988
Oryctolagus cuniculus
Grider, A; Kao, KJ; Klein, PA; Cousins, RJ
Enzyme-linked immunosorbent assay for human metallothionein: correlation of induction with infection.
J Lab Clin Med
113
221-8
1989
Homo sapiens, Ovis aries
Lieberman, HB; Rabin, M; Barker, PE; Ruddle, FH; Varshney, U; Gedamu, L
Human metallothionein-II processed gene is located in region p11----q21 of chromosome 4.
Cytogenet Cell Genet
39
109-15
1985
Homo sapiens, Mus musculus
Higham, DP; Nicholson, JK; Overnell, J; Sadler, PJ
NMR studies of crab and plaice metallothioneins.
Environ Health Perspect
65
157-65
1986
Scylla serrata, Oryctolagus cuniculus
Murooka, Y; Nagaoka, T
Expression of cloned monkey metallothionein in Escherichia coli.
Appl Environ Microbiol
53
204-7
1987
Escherichia coli
Schultze, P; Wörgötter, E; Braun, W; Wagner, G; Vasák, M; Kägi, JH; Wüthrich, K
Conformation of [Cd7]-metallothionein-2 from rat liver in aqueous solution determined by nuclear magnetic resonance spectroscopy.
J Mol Biol
203
251-68
1988
Rattus, Oryctolagus cuniculus
Huber, KL; Cousins, RJ
Maternal zinc deprivation and interleukin-1 influence metallothionein gene expression and zinc metabolism of rats.
J Nutr
118
1570-6
1988
Rattus
Harewood, KR; Wilson, DS; Higdon, RC; Tsaparikos, KE; Brunson, KW
Regulated expression of the human mutant ras gene after transfection of BALB/c mouse embryo fibroblast cells.
J Natl Cancer Inst
80
122-6
1988
Mus musculus
Wei, DY; Andrews, GK
Molecular cloning of chicken metallothionein. Deduction of the complete amino acid sequence and analysis of expression using cloned cDNA.
Nucleic Acids Res
16
537-53
1988
Gallus gallus, Mammalia
Lehman-McKeeman, LD; Andrews, GK; Klaassen, CD
Mechanisms of regulation of rat hepatic metallothionein-I and metallothionein-II levels following administration of zinc.
Toxicol Appl Pharmacol
92
1-9
1988
Mus musculus
Lehman-McKeeman, LD; Andrews, GK; Klaassen, CD
Ontogeny and induction of hepatic isometallothioneins in immature rats.
Toxicol Appl Pharmacol
92
10-7
1988
Rattus, Mus musculus
Lehman-McKeeman, LD; Andrews, GK; Klaassen, CD
Induction of hepatic metallothioneins determined at isoprotein and messenger RNA levels in glucocorticoid-treated rats.
Biochem J
249
429-33
1988
Rattus, Mus musculus
Peterson, MG; Mercer, JF
Differential expression of four linked sheep metallothionein genes.
Eur J Biochem
174
425-9
1988
Ovis aries
Kito, H; Ose, Y; Sato, T
Cadmium-binding protein (metallothionein) in carp.
Environ Health Perspect
65
117-24
1986
Cyprinus carpio, Oryctolagus cuniculus
Lehman-McKeeman, LD; Klaassen, CD
Induction of metallothionein-I and metallothionein-II in rats by cadmium and zinc.
Toxicol Appl Pharmacol
88
195-202
1987
Rattus
Tel-Or, E; Huflejt, M; Packer, L
The role of glutathione and ascorbate in hydroperoxide removal in cyanobacteria.
Biochem Biophys Res Commun
132
533-9
1985
Cyanobacteria, Synechococcus, Desmonostoc muscorum
Karin, M; Eddy, RL; Henry, WM; Haley, LL; Byers, MG; Shows, TB
Human metallothionein genes are clustered on chromosome 16.
Proc Natl Acad Sci U S A
81
5494-8
1984
Homo sapiens
Searle, PF; Davison, BL; Stuart, GW; Wilkie, TM; Norstedt, G; Palmiter, RD
Regulation, linkage, and sequence of mouse metallothionein I and II genes.
Mol Cell Biol
4
1221-30
1984
Mus musculus, Primates, Homo sapiens, Rodentia
Karin, M; Cathala, G; Nguyen-Huu, MC
Expression and regulation of a human metallothionein gene carried on an autonomously replicating shuttle vector.
Proc Natl Acad Sci U S A
80
4040-4
1983
Homo sapiens
Schmidt, CJ; Hamer, DH
Cloning and sequence analysis of two monkey metallothionein cDNAs.
Gene
24
137-46
1983
Platyrrhini, Homo sapiens
Takeshita, S; Losordo, DW; Kearney, M; Rossow, ST; Isner, JM
Time course of recombinant protein secretion after liposome-mediated gene transfer in a rabbit arterial organ culture model.
Lab Invest
71
387-91
1994
Homo sapiens, Mus musculus
Rising, L; Vitarella, D; Kimelberg, HK; Aschner, M
Metallothionein induction in neonatal rat primary astrocyte cultures protects against methylmercury cytotoxicity.
J Neurochem
65
1562-8
1995
Rattus
Neale, GA; Rehg, JE; Goorha, RM
Ectopic expression of rhombotin-2 causes selective expansion of CD4-CD8- lymphocytes in the thymus and T-cell tumors in transgenic mice.
Blood
86
3060-71
1995
Mus musculus
Conlan, RS; Griffiths, LA; Napier, JA; Shewry, PR; Mantell, S; Ainsworth, C
Isolation and characterisation of cDNA clones representing the genes encoding the major tuber storage protein (dioscorin) of yam (Dioscorea cayenensis Lam.).
Plant Mol Biol
28
369-80
1995
Dioscoreaceae
Sciavolino, PJ; Vilcek, J
Regulation of metallothionein gene expression by TNF-alpha and IFN-beta in human fibroblasts.
Cytokine
7
242-50
1995
Felis catus
Lachman, HM; Papolos, DF; Boyle, A; Sheftel, G; Juthani, M; Edwards, E; Henn, FA
Alterations in glucocorticoid inducible RNAs in the limbic system of learned helpless rats.
Brain Res
609
110-6
1993
Rattus
Buffinton, GD; Doe, WF
Altered ascorbic acid status in the mucosa from inflammatory bowel disease patients.
Free Radic Res
22
131-43
1995
Homo sapiens
Kloth, DM; Chin, JL; Cherian, MG
Induction of hepatic metallothionein I in tumour-bearing mice.
Br J Cancer
71
712-6
1995
Mus sp.
Philcox, JC; Coyle, P; Michalska, A; Choo, KH; Rofe, AM
Endotoxin-induced inflammation does not cause hepatic zinc accumulation in mice lacking metallothionein gene expression.
Biochem J
308 ( Pt 2)
543-6
1995
Mus sp.
Lebel, M; Mes-Masson, AM
Sequence analysis of a novel cDNA which is overexpressed in testicular tumors from polyomavirus large T-antigen transgenic mice.
DNA Seq
5
31-9
1994
Mus musculus, Polyomavirus sp.
Hidalgo, J; García, A; Oliva, AM; Giralt, M; Gasull, T; González, B; Milnerowicz, H; Wood, A; Bremner, I
Effect of zinc, copper and glucocorticoids on metallothionein levels of cultured neurons and astrocytes from rat brain.
Chem Biol Interact
93
197-219
1994
Rattus, Homo sapiens, Hippocampus
Ma, YJ; Dissen, GA; Merlino, G; Coquelin, A; Ojeda, SR
Overexpression of a human transforming growth factor-alpha (TGF alpha) transgene reveals a dual antagonistic role of TGF alpha in female sexual development.
Endocrinology
135
1392-400
1994
Homo sapiens, Mus musculus
Yamada, K; Kato, H; Kanda, N; Fujii-Kuriyama, Y; Utakoji, T; Itoh, R
Sequence homology of Chinese hamster metallothionein genes I and II to those of the mouse and rat, and their amplification in Cd-resistant cells.
Biochim Biophys Acta
1219
581-91
1994
Cricetulus griseus, Mus musculus, Rattus
Pauwels, M; van Weyenbergh, J; Soumillion, A; Proost, P; De Ley, M
Induction by zinc of specific metallothionein isoforms in human monocytes.
Eur J Biochem
220
105-10
1994
Homo sapiens
Michalska, AE; Choo, KH
Targeting and germ-line transmission of a null mutation at the metallothionein I and II loci in mouse.
Proc Natl Acad Sci U S A
90
8088-92
1993
Mus musculus, Mus sp.
Zhou, P; Thiele, DJ
Rapid transcriptional autoregulation of a yeast metalloregulatory transcription factor is essential for high-level copper detoxification.
Genes Dev
7
1824-35
1993
[Candida] glabrata
Kobayashi, H; Uchida, Y; Ihara, Y; Nakajima, K; Kohsaka, S; Miyatake, T; Tsuji, S
Molecular cloning of rat growth inhibitory factor cDNA and the expression in the central nervous system.
Brain Res Mol Brain Res
19
188-94
1993
Rattus
McKenna, IM; Bare, RM; Waalkes, MP
Metallothionein gene expression in testicular interstitial cells and liver of rats treated with cadmium.
Toxicology
107
121-30
1996
Rattus, Metazoa
Kurasaki, M; Yamasaki, F; Suzuki-Kurasaki, M; Kojima, Y
Copper replacement of cadmium-binding alpha-fragment of metallothionein expressed in Escherichia coli.
Res Commun Mol Pathol Pharmacol
92
225-32
1996
Escherichia coli, Homo sapiens
Cowan, K; Conklin, D; Aschner, M
Metallothionein induction by bismuth in neonatal rat primary astrocyte cultures.
Brain Res
732
106-12
1996
Rattus
Gong, Q; Hart, BA
Effect of thiols on cadmium-induced expression of metallothionein and other oxidant stress genes in rat lung epithelial cells.
Toxicology
119
179-91
1997
Rattus
Kelly, EJ; Sandgren, EP; Brinster, RL; Palmiter, RD
A pair of adjacent glucocorticoid response elements regulate expression of two mouse metallothionein genes.
Proc Natl Acad Sci U S A
94
10045-50
1997
Mus musculus
Kobayashi, K; Shimada, A; Yamano, Y; Umemura, T
Molecular cloning of a canine metallothionein cDNA.
J Vet Med Sci
59
819-23
1997
Canis lupus familiaris
Kojima, S; Shimada, A; Kodan, A; Kobayashi, K; Morita, T; Yamano, Y; Umemura, T
Molecular cloning and expression of the canine metallothionein-III gene.
Can J Vet Res
62
148-51
1998
Canis lupus familiaris
Tseng, KF; Goldstein, SA
Systemic over-secretion of growth hormone in transgenic mice results in a specific pattern of skeletal modeling and adaptation.
J Bone Miner Res
13
706-15
1998
Mus musculus
Raghavachari, N; Qiao, F; Shinohara, T; Kikuchi, T; Lou, MF
Cloning, high level-expression and characterization of human lens thioltransferase.
Exp Eye Res
66
465-75
1998
Homo sapiens, Escherichia coli, Sus scrofa
Carginale, V; Scudiero, R; Capasso, C; Capasso, A; Kille, P; di Prisco, G; Parisi, E
Cadmium-induced differential accumulation of metallothionein isoforms in the Antarctic icefish, which exhibits no basal metallothionein protein but high endogenous mRNA levels.
Biochem J
332 ( Pt 2)
475-81
1998
Chondrichthyes
Arora, V; Iversen, PL; Ebadi, M
Manipulation of metallothionein expression in the regenerating rat liver using antisense oligonucleotides.
Biochem Biophys Res Commun
246
711-8
1998
Rattus
Ono, S; Cai, L; Cherian, MG
Effects of gamma radiation on levels of brain metallothionein and lipid peroxidation in transgenic mice.
Radiat Res
150
52-7
1998
Mus musculus
Carrasco, J; Hernandez, J; Bluethmann, H; Hidalgo, J
Interleukin-6 and tumor necrosis factor-alpha type 1 receptor deficient mice reveal a role of IL-6 and TNF-alpha on brain metallothionein-I and -III regulation.
Brain Res Mol Brain Res
57
221-34
1998
Rattus
Zhang, B; Satoh, M; Nishimura, N; Suzuki, JS; Sone, H; Aoki, Y; Tohyama, C
Metallothionein deficiency promotes mouse skin carcinogenesis induced by 7,12-dimethylbenz[a]anthracene.
Cancer Res
58
4044-6
1998
Mus musculus, Mus sp.
Hidalgo, J; Belloso, E; Hernandez, J; Gasull, T; Molinero, A
Role of Glucocorticoids on Rat Brain Metallothionein-I and -III Response to Stress.
Stress
1
231-240
1997
Metazoa
Jalili, VP; Sidhu, SS; Kharbanda, OP
Status of dental caries and treatment needs in tribal children of Mandu (Central India).
