Information on EC 1.6.5.3 - NADH:ubiquinone reductase (H+-translocating)

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The expected taxonomic range for this enzyme is: Archaea, Bacteria, Eukaryota

EC NUMBER
COMMENTARY hide
1.6.5.3
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RECOMMENDED NAME
GeneOntology No.
NADH:ubiquinone reductase (H+-translocating)
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
NADH + ubiquinone + 6 H+[side 1] = NAD+ + ubiquinol + 7 H+[side 2]
show the reaction diagram
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
oxidation
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redox reaction
reduction
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
aerobic respiration I (cytochrome c)
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aerobic respiration III (alternative oxidase pathway)
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Fe(II) oxidation
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NAD/NADH phosphorylation and dephosphorylation
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NADH to cytochrome bd oxidase electron transfer I
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NADH to cytochrome bo oxidase electron transfer I
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Oxidative phosphorylation
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Metabolic pathways
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SYSTEMATIC NAME
IUBMB Comments
NADH:ubiquinone oxidoreductase
A flavoprotein (FMN) containing iron-sulfur clusters. The complex is present in mitochondria and aerobic bacteria. Breakdown of the complex can release EC 1.6.99.3, NADH dehydrogenase. In photosynthetic bacteria, reversed electron transport through this enzyme can reduce NAD+ to NADH.
CAS REGISTRY NUMBER
COMMENTARY hide
9028-04-0
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Manually annotated by BRENDA team
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
Chlamydomonas sp.
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Manually annotated by BRENDA team
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
var. melopepo, zucchini
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Manually annotated by BRENDA team
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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1026613 A+, 1026615 A+, 1026626 A+, 1026631 A+, 1026647 A+, 1026658 A+, 1026664 A+, 1026668 A+, 1026671 A+, 1026678 A+, 1026679 A+, 1026680 A+, 1026681 A+, 1026693 A+, 1026696 A+, 1026697 A+, 1026707 A+, 1026712 A+, 1026738 A+, 1026764 A+, 1026797 A+, 1026798 A+, 1026819 A+, 1026863 A+, 1026897 A+, 1026927 A+, 1026969 A+, 1027009 A+, 1027011 A+, 1027026 A+, 1027042 A+, 1027047 A+, 1027055 A+, 1027063 A+, 1027074 A+, 1027096 A+, 1027123 A+, 1027129 A+, 1027142 A+, 1031832 A+, 1031912 A+, 1047050 A+, 1048069 A+, 1085273 A+, 1135826 A+, 1218286 A+, 1235133 A+, 1238924 A+, 1270026 A+, 1332329 A+, 1332330 A+, 1337465 A+, 1371455 A+, 1375696 A+, 1414493 A+, 1482114 A+, 1574139 A+, 1633510 A+, 1636632 A+, 1641414 A+, 1642407 A+, 1643019 A+, 1643381 A+, 1643712 A+, 1688484 A+, 1699627 A+, 1732599 A+, 1732915 A+, 1732978 A+, 1733557 A+, 1733636 A+, 1733695 A+, 1738984 A+, 1738985 A+, 1738990 A+, 1738991 A+, 1738992 A+, 1739021 A+, 1739027 A+, 1739040 A+, 1739042 A+, 