Information on EC 1.7.1.11 - 4-(dimethylamino)phenylazoxybenzene reductase

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The expected taxonomic range for this enzyme is: Rattus norvegicus

top print hide
EC NUMBER
COMMENTARY hide
1.7.1.11
-
top print hide
RECOMMENDED NAME
GeneOntology No.
4-(dimethylamino)phenylazoxybenzene reductase
top print hide
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
4-(dimethylamino)phenylazobenzene + NADP+ + H2O = 4-(dimethylamino)phenylazoxybenzene + NADPH + H+
show the reaction diagram
-
-
-
-
top print hide
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
oxidation
-
-
-
-
redox reaction
-
-
-
-
reduction
-
-
-
-
top print hide
SYSTEMATIC NAME
IUBMB Comments
4-(dimethylamino)phenylazobenzene:NADP+ oxidoreductase
-
top
top print hide
CAS REGISTRY NUMBER
COMMENTARY hide
103843-39-6
-
top print hide
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
-
-
Manually annotated by BRENDA team
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
NADPH + 4-(dimethylamino)phenylazoxybenzene
NADP+ + 4-(dimethylamino)phenylazobenzene
show the reaction diagram
-
highly specific for NADPH and 4-(dimethylamino)phenylazoxybenzene
-
?
top print hide
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
NADPH
-
specific for
top print hide
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.7
4-(dimethylamino)phenylazoxybenzene
-
-
0.021
NADPH
-
-
top print hide
TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2.5
NADPH
Rattus norvegicus
-
-
top print hide
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
top print hide
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
6.5
-
enzyme assay
top print hide
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
37
-
enzyme assay
top print hide
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
top print hide
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
top print hide
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
92000
-
4 * 92000, SDS-PAGE
370000
-
gel filtration
top print hide
SUBUNITS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
tetramer
-
4 * 92000, SDS-PAGE
top print hide
STORAGE STABILITY
ORGANISM
UNIPROT
LITERATURE
-20 C, several weeks
-
top print hide
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
top
top
LINKS TO OTHER DATABASES (specific for EC-Number 1.7.1.11)
ExplorEnz
ExPASy
KEGG
MetaCyc
SABIO-RK
NCBI: PubMed, Protein, Nucleotide, Structure, Genome, OMIM
IUBMB Enzyme Nomenclature
PROSITE Database of protein families and domains
SYSTERS
Protein Mutant Database
InterPro (database of protein families, domains and functional sites)