J Pierre Fauchard Acad
7
7-15
1993
Homo sapiens
Lee, KF; Lau, KM; Ho, SM
Effects of cadmium on metallothionein-I and metallothionein-II mRNA expression in rat ventral, lateral, and dorsal prostatic lobes: quantification by competitive RT-PCR.
Toxicol Appl Pharmacol
154
20-7
1999
Rattus
Tota, MR; Smith, TS; Mao, C; MacNeil, T; Mosley, RT; Van der Ploeg, LH; Fong, TM
Molecular interaction of Agouti protein and Agouti-related protein with human melanocortin receptors.
Biochemistry
38
897-904
1999
Homo sapiens
Mullins, JE; Fredrickson, RA; Fuentealba, IC; Markham, RJ
Purification and partial characterization of a cadmium-binding protein from the liver of rainbow trout (Onchorynchus mykiss).
Can J Vet Res
63
225-9
1999
Chondrichthyes, Mus sp.
Bossolasco, M; Lebel, M; Lemieux, N; Mes-Masson, AM
The human TDE gene homologue: localization to 20q13.1-13.3 and variable expression in human tumor cell lines and tissue.
Mol Carcinog
26
189-200
1999
Mus musculus, Polyomavirus sp.
Carrasco, J; Giralt, M; Molinero, A; Penkowa, M; Moos, T; Hidalgo, J
Metallothionein (MT)-III: generation of polyclonal antibodies, comparison with MT-I+II in the freeze lesioned rat brain and in a bioassay with astrocytes, and analysis of Alzheimer's disease brains.
J Neurotrauma
16
1115-29
1999
Rattus
Lee, KF; Lau, KM; Ho, SM
Generation and characterization of hammerhead ribozymes targeting rodent metallothionein-I and -II ribonucleic acid.
Toxicol Appl Pharmacol
161
294-301
1999
Mus musculus, Rattus
Ren, HW; Itoh, N; Kanekiyo, M; Tominaga, S; Kohroki, J; Hwang, GS; Nakanishi, T; Muto, N; Tanaka, K
Two metallothioneins in the fresh-water fish, crucian carp (Carassius cuvieri): cDNA cloning and assignment of their expression isoforms.
Biol Pharm Bull
23
145-8
2000
Carassius carassius, vertebrata
Gong, YH; Elliott, JL
Metallothionein expression is altered in a transgenic murine model of familial amyotrophic lateral sclerosis.
Exp Neurol
162
27-36
2000
Mus musculus
Takano, H; Satoh, M; Shimada, A; Sagai, M; Yoshikawa, T; Tohyama, C
Cytoprotection by metallothionein against gastroduodenal mucosal injury caused by ethanol in mice.
Lab Invest
80
371-7
2000
Mus sp.
Carrasco, J; Penkowa, M; Hadberg, H; Molinero, A; Hidalgo, J
Enhanced seizures and hippocampal neurodegeneration following kainic acid-induced seizures in metallothionein-I + II-deficient mice.
Eur J Neurosci
12
2311-22
2000
Mus sp.
Chen, AS; Metzger, JM; Trumbauer, ME; Guan, XM; Yu, H; Frazier, EG; Marsh, DJ; Forrest, MJ; Gopal-Truter, S; Fisher, J; Camacho, RE; Strack, AM; Mellin, TN; MacIntyre, DE; Chen, HY; Van der Ploeg, LH
Role of the melanocortin-4 receptor in metabolic rate and food intake in mice.
Transgenic Res
9
145-54
2000
Mus sp.
Ono, SI; Cai, L; Koropatnick, J; Cherian, MG
Radiation exposure does not alter metallothionein III isoform expression in mouse brain.
Biol Trace Elem Res
74
23-30
2000
Mus sp.
Aoyama, Y; Kato, C; Sakakibara, S
Expression of metallothionein in the liver and kidney of rats is influenced by excess dietary histidine.
Comp Biochem Physiol C Toxicol Pharmacol
128
339-47
2001
Rattus
Sogawa, CA; Sogawa, N; Yamamoto, T; Oda, N; Inoue, T; Onodera, K; Furuta, H
Localization of metallothionein (MT) and expression of MT isoforms induced by cadmium in rat dental pulp.
Jpn J Pharmacol
86
65-72
2001
Rattus
Kuzniak, E; Skl&z shtsls;odowska, M
Ascorbate, glutathione and related enzymes in chloroplasts of tomato leaves infected by Botrytis cinerea.
Plant Sci
160
723-731
2001
Solanum lycopersicum, Botrytis cinerea
Fornai, F; Gesi, M; Saviozzi, M; Lenzi, P; Piaggi, S; Ferrucci, M; Casini, A
Immunohistochemical evidence and ultrastructural compartmentalization of a new antioxidant enzyme in the rat substantia nigra.
J Neurocytol
30
97-105
2001
Compacta, Electron, Rattus
Scudiero, R; Carginale, V; Capasso, C; Riggio, M; Filosa, S; Parisi, E
Structural and functional analysis of metal regulatory elements in the promoter region of genes encoding metallothionein isoforms in the Antarctic fish Chionodraco hamatus (icefish).
Gene
274
199-208
2001
Chionodraco hamatus
Hajdu, I; Obal, F; Fang, J; Krueger, JM; Rollo, CD
Sleep of transgenic mice producing excess rat growth hormone.
Am J Physiol Regul Integr Comp Physiol
282
R70-6
2002
Mus musculus, Rattus
Sasaki, K; Kitaguchi, Y; Koga, K; Narita, R; Fukuda, T; Aoyagi, Y
Dehydroascorbic acid reduction in several tissues and cultured hepatocytes of the chicken.
Biosci Biotechnol Biochem
65
2288-90
2001
Gallus gallus
Tschöp, M; Statnick, MA; Suter, TM; Heiman, ML
GH-releasing peptide-2 increases fat mass in mice lacking NPY: indication for a crucial mediating role of hypothalamic agouti-related protein.
Endocrinology
143
558-68
2002
Mus sp.
Zhang, J; Peng, WD; Hui, HX; Jin, M; Wang, DN; Wang, CJ; Qian, HW
Inducible Expression of bcl-2 Antisense RNA Promotes Apoptosis of Human Gastric Cancer Cell Line.
Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai)
31
279-283
1999
Homo sapiens
Kindblom, J; Dillner, K; Ling, C; Törnell, J; Wennbo, H
Progressive prostate hyperplasia in adult prolactin transgenic mice is not dependent on elevated serum androgen levels.
Prostate
53
24-33
2002
Mus musculus, Rattus
Savva, D; Garcia-Aljaro, C; Lawes, KP; Swiergosz-Kowalewska, R
Characterisation of DNA probes for the analysis of metallothionein gene expression in the bank vole (Clethrionomys glareolus).
Environ Int
28
139-46
2002
Myodes glareolus, Rodentia, Cricetulus griseus, Mus musculus, Rattus
Fodor, J; Gullner, G; Adam, AL; Barna, B; Komives, T; Kiraly, Z
Local and Systemic Responses of Antioxidants to Tobacco Mosaic Virus Infection and to Salicylic Acid in Tobacco (Role in Systemic Acquired Resistance).
Plant Physiol
114
1443-1451
1997
Nicotiana tabacum, tobacco mosaic virus
Luwe, M; Takahama, U; Heber, U
Role of Ascorbate in Detoxifying Ozone in the Apoplast of Spinach (Spinacia oleracea L.) Leaves.
Plant Physiol
101
969-976
1993
Spinacia oleracea
Mock, S; Shen, X; Tamvakopoulos, C
Determination of melanotan-II in rat plasma by liquid chromatography/tandem mass spectrometry: determination of pharmacokinetic parameters in rat following intravenous administration.
Rapid Commun Mass Spectrom
16
2142-7
2002
Rattus
Raposinho, PD; White, RB; Aubert, ML
The melanocortin agonist Melanotan-II reduces the orexigenic and adipogenic effects of neuropeptide Y (NPY) but does not affect the NPY-driven suppressive effects on the gonadotropic and somatotropic axes in the male rat.
J Neuroendocrinol
15
173-81
2003
Rattus
Zeng, X; Jin, T; Zhou, Y; Nordberg, GF
Changes of serum sex hormone levels and MT mRNA expression in rats orally exposed to cadmium.
Toxicology
186
109-18
2003
Rattus
Tadesse, A; Taye, E; Sandoval, F; Shannon, EJ
Thalidomide does not modify the ability of cells in leprosy patients to incorporate [3H]-thymidine when incubated with M. leprae antigens.
Lepr Rev
74
206-14
2003
Homo sapiens, Mycobacterium leprae
Fernando, MR; Satake, M; Monnier, VM; Lou, MF
Thioltranferase mediated ascorbate recycling in human lens epithelial cells.
Invest Ophthalmol Vis Sci
45
230-7
2004
Homo sapiens
Zeng, X; Jin, T; Zhou, Y
[Effects of oral cadmium exposure on expression of metallothionein-I and metallothionein-II mRNA in rat prostate]
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
20
323-6
2002
Rattus
Wang, WH; Li, LF; Zhang, BX; Lu, XY
Metallothionein-null mice exhibit reduced tolerance to ultraviolet B injury in vivo.
Clin Exp Dermatol
29
57-61
2004
Mus sp.
Jovanović-Galović, A; Blagojević, DP; Grubor-Lajsić, G; Worland, R; Spasić, MB
Role of antioxidant defense during different stages of preadult life cycle in European corn borer (Ostrinia nubilalis, Hubn.): Diapause and metamorphosis.
Arch Insect Biochem Physiol
55
79-89
2004
Ostrinia nubilalis, Lepidoptera
Sun, H; Greeley, DN; Chu, XJ; Cheung, A; Danho, W; Swistok, J; Wang, Y; Zhao, C; Chen, L; Fry, DC
A predictive pharmacophore model of human melanocortin-4 receptor as derived from the solution structures of cyclic peptides.
Bioorg Med Chem
12
2671-7
2004
Homo sapiens
Sappl, PG; Oñate-Sánchez, L; Singh, KB; Millar, AH
Proteomic analysis of glutathione S -transferases of Arabidopsis thaliana reveals differential salicylic acid-induced expression of the plant-specific phi and tau classes.
Plant Mol Biol
54
205-19
2004
Theta
Chen, L; Wu, W; Dentchev, T; Wong, R; Dunaief, JL
Increased metallothionein in light damaged mouse retinas.
Exp Eye Res
79
287-93
2004
Mus musculus
Liu, H; Zhu, Z; Lü, G
[Effect of low temperature stress on chilling tolerance and protective system against active oxygen of grafted watermelon]
Ying Yong Sheng Tai Xue Bao
15
659-62
2004
Citrullus lanatus subsp. vulgaris
Schmitt-Wrede, HP; Koewius, H; Tschuschke, S; Greven, H; Wunderlich, F
Genomic organization of the cadmium-inducible tandem repeat 25-kDa metallothionein of the oligochaete worm Enchytraeus buchholzi.
Biochim Biophys Acta
1680
24-33
2004
Mus musculus
Jiang, Y; Kang, YJ
Metallothionein gene therapy for chemical-induced liver fibrosis in mice.
Mol Ther
10
1130-9
2004
Mus sp., Homo sapiens
Liao, YH; Wang, CH; Tseng, CY; Chen, HL; Lin, LL; Chen, W
Compositional and conformational analysis of yam proteins by near infrared fourier transform Raman spectroscopy.
J Agric Food Chem
52
8190-6
2004
Dioscorea alata
Oliver, JR; Mara, TW; Cherian, MG
Impaired hepatic regeneration in metallothionein-I/II knockout mice after partial hepatectomy.
Exp Biol Med (Maywood)
230
61-7
2005
Mus sp.
Kim, EH; Kim, TS; Sun, W; Kim, DS; Chung, HS; Kim, DK; Park, SH
Differential regulation of metallothionein-I and metallothionein-II mRNA expression in the rat brain following traumatic brain injury.
Mol Cells
18
326-31
2004
Rattus
Kameo, S; Nakai, K; Kurokawa, N; Kanehisa, T; Naganuma, A; Satoh, H
Metal components analysis of metallothionein-III in the brain sections of metallothionein-I and metallothionein-II null mice exposed to mercury vapor with HPLC/ICP-MS.
Anal Bioanal Chem
381
1514-9
2005
Mus sp., Metazoa
Giuliano, F; Rössler, AS; Clément, P; Droupy, S; Alexandre, L; Bernabé, J
The use of telemetry technology to test the proerectile effect of melanotan-II (MT-II) in conscious rats.
Eur Urol
48
145-51; discussion 151-2
2005
Rattus, Metazoa
Oliver, JR; Jiang, S; Cherian, MG
Augmented hepatic injury followed by impaired regeneration in metallothionein-I/II knockout mice after treatment with thioacetamide.
Toxicol Appl Pharmacol
210
190-9
2006
Mus sp.
Stankovic, RK
Atrophy of large myelinated axons in metallothionein-I, II knockout mice.
