Reference on EC 1.7.3.3 - factor-independent urate hydroxylase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Theimer, R.R.; Beevers, H.
Uricase and allantoinase in glyoxysomes
Plant Physiol.
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246-251
1971
Arachis hypogaea, Carthamus tinctorius, Ricinus communis, Helianthus sp., Pinus monophylla, Yucca brevifolia, Zea mays
Yeldandi, A.V.; Wang, X.; Alvares, K.; Kumar, S.; Sambasiva Rao, M.; Reddy, J.K.
Human urate oxidase gene: cloning and partial sequence analysis reveal a stop codon within the fifth exon
Biochem. Biophys. Res. Commun.
171
641-646
1990
Homo sapiens
Motojima, K.; Goto, S.
Cloning of rabbit uricase cDNA reveals a conserved carboxy-terminal tripeptide in three species
Biochim. Biophys. Acta
1008
116-118
1989
Oryctolagus cuniculus
Adamek, V.; Kralova, B.; Suchova, M.; Valentova, O.; Demnerova, K.
Purification of microbial uricase
J. Chromatogr.
497
268-275
1989
Cyberlindnera jadinii
Motojima, K.; Kanaya, S.; Goto, S.
Cloning and sequence analysis of cDNA for rat liver uricase
J. Biol. Chem.
263
16677-16681
1988
Rattus norvegicus
Lee, C.C.; Wu, X.; Gibbs, R.A.; Cook, R.G.; Muzny, D.M.; Caskey, C.T.
Generation of cDNA probes directed by amino acid sequence: cloning of urate oxidase
Science
239
1288-1291
1988
Sus scrofa
Sanchez, F.; Campos, F.; Padilla, J.; Bonneville, J.M.; Enriquez, C.; Caput, D.
Purification, cDNA cloning, and developmental expression of the nodule-specific uricase from Phaseolus vulgaris L.
Plant Physiol.
84
1143-1147
1987
Phaseolus vulgaris
Kral, L.G.; Johnson, D.H.; Burnett, J.B.; Friedman, T.B.
Cloning a cDNA for Drosophila melanogaster urate oxidase
Gene
45
131-137
1986
Drosophila melanogaster
Demnerova, K.; Kralova, B.; Lehejckova, R.; Adamek, V.
Production of uricase by different strains of Streptomyces
Biotechnol. Lett.
8
577-578
1986
Kitasatospora aureofaciens
-
Van den Bosch, K.A.; Newcomb, E.H.
Immunogold localization of nodule-specific uricase in developing soybean root nodules
Planta
167
425-436
1986
Glycine max
Kralova, B.; Lehejckova, R.; Demnerova, K.; Dobransky, T.
Extraction of uricase from Candida utilis
Biotechnol. Lett.
8
99-102
1986
Cyberlindnera jadinii
-
Salas, J.A.; Johnstone, K.; Ellar, D.J.
Role of uricase in the triggering of germination of Bacillus fastidiosus spores
Biochem. J.
229
241-249
1985
Metabacillus fastidiosus
Lucas, K.; Boland, M.J.; Schubert, K.R.
Uricase from soybean root nodules: purification, properties, and comparison with the enzyme from cowpea
Arch. Biochem. Biophys.
226
190-197
1983
Glycine max
Nishimura, H.; Yoshida, K.; Yokota, Y.; Matsushima, A.; Inada, Y.
Physicochemical properties and states of sulfhydryl groups of uricase from Candida utilis
J. Biochem.
91
41-48
1982
Cyberlindnera jadinii
Chen, R.H.L.; Abuchowski, A.; Van Es, T.; Palczuk, N.C.; Davis, F.F.
Properties of two urate oxidases modified by the covalent attachment of poly(ethylene glycol)
Biochim. Biophys. Acta
660
293-298
1981
Cyberlindnera jadinii, Sus scrofa
Ohe, T.; Watanabe, Y.
Purification and properties of urate oxidase from Streptomyces cyanogenus
J. Biochem.
89
1769-1776
1981
Streptomyces cyanogenus
Rainbird, R.M.; Atkins, C.A.
Purification and some properties of urate oxidase from nitrogen-fixing nodules of cowpea
Biochim. Biophys. Acta
659
132-140
1981
Vigna unguiculata
Machida, Y.; Nakanishi, T.
Purification and properties of uricase from Enterobacter cloacae
Agric. Biol. Chem.
44
2811-2815
1980
Enterobacter cloacae
-
Conley, T.G.; Priest, D.G.
Non-classical inhibition of uricase by cyanide
Biochem. J.
187
733-738
1980
Aspergillus flavus
Wang, L.W.C.; Marzluf, G.A.
Purification and characterization of uricase, a nitrogen-regulated enzyme, from Neurospora crassa
Arch. Biochem. Biophys.
201
185-193
1980
Neurospora crassa
Bongaerts, G.P.A.; Vogels, G.D.
Mechanism of uricase action
Biochim. Biophys. Acta
567
295-308
1979
Metabacillus fastidiosus
Bongaerts, G.P.A.; Uitzetter, J.; Brouns, R.; Vogels, G.D.
