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Contains FAD. The enzyme, which is found only in halobacteria, maintains the concentration of gamma-glutamylcysteine, the major low molecular weight thiol in halobacteria. Not identical with EC 22.214.171.124 (glutathione-disulfide reductase) or EC 126.96.36.199 (CoA-disulfide reductase).
enzyme is annotated as mercuric reductase. Enzyme that is expressed in Escherichia coli and refolded from inclusion bodies has robust bis-gamma-glutamylcystine reductase activity but no mercuric reductase activity
The novel disulfide reductase bis-gamma-glutamylcystine reductase and dihydrolipoamide dehydrogenase from Halobacterium halobium: Purification by immobilized-metal-ion affinity chromatography and properties of the enzymes