Cell Mol Neurobiol
25
943-53
2005
Mus sp.
Pukacka, S; Ratajczak, E
Production and scavenging of reactive oxygen species in Fagus sylvatica seeds during storage at varied temperature and humidity.
J Plant Physiol
162
873-85
2005
Lethrinidae
Loney, KD; Uddin, RK; Singh, SM
Analysis of metallothionein brain gene expression in relation to ethanol preference in mice using cosegregation and gene knockouts.
Alcohol Clin Exp Res
30
15-25
2006
Mus sp.
Qian, QQ; Zai, WS; Zhu, ZJ; Yu, JQ
[Effects of Exogenous Silicon on Active Oxygen Scavenging Systems in Chloroplasts of Cucumber (Cucumis sativus L.) Seedlings under Salt Stress.]
Zhi Wu Sheng Li Yu Fen Zi Sheng Wu Xue Xue Bao
32
107-12
2006
Cucumis sativus
Spurgeon, DJ; Lofts, S; Hankard, PK; Toal, M; McLellan, D; Fishwick, S; Svendsen, C
Effect of pH on metal speciation and resulting metal uptake and toxicity for earthworms.
Environ Toxicol Chem
25
788-96
2006
Metaphire sieboldi
Dalton, DA; Russell, SA; Hanus, FJ; Pascoe, GA; Evans, HJ
Enzymatic reactions of ascorbate and glutathione that prevent peroxide damage in soybean root nodules.
Proc Natl Acad Sci U S A
83
3811-3815
1986
Glycine max
Jablonski, PP; Anderson, JW
Light-Dependent Reduction of Dehydroascorbate by Ruptured Pea Chloroplasts.
Plant Physiol
67
1239-1244
1981
Pisum sativum
Singh, VK; Hanson, J
Assessment of metallothionein and antibodies to metallothionein in normal and autistic children having exposure to vaccine-derived thimerosal.
Pediatr Allergy Immunol
17
291-6
2006
Homo sapiens
Wojtyla, Ł; Garnczarska, M; Zalewski, T; Bednarski, W; Ratajczak, L; Jurga, S
A comparative study of water distribution, free radical production and activation of antioxidative metabolism in germinating pea seeds.
J Plant Physiol
163
1207-20
2006
Pisum sativum, Electron
Zhang, GY; Kang, JG; Zhang, YG; Cheng, ZH; Wang, XW
[Gene cloning and expression analysis of a male sterility related gene BoDHAR from broccoli]
Sheng Wu Gong Cheng Xue Bao
22
751-6
2006
Arabidopsis, Brassica oleracea var. italica, Brassica oleracea var. capitata
Svendsen, C; Hankard, PK; Lister, LJ; Fishwick, SK; Jonker, MJ; Spurgeon, DJ
Effect of temperature and season on reproduction, neutral red retention and metallothionein responses of earthworms exposed to metals in field soils.
Environ Pollut
147
83-93
2007
Metaphire sieboldi
Wu, JP; Ma, BY; Ren, HW; Zhang, LP; Xiang, Y; Brown, MA
Characterization of metallothioneins (MT-I and MT-II) in the yak.
J Anim Sci
85
1357-62
2007
Bos grunniens, Mammalia
Elter, A; Hartel, A; Sieben, C; Hertel, B; Fischer-Schliebs, E; Lüttge, U; Moroni, A; Thiel, G
A plant homolog of animal chloride intracellular channels (CLICs) generates an ion conductance in heterologous systems.
J Biol Chem
282
8786-92
2007
Cricetulus griseus
Lee, YP; Kim, SH; Bang, JW; Lee, HS; Kwak, SS; Kwon, SY
Enhanced tolerance to oxidative stress in transgenic tobacco plants expressing three antioxidant enzymes in chloroplasts.
Plant Cell Rep
26
591-8
2007
Nicotiana tabacum
Jovanović-Galović, A; Blagojević, DP; Grubor-Lajsić, G; Worland, MR; Spasić, MB
Antioxidant defense in mitochondria during diapause and postdiapause development of European corn borer (Ostrinia nubilalis, Hubn.).
Arch Insect Biochem Physiol
64
111-9
2007
Felis catus, Lepidoptera, Ostrinia nubilalis
Ballet, S; Mayorov, AV; Cai, M; Tymecka, D; Chandler, KB; Palmer, ES; Rompaey, KV; Misicka, A; Tourwé, D; Hruby, VJ
Novel selective human melanocortin-3 receptor ligands: use of the 4-amino-1,2,4,5-tetrahydro-2-benzazepin-3-one (Aba) scaffold.
Bioorg Med Chem Lett
17
2492-8
2007
Homo sapiens
Swiergosz-Kowalewska, R; Bednarska, A; Callaghan, A
Expression of metallothionein genes I and II in bank vole Clethrionomys glareolus populations chronically exposed in situ to heavy metals.
Environ Sci Technol
41
1032-7
2007
Metazoa
Carias, CC; Novais, JM; Martins-Dias, S
Are Phragmites australis enzymes involved in the degradation of the textile azo dye acid orange 7?
Bioresour Technol
99
243-251
2008
Phragmites australis, plant, Felis catus
Grebić, D; Jakovac, H; Mrakovcić-Sutić, I; Tomac, J; Bulog, A; Micović, V; Radosević-Stasić, B
Short-term exposure of mice to gasoline vapor increases the metallothionein expression in the brain, lungs and kidney.
Histol Histopathol
22
593-601
2007
Mus sp.
Satoh, M
[Analysis of toxicity using metallothionein knockout mice]
Yakugaku Zasshi
127
709-17
2007
Mus sp.
Mani, D; Sharma, B; Kumar, C
Phytoaccumulation, interaction, toxicity and remediation of cadmium from Helianthus annuus L. (sunflower).
Bull Environ Contam Toxicol
79
71-9
2007
Helianthus
Strader, AD; Shi, H; Ogawa, R; Seeley, RJ; Reizes, O
The effects of the melanocortin agonist (MT-II) on subcutaneous and visceral adipose tissue in rodents.
J Pharmacol Exp Ther
322
1153-61
2007
Mus sp., Rattus
Albrecht, AL; Singh, RK; Somji, S; Sens, MA; Sens, DA; Garrett, SH
Basal and metal-induced expression of metallothionein isoform 1 and 2 genes in the RWPE-1 human prostate epithelial cell line.
J Appl Toxicol
28
283-93
2008
Homo sapiens
Hatziieremia, S; Kostomitsopoulos, N; Balafas, V; Tamvakopoulos, C
A liquid chromatographic/tandem mass spectroscopic method for quantification of the cyclic peptide melanotan-II. Plasma and brain tissue concentrations following administration in mice.
Rapid Commun Mass Spectrom
21
2431-8
2007
Mus musculus, Mus sp., Rattus, Rodentia
Lai, QX; Bao, ZY; Zhu, ZJ; Qian, QQ; Mao, BZ
Effects of osmotic stress on antioxidant enzymes activities in leaf discs of PSAG12-IPT modified Gerbera.
J Zhejiang Univ Sci B
8
458-64
2007
Felis catus, Gerbera, plant
Werner, J; Palace, V; Baron, C; Shiu, R; Yarmill, A
A real-time PCR method for the quantification of the two isoforms of metallothionein in Lake Trout (Salvelinus namaycush).
Arch Environ Contam Toxicol
54
84-91
2008
Salvelinus namaycush, Chondrichthyes, Salmonidae, Oncorhynchus mykiss
Wang, J; Ling, S; Usami, T; Murata, T; Narita, K; Higuchi, T
Effects of ghrelin, corticotrophin-releasing hormone, and melanotan-II on food intake in rats with paraventricular nucleus lesions.
Exp Clin Endocrinol Diabetes
115
669-73
2007
Rattus
Nagendra-Prasad, D; Sudhakar, N; Murugesan, K; Mohan, N
Pre-exposure of calli to ozone promotes tolerance of regenerated Lycopersicon esculentum cv. PKM1 plantlets against acute ozone stress.
J Plant Physiol
165
1288-99
2008
Solanum lycopersicum
Eddins, D; Petro, A; Pollard, N; Freedman, JH; Levin, ED
Mercury-induced cognitive impairment in metallothionein-1/2 null mice.
Neurotoxicol Teratol
30
88-95
0
Mus musculus
Kaklewski, K; Nowak, J; Ligocki, M
Effects of selenium content in green parts of plants on the amount of ATP and ascorbate-glutathione cycle enzyme activity at various growth stages of wheat and oilseed rape.
J Plant Physiol
165
1011-22
2008
Brassica napus, Triticum aestivum, plant
Buico, A; Cassino, C; Dondero, F; Vergani, L; Osella, D
Radical scavenging abilities of fish MT-A and mussel MT-10 metallothionein isoforms: An ESR study.
J Inorg Biochem
102
921-927
2008
Oryctolagus cuniculus
Gao, QH; Wang, XF; Shi, QH; Yang, FJ; Wei, M
[Effects of lanthanum on the plant growth and leaf anti-oxidative enzyme activities of cucumber seedlings under nitrate stress]
Ying Yong Sheng Tai Xue Bao
19
976-80
2008
plant, Felis catus
Jin, XF; Yang, XE; Islam, E; Liu, D; Mahmood, Q; Li, H; Li, J
Ultrastructural changes, zinc hyperaccumulation and its relation with antioxidants in two ecotypes of Sedum alfredii Hance.
Plant Physiol Biochem
46
997-1006
2008
Sedum alfredii
Ding, Y; Cheng, H; Song, S
Changes in extreme high-temperature tolerance and activities of antioxidant enzymes of sacred lotus seeds.
Sci China C Life Sci
51
842-53
2008
Felis catus, Lotus, Zea mays
Cui, X; Okayasu, R
Arsenic accumulation, elimination, and interaction with copper, zinc and manganese in liver and kidney of rats.
Food Chem Toxicol
46
3646-50
2008
Rattus
Wastney, ME; House, WA
Development of a compartmental model of zinc kinetics in mice.
J Nutr
138
2148-55
2008
Mus sp.
Benavente, F; Andón, B; Giménez, E; Olivieri, AC; Barbosa, J; Sanz-Nebot, V
A multiway approach for classification and characterization of rabbit liver apothioneins by CE-ESI-MS.
Electrophoresis
29
4355-67
2008
Oryctolagus cuniculus
Cheng, HY; Song, SQ
Possible Involvement of Reactive Oxygen Species Scavenging Enzymes in Desiccation Sensitivity of Antiaris toxicaria Seeds and Axes.
J Integr Plant Biol
50
1549-56
2008
Antiaris toxicaria, Felis catus
Rubio, MC; Bustos-Sanmamed, P; Clemente, MR; Becana, M
Effects of salt stress on the expression of antioxidant genes and proteins in the model legume Lotus japonicus.
New Phytol
2008
Lotus japonicus, plant
Rousseau-Gueutin, M; Gaston, A; Aïnouche, A; Aïnouche, ML; Olbricht, K; Staudt, G; Richard, L; Denoyes-Rothan, B
Tracking the evolutionary history of polyploidy in Fragaria L. (strawberry): new insights from phylogenetic analyses of low-copy nuclear genes.
Mol Phylogenet Evol
51
515-30
2009
Fragaria, Fragaria iturupensis, Ferula moschata, Fragariinae
Williams, PL; Ma, H; Glenn, TC; Jagoe, CH; Jones, KL
A TRANSGENIC STRAIN OF THE NEMATODE CAENORHABDITIS ELEGANS AS A BIOMONITOR FOR HEAVY METAL CONTAMINATION.
Environ Toxicol Chem
1
2009
Nematoda, Caenorhabditis elegans
Lin, PL; Lin, KW; Weng, CF; Lin, KC
Yam Storage Protein Dioscorins from Dioscorea alata and Dioscorea japonica Exhibit Distinct Immunomodulatory Activities in Mice.
J Agric Food Chem
2009
Dioscorea alata
Ishibashi, Y; Yamamoto, K; Tawaratsumida, T; Yuasa, T; Iwaya-Inoue, M
Hydrogen peroxide scavenging regulates germination ability during wheat (Triticum aestivum L.) seed maturation.
Plant Signal Behav
3
183-8
2008
Triticum aestivum, Felis catus
Jiang, GC; Hughes, S; Stürzenbaum, SR; Evje, L; Syversen, T; Aschner, M
Caenorhabditis elegans metallothioneins protect against toxicity induced by depleted uranium.
Toxicol Sci
111
345-54
2009
Nematoda
Wen, B; Wang, R; Cheng, H; Song, S
Cytological and physiological changes in orthodox maize embryos during cryopreservation.
Protoplasma
239
57-67
2010
Zea mays, Felis catus
Nakajima, K; Kodaira, T; Kato, M; Nakazato, K; Tokita, Y; Kikuchi, H; Sekine, H; Suzuki, K; Nagamine, T
Development of an enzyme-linked immunosorbent assay for metallothionein-I and -II in plasma of humans and experimental animals.