Uricase of Bacillus fastidiosus. Properties and regulation of synthesis
Biochim. Biophys. Acta
527
348-358
1978
Metabacillus fastidiosus
Mahler, J.L.
A new bacterial uricase for uric acid determination
Anal. Biochem.
38
65-84
1970
Metabacillus fastidiosus
Watanabe, T.; Suga, T.
A simple purification method for rat liver urate oxidase
Anal. Biochem.
89
343-347
1978
Rattus norvegicus
Johnson, D.B.; Coughlan, M.P.
Studies on the stability of immobilized xanthine oxidase and urate oxidase
Biotechnol. Bioeng.
20
1085-1095
1978
Sus scrofa
Antonenkov, V.D.; Pachenko, L.F.
Organization of urate oxidase in peroxisomal nucleoids
FEBS Lett.
88
151-154
1978
Rattus norvegicus
Tanaka, A.; Yamamura, M.; Kawamoto, S.; Fukui, S.
Production of uricase by Candida tropicalis using n-alkane as a substrate
Appl. Environ. Microbiol.
34
342-346
1977
Candida tropicalis
Hinberg, I.; O'Driscoll, K.F.
Preparation and kinetic properties of gel entrapped urate oxidase
Biotechnol. Bioeng.
17
1435-1441
1975
Sus scrofa
Sedor, F.A.; Sander, E.G.
Inhibition of uricase by substituted pyrimidines
Biochem. Biophys. Res. Commun.
75
406-413
1977
Sus scrofa
Johnson, D.B.; Coughlan, M.P.
Characterization of immobilized urate oxidase
Biochem. Soc. Trans.
2
1362-1363
1974
Sus scrofa
-
Pitts, O.M.; Priest, D.G.; Fish, W.W.
Uricase, subunit composition and resistance to denaturants
Biochemistry
13
888-892
1974
Sus scrofa
Truscoe, R.
Effect of detergents on extraction and activity of ox-kidney urate oxidase
Enzymologia
33
19-32
1967
Bos taurus
Truscoe, R.
Effects of some nitrogenous bases on the activity of ox-kidney urate oxidase
Enzymologia
34
337-343
1968
Bos taurus
Truscoe, R.
Effect of borate on urate oxidase activity
Enzymologia
34
325-336
1968
Bos taurus, Sus scrofa
-
Truscoe, R.
Effect of phosphate on the activity of ox-kidney urate oxidase
Enzymologia
35
19-30
1968
Bos taurus
James, K.A.C.; Tate, W.P.; Truscoe, R.
Effects of treatment with dithiothreitol on the extraction, activity and purification of ox-kidney urate oxidase
Enzymologia
37
131-152
1969
Bos taurus
Bentley, K.W.; Truscoe, R.
Effect of guanidine derivates on urate oxidase activity
Enzymologia
37
285-313
1969
Bos taurus
Turner, J.C.; Truscoe, R.
Effect of copper on urate oxidase
Enzymologia
43
57-70
1972
Bos taurus
Christen, P.; Peacock, W.C.; Christen, A.E.; Wacker, W.E.C.
Urate oxidase in primate phylogenesis
Eur. J. Biochem.
12
3-5
1970
Oryctolagus cuniculus, Platyrrhini, Tupaia glis
Parish, R.W.
Urate oxidase in peroxisomes from maize root tips
Planta
104
247-251
1972
Zea mays
Itaya, K.; Fukumoto, J.; Yamamoto, T.
Studies on urate oxidase of Candida utilis. Part II. Some physical and chemical properties of the purified enzyme
Agric. Biol. Chem.
35
813-821
1971
Cyberlindnera jadinii
-
Townsend, D.; Lata, G.F.
Purification of urate oxidase; a sex dependent enzyme from rat liver
Arch. Biochem. Biophys.
135
166-172
1969
Rattus norvegicus
Muller, M.; Moller, K.M.
Urate oxidase and its association with peroxysomes in Acanthamoeba sp.
Eur. J. Biochem.
9
424-430
1969
Acanthamoeba sp.
Nose, K.; Arima, K.
Studies on bacterial urate:oxygen oxidoreductase II. Observations concerning the properties and components of the active site
Biochim. Biophys. Acta
151
63-69
1968
Arthrobacter pascens
Arima, K.; Nose, K.
Studies on bacterial urate:oxygen oxidoreductase I. Purification and properties of the enzyme
Biochim. Biophys. Acta
151
54-62
1968
Arthrobacter pascens
Parish, R.W.
Mitochondria and peroxisomes from the cellular slime mould Dictyostelium discoideum. Isolation techniques and urate oxidase association with peroxisomes
Eur. J. Biochem.
58
523-531
1975
Dictyostelium discoideum
Fitzpatrick, D.A.; McGeeney, K.F.
Resistance of urate oxidase to proteolytic digestion
Biochem. Soc. Trans.
3
1253-1255
1975
Aspergillus flavus, Metabacillus fastidiosus, Cyberlindnera jadinii
-
Theimer, R.R.; Heidinger, P.
Control of particulate urate oxidase activity in bean roots by external nitrogen supply
Z. Pflanzenphysiol.
73
360-370
1974
Phaseolus coccineus
-
Itaya, K.; Yamamoto, T.; Fukumoto, J.
