Information on EC 1.7.1.B3 - aromatic nitroreductase [NADPH]

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The enzyme appears in viruses and cellular organisms

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EC NUMBER
COMMENTARY hide
1.7.1.B3
preliminary BRENDA-supplied EC number
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RECOMMENDED NAME
GeneOntology No.
aromatic nitroreductase [NADPH]
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REACTION
REACTION DIAGRAM
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ORGANISM
UNIPROT
LITERATURE
an aromatic amine + 3 NADP+ + 2 H2O = an aromatic nitrate + 3 NADPH + 3 H+
show the reaction diagram
in vivo the reaction is obseverved in the opposite direction from that shown in the equation; (overall reaction)
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an aromatic amine + NADP+ + H2O = an aromatic hydroxylamine + NADPH + H+
show the reaction diagram
(1a)
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an aromatic hydroxylamine + NADP+ = an aromatic nitric oxide + NADPH + H+
show the reaction diagram
(1b)
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an aromatic nitric oxide + NADP+ + H2O = an aromatic nitrate + NADPH + H+
show the reaction diagram
(1c)
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SYSTEMATIC NAME
IUBMB Comments
aromatic nitrate:NADPH oxidroreductase
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LINKS TO OTHER DATABASES (specific for EC-Number 1.7.1.B3)
ExplorEnz
ExPASy
KEGG
MetaCyc
SABIO-RK
NCBI: PubMed, Protein, Nucleotide, Structure, Genome, OMIM
IUBMB Enzyme Nomenclature
PROSITE Database of protein families and domains
InterPro (database of protein families, domains and functional sites)