Clin Chim Acta
411
758-61
2010
Homo sapiens, Metazoa
Wang, Z; Xiao, Y; Chen, W; Tang, K; Zhang, L
Increased vitamin C content accompanied by an enhanced recycling pathway confers oxidative stress tolerance in Arabidopsis.
J Integr Plant Biol
52
400-9
2010
Arabidopsis, Arabidopsis thaliana, Metazoa, plant
Ni, H; Li, C; Feng, X; Cen, JN
Effects of Forced Running Exercise on Cognitive Function and Its Relation to Zinc Homeostasis-Related Gene Expression in Rat Hippocampus.
Biol Trace Elem Res
2010
Rattus, Hippocampus
Honda, A; Komuro, H; Shimada, A; Hasegawa, T; Seko, Y; Nagase, H; Hozumi, I; Inuzuka, T; Hara, H; Fujiwara, Y; Satoh, M
Attenuation of cadmium-induced testicular injury in metallothionein-III null mice.
Life Sci
87
545-50
2010
Mus sp.
Span, C; Bottega, S; Grilli, I; Lorenzi, R
Responses to desiccation injury in developing wheat embryos from naturally- and artificially-dried grains.
Plant Physiol Biochem
49
363-7
2011
Triticum aestivum
Raynaud, C; Lee, J; Sarabal, P; Croux, C; Meynial-Salles, I; Soucaille, P
Molecular Characterization of the glycerol oxidative pathway of Clostridium butyricum VPI 1718.
J Bacteriol
2011
Butea monosperma
Cheng, Z; Lan, T; Li, D; Yang, H; Zeng, Q
[Molecular characterizations of two dehydroascorbate reductases from Selaginella moellendorffii].
Sheng Wu Gong Cheng Xue Bao
27
76-84
2011
plant, Selaginella, Escherichia coli, Selaginella moellendorffii
Lunge, S; Biniwale, R; Labhsetwar, N; Rayalu, SS
User perception study for performance evaluation of domestic defluoridation techniques for its application in rural areas.
J Hazard Mater
191
325-32
2011
Areas
Sato, M; Apostolova, MD; Hamaya, M; Yamaki, J; Choo, KH; Michalska, AE; Kodama, N; Tohyama, C
Susceptibility of metallothionein-null mice to paraquat.
Environ Toxicol Pharmacol
1
221-5
1996
Mus musculus
Oofusa, K; Tooi, O; Kashiwagi, A; Kashiwagi, K; Kondo, Y; Obara, M; Yoshizato, K
Metal ion-responsive transgenic Xenopus laevis as an environmental monitoring animal.
Environ Toxicol Pharmacol
13
153-159
2003
Mus musculus
Del Buono, D; Ioli, G; Nasini, L; Proietti, P
A comparative study on the interference of two herbicides in wheat and italian ryegrass and on their antioxidant activities and detoxification rates.
J Agric Food Chem
59
12109-15
2011
Lolium multiflorum, Triticum aestivum
Oelze, ML; Vogel, MO; Alsharafa, K; Kahmann, U; Viehhauser, A; Maurino, VG; Dietz, KJ
Efficient acclimation of the chloroplast antioxidant defence of Arabidopsis thaliana leaves in response to a 10- or 100-fold light increment and the possible involvement of retrograde signals.
J Exp Bot
63
1297-313
2012
Arabidopsis thaliana
Semchuk, NM; Vasylyk, YV; Kubrak, OI; Lushchak, VI
Effect of sodium nitroprusside and S-nitrosoglutathione on pigment content and antioxidant system of tocopherol-deficient plants of Arabidopsis thaliana.
Ukr Biokhim Zh
83
69-79
0
plant, Arabidopsis thaliana
Arellano-Ruiz, S; Rios, C; Salgado-Ceballos, H; Mndez-Armenta, M; Del Valle-Mondragn, L; Nava-Ruiz, C; Altagracia-Martnez, M; Daz-Ruiz, A
Metallothionein-II improves motor function recovery and increases spared tissue after spinal cord injury in rats.
Neurosci Lett
2012
Rattus
Jin, H; Jin, F; Jin, JX; Xu, J; Tao, TT; Liu, J; Huang, HJ
Protective effects of Ganoderma lucidum spore on cadmium hepatotoxicity in mice.
Food Chem Toxicol
2012
Ganoderma lucidum
Jheng, YJ; Tsai, WY; Chen, KH; Lin, KW; Chyan, CL; Yang, CC; Lin, KC
Recombinant dioscorins of the yam storage protein expressed in Escherichia coli exhibit antioxidant and immunomodulatory activities.
Protein Expr Purif
85
77-85
2012
Escherichia coli, Dioscorea japonica, Dioscorea pseudojaponica
Tsai, WY; Jheng, YJ; Chen, KH; Lin, KW; Ho, YP; Yang, CC; Lin, KC
Molecular cloning, structural analysis and mass spectrometric identification of native dioscorins of various yam species.
J Sci Food Agric
2012
Dioscorea alata, Dioscorea japonica, Dugesia japonica, Dioscorea pseudojaponica
Kato, H; Takemoto, D; Kawakita, K
Proteomic analysis of S-nitrosylated proteins in potato plant.
Physiol Plant
2012
Solanum tuberosum, plant, Escherichia coli, Tuber
Rinne, P; Tikka, S; Mkel, S; Streng, T; Savontaus, E
Hemodynamic actions and mechanisms of systemically administered ?-MSH analogues in mice.
Peptides
2012
Mus sp.
Nakayama, SM; Ikenaka, Y; Hamada, K; Muzandu, K; Choongo, K; Yabe, J; Umemura, T; Ishizuka, M
Accumulation and biological effects of metals in wild rats in mining areas of Zambia.
Environ Monit Assess
2012
Rattus
Mercer, RE; Michaelson, SD; Chee, MJ; Atallah, TA; Wevrick, R; Colmers, WF
Magel2 is required for leptin-mediated depolarization of POMC neurons in the hypothalamic arcuate nucleus in mice.
PLoS Genet
9
e1003207
2013
Mus sp.
Huang, H; Song, S
Change in desiccation tolerance of maize embryos during development and germination at different water potential PEG-6000 in relation to oxidative process.
Plant Physiol Biochem
68
61-70
2013
Zea mays
Wang, H; Xu, R; You, L; Zhong, G
Characterization of Cu-tolerant bacteria and definition of their role in promotion of growth, Cu accumulation and reduction of Cu toxicity in Triticum aestivum L.
Ecotoxicol Environ Saf
94
1-7
2013
Bacillus, Bacteria, plant, Triticum aestivum
Sanahuja, G; Farr, G; Bassie, L; Zhu, C; Christou, P; Capell, T
Ascorbic acid synthesis and metabolism in maize are subject to complex and genotype-dependent feedback regulation during endosperm development.
Biotechnol J
8
1221-1230
2013
Zea mays, Oryza sativa, Electron
Wang, H; Wang, T; You, L; Zhong, G; Shi, G
Effects of vanadate supply on plant growth, Cu accumulation, and antioxidant capacities in Triticum aestivum L.
Environ Geochem Health
35
585-92
2013
Triticum aestivum
Cuil, Z; Zhu, Z
Hormonal replacement therapy in fish:human growth hormone gene function in hypophysectomized carp.
Fish Physiol Biochem
12
161-9
1993
Homo sapiens, Mus musculus
Talukdar, D; Talukdar, T
Coordinated response of sulfate transport, cysteine biosynthesis, and glutathione-mediated antioxidant defense in lentil (Lens culinaris Medik.) genotypes exposed to arsenic.
Protoplasma
2013
Penicillium simile
Wang, L; Liu, X; Liang, M; Tan, F; Liang, W; Chen, Y; Lin, Y; Huang, L; Xing, J; Chen, W
Proteomic analysis of salt-responsive proteins in the leaves of mangrove Kandelia candel during short-term stress.
PLoS One
9
e83141
2014
Kandelia candel
D'Hooghe, P; Dubousset, L; Gallardo, K; Kopriva, S; Avice, JC; Trouverie, J
Evidence for proteomic and metabolic adaptations associated to alterations of seed yield and quality in sulphur-limited Brassica napus L.
Mol Cell Proteomics
2014
plant
Diaz-Ruiz, A; Vacio-Adame, P; Monroy-Noyola, A; Mndez-Armenta, M; Ortiz-Plata, A; Montes, S; Rios, C
Metallothionein-II Inhibits Lipid Peroxidation and Improves Functional Recovery after Transient Brain Ischemia and Reperfusion in Rats.
Oxid Med Cell Longev
2014
436429
2014
Rattus
Wei, RC; Zhao, H; Ma, XJ; Mi, K; Mo, CM; Pan, LM; Bai, LH; Tang, Q
[Extraction of total RNA and cloning of sgDHAR gene from Siraitia grosvenorii].
Yao Xue Xue Bao
49
115-23
2014
Siraitia, Cucumis sativus, Siraitia grosvenorii
Li, J; Xu, RF; Qin, RY; Ma, H; Li, H; Zhang, YP; Li, L; Wei, PC; Yang, JB
Isolation and functional characterization of a novel rice constitutive promoter.
Plant Cell Rep
33
1651-60
2014
Oryza sativa
Lyubenova, L; Bipuah, H; Belford, E; Michalke, B; Winkler, B; Schrder, P
Comparative study on the impact of copper sulphate and copper nitrate on the detoxification mechanisms in Typha latifolia.
Environ Sci Pollut Res Int
22
657-66
2015
Typha latifolia, Typha
Singh, VP; Kumar, J; Singh, S; Prasad, SM
Dimethoate modifies enhanced UV-B effects on growth, photosynthesis and oxidative stress in mung bean (Vigna radiata L.) seedlings: implication of salicylic acid.
Pestic Biochem Physiol
116
13-23
2014
Vigna radiata, Vigna radiata var. radiata
Tam, NN; Zhang, X; Xiao, H; Song, D; Levin, L; Meller, J; Ho, SM
Increased susceptibility of estrogen-induced bladder outlet obstruction in a novel mouse model.
Lab Invest
2015
Mus musculus
Jancs, Z; Bdi, N; Borsos, B; Fekete, ; Hermesz, E
Gut region-specific accumulation of reactive oxygen species leads to regionally distinct activation of antioxidant and apoptotic marker molecules in rats with STZ-induced diabetes.
Int J Biochem Cell Biol
62
125-31
2015
Metazoa
Gtz-Rsch, C; Sieper, T; Fekete, A; Schmitt-Kopplin, P; Hartmann, A; Schrder, P
Influence of bacterial N-acyl-homoserine lactones on growth parameters, pigments, antioxidative capacities and the xenobiotic phase II detoxification enzymes in barley and yam bean.
Front Plant Sci
6
205
2015
Hordeum vulgare, plant
Singh, A; Prasad, SM
A lucrative technique to reduce Ni toxicity in Raphanus sativus plant by phosphate amendment: Special reference to plant metabolism.
Ecotoxicol Environ Saf
119
81-9
2015
Felis catus
Kanwar, MK; Poonam, ; Pal, S; Bhardwaj, R
Involvement of Asada-Halliwell Pathway During Phytoremediation of Chromium (VI) in Brassica juncea L. Plants.
Int J Phytoremediation
17
1237-43
2015
Felis catus
Matthus, E; Wu, LB; Ueda, Y; Hller, S; Becker, M; Frei, M
Loci, genes, and mechanisms associated with tolerance to ferrous iron toxicity in rice (Oryza sativa L.).
Theor Appl Genet
128
2085-98
2015
Oryza sativa
AbdElgawad, H; Zinta, G; Hegab, MM; Pandey, R; Asard, H; Abuelsoud, W
High Salinity Induces Different Oxidative Stress and Antioxidant Responses in Maize Seedlings Organs.
Front Plant Sci
7
276
2016
Zea mays, plant
Ren, J; Sun, LN; Zhang, QY; Song, XS
Drought Tolerance Is Correlated with the Activity of Antioxidant Enzymes in Cerasus humilis Seedlings.
Biomed Res Int
2016
9851095
2016
Prunus humilis, Areas, Calibrachoa humilis
Drga, V; Plack, CJ; Yasin, I
Frequency Tuning of the Efferent Effect on Cochlear Gain in Humans.
Adv Exp Med Biol
894
477-84
2016
Homo sapiens
Everhardt Queen, A; Moerdyk-Schauwecker, M; McKee, LM; Leamy, LJ; Huet, YM
Differential Expression of Inflammatory Cytokines and Stress Genes in Male and Female Mice in Response to a Lipopolysaccharide Challenge.
PLoS One
11
e0152289
2016
Mus sp., Escherichia coli
Bashri, G; Prasad, SM
Exogenous IAA differentially affects growth, oxidative stress and antioxidants system in Cd stressed Trigonella foenum-graecum L. seedlings: Toxicity alleviation by up-regulation of ascorbate-glutathione cycle.