Studies on yeast uricase. Part I. Purification and some enzymatic properties of yeast uricase
Agric. Biol. Chem.
31
1256-1264
1967
Cyberlindnera jadinii
-
Hongoh, Y.; Sasaki, T.; Ishikawa, H.
Cloning, sequence analysis and expression in Escherichia coli of the gene encoding a uricase from the yeast-like symbiont of the brown planthopper, Nilaparvata lugens
Insect Biochem. Mol. Biol.
30
173-182
2000
yeast-like fungi
Kahn, K.; Tipton, P.A.
Kinetic mechanism and cofactor content of soybean root nodule urate oxidase
Biochemistry
36
4731-4738
1997
Glycine max
Nishiya, Y.; Hibi, T.; Oda, J.
A purification method of the diagnostic enzyme Bacillus uricase using magnetic beads and non-specific protease
Protein Expr. Purif.
25
426
2002
Bacillus sp. (in: Bacteria), Bacillus sp. (in: Bacteria) TB-90
Jianguo, L.; Gaoxiang, L.; Hong, L.; Xiukai, Z.
Purification and properties of uricase from Candida sp. and its application in uric acid analysis in serum
Appl. Biochem. Biotechnol.
47
57-63
1994
Candida sp. (in: Saccharomycetales)
Aguilar, M.; Montalbini, P.; Pineda, M.
Urate oxidase from the rust Puccinia recondita is a heterotetramer with two different-sized monomers
Curr. Microbiol.
44
257-261
2002
Puccinia recondita
Kahn, K.; Tipton, P.A.
Spectroscopic Characterization of Intermediates in the Urate Oxidase Reaction
Biochemistry
37
11651-11659
1998
Glycine max
Schiavon, O.; Caliceti, P.; Ferruti, P.; Veronese, F.M.
Therapeutic proteins: a comparison of chemical and biological properties of uricase conjugated to linear or branched poly(ethylene glycol) and poly(N-acryloylmorpholine)
Farmaco
55
264-269
2000
Metabacillus fastidiosus
Leal-Pinto, E.; London, R.D.; Knorr, B.A.; Abramson, R.G.
Reconstitution of hepatic uricase in planar lipid bilayer reveals a functional organic anion channel
J. Membr. Biol.
146
123-132
1995
Rattus norvegicus, Sus scrofa
Kahn, K.; Serfozo, P.; Tipton, P.A.
Identification of the true product of the urate oxidase reaction
J. Am. Chem. Soc.
119
5435-5442
1997
Glycine max
-
Montalbini, P.; Redondo, J.; Caballero, J.L.; Cardenas, J.; Pineda, M.
Uricase from leaves. Its purification and characterization from three different higher plants
Planta
202
277-283
1997
Vicia faba, Cicer arietinum, Triticum aestivum
-
Capote-Mainez, N.; Sanchez, F.
Characterization of the common bean uricase II and its expression in organs other than nodules
Plant Physiol.
115
1307-1317
1997
Phaseolus vulgaris
Montalbini, P.; Aguilar, M.; Pineda, M.
Isolation and characterization of uricase from bean leaves and its comparison with uredospore enzymes
Plant Sci.
147
139-147
1999
Vicia faba, Phaseolus vulgaris, Uromyces viciae-fabae, Uromyces phaseoli
-
Vivares, D.; Bonnete, F.
X-ray scattering studies of Aspergillus flavus urate oxidase: towards a better understanding of PEG effects on the crystallization of large proteins
Acta Crystallogr. Sect. D
58
472-479
2002
Aspergillus flavus
Retailleau, P.; Colloc'h, N.; Vivares, D.; Bonnete, F.; Castro, B.; El-Hajji, M.; Mornon, J.P.; Monard, G.; Prange, T.
Complexed and ligand-free high-resolution structures of urate oxidase (Uox) from Aspergillus flavus: a reassignment of the active-site binding mode
Acta Crystallogr. Sect. D
60
453-462
2004
Aspergillus flavus
Retailleau, P.; Colloc'h, N.; Vivares, D.; Bonnete, F.; Castro, B.; El Hajji, M.; Prange, T.
Urate oxidase from Aspergillus flavus: new crystal-packing contacts in relation to the content of the active site
Acta Crystallogr. Sect. D
61
218-229
2005
Aspergillus flavus
Fraisse, L.; Bonnet, M.C.; de Farcy, J.P.; Agut, C.; Dersigny, D.; Bayol, A.
A colorimetric 96-well microtiter plate assay for the determination of urate oxidase activity and its kinetic parameters
Anal. Biochem.
309
173-179
2002
Aspergillus flavus (Q00511)
Huang, Y.; Ito, R.; Miura, S.; Yokota, S.; Oda, T.; Ito, M.
Altered antigenic disposition of peroxisomal urate oxidase in PEX5-defective Chinese hamster ovary cells
Biochem. Biophys. Res. Commun.
302
703-709
2003
Cricetulus griseus
Imhoff, R.D.; Power, N.P.; Borrok, M.J.; Tipton, P.A.