1739044 A+, 1739050 A+, 1739070 A+, 1739076 A+, 1739086 A+, 1739140 A+, 1739145 A+, 1739154 A+, 1739177 A+, 1739179 A+, 1739249 A+, 1739306 A+, 1739334 A+, 1739337 A+, 1739343 A+, 1739367 A+, 1739378 A+, 1739385 A+, 1739408 A+, 1739463 A+, 1739470 A+, 1739509 A+, 1739515 A+, 1739549 A+, 1739565 A+, 1739570 A+, 1739595 A+, 1739634 A+, 1739644 A+, 1739663 A+, 2253668 A+, 2256892 A+, 2256895 A+, 2256976 A+, 2257000 A+, 2257027 A+, 2257217 A+, 2257218 A+, 2257243 A+, 2257266 A+, 2257276 A+, 2257337 A+, 2257340 A+, 2257379 A+, 2257382 A+, 2257394 A+, 2257401 A+, 2259616 A+, 2259624 A+, 2266986 A+, 2380569 A+, 2409495 A+, 2467034 A+, 2544668 A+, 2639007 A+, 2653451 A+, 2668510 A+, 2711354 A+, 2735215 A+, 2762344 A+, 2762402 A+, 2765481 A+, 2766063 A+, 2788989 A+, 2789178 A+, 2789297 A+, 2789375 A+, 2789536 A+, 2794249 A+, 2794259 A+, 2794283 A+, 2794297 A+, 2794300 A+, 2794307 A+, 2794313 A+, 2794347 A+, 2794378 A+, 2794413 A+, 2794415 A+, 2794450 A+, 2794456 A+, 2794457 A+, 2794477 A+, 2794490 A+, 2794571 A+, 2794573 A+, 2794585 A+, 2794590 A+, 2794637 A+, 2794659 A+, 2794662 A+, 2794680 A+, 2794690 A+, 2794713 A+, 2794754 A+, 2794759 A+, 2794774 A+, 2794811 A+, 2794850 A+, 2794855 A+, 2794858 A+, 2794872 A+, 2794877 A+, 392693 A+, 392710 A+, 392916 A+, 439954 A+, 657643 A+, 672657 A+, 697166 A+, 725003 A+, 725443 A+, 725666 A+, 731312 A+, 732791 A+, 738026 A+, 940236 A+, 995685 A+, 1026716 A++, 1026720 A++, 1026741 A++, 1026754 A++, 1026756 A++, 1026768 A++, 1026772 A++, 1026783 A++, 1026796 A++, 1026824 A++, 1026829 A++, 1026841 A++, 1026847 A++, 1026860 A++, 1026879 A++, 1026881 A++, 1026885 A++, 1026888 A++, 1026902 A++, 1026904 A++, 1026907 A++, 1026912 A++, 1026913 A++, 1026922 A++, 1026928 A++, 1026938 A++, 1026941 A++, 1026943 A++, 1026965 A++, 1026973 A++, 1027003 A++, 1027020 A++, 1027061 A++, 1027079 A++, 1027099 A++, 1027100 A++, 1732657 A++, 1733098 A++, 1733365 A++, 1738980 A++, 1739030 A++, 1739043 A++, 1739045 A++, 1739046 A++, 1739047 A++, 1739056 A++, 1739126 A++, 1739134 A++, 1739141 A++, 1739155 A++, 1739157 A++, 1739160 A++, 1739170 A++, 1739182 A++, 1739196 A++, 1739207 A++, 1739210 A++, 1739211 A++, 1739218 A++, 1739225 A++, 1739271 A++, 1739391 A++, 2130991 A++, 2140658 A++, 2229595 A++, 2253753 A++, 2256941 A++, 2256950 A++, 2256961 A++, 2256970 A++, 2256971 A++, 2257002 A++, 2257013 A++, 2257018 A++, 2257025 A++, 2257037 A++, 2257039 A++, 2257044 A++, 2257048 A++, 2257064 A++, 2257074 A++, 2257076 A++, 2257091 A++, 2257095 A++, 2257104 A++, 2257117 A++, 2257118 A++, 2257121 A++, 2257129 A++, 2257134 A++, 2257135 A++, 2257141 A++, 2257147 A++, 2257161 A++, 2257163 A++, 2257164 A++, 2257178 A++, 2257190 A++, 2257193 A++, 2257202 A++, 2257204 A++, 2257209 A++, 2257225 A++, 2257235 A++, 2257251 A++, 2257259 A++, 2257280 A++, 2257298 A++, 2257331 A++, 2257350 A++, 2257353 A++, 2257376 A++, 2257384 A++, 2257385 A++, 2257416 A++, 2259608 A++, 2409625 A++, 2485846 A++, 2506288 A++, 2681658 A++, 2735726 A++, 2739340 A++, 2765919 A++, 2789312 A++, 2794361 A++, 2794414 A++, 2794418 A++, 2794428 A++, 2794460 A++, 2794470 A++, 2794475 A++, 2794519 A++, 2794533 A++, 2794595 A++, 2794698 A++, 2794810 A++, 392682 A++, 392691 A++, 657845 A++, 658029 A++, 658135 A++, 658166 A++, 658700 A++, 671370 A++, 671882 A++, 672008 A++, 672043 A++, 672291 A++, 672327 A++, 