Ecotoxicol Environ Saf
132
329-38
2016
Felis catus
Czgny, G; Le Martret, B; Pvkovics, D; Dix, PJ; Hideg,
Elevated ROS-scavenging enzymes contribute to acclimation to UV-B exposure in transplastomic tobacco plants, reducing the role of plastid peroxidases.
J Plant Physiol
201
95-100
2016
Nicotiana tabacum
Hashem, A; Abd Allah, EF; Alqarawi, AA; Al-Huqail, AA; Shah, MA
Induction of Osmoregulation and Modulation of Salt Stress in Acacia gerrardii Benth. by Arbuscular Mycorrhizal Fungi and Bacillus subtilis (BERA 71).
Biomed Res Int
2016
6294098
2016
Felis catus, plant
Li, H; Lu, YF; Chen, H; Liu, J
Dysregulation of metallothionein and circadian genes in human hepatocellular carcinoma.
Chronobiol Int
34
192-202
2017
Homo sapiens
Liang, D; Zhu, T; Ni, Z; Lin, L; Tang, Y; Wang, Z; Wang, X; Wang, J; Lv, X; Xia, H
Ascorbic acid metabolism during sweet cherry (Prunus avium) fruit development.
PLoS One
12
e0172818
2017
Prunus avium
Niu, K; Ma, X; Liang, G; Ma, H; Jia, Z; Liu, W; Yu, Q
5-Aminolevulinic acid modulates antioxidant defense systems and mitigates drought-induced damage in Kentucky bluegrass seedlings.
Protoplasma
2017
Felis catus
Amin, OM; Heckmann, RA; Zargar, UR
DESCRIPTION OF A NEW QUADRIGYRID ACANTHOCEPHALAN FROM KASHMIR, WITH NOTES ON METAL ANALYSIS AND HISTOPATHOLOGY, AND A KEY TO SPECIES OF THE SUBGENUS ACANTHOSENTIS FROM THE INDIAN SUBCONTINENT.
J Parasitol
2017
Neoechinorhynchus, Tor tor, Bangana diplostoma
Lund, B; Nielsen, TG; Lind, M
Cartilage status in FAI patients - results from the Danish Hip Arthroscopy Registry (DHAR).
SICOT J
3
44
2017
Homo sapiens
Mygind-Klavsen, B; Lund, B; Nielsen, TG; Maagaard, N; Kraemer, O; Hlmich, P; Winge, S; Lind, M
Danish Hip Arthroscopy Registry: predictors of outcome in patients with femoroacetabular impingement (FAI).
Knee Surg Sports Traumatol Arthrosc
2018
Homo sapiens
Saini, S; Kaur, N; Pati, PK
Reactive oxygen species dynamics in roots of salt sensitive and salt tolerant cultivars of rice.
Anal Biochem
550
99-108
2018
Felis catus
Kumar, S; Chauhan, A; Kumar, A; Kumar, S; Gupta, A; Roy, S; Kumari, SC
Dental fluorosis and associated risk factors in early adolescents in India.
Int J Adolesc Med Health
2018
Homo sapiens
Cheng, B; Li, Z; Liang, L; Cao, Y; Zeng, W; Zhang, X; Ma, X; Huang, L; Nie, G; Liu, W; Peng, Y
The ?-Aminobutyric Acid (GABA) Alleviates Salt Stress Damage during Seeds Germination of White Clover Associated with Na?/K? Transportation, Dehydrins Accumulation, and Stress-Related Genes Expression in White Clover.
Int J Mol Sci
19
2018
Felis catus
Wu, Z; Xu, S; Shi, H; Zhao, P; Liu, X; Li, F; Deng, T; Du, R; Wang, X; Wang, F
Comparison of foliar silicon and selenium on cadmium absorption, compartmentation, translocation and the antioxidant system in Chinese flowering cabbage.
Ecotoxicol Environ Saf
166
157-164
2018
plant
Khanna, K; Jamwal, VL; Kohli, SK; Gandhi, SG; Ohri, P; Bhardwaj, R; Abd Allah, EF; Hashem, A; Ahmad, P
Plant growth promoting rhizobacteria induced Cd tolerance in Lycopersicon esculentum through altered antioxidative defense expression.
Chemosphere
217
463-474
2019
Felis catus
Minakova, E; Lang, J; Medel-Matus, JS; Gould, GG; Reynolds, A; Shin, D; Mazarati, A; Sankar, R
Melanotan-II reverses autistic features in a maternal immune activation mouse model of autism.
PLoS One
14
e0210389
2019
Mus musculus, Mus sp.
Singh, J; Singh, V; Vineeth, TV; Kumar, P; Kumar, N; Sharma, PC
Differential response of Indian mustard (Brassica juncea L., Czern and Coss) under salinity: photosynthetic traits and gene expression.
Physiol Mol Biol Plants
25
71-83
2019
Brassica juncea
Wang, H; Chen, Y; Hu, W; Snider, JL; Zhou, Z
Short-term soil-waterlogging contributes to cotton cross tolerance to chronic elevated temperature by regulating ROS metabolism in the subtending leaf.
Plant Physiol Biochem
139
333-341
2019
Gossypium hirsutum, Felis catus, plant
Awasthi, JP; Saha, B; Panigrahi, J; Yanase, E; Koyama, H; Panda, SK
Redox balance, metabolic fingerprint and physiological characterization in contrasting North East Indian rice for Aluminum stress tolerance.
Sci Rep
9
8681
2019
Felis catus
Qu, Q; Zhang, Z; Li, Y; Zhou, Z; Ye, Y; Lu, T; Sun, L; Qian, H
Comparative molecular and metabolic responses of wheat seedlings (Triticum aestivum L.) to the imazethapyr enantiomers S-IM and R-IM.
Sci Total Environ
692
723-731
2019
Felis catus
Khanna, K; Sharma, A; Ohri, P; Bhardwaj, R; Abd Allah, EF; Hashem, A; Ahmad, P
Impact of Plant Growth Promoting Rhizobacteria in the Orchestration of Lycopersicon esculentum Mill. Resistance to Plant Parasitic Nematodes: A Metabolomic Approach to Evaluate Defense Responses Under Field Conditions.
Biomolecules
9
2019
Felis catus, Nematoda
Shekhar, S; Rustagi, A; Kumar, D; Yusuf, MA; Sarin, NB; Lawrence, K
Groundnut AhcAPX conferred abiotic stress tolerance in transgenic banana through modulation of the ascorbate-glutathione pathway.
Physiol Mol Biol Plants
25
1349-1366
2019
Musa acuminata, Felis catus
Wu, Z; Jiang, Q; Yan, T; Zhang, X; Xu, S; Shi, H; Deng, TH; Li, F; Du, Y; Du, R; Hu, C; Wang, X; Wang, F
Ammonium nutrition mitigates cadmium toxicity in rice (Oryza sativa L.) through improving antioxidase system and the glutathione-ascorbate cycle efficiency.
Ecotoxicol Environ Saf
189
110010
2020
Oryza sativa
Bali, S; Kaur, P; Jamwal, VL; Gandhi, SG; Sharma, A; Ohri, P; Bhardwaj, R; Ali, MA; Ahmad, P
Seed Priming with Jasmonic Acid Counteracts Root Knot Nematode Infection in Tomato by Modulating the Activity and Expression of Antioxidative Enzymes.
Biomolecules
10
2020
Felis catus
Lewis, KEA; Bennett, W; Blizzard, CL; West, AK; Chung, RS; Chuah, MI
The influence of metallothionein treatment and treadmill running exercise on disease onset and survival in SOD1G93A amyotrophic lateral sclerosis mice.
Eur J Neurosci
2020
Mus sp.
Xue, HY; Zhao, Y; Liu, ZH; Wang, XW; Zhang, JW; Peng, X; Tanokura, M; Xue, YL
Recovery of Yam Soluble Protein from Yam Starch Processing Wastewater.
Sci Rep
10
5384
2020
Dioscorea alata
Muoz, PT; Rodrguez-Rojas, F; Celis-Pl, PSM; Mndez, L; Pinto, D; Pardo, D; Moenne, F; Snchez-Lizaso, JL; Sez, CA
Physiological and metabolic responses to hypersalinity reveal interpopulation tolerance in the green macroalga Ulva compressa with different pollution histories.
Aquat Toxicol
225
105552
2020
Ulva compressa
Semwal, VK; Khanna-Chopra, R
Enhanced oxidative stress, damage and inadequate antioxidant defense contributes towards insufficient recovery in water deficit stress and heat stress combination compared to either stresses alone in Chenopodium album (Bathua).
Physiol Mol Biol Plants
26
1331-1339
2020
Chenopodium album, Felis catus
Obidiegwu, JE; Lyons, JB; Chilaka, CA
The Dioscorea Genus (Yam)-An Appraisal of Nutritional and Therapeutic Potentials.
Foods
9
2020
Dioscorea alata
Ma, ZJ; Li, GZ; Chen, SM; Han, JL; Hanif, Q
Rich maternal and paternal genetic diversity and divergent lineage composition in wild yak (Bos mutus).
Anim Biotechnol
1-5
2021
Bos mutus
Ma, ZJ; Li, GZ; Chen, SM; Han, JL; Hanif, Q
Rich maternal and paternal genetic diversity and divergent lineage composition in wild yak (Bos mutus).
Anim Biotechnol
1-4
2021
Bos mutus
Bashri, G; Singh, S; Prasad, SM; Ansari, MJ; Usmani, S; Alfarraj, S; Alharbi, SA; Brestic, M
Kinetin mitigates Cd-induced damagesto growth, photosynthesis and PS II photochemistry of Trigonella seedlings by up-regulating ascorbate-glutathione cycle.
PLoS One
16
e0249230
2021
Trigonella
Karar, YFM; Blend, CK; Dronen, NO; Adel, A
Towards resolving the problematic status of the digenean genus Astiotrema Looss, 1900: An updated concept and revision of species composition for Astiotrema (sensu stricto).
Zootaxa
4991
36-72
2021
Astiotrema, Astiotrema reniferum, Astiotrema odhneri
Hong, TI; Hwang, KS; Choi, TI; Kleinau, G; Scheerer, P; Bang, JK; Jung, SH; Kim, CH
Zebrafish Bioassay for Screening Therapeutic Candidates Based on Melanotrophic Activity.
Int J Mol Sci
22
2021
Mus musculus
Alharazi, WZ; McGowan, A; Rose, P; Jethwa, PH
Could consumption of yam (Dioscorea) or its extract be beneficial in controlling glycaemia - A Systematic Review.
Br J Nutr
1-32
2021
Dioscorea alata, Dioscorea polystachya
Tseng TY;Ou JF;Wang CY
Role of the AscorbateGlutathione Cycle in Paraquat Tolerance of Rice
Weed Science
61
361-373
2013
Oryza sativa
Zou L;Li H;Ouyang B;Zhang J;Ye Z
Cloning and mapping of genes involved in tomato ascorbic acid biosynthesis and metabolism.
Plant science : an international journal of experimental plant biology
170
120-127
2006
Solanum lycopersicum
Zhu Z;Wei G;Li J;Qian Q;Yu J
Silicon alleviates salt stress and increases antioxidant enzymes activity in leaves of salt-stressed cucumber (Cucumis sativus L.).
Plant science : an international journal of experimental plant biology
167
527-533
2004
Cucumis sativus, Felis catus, plant
Reeves PhilipG
Copper metabolism in metallothionein-null mice fed a high-zinc diet
The Journal of nutritional biochemistry
9
598-601
1998
Mus musculus
Wells, WW; Xu, DP; Yang, YF; Rocque, PA
Mammalian thioltransferase (glutaredoxin) and protein disulfide isomerase have dehydroascorbate reductase activity.
J Biol Chem
265
15361-4
1990
Homo sapiens, Sus scrofa, Bos taurus
Dias, RG; Sampaio, SC; Sant'Anna, MB; Cunha, FQ; Gutirrez, JM; Lomonte, B; Cury, Y; Picolo, G
Articular inflammation induced by an enzymatically-inactive Lys49 phospholipase A
J Venom Anim Toxins Incl Trop Dis
23
18
2017
Metazoa
Piaggi, S; Marchi, E; Carnicelli, V; Zucchi, R; Griese, M; Hector, A; Sorio, C; Pompella, A; Corti, A
Airways glutathione S-transferase omega-1 and its A140D polymorphism are associated with severity of inflammation and respiratory dysfunction in cystic fibrosis.
J Cyst Fibros
2021
Homo sapiens, clinical samples
Davis, MO; Hata, DJ; Johnson, SA; Jones, DE; Harmata, MA; Evans, ML; Walker, JC; Smith, DS
Cloning, sequence, and expression of a blood group B active recombinant alpha-D-galactosidase from pinto bean (Phaseolus vulgaris).
Biochem Mol Biol Int
42
453-67
1997
Phaseolus vulgaris
Kaya, C; Ashraf, M; Alyemeni, MN; Ahmad, P
The role of nitrate reductase in brassinosteroid-induced endogenous nitric oxide generation to improve cadmium stress tolerance of pepper plants by upregulating the ascorbate-glutathione cycle.