General base catalysis in the urate oxidase reaction: evidence for a novel Thr-Lys catalytic diad
Biochemistry
42
4094-4100
2003
Bacillus subtilis
Bayol, A.; Capdevielle, J.; Malazzi, P.; Buzy, A.; Claude Bonnet, M.; Colloc'h, N.; Mornon, J.P.; Loyaux, D.; Ferrara, P.
Modification of a reactive cysteine explains differences between rasburicase and uricozyme, a natural Aspergillus flavus uricase
Biotechnol. Appl. Biochem.
36
21-31
2002
Aspergillus flavus, Aspergillus flavus (Q00511)
Farley, P.C.; Santosa, S.
Regulation of expression of the Rhizopus oryzae uricase and urease enzymes
Can. J. Microbiol.
48
1104-1108
2002
Rhizopus arrhizus
Huang, S.H.; Wu, T.K.
Modified colorimetric assay for uricase activity and a screen for mutant Bacillus subtilis uricase genes following StEP mutagenesis
Eur. J. Biochem.
271
517-523
2004
Bacillus subtilis
Suzuki, K.; Sakasegawa, S.I.; Misaki, H.; Sugiyama, M.
Molecular cloning and expression of uricase gene from Arthrobacter globiformis in Escherichia coli and characterization of the gene product
J. Biosci. Bioeng.
98
153-158
2004
Arthrobacter globiformis, Arthrobacter globiformis FERM BP-360
Tipton, P.A.
Urate oxidase:single-turnover stopped-flow techniques for detecting two discrete enzyme-bound intermediates
Methods Enzymol.
354
310-319
2002
Glycine max
Montalbini, P.; Aguilar, M.; Caballero, J.L.; Piedras, P.; Redondo, J.; Pineda, M.
Purification, quantification and gene expression of urate oxidases in rust-infected bean leaves
Physiol. Mol. Plant Pathol.
61
141-150
2002
Phaseolus vulgaris
Redondo-Nevado, J.; Aguilar, M.; Caballero, J.L.; Pineda, M.
Structural and genomic organization, cDNA characterization and expression analysis of the urate oxidase gene from chickpea (Cicer arietinum)
Physiol. Plant.
121
358-368
2004
Cicer arietinum (Q9LD80)
-
Saeed, H.M.; Abdel-Fattah, Y.R.; Gohar, Y.M.; Elbaz, M.A.
Purification and characterization of extracellular Pseudomonas aeruginosa urate oxidase enzyme
Pol. J. Microbiol.
53
45-52
2004
Pseudomonas aeruginosa
Kim, W.K.; Patterson, P.H.
Production of an egg yolk antibody specific to microbial uricase and its inhibitory effects on uricase activity
Poult. Sci.
82
1554-1558
2003
Arthrobacter globiformis
Budayova-Spano, M.; Bonnete, F.; Ferte, N.; El Hajji, M.; Meilleur, F.; Blakeley, M.P.; Castro, B.
A preliminary neutron diffraction study of rasburicase, a recombinant urate oxidase enzyme, complexed with 8-azaxanthin
Acta crystallogr. Sect. F
62
306-309
2006
Aspergillus flavus
Doll, C.; Bell, A.F.; Power, N.; Tonge, P.J.; Tipton, P.A.
Procatalytic ligand strain. Ionization and perturbation of 8-nitroxanthine at the urate oxidase active site
Biochemistry
44
11440-11446
2005
Bacillus subtilis
Colloch, N.; Girard, E.; Dhaussy, A.; Kahn, R.; Ascone, I.; Mezouar, M.; Fourme, R.
High pressure macromolecular crystallography: The 140-MPa crystal structure at 2.3 A resolution of urate oxidase, a 135-kDa tetrameric assembly
Biochim. Biophys. Acta
1764
391-397
2006
Aspergillus flavus
Zhao, Y.; Zhao, L.; Yang, G.; Tao, J.; Bu, Y.; Liao, F.
Characterization of an uricase from Bacillus fastidious A.T.C.C. 26904 and its application to serum uric acid assay by a patented kinetic uricase method
Biotechnol. Appl. Biochem.
45
75-80
2006
Metabacillus fastidiosus
Andersen, O.; Aas, T.S.; Skugor, S.; Takle, H.; van Nes, S.; Grisdale-Helland, B.; Helland, S.J.; Terjesen, B.F.
Purine-induced expression of urate oxidase and enzyme activity in Atlantic salmon (Salmo salar). Cloning of urate oxidase liver cDNA from three teleost species and the African lungfish Protopterus annectens
FEBS J.
273
2839-2850
2006
Gadus morhua (Q3S561), Gadus morhua, Hippoglossus hippoglossus (Q3S560), Hippoglossus hippoglossus, Protopterus annectens (Q3S562), Protopterus annectens, Salmo salar (Q3S563), Salmo salar
Gabison, L.; Chiadmi, M.; Colloch, N.; Castro, B.; El Hajji, M.; Prange, T.
Recapture of [S]-allantoin, the product of the two-step degradation of uric acid, by urate oxidase
FEBS Lett.
580
2087-2091
2006
Aspergillus flavus (Q00511), Aspergillus flavus
Pan, J.; Pan, X.; Wang, N.; Ghazizadeh, M.; Yeldandi, A.