Ecotoxicol Environ Saf
196
110483
2020
plant
Wörgötter, E; Wagner, G; Vasák, M; Kägi, JH; Wüthrich, K
Sequence-specific 1H-NMR assignments in rat-liver metallothionein-2.
Eur J Biochem
167
457-66
1987
Rattus
Wagner, G; Neuhaus, D; Wörgötter, E; Vasák, M; Kägi, JH; Wüthrich, K
Sequence-specific 1H-NMR assignments in rabbit-liver metallothionein-2.
Eur J Biochem
157
275-89
1986
Oryctolagus cuniculus
Stahl, RL; Liebes, LF; Silber, R
A reappraisal of leukocyte dehydroascorbate reductase.
Biochim Biophys Acta
839
119-21
1985
Homo sapiens, Spinacia oleracea
Morell, S; Follmann, H; De Tullio, M; Häberlein, I
Dehydroascorbate and dehydroascorbate reductase are phantom indicators of oxidative stress in plants.
FEBS Lett
414
567-70
1997
plant
Bednarek, MA; Silva, MV; Arison, B; MacNeil, T; Kalyani, RN; Huang, RR; Weinberg, DH
Structure-function studies on the cyclic peptide MT-II, lactam derivative of alpha-melanotropin.
Peptides
20
401-9
1999
Homo sapiens
Yao, CP; Allen, JW; Mutkus, LA; Xu, SB; Tan, KH; Aschner, M
Foreign metallothionein-I expression by transient transfection in MT-I and MT-II null astrocytes confers increased protection against acute methylmercury cytotoxicity.
Brain Res
855
32-8
2000
Mus musculus, Mus sp.
Jung, CH; Washburn, MP; Wells, WW
Ebselen has dehydroascorbate reductase and thioltransferase-like activities.
Biochem Biophys Res Commun
291
550-3
2002
Bos taurus
Wessells, H; Hruby, VJ; Hackett, J; Han, G; Balse-Srinivasan, P; Vanderah, TW
MT-II induces penile erection via brain and spinal mechanisms.
Ann N Y Acad Sci
994
90-5
2003
Rattus, Poromitra oscitans
Seeley, RJ; Burklow, ML; Wilmer, KA; Matthews, CC; Reizes, O; McOsker, CC; Trokhan, DP; Gross, MC; Sheldon, RJ
The effect of the melanocortin agonist, MT-II, on the defended level of body adiposity.
Endocrinology
146
3732-8
2005
Rattus
Shi, R; McDonald, L; Cygler, M; Ekiel, I
Coiled-Coil Helix Rotation Selects Repressing or Activating State of Transcriptional Regulator DhaR.
Structure
22
478-87
2014
Butea monosperma
Menon, D; Innes, A; Oakley, AJ; Dahlstrom, JE; Jensen, LM; Brstle, A; Tummala, P; Rooke, M; Casarotto, MG; Baell, JB; Nguyen, N; Xie, Y; Cuellar, M; Strasser, J; Dahlin, JL; Walters, MA; Burgio, G; O'Neill, LAJ; Board, PG
GSTO1-1 plays a pro-inflammatory role in models of inflammation, colitis and obesity.
Sci Rep
7
17832
2017
Bacteria, Mus sp.
Fernando, N; Wooff, Y; Aggio-Bruce, R; Chu-Tan, JA; Jiao, H; Dietrich, C; Rutar, M; Rooke, M; Menon, D; Eells, JT; Valter, K; Board, PG; Provis, J; Natoli, R
Photoreceptor Survival Is Regulated by GSTO1-1 in the Degenerating Retina.
Invest Ophthalmol Vis Sci
59
4362-4374
2018
Mus sp.
Huang, X; Deng, J; Xu, T; Xin, W; Zhang, Y; Ruan, X
Downregulation of metallothionein-2 contributes to oxaliplatin-induced neuropathic pain.
J Neuroinflammation
18
91
2021
Rattus
Bortolatto, CF; Chagas, PM; Wilhelm, EA; Zeni, G; Nogueira, CW
2,2'-dithienyl diselenide, an organoselenium compound, elicits antioxidant action and inhibits monoamine oxidase activity in vitro.
J Enzyme Inhib Med Chem
2012
Rattus
May, JM; Mendiratta, S; Hill, KE; Burk, RF
Reduction of dehydroascorbate to ascorbate by the selenoenzyme thioredoxin reductase.
J Biol Chem
272
22607-10
1997
Rattus
Aykaç-Toker, G; Bulgurcuoğlu, S; Koçak-Toker, N
Effect of peroxynitrite on glutaredoxin.
Hum Exp Toxicol
20
373-6
2001
Rattus
Tanida, M; Yamamoto, N; Shibamoto, T; Rahmouni, K
Involvement of Hypothalamic AMP-Activated Protein Kinase in Leptin-Induced Sympathetic Nerve Activation.
PLoS One
8
e56660
2013
Rattus
Cawley, KC; Akita, CG; Walsh, DA
Expression of a cDNA for the catalytic subunit of skeletal-muscle phosphorylase kinase in transfected 3T3 cells.
Biochem J
263
223-9
1989
Mus musculus
Dulhunty, A; Gage, P; Curtis, S; Chelvanayagam, G; Board, P
The glutathione transferase structural family includes a nuclear chloride channel and a ryanodine receptor calcium release channel modulator.
J Biol Chem
276
3319-23
2001
Homo sapiens
Board, PG; Coggan, M; Cappello, J; Zhou, H; Oakley, AJ; Anders, MW
S-(4-Nitrophenacyl)glutathione is a specific substrate for glutathione transferase omega 1-1.
Anal Biochem
374
25-30
2008
Homo sapiens, Mus musculus
Paiva, L; Marcos, R; Creus, A; Coggan, M; Oakley, AJ; Board, PG
Polymorphism of glutathione transferase Omega 1 in a population exposed to a high environmental arsenic burden.
Pharmacogenet Genomics
18
1-10
2008
Homo sapiens
Hughes, MM; Hooftman, A; Angiari, S; Tummala, P; Zaslona, Z; Runtsch, MC; McGettrick, AF; Sutton, CE; Diskin, C; Rooke, M; Takahashi, S; Sundararaj, S; Casarotto, MG; Dahlstrom, JE; Palsson-McDermott, EM; Corr, SC; Mills, KHG; Preston, RJS; Neamati, N; Xie, Y; Baell, JB; Board, PG; O'Neill, LAJ
Glutathione Transferase Omega-1 Regulates NLRP3 Inflammasome Activation through NEK7 Deglutathionylation.
Cell Rep
29
151-161.e5
2019
Mus sp.
Boulanger, Y; Armitage, IM; Miklossy, KA; Winge, DR
113Cd NMR study of a metallothionein fragment. Evidence for a two-domain structure.
J Biol Chem
257
13717-9
1982
Homo sapiens
Eidizadeh, A; Khajehalichalehshtari, M; Freyer, D; Trendelenburg, G
Assessment of the Therapeutic Potential of Metallothionein-II Application in Focal Cerebral Ischemia In Vitro and In Vivo.
PLoS One
10
e0144035
2015
Metazoa, Mus sp.
Lu, Y; Wang, HR; Li, H; Cui, HR; Feng, YG; Wang, XY
A chloroplast membrane protein LTO1/AtVKOR involving in redox regulation and ROS homeostasis.
Plant Cell Rep
32
1427-40
2013
Lethrinidae
Wang, L; Bao, S; Liu, X; Wang, F; Zhang, J; Dang, P; Wang, F; Li, B; Lin, Y
Low-dose exposure to black carbon significantly increase lung injury of cadmium by promoting cellular apoptosis.
Ecotoxicol Environ Saf
224
112703
2021
Homo sapiens
Winkler, BS; Orselli, SM; Rex, TS
The redox couple between glutathione and ascorbic acid: a chemical and physiological perspective.
Free Radic Biol Med
17
333-49
1994
animal
Frei, M; Wissuwa, M; Pariasca-Tanaka, J; Chen, CP; Sdekum, KH; Kohno, Y
Leaf ascorbic acid level - Is it really important for ozone tolerance in rice?
Plant Physiol Biochem
2012
insertion sequences, Oryza sativa
Wells, WW; Xu, DP
Dehydroascorbate reduction.
J Bioenerg Biomembr
26
369-77
1994
animal, Rodentia, Metazoa
Meyer, EB; Wells, WW
Thioltransferase overexpression increases resistance of MCF-7 cells to adriamycin.
Free Radic Biol Med
26
770-6
1999
Homo sapiens
Sharma, A; Yuan, H; Kumar, V; Ramakrishnan, M; Kohli, SK; Kaur, R; Thukral, AK; Bhardwaj, R; Zheng, B
Castasterone attenuates insecticide induced phytotoxicity in mustard.
Ecotoxicol Environ Saf
179
50-61
2019
Felis catus
Zhao, Y; Chen, L; Gao, S; Toselli, P; Stone, P; Li, W
The critical role of the cellular thiol homeostasis in cadmium perturbation of the lung extracellular matrix.
Toxicology
267
60-9
2010
Waelput, W; Verhee, A; Broekaert, D; Eyckerman, S; Vandekerckhove, J; Beattie, JH; Tavernier, J
Identification and expression analysis of leptin-regulated immediate early response and late target genes.
Biochem J
348 Pt 1
55-61
2000
Mus sp.
Hasanuzzaman, M; Hossain, MA; Fujita, M
Selenium-Induced Up-Regulation of the Antioxidant Defense and Methylglyoxal Detoxification System Reduces Salinity-Induced Damage in Rapeseed Seedlings.
Biol Trace Elem Res
2011
Felis catus
Hasanuzzaman, M; Hossain, MA; Fujita, M
Exogenous Selenium Pretreatment Protects Rapeseed Seedlings from Cadmium-Induced Oxidative Stress by Upregulating Antioxidant Defense and Methylglyoxal Detoxification Systems.
Biol Trace Elem Res
2012
Felis catus
Yu, X; Wu, Z; Fenselau, C
Covalent sequestration of melphalan by metallothionein and selective alkylation of cysteines.
Biochemistry
34
3377-85
1995
Homo sapiens, Oryctolagus cuniculus
Zuliani, JP; Gutiérrez, JM; Casais e Silva, LL; Coccuzzo Sampaio, S; Lomonte, B; Pereira Teixeira, Cde F
Activation of cellular functions in macrophages by venom secretory Asp-49 and Lys-49 phospholipases A(2).
Toxicon
46
523-32
2005
Mus musculus
Mercer, JF; Wake, SA
An analysis of the rate of metallothionein mRNA poly(A)-shortening using RNA blot hybridization.
Nucleic Acids Res
13
7929-43
1985
Mus musculus, Rattus
Sugiyama, K; Arai, K; Aikawa, A; Miyagi, M; Ohara, T; Hasegawa, A; Muramatsu, M; Hirayama, N; Tajima, E; Kawamura, T; Ogihara, H; Hadano, T; Nakano, H
Reversibility from delayed hyperacute rejection in ABO-incompatible renal transplantation: histopathological findings of renal allograft biopsy.
Transplant Proc
37
701-4
2005
Homo sapiens
Shadiack, AM; Sharma, SD; Earle, DC; Spana, C; Hallam, TJ
Melanocortins in the treatment of male and female sexual dysfunction.
Curr Top Med Chem
7
1137-44
2007
Homo sapiens
Poelarends, GJ; Kulakov, LA; Larkin, MJ; van Hylckama Vlieg, JE; Janssen, DB
Roles of horizontal gene transfer and gene integration in evolution of 1,3-dichloropropene- and 1,2-dibromoethane-degradative pathways.
J Bacteriol
182
2191-9
2000
Pseudomonas sp.
Li, Z; Peng, Y; Huang, B
Alteration of Transcripts of Stress-Protective Genes and Transcriptional Factors by ?-Aminobutyric Acid (GABA) Associated with Improved Heat and Drought Tolerance in Creeping Bentgrass (Agrostis stolonifera).
Int J Mol Sci
19
2018
Felis catus
Lu, YF; Wu, Q; Liang, SX; Miao, JW; Shi, JS; Liu, J
Evaluation of hepatotoxicity potential of cinnabar-containing An-Gong-Niu-Huang Wan, a patent traditional Chinese medicine.
Regul Toxicol Pharmacol
2011
Mus sp.
Perveen, H; Chattopadhyay, S; Maity, M; Dash, M; Islam, SS
Involvement of proinflammatory cytokines and metallothionein in the repairing of arsenic-mediated uterine tissue damage by curcumin.
J Basic Clin Physiol Pharmacol
30
2019
Rattus
del Río, LA; Corpas, FJ; Sandalio, LM; Palma, JM; Gómez, M; Barroso, JB
Reactive oxygen species, antioxidant systems and nitric oxide in peroxisomes.
J Exp Bot
53
1255-72
2002
plant
Whitbread, AK; Masoumi, A; Tetlow, N; Schmuck, E; Coggan, M; Board, PG
Characterization of the omega class of glutathione transferases.
Methods Enzymol
401
78-99
2005
Homo sapiens, Rattus
Iturbe-Ormaetxe, I; Matamoros, MA; Rubio, MC; Dalton, DA; Becana, M
The antioxidants of legume nodule mitochondria.
Mol Plant Microbe Interact
14
1189-96
2001
Electron, Rhizobium leguminosarum bv. phaseoli, plant
Gill, SS; Tuteja, N
Reactive oxygen species and antioxidant machinery in abiotic stress tolerance in crop plants.
Plant Physiol Biochem
48
909-30
2010
Felis catus, plant
Pietronigro, DD; Hovsepian, M; Demopoulos, HB; Flamm, ES
Reductive metabolism of ascorbic acid in the central nervous system.
Brain Res
333
161-4
1985
Felis catus, Rattus
Lester, GE; Hodges, DM; Meyer, RD; Munro, KD
Pre-extraction preparation (fresh, frozen, freeze-dried, or acetone powdered) and long-term storage of fruit and vegetable tissues: effects on antioxidant enzyme activity.
J Agric Food Chem
52
2167-73
2004
Cucumis melo var. inodorus, Spinacia oleracea
de Pinto, MC; De Gara, L
Changes in the ascorbate metabolism of apoplastic and symplastic spaces are associated with cell differentiation.
J Exp Bot
55
2559-69
2004
Pisum sativum
Anjum, NA; Gill, SS; Gill, R; Hasanuzzaman, M; Duarte, AC; Pereira, E; Ahmad, I; Tuteja, R; Tuteja, N
Metal/metalloid stress tolerance in plants: role of ascorbate, its redox couple, and associated enzymes.
Protoplasma
2014
Electron, plant
Talaat, NB
Effective microorganisms enhance the scavenging capacity of the ascorbate-glutathione cycle in common bean (Phaseolus vulgaris L.) plants grown in salty soils.
Plant Physiol Biochem
80
136-43
2014
Phaseolus vulgaris, plant
Liu, F; Wang, L; Gu, L; Zhao, W; Su, H; Cheng, X
Higher transcription levels in ascorbic acid biosynthetic and recycling genes were associated with higher ascorbic acid accumulation in blueberry.
Food Chem
188
399-405
2015
Vaccinium corymbosum
Yang, W; Wang, HY; Yu, KY; Lou, H; Ji, GS; Ruan, YN
[Effects of elevated Cd, Zn and their combined effects on antioxidant system of tobacco].
Ying Yong Sheng Tai Xue Bao
28
1948-1954
2017
Nicotiana tabacum
Ulhassan, Z; Gill, RA; Huang, H; Ali, S; Mwamba, TM; Ali, B; Huang, Q; Hamid, Y; Khan, AR; Wang, J; Zhou, W
Selenium mitigates the chromium toxicity in Brassicca napus L. by ameliorating nutrients uptake, amino acids metabolism and antioxidant defense system.
Plant Physiol Biochem
145
142-152
2019
Felis catus
Kaya, C
Salicylic acid-induced hydrogen sulphide improves lead stress tolerance in pepper plants by upraising the ascorbate-glutathione cycle.
Physiol Plant
2020
plant
Pukacka, S; Ratajczak, E
Ascorbate and glutathione metabolism during development and desiccation of orthodox and recalcitrant seeds of the genus Acer.
Funct Plant Biol
34
601-613
2007
Acer platanoides
Rajput, VD; Harish, ; Singh, RK; Verma, KK; Sharma, L; Quiroz-Figueroa, FR; Meena, M; Gour, VS; Minkina, T; Sushkova, S; Mandzhieva, S
Recent Developments in Enzymatic Antioxidant Defence Mechanism in Plants with Special Reference to Abiotic Stress.
Biology (Basel)
10
2021
plant
Schwanz, P; Polle, A
Antioxidative systems, pigment and protein contents in leaves of adult mediterranean oak species (Quercus pubescens and Q. ilex) with lifetime exposure to elevated CO2.
New Phytol
140
411-423
1998
Quercus pubescens
Dorigan de Matos Furlanetto, AL; Kaziuk, FD; Martinez, GR; Donatti, L; Merlin Rocha, ME; Dos Santos, ALW; Floh, EIS; Cadena, SMSC
Mitochondrial bioenergetics and enzymatic antioxidant defense differ in Paran pine cell lines with contrasting embryogenic potential.
Free Radic Res
55
255-266
2021
Araucaria angustifolia, Coniferophyta
Schwartz, RA
66th annual meeting, american academy of dermatology, san antonio, Texas, 2008.
Acta Dermatovenerol Croat
16
46
2008
Gabriella, Corinna
Rose, RC; Bode, AM
Tissue-mediated regeneration of ascorbic acid: is the process enzymatic?
Enzyme
46
196-203
1992
animal, Metazoa
Dai, Z; Takahashi, SI; Van Wyk, JJ; D'Ercole, AJ
Creation of an autocrine model of insulin-like growth factor-I action in transfected FRTL-5 cells.
Endocrinology
130
3175-83
1992
Mus musculus
Thompson, JA; Sutherland, AE
A comparison of methods for sample clean-up prior to quantification of metal-binding proteins.
Comp Biochem Physiol B
102
769-72
1992
Oryctolagus cuniculus
Qi, M; Stasenko, LJ; DeFranco, DB
Recycling and desensitization of glucocorticoid receptors in v-mos transformed cells depend on the ability of nuclear receptors to modulate gene expression.
Mol Endocrinol
4
455-64
1990
Rattus
Brar, AK; Coleman, TA; Kopchick, JJ; Frohman, LA
Expression of a cytomegalovirus-human growth hormone-releasing hormone precursor fusion gene in transfected GH3 cells.
Mol Cell Endocrinol
71
105-15
1990
Homo sapiens, Mus musculus
Klaassen, CD; Lehman-McKeeman, LD
Regulation of the isoforms of metallothionein.
Biol Trace Elem Res
21
119-29
0
Rattus
Thornalley, PJ; Vasák, M
Possible role for metallothionein in protection against radiation-induced oxidative stress. Kinetics and mechanism of its reaction with superoxide and hydroxyl radicals.
Biochim Biophys Acta
827
36-44
1985
Bos taurus, Oryctolagus cuniculus
Ding, X; Bill, E; Good, M; Trautwein, AX; Vasák, M
Mössbauer studies on the metal-thiolate cluster formation in Fe(II)-metallothionein.
Eur J Biochem
171
711-4
1988
Oryctolagus cuniculus
Rose, RC; Choi, JL; Koch, MJ
Intestinal transport and metabolism of oxidized ascorbic acid (dehydroascorbic acid).
Am J Physiol
254
G824-8
1988
Cavia porcellus
Lehman, LD; Klaassen, CD
Separation and quantitation of metallothioneins by high-performance liquid chromatography coupled with atomic absorption spectrophotometry.
Anal Biochem
153
305-14
1986
Rattus
Vasák, M; Kägi, JH; Holmquist, B; Vallee, BL
Spectral studies of cobalt (II)- and Nickel (II)-metallothionein.
Biochemistry
20
6659-64
1981
Oryctolagus cuniculus
Vasák, M; Kägi, JH
Metal thiolate clusters in cobalt(II)-metallothionein.
Proc Natl Acad Sci U S A
78
6709-13
1981
Oryctolagus cuniculus
Mitsumori, F; Tohyama, C
Proton nuclear magnetic resonance studies of mammalian metallothioneins.
J Biochem (Tokyo)
96
533-43
1984
Homo sapiens, Oryctolagus cuniculus, Rattus
Boulanger, Y; Goodman, CM; Forte, CP; Fesik, SW; Armitage, IM
Model for mammalian metallothionein structure.
Proc Natl Acad Sci U S A
80
1501-5
1983
Mus musculus
Neale, GA; Mao, S; Parham, DM; Murti, KG; Goorha, RM
Expression of the proto-oncogene rhombotin-2 is identical to the acute phase response protein metallothionein, suggesting multiple functions.
Cell Growth Differ
6
587-96
1995
Homo sapiens, Mus sp.
Maret, W
Metallothionein/disulfide interactions, oxidative stress, and the mobilization of cellular zinc.
Neurochem Int
27
111-7
1995
Oryctolagus cuniculus
Quaife, CJ; Findley, SD; Erickson, JC; Froelick, GJ; Kelly, EJ; Zambrowicz, BP; Palmiter, RD
Induction of a new metallothionein isoform (MT-IV) occurs during differentiation of stratified squamous epithelia.
Biochemistry
33
7250-9
1994
insertion sequences
Masters, BA; Kelly, EJ; Quaife, CJ; Brinster, RL; Palmiter, RD
Targeted disruption of metallothionein I and II genes increases sensitivity to cadmium.
Proc Natl Acad Sci U S A
91
584-8
1994
Mus musculus, Mus sp.
Wells, WW; Yang, Y; Deits, TL; Gan, ZR
Thioltransferases.
Adv Enzymol Relat Areas Mol Biol
66
149-201
1993
Pisum sativum
Xiang, J; Koropatnick, J; Qi, Y; Luo, X; Moyana, T; Li, K; Chen, Y
Production of a bifunctional hybrid molecule B72.3/metallothionein-1 by protein engineering.
Immunology
78
574-81
1993
Mus musculus
Ohta, H
[Role of trace elements on metallothionein gene expression]
Nippon Rinsho
54
40-5
1996
Homo sapiens
Dorr, RT; Lines, R; Levine, N; Brooks, C; Xiang, L; Hruby, VJ; Hadley, ME
Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study.
Life Sci
58
1777-84
1996
Homo sapiens, Poromitra oscitans
McCall, MN; Kuchel, MG; Basten, A
Evaluation of antisense inhibition in a B cell model.
Biochem Mol Biol Int
42
45-56
1997
Mus musculus
Hoff, CM; Cusick, JL; Masse, EM; Jackman, RW; Nagy, JA; Shockley, TR
Modulation of transgene expression in mesothelial cells by activation of an inducible promoter.
Nephrol Dial Transplant
13
1420-9
1998
Homo sapiens, Mus musculus, Rattus
Ghoshal, K; Wang, Y; Sheridan, JF; Jacob, ST
Metallothionein induction in response to restraint stress. Transcriptional control, adaptation to stress, and role of glucocorticoid.
J Biol Chem
273
27904-10
1998
Mus musculus, Metazoa
Haynes, WG; Morgan, DA; Djalali, A; Sivitz, WI; Mark, AL
Interactions between the melanocortin system and leptin in control of sympathetic nerve traffic.
Hypertension
33
542-7
1999
bat
Kumar, TR; Palapattu, G; Wang, P; Woodruff, TK; Boime, I; Byrne, MC; Matzuk, MM
Transgenic models to study gonadotropin function: the role of follicle-stimulating hormone in gonadal growth and tumorigenesis.
Mol Endocrinol
13
851-65
1999
Homo sapiens, Mus musculus
Levadoux, M; Mahon, C; Beattie, JH; Wallace, HM; Hesketh, JE
Nuclear import of metallothionein requires its mRNA to be associated with the perinuclear cytoskeleton.
J Biol Chem
274
34961-6
1999
Cricetulus griseus
Bhattacharya, D; Bhattacharya, R; Dhar, TK
A novel signal amplification technology for ELISA based on catalyzed reporter deposition. Demonstration of its applicability for measuring aflatoxin B(1).
J Immunol Methods
230
71-86
1999
Electron
Huang, RR; Singh, G; Van der Ploeg, LH; Fong, TM
Species-dependent pharmacological properties of the melanocortin-5 receptor.
J Recept Signal Transduct Res
20
47-59
2000
Homo sapiens
Gehrig, PM; You, C; Dallinger, R; Gruber, C; Brouwer, M; Kägi, JH; Hunziker, PE
Electrospray ionization mass spectrometry of zinc, cadmium, and copper metallothioneins: evidence for metal-binding cooperativity.
Protein Sci
9
395-402
2000
Caenorhabditis elegans
Liu, Y; Wang, H; Zhao, J; Ma, J; Wei, L; Wu, S; Xie, T; Shen, F; Trojan, J; Habib, N; Anthony, DD; Wu, M; Guo, Y
Enhancement of immunogenicity of tumor cells by cotransfection with genes encoding antisense insulin-like growth factor-1 and B7.1 molecules.
Cancer Gene Ther
7
456-65
2000
Mus musculus, Metazoa
Board, PG; Coggan, M; Chelvanayagam, G; Easteal, S; Jermiin, LS; Schulte, GK; Danley, DE; Hoth, LR; Griffor, MC; Kamath, AV; Rosner, MH; Chrunyk, BA; Perregaux, DE; Gabel, CA; Geoghegan, KF; Pandit, J
Identification, characterization, and crystal structure of the Omega class glutathione transferases.