Characterization of the degradation of recombinant rat urate oxidase in tetracycline controlled gene expression cells
J. Electron Microsc. (Tokyo)
54
385-392
2005
Rattus norvegicus
Abdel-Fattah, Y.R.; Saeed, H.M.; Gohar, Y.M.; El-Baz, M.A.
Improved production of Pseudomonas aeruginosa uricase by optimization of process parameters through statistical experimental designs
Process Biochem.
40
1707-1714
2005
Pseudomonas aeruginosa
-
Li, J.; Chen, Z.; Hou, L.; Fan, H.; Weng, S.; Xu, C.; Ren, J.; Li, B.; Chen, W.
High-level expression, purification, and characterization of non-tagged Aspergillus flavus urate oxidase in Escherichia coli
Protein Expr. Purif.
49
55-59
2006
Aspergillus flavus
Rajoka, M.I.; Rehman, K.U.; Mehraj, M.; Akhtar, M.W.; Zia, M.A.
Purification, and properties of a bovine uricase
Protein Pept. Lett.
13
363-368
2006
Bos taurus
Rajoka, M.I.; Khalil-ur-Rehma, K.; Tabish, T.; Zia, M.A.
Purification and characterization of caprine kidney uricase, possessing novel kinetic and thermodynamic properties
World J. Microbiol. Biotechnol.
22
289-291
2006
Capra sp.
Juan, E.; Hoque, M.; Shimizu, S.; Hossain, M.; Yamamoto, T.; Imamura, S.; Suzuki, K.; Tsunoda, M.; Amano, H.; Sekiguchi, T.; Takenaka, A.
Structures of Arthrobacter globiformis urate oxidase-ligand complexes
ACTA CRYSTALLOGR. SECT. D
64
815-822
2008
Arthrobacter globiformis (D0VWQ1), Arthrobacter globiformis
Chen, Z.; Wang, Z.; He, X.; Guo, X.; Li, W.; Zhang, B.
Uricase production by a recombinant Hansenula polymorpha strain harboring Candida utilis uricase gene
Appl. Microbiol. Biotechnol.
79
545-554
2008
Cyberlindnera jadinii
Sundy, J.S.; Ganson, N.J.; Kelly, S.J.; Scarlett, E.L.; Rehrig, C.D.; Huang, W.; Hershfield, M.S.
Pharmacokinetics and pharmacodynamics of intravenous PEGylated recombinant mammalian urate oxidase in patients with refractory gout
Arthritis Rheum.
56
1021-1028
2007
Sus scrofa (P16164)
Pession, A.; Melchionda, F.; Castellini, C.
Pitfalls, prevention, and treatment of hyperuricemia during tumor lysis syndrome in the era of rasburicase (recombinant urate oxidase)
Biologics
2
129-141
2008
Saccharomyces cerevisiae
Colloc'h, N.; Gabison, L.; Monard, G.; Altarsha, M.; Chiadmi, M.; Marassio, G.; Sopkova-de Oliveira Santos, J.; El Hajji, M.; Castro, B.; Abraini, J.H.; Prange, T.
Oxygen pressurized X-ray crystallography: probing the dioxygen binding site in cofactorless urate oxidase and implications for its catalytic mechanism
Biophys. J.
95
2415-2422
2008
Aspergillus flavus (Q00511)
Lotfy, W.
Production of a thermostable uricase by a novel Bacillus thermocatenulatus strain
Biores. Technol.
99
699-702
2008
Geobacillus thermocatenulatus (DQ887577), Geobacillus thermocatenulatus
Gabison, L.; Prange, T.; Colloch, N.; El Hajji, M.; Castro, B.; Chiadmi, M.
Structural analysis of urate oxidase in complex with its natural substrate inhibited by cyanide: mechanistic implications
BMC Struct. Biol.
8
32
2008
Aspergillus flavus (Q00511)
Oksanen, E.; Blakeley, M.P.; Bonnete, F.; Dauvergne, M.T.; Dauvergne, F.; Budayova-Spano, M.
Large crystal growth by thermal control allows combined X-ray and neutron crystallographic studies to elucidate the protonation states in Aspergillus flavus urate oxidase
J. R. Soc. Interface
6 Suppl 5
599-610
2009
Aspergillus flavus
Liu, Z.; Lu, D.; Li, J.; Chen, W.; Liu, Z.
Strengthening intersubunit hydrogen bonds for enhanced stability of recombinant urate oxidase from Aspergillus flavus: molecular simulations and experimental validation
Phys. Chem. Chem. Phys.
11
333-340
2009
Aspergillus flavus (Q00511), Aspergillus flavus
Scaraffia, P.Y.; Tan, G.; Isoe, J.; Wysocki, V.H.; Wells, M.A.; Miesfeld, R.L.
Discovery of an alternate metabolic pathway for urea synthesis in adult Aedes aegypti mosquitoes
Proc. Natl. Acad. Sci. USA
105
518-523
2008
Aedes aegypti (Q17J02), Aedes aegypti, Aedes aegypti NH-Rockefeller (Q17J02)
Chen, M.; Cai, L.; Fang, Z.; Tian, H.; Gao, X.; Yao, W.