J Biol Chem
275
24798-806
2000
Homo sapiens
Aravindakumar, CT; Ceulemans, J; De Ley, M
Steric effect and effect of metal coordination on the reactivity of nitric oxide with cysteine-containing proteins under anaerobic conditions.
Biophys Chem
85
1-6
2000
Bos taurus
Klaverkamp, JF; Wautier, K; Baron, CL
A modified mercury saturation assay for measuring metallothionein.
Aquatic Toxicol
50
13-25
2000
Salvelinus namaycush, Oryctolagus cuniculus
Berweger, CD; Thiel, W; van Gunsteren, WF
Molecular-dynamics simulation of the beta domain of metallothionein with a semi-empirical treatment of the metal core.
Proteins
41
299-315
2000
Rattus
Sogawa, CA; Asanuma, M; Sogawa, N; Miyazaki, I; Nakanishi, T; Furuta, H; Ogawa, N
Localization, regulation, and function of metallothionein-III/growth inhibitory factor in the brain.
Acta Med Okayama
55
1-9
2001
Mammalia
Wang, Y; Oberley, LW; Murhammer, DW
Antioxidant defense systems of two lipidopteran insect cell lines.
Free Radic Biol Med
30
1254-62
2001
Spodoptera frugiperda, Trichoplusia ni
Theocharis, S; Karkantaris, C; Philipides, T; Agapitos, E; Gika, A; Margeli, A; Kittas, C; Koutselinis, A
Expression of metallothionein in lung carcinoma: correlation with histological type and grade.
Histopathology
40
143-51
2002
Homo sapiens
Wolters, FL; de Vocht, TF; Klis, SF; Hamers, FP; Smoorenburg, GF
Co-treatment with melanotan-II, a potent melanocortin, does not protect against cisplatin ototoxicity.
Hear Res
172
110-7
2002
Cavia
Puttaparthi, K; Gitomer, WL; Krishnan, U; Son, M; Rajendran, B; Elliott, JL
Disease progression in a transgenic model of familial amyotrophic lateral sclerosis is dependent on both neuronal and non-neuronal zinc binding proteins.
J Neurosci
22
8790-6
2002
Mus musculus, Mus sp.
Wilhelmsen, TW; Olsvik, PA; Hansen, BH; Andersen, RA
Evidence for oligomerization of metallothioneins in their functional state.
J Chromatogr A
979
249-54
2002
Equus caballus, Oryctolagus cuniculus
Chen, Z; Young, TE; Ling, J; Chang, SC; Gallie, DR
Increasing vitamin C content of plants through enhanced ascorbate recycling.
Proc Natl Acad Sci U S A
100
3525-30
2003
Nicotiana tabacum, Triticum aestivum, Zea mays, Homo sapiens, Metazoa
Ebadi, M; Ramana Kumari, MV; Hiramatsu, M; Hao, R; Pfeiffer, RF; Rojas, P
Metallothionein, neurotrophins and selegiline in providing neuroprotection in Parkinson's disease.
Restor Neurol Neurosci
12
103-11
1998
Electron
Samama, P; Rumennik, L; Grippo, JF
The melanocortin receptor MCR4 controls fat consumption.
Regul Pept
113
85-8
2003
Mus sp.
Ejnik, JW; Muñoz, A; DeRose, E; Shaw, CF; Petering, DH
Structural consequences of metallothionein dimerization: solution structure of the isolated Cd4-alpha-domain and comparison with the holoprotein dimer.
Biochemistry
42
8403-10
2003
Oryctolagus cuniculus
Baraboĭ, VA; Petrina, LG
[Metallothioneins: the structure and mechanisms of action]
Ukr Biokhim Zh
75
28-36
0
animal
Mitropoulos, D; Kyroudi-Voulgari, A; Theocharis, S; Serafetinides, E; Moraitis, E; Zervas, A; Kittas, C
Prognostic significance of metallothionein expression in renal cell carcinoma.
World J Surg Oncol
3
5
2005
Homo sapiens, Mus musculus
Kobayashi, K; Shida, R; Hasegawa, T; Satoh, M; Seko, Y; Tohyama, C; Kuroda, J; Shibata, N; Imura, N; Himeno, S
Induction of hepatic metallothionein by trivalent cerium: role of interleukin 6.
Biol Pharm Bull
28
1859-63
2005
Mus sp.
Aschner, M; West, AK
The role of MT in neurological disorders.
J Alzheimers Dis
8
139-45; discussion 209-15
2005
Hippocampus
Erni, B; Siebold, C; Christen, S; Srinivas, A; Oberholzer, A; Baumann, U
Small substrate, big surprise: fold, function and phylogeny of dihydroxyacetone kinases.
Cell Mol Life Sci
63
890-900
2006
Butea monosperma, Escherichia coli
Wolff, NA; Abouhamed, M; Verroust, PJ; Thévenod, F
Megalin-dependent internalization of cadmium-metallothionein and cytotoxicity in cultured renal proximal tubule cells.
J Pharmacol Exp Ther
318
782-91
2006
Alexa
Chu, MM; Guo, ZQ; Muto, N; Itoh, N; Tanaka, K; Ren, HW
Development of ELISA for metallothionein-II allows determination of heavy metal pollution of fresh water.
Front Biosci
11
2113-22
2006
Cyprinus carpio, Indicator, Carassius carassius
Wiseman, DA; Wells, SM; Wilham, J; Hubbard, M; Welker, JE; Black, SM
Endothelial response to stress from exogenous Zn2+ resembles that of NO-mediated nitrosative stress, and is protected by MT-1 overexpression.
Am J Physiol Cell Physiol
291
C555-68
2006
Chelator
Zhou, M; Nakatani, E; Gronenberg, LS; Tokimoto, T; Wirth, MJ; Hruby, VJ; Roberts, A; Lynch, RM; Ghosh, I
Peptide-labeled quantum dots for imaging GPCRs in whole cells and as single molecules.
Bioconjug Chem
18
323-32
0
Homo sapiens
King, SH; Mayorov, AV; Balse-Srinivasan, P; Hruby, VJ; Vanderah, TW; Wessells, H
Melanocortin receptors, melanotropic peptides and penile erection.
Curr Top Med Chem
7
1098-1106
2007
Homo sapiens
Raposinho, PD; Xavier, C; Correia, JD; Falcão, S; Gomes, P; Santos, I
Melanoma targeting with alpha-melanocyte stimulating hormone analogs labeled with fac-[(99m)Tc(CO) (3)] (+): effect of cyclization on tumor-seeking properties.
J Biol Inorg Chem
13
449-59
2008
Mus sp.
Stewart, FJ; Young, CR; Cavanaugh, CM
Lateral symbiont acquisition in a maternally transmitted chemosynthetic clam endosymbiosis.
Mol Biol Evol
25
673-87
2008
Vesicomya sp. mt-II
Sakharov, DV; Lim, C
Force fields including charge transfer and local polarization effects: Application to proteins containing multi/heavy metal ions.
J Comput Chem
30
191-202
2009
Rattus
Ohtsuji, M; Katsuoka, F; Kobayashi, A; Aburatani, H; Hayes, JD; Yamamoto, M
Nrf1 and Nrf2 play distinct roles in activation of antioxidant response element-dependent genes.
J Biol Chem
283
33554-62
2008
Mus sp.
Garnczarska, M; Bednarski, W; Jancelewicz, M
Ability of lupine seeds to germinate and to tolerate desiccation as related to changes in free radical level and antioxidants in freshly harvested seeds.
Plant Physiol Biochem
47
56-62
2009
Electron, Lupinus luteus, plant
Masuzaki, H; Tanaka, T; Ebihara, K; Hosoda, K; Nakao, K
[Energy homeostasis regulated by an adipocyte-derived hormone--mechanism of leptin resistance and role of hypothalamic melanocortin signaling]
Nippon Rinsho
67
287-96
2009
Mus sp.
Masuzaki, H; Tanaka, T; Ebihara, K; Hosoda, K; Nakao, K
Hypothalamic melanocortin signaling and leptin resistance-Perspective of therapeutic application for obesity-diabetes syndrome.
Peptides
2009
Mus musculus, Mus sp.
Toda, C; Shiuchi, T; Lee, S; Yamato-Esaki, M; Fujino, Y; Suzuki, A; Okamoto, S; Minokoshi, Y
Distinct effects of leptin and a melanocortin receptor agonist injected into medial hypothalamic nuclei on glucose uptake in peripheral tissues.
Diabetes
2009
Mus sp., bat
Thyssen, JP; Jakobsen, SS; Engkilde, K; Johansen, JD; Søballe, K; Menné, T
The association between metal allergy, total hip arthroplasty, and revision.
Acta Orthop
80
646-52
2009
Homo sapiens
Milnerowicz, H; Bizoń, A
Determination of metallothionein in biological fluids using enzyme-linked immunoassay with commercial antibody.
Acta Biochim Pol
57
99-104
2010
Homo sapiens, Mus musculus
Board, PG
The omega-class glutathione transferases: structure, function, and genetics.
Drug Metab Rev
43
226-35
2011
Homo sapiens
Tsui, L; Ramagli, L; Gao, C; Pham, C; Pandita, T; Arlinghaus, R; Singh, B
The biological effects of antisense mos expression in fibroblasts.
Int J Oncol
11
1171-8
1997
Mus musculus
Dixon, DP; Edwards, R
Glutathione transferases.
Arabidopsis Book
8
e0131
2010
Arabidopsis, Theta
Hernandez, M; Fernandez-Garcia, N; Garcia-Garma, J; Rubio-Asensio, JS; Rubio, F; Olmos, E
Potassium starvation induces oxidative stress inSolanum lycopersicumL. roots.
J Plant Physiol
169
1366-74
2012
Felis catus
Fujiwara, Y; Satoh, M
Protective Role of Metallothionein in Chemical and Radiation Carcinogenesis.
Curr Pharm Biotechnol
2013
Mus sp.
Chekhun, VF; Lozovska, YV; Burlaka, AP; Lukyanova, NY; Todor, IN; Naleskina, LA
Peculiarities of antioxidant system and iron metabolism in organism during development of tumor resistance to cisplatin.
Exp Oncol
36
196-201
2014
Rattus
Manikandan, M; Kannan, V; Mahalingam, K; Vimala, A; Chun, S
Phytoremediation potential of chromium-containing tannery effluent-contaminated soil by native Indian timber-yielding tree species.
Prep Biochem Biotechnol
46
100-8
2016
Acacia auriculiformis, Albizia lebbeck, Apinagia richardiana, Azadirachta indica, Dalbergia, plant, Thespesia populnea
Shinkai, Y; Kimura, T; Itagaki, A; Yamamoto, C; Taguchi, K; Yamamoto, M; Kumagai, Y; Kaji, T
Partial contribution of the Keap1-Nrf2 system to cadmium-mediated metallothionein expression in vascular endothelial cells.
Toxicol Appl Pharmacol
295
37-46
2016
Bos taurus
Boshoff, HI
Caught between two proteins: a mycobacterial inhibitor challenges the mold.
Mol Microbiol
103
2-6
2017
Mycobacterium tuberculosis
Rahantaniaina, MS; Li, S; Chatel-Innocenti, G; Tuzet, A; Issakidis-Bourguet, E; Mhamdi, A; Noctor, G
Cytosolic and chloroplastic DHARs cooperate in oxidative stress-driven activation of the salicylic acid pathway.
Plant Physiol
2017
Arabidopsis
Bertuzzi, S; Pellegrini, E; Candotto Carniel, F; Incerti, G; Lorenzini, G; Nali, C; Tretiach, M
Ozone and desiccation tolerance in chlorolichens are intimately connected: a case study based on two species with different ecology.
Environ Sci Pollut Res Int
2017
Parmotrema perlatum
Tokumoto, M; Lee, JY; Shimada, A; Tohyama, C; Satoh, M
Glutathione has a more important role than metallothionein-I/II against inorganic mercury-induced acute renal toxicity.
J Toxicol Sci
43
275-280
2018
Mus sp.
Mygind-Klavsen, B; Kraemer, O; Hlmich, P; Lund, B
An Updated Description of More Than 5,000 Procedures from the Danish Hip Arthroscopy Registry.
J Bone Joint Surg Am
2020
Homo sapiens
Poulsen, E; Lund, B; Roos, EM
The Danish Hip Arthroscopy Registry: Registration Completeness and Patient Characteristics Between Responders and Non-Responders.
Clin Epidemiol
12
825-833
2020
Homo sapiens
Ali, A; Muhammad, N; Hussain, S; Jamil, MI; Uddin, A; Aziz, T; Tufail, MK; Guo, Y; Wei, T; Rasool, G; Fan, Z; Guo, L
Kinetic and Thermal Study of Ethylene and Propylene Homo Polymerization Catalyzed by ansa-Zirconocene Activated with Alkylaluminum/Borate: Effects of Alkylaluminum on Polymerization Kinetics and Polymer Structure.
Polymers (Basel)
13
2021
Camellia sinensis
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