Site-specific incorporation of unnatural amino acids into urate oxidase in Escherichia coli
Protein Sci.
17
1827-1833
2008
Cyberlindnera jadinii
Kai, L.; Ma, X.; Zhou, X.; Jia, X.; Li, X.; Guo, K.
Purification and characterization of a thermostable uricase from Microbacterium sp. strain ZZJ4-1
World J. Microbiol. Biotechnol.
24
401-406
2008
Microbacterium sp., Microbacterium sp. ZZJ4-1
Collings, I.; Watier, Y.; Giffard, M.; Dagogo, S.; Kahn, R.; Bonnete, F.; Wright, J.P.; Fitch, A.N.; Margiolaki, I.
Polymorphism of microcrystalline urate oxidase from Aspergillus flavus
Acta Crystallogr. Sect. D
66
539-548
2010
Aspergillus flavus (Q00511), Aspergillus flavus
Zhao, Y.; Yang, X.; Li, X.; Bu, Y.; Deng, P.; Zhang, C.; Feng, J.; Xie, Y.; Zhu, S.; Yuan, H.; Yu, M.; Liao, F.
Reversible inactivation of an intracellular uricase from Bacillus fastidiosus via dissociation of homotetramer into homodimers in solutions of low ionic strength
Biosci. Biotechnol. Biochem.
73
2141-2144
2009
Metabacillus fastidiosus (C5HDG5), Metabacillus fastidiosus, Metabacillus fastidiosus ATCC 26904 (C5HDG5)
Zhang, C.; Yang, X.; Feng, J.; Yuan, Y.; Li, X.; Bu, Y.; Xie, Y.; Yuan, H.; Liao, F.
Effects of modification of amino groups with poly(ethylene glycol) on a recombinant uricase from Bacillus fastidiosus
Biosci. Biotechnol. Biochem.
74
1298-1301
2010
Metabacillus fastidiosus (C5HDG5), Metabacillus fastidiosus, Metabacillus fastidiosus ATCC 29604 (C5HDG5)
Tan, Q.Y.; Wang, N.; Yang, H.; Zhang, L.K.; Liu, S.; Chen, L.; Liu, J.; Zhang, L.; Hu, N.N.; Zhao, C.J.; Zhang, J.Q.
Characterization, stabilization and activity of uricase loaded in lipid vesicles
Int. J. Pharm.
384
165-172
2010
Cyberlindnera jadinii
Pfrimer, P.; de Moraes, L.M.; Galdino, A.S.; Salles, L.P.; Reis, V.C.; De Marco, J.L.; Prates, M.V.; Bloch, C.; Torres, F.A.
Cloning, purification, and partial characterization of Bacillus subtilis urate oxidase expressed in Escherichia coli
J. Biomed. Biotechnol.
2010
674908
2010
Bacillus subtilis, Bacillus subtilis LMD 69.3
Estarellas, C.; Frontera, A.; Quinonero, D.; Deya, P.
Relevant anion-π interactions in biological systems: The case of urate oxidase
Angew. Chem. Int. Ed. Engl.
50
415-418
2011
Aspergillus flavus (Q00511)
Liu, X.; Wen, M.; Li, J.; Zhai, F.; Ruan, J.; Zhang, L.; Li, S.
High-yield expression, purification, characterization, and structure determination of tag-free Candida utilis uricase
Appl. Microbiol. Biotechnol.
92
529-537
2011
Cyberlindnera jadinii (P78609), Cyberlindnera jadinii
Geweely, N.; Nawar, L.
Production, optimization, purification and properties of uricase isolated from some fungal flora in Saudi Arabian soil
Aust. J. Basic Appl. Sci.
5
220-230
2011
Aspergillus niger
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Caves, M.S.; Derham, B.K.; Jezek, J.; Freedman, R.B.
Thermal inactivation of uricase (urate oxidase): mechanism and effects of additives
Biochemistry
52
497-507
2013
Candida sp. (in: Saccharomycetales)
Zhang, C.; Fan, K.; Zhang, W.; Zhu, R.; Zhang, L.; Wei, D.
Structure-based characterization of canine-human chimeric uricases and its evolutionary implications
Biochimie
94
1412-1420
2012
Canis lupus familiaris (Q5FZI9), Canis lupus familiaris
Dmytruk, K.; Smutok, O.; Dmytruk, O.; Schuhmann, W.; Sibirny, A.
Construction of uricase-overproducing strains of Hansenula polymorpha and its application as biological recognition element in microbial urate biosensor
BMC Biotechnol.
11
58
2011
Ogataea angusta
Fang, Z.; Liu, Y.; Liu, J.; Sun, R.; Chen, H.; Gao, X.; Yao, W.
Designing and engineering of a site-specific incorporation of a keto group in uricase
Chem. Biol. Drug Des.
78
353-360
2011
Methanocaldococcus jannaschii
Wei, D.; Huang, X.; Qiao, Y.; Rao, J.; Wang, L.; Liao, F.; Zhan, C.
Catalytic mechanisms for cofactor-free oxidase-catalyzed reactions reaction pathways of uricase-catalyzed oxidation and hydration of uric acid
ACS Catal.
7
4623-4636
2017
Aspergillus flavus (Q00511)
Feng, T.; Yang, X.; Wang, D.; Hu, X.; Liao, J.; Pu, J.; Zhao, X.; Zhan, C.G.; Liao, F.
A practical system for high-throughput screening of mutants of Bacillus fastidiosus uricase
Appl. Biochem. Biotechnol.
181
667-681
2017
Metabacillus fastidiosus (C5HDG5), Metabacillus fastidiosus
Feng, J.; Wang, L.; Liu, H.; Yang, X.; Liu, L.; Xie, Y.; Liu, M.; Zhao, Y.; Li, X.; Wang, D.; Zhan, C.G.; Liao, F.
Crystal structure of Bacillus fastidious uricase reveals an unexpected folding of the C-terminus residues crucial for thermostability under physiological conditions
Appl. Microbiol. Biotechnol.
99
7973-7986
2015
Metabacillus fastidiosus (C5HDG5), Metabacillus fastidiosus ATCC 29604 (C5HDG5)
Khade, S.; Srivastava, S.; Tripathi, A.
Production of clinically efficient uricase enzyme induced from different strains of Pseudomonas aeruginosa under submerged fermentations and their kinetic properties
Biocatal. Agricult. Biotechnol.
8
139-145
2016
Pseudomonas aeruginosa, Pseudomonas aeruginosa 5Y2, Pseudomonas aeruginosa Ph3
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Xiong, R.; Umar, S.; Chen, J.
Process for production of recombinant baboon uricase in Escherichia coli Rosetta (DE3)
Biotechnol. Biotechnol. Equip.
27
4141-4144
2013
Papio sp.
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Feng, J.; Liu, H.; Yang, X.; Gao, A.; Liao, J.; Feng, L.; Pu, J.; Xie, Y.; Long, G.; Li, Y.; Liao, F.
Comparison of activity indexes for recognizing enzyme mutants of higher activity with uricase as model
Chem. Cent. J.
7
69
2013
Metabacillus fastidiosus (C5HDG5)
Alishah, K.; Asad, S.; Khajeh, K.; Akbari, N.
Utilizing intein-mediated protein cleaving for purification of uricase, a multimeric enzyme
Enzyme Microb. Technol.
93-94
92-98
2016
Aspergillus flavus (Q00511), Aspergillus flavus
Digumarti, R.; Sinha, S.; Nirni, S.S.; Patil, S.G.; Pedapenki, R.M.
Efficacy of rasburicase (recombinant urate oxidase) in the prevention and treatment of malignancy-associated hyperuricemia an Indian experience
Indian J. Cancer
51
180-183
2014
Aspergillus flavus
Shaaban, M.I.; Abdelmegeed, E.; Ali, Y.M.
Cloning, expression, and purification of recombinant uricase enzyme from Pseudomonas aeruginosa Ps43 using Escherichia coli
J. Microbiol. Biotechnol.
25
887-892
2015
Pseudomonas aeruginosa (A0A0B4N4Y1), Pseudomonas aeruginosa, Pseudomonas aeruginosa Ps43 (A0A0B4N4Y1), Pseudomonas aeruginosa Ps43
Ram, S.K.; Raval, K.; JagadeeshBabu, P.E.
Enhancement of a novel extracellular uricase production by media optimization and partial purification by aqueous three-phase system
Prep. Biochem. Biotechnol.
45
810-824
2015
Xanthomonas citri pv. aurantifolii
Kratzer, J.T.; Lanaspa, M.A.; Murphy, M.N.; Cicerchi, C.; Graves, C.L.; Tipton, P.A.; Ortlund, E.A.; Johnson, R.J.; Gaucher, E.A.
Evolutionary history and metabolic insights of ancient mammalian uricases
Proc. Natl. Acad. Sci. USA
111
3763-3768
2014
Mammalia
Ravichandran, R.; Hemaasri, S.; Cameotra, S.S.; Jayaprakash, N.S.
Purification and characterization of an extracellular uricase from a new isolate of Sphingobacterium thalpophilum (VITPCB5)
Protein Expr. Purif.
114
136-142
2015
Sphingobacterium thalpophilum (JX083378), Sphingobacterium thalpophilum, Sphingobacterium thalpophilum VITPCB5 (JX083378)
Wu, J.; Yang, X.; Wang, D.; Hu, X.; Liao, J.; Rao, J.; Pu, J.; Zhan, C.G.; Liao, F.
A numerical approach for kinetic analysis of the nonexponential thermoinactivation process of uricase
Protein J.
35
318-329
2016
Candida sp. (in: Saccharomycetales)
Kotb, E.
Characterization of a thermostable uricase isolated from Bacillus firmus DWD-33 and its application for uric acid quantification in human serum
Protein Pept. Lett.
22
402-409
2015
Cytobacillus firmus, Cytobacillus firmus DWD-33
Atalla, S.; El-Shamy, A.
Optimization of uricase by Aspergillus terreus NRC 7
World Appl. Sci. J.
23
871-876
2013
Aspergillus terreus, Aspergillus terreus NRC 7
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Imani, M.; Shahmohamadnejad, S.
Recombinant production of Aspergillus flavus uricase and investigation of its thermal stability in the presence of raffinose and lactose
3 Biotech
7
201
2017
Aspergillus flavus
Wang, B.; Luo, L.; Wang, D.; Ding, R.; Hong, J.
Efficient purification of a recombinant tag-free thermostable Kluyveromyces marxianus uricase by pH-induced self-cleavage of intein and expression in Escherichia coli
3 Biotech
8
400
2018
Kluyveromyces marxianus, Kluyveromyces marxianus NBRC 1777
Shi, Y.; Wang, T.; Zhou, X.E.; Liu, Q.F.; Jiang, Y.; Xu, H.E.
Structure-based design of a hyperthermostable AgUricase for hyperuricemia and gout therapy
Acta Pharmacol. Sin.
40
1364-1372
2019
Arthrobacter globiformis (D0VWQ1), Arthrobacter globiformis
Liu, D.; Yang, P.; Wang, F.; Wang, C.; Chen, L.; Ye, S.; Dramou, P.; Chen, J.; He, H.
Study on performance of mimic uricase and its application in enzyme-free analysis
Anal. Bioanal. Chem.
413
6571-6580
2021
nanozyme
Phuadraksa, T.; Chittrakanwong, J.; Tullayaprayouch, K.; Onsirisakul, N.; Wichit, S.; Yainoy, S.
Engineering of bifunctional enzymes with uricase and peroxidase activities for simple and rapid quantification of uric acid in biological samples
Catalysts
10
428
2020
Cyberlindnera jadinii
-
RoyChoudhury, S.; Umasankar, Y.; Hutcheson, J.; Lev-Tov, H.; Kirsner, R.; Bhansali, S.
Uricase based enzymatic biosensor for non-invasive detection of uric acid by entrapment in PVA-SbQ polymer matrix
Electroanalysis
30
2374-2385
2018
unidentified
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Rajagopalan, P.; Chandramoorthy, H.; Elbessoumy, A.
Pilot scale production and characterization of uricase from Penicillium purpurescens
Indian J. Biotechnol.
16
570-577
2017
Penicillium purpurescens, Penicillium purpurescens ATCC 10485
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Hu, X.; Wang, Y.; Liu, C.; Jin, Z.; Tian, Y.
Dextrin-uricase conjugate Preparation, characterization, and enzymatic properties
Int. J. Biol. Macromol.
111
28-32
2018
Candida sp. (in: Saccharomycetales)
Tork, S.E.; Aly, M.M.; Al-Fattani, S.Q.
A new uricase from Bacillus cereus SKIII Characterization, gene identification and genetic improvement
Int. J. Biol. Macromol.
165
3135-3144
2020
Bacillus cereus, Bacillus cereus SKIII
Yainoy, S.; Phuadraksa, T.; Wichit, S.; Sompoppokakul, M.; Songtawee, N.; Prachayasittikul, V.; Isarankura-Na-Ayudhya, C.
Production and characterization of recombinant wild type uricase from indonesian coelacanth (L. menadoensis) and improvement of its thermostability by in silico rational design and disulphide bridges engineering
Int. J. Mol. Sci.
20
1269
2019
Latimeria menadoensis (U4KJC3), Latimeria menadoensis
Gruia, F.; Parupudi, A.; Baca, M.; Ward, C.; Nyborg, A.; Remmele, R.L.; Bee, J.S.
Impact of mutations on the higher order structure and activity of a recombinant uricase
J. Pharm. Sci.
106
1018-1024
2017
Arthrobacter globiformis
Szczurek, P.; Mosiichuk, N.; Wolinski, J.; Yatsenko, T.; Grujic, D.; Lozinska, L.; Pieszka, M.; Swiech, E.; Pierzynowski, S.G.; Goncharova, K.
Oral uricase eliminates blood uric acid in the hyperuricemic pig model
PLoS ONE
12
e0179195
2017
Cyberlindnera jadinii
Khade, S.; Srivastava, S.; Kumar, K.; Sharma, K.; Goyal, A.; Tripathi, A.
Optimization of clinical uricase production by Bacillus cereus under submerged fermentation, its purification and structure characterization
Process Biochem.
75
49-58
2018
Bacillus cereus, Bacillus cereus MTCC 8550
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Mirzaeinia, S.; Pazhang, M.; Imani, M.; Chaparzadeh, N.; Amani-Ghadim, A.
Improving the stability of uricase from Aspergillus flavus by osmolytes Use of response surface methodology for optimization of the enzyme stability
Process Biochem.
94
86-98
2020
Aspergillus flavus
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Tao, L.; Li, D.; Li, Y.; Shi, X.; Wang, J.; Rao, C.; Zhang, Y.
Designing a mutant Candida uricase with improved polymerization state and enzymatic activity
Protein Eng. Des. Sel.
30
753-759
2017
Candida sp. (in: Saccharomycetales)
Zhou, Z.; Zhao, H.; Zhang, L.; Xie, Q.; Liu, Q.; Tong, M.; Yu, X.; Xiong, S.
Soluble expression of bioactive recombinant porcine-human chimeric uricase mutant employing MBP-SUMO fusion system
Protein Expr. Purif.
189
105978
2022
Sus scrofa
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