673620 A++, 674694 A++, 676868 A++, 690388 A++, 724383 A++, 724564 A++, 738030 A++, 989689 A++, 997972 A++, 1026723 A++, 1026765 A++, 1026790 A++, 1026805 A++, 1026833 A++, 1026864 A++, 1026865 A++, 1026869 A++, 1026875 A++, 1026906 A++, 1026917 A++, 1026952 A++, 1026962 A++, 1026970 A++, 1026996 A++, 1027029 A++, 1027038 A++, 1027054 A++, 1027119 A++, 1047123 A++, 1640343 A++, 1663658 A++, 1731774 A++, 1733393 A++, 1739108 A++, 1739142 A++, 1739235 A++, 1739242 A++, 1739477 A++, 1739544 A++, 1739599 A++, 2127637 A++, 2256931 A++, 2256969 A++, 2257017 A++, 2257024 A++, 2257026 A++, 2257041 A++, 2257050 A++, 2257065 A++, 2257088 A++, 2257115 A++, 2257125 A++, 2257126 A++, 2257133 A++, 2257146 A++, 2257148 A++, 2257158 A++, 2257159 A++, 2257250 A++, 2257256 A++, 2257351 A++, 2259595 A++, 2506230 A++, 2671315 A++, 2753166 A++, 2789048 A++, 2789689 A++, 2794424 A++, 2794446 A++, 2794448 A++, 2794588 A++, 2794700 A++, 2794763 A++, 392695 A++, 392702 A++, 657981 A++, 659387 A++, 659946 A++, 671993 A++, 672013 A++, 675654 A++, 691058 A++, 696288 A++, 797024 A++, 1026640 A+++, 1026673 A+++, 1026698 A+++, 1026809 A+++, 1026850 A+++, 1027017 A+++, 1027089 A+++, 1027104 A+++, 392687 A+++, 953167 A+++, 1026831 A++++, 1026957 A++++
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
strain ANN023
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Manually annotated by BRENDA team
mutant derivative of strain BW25113 from which the nuo operon is deleted by genomic replacement
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Manually annotated by BRENDA team
GR19N
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Manually annotated by BRENDA team
strain GV102
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Manually annotated by BRENDA team
strain MWC215
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Manually annotated by BRENDA team
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
Mus musculus C57/Bl
C57/Bl mice
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Manually annotated by BRENDA team
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1026715 A+, 1026734 A+, 1026871 A+, 1027001 A+, 1027052 A+, 1027059 A+, 1027064 A+, 1027085 A+, 1027088 A+, 1027103 A+, 1027130 A+, 1027135 A+, 1041160 A+, 1063031 A+, 1085602 A+, 1137685 A+, 1151975 A+, 1157568 A+, 1201663 A+, 1245007 A+, 1337257 A+, 1347031 A+, 1376031 A+, 1376171 A+, 1642777 A+, 1659524 A+, 1683343 A+, 1683516 A+, 1692855 A+, 1735930 A+, 1735936 A+, 1739004 A+, 1739021 A+, 1739130 A+, 1739152 A+, 1739167 A+, 1739184 A+, 1739290 A+, 1739313 A+, 1739324 A+, 1739361 A+, 1739376 A+, 1739389 A+, 1739393 A+, 1739395 A+, 1739430 A+, 1739495 A+, 1739541 A+, 1739550 A+, 1739585 A+, 1739586 A+, 1739588 A+, 1739592 A+, 2257152 A+, 2257284 A+, 2257296 A+, 2257357 A+, 2257386 A+, 2257410 A+, 2272050 A+, 2285922 A+, 2440776 A+, 2518578 A+, 2518976 A+, 2555782 A+, 2748999 A+, 2778694 A+, 2794321 A+, 2794371 A+, 2794471 A+, 2794492 A+, 2794526 A+, 2794598 A+, 2794615 A+, 2794634 A+, 2794671 A+, 2794675 A+, 2794682 A+, 2794697 A+, 2794821 A+, 2794837 A+, 2794839 A+, 2794846 A+, 2794870 A+, 788323 A+, 1026878 A++, 1026972 A++, 1049825 A++, 1157561 A++, 1367622 A++, 1533743 A++, 1739091 A++, 1739211 A++, 1739323 A++, 2257088 A++, 2257124 A++, 2485846 A++, 2794516 A++, 2794616 A++, 1157534 A++, 1576488 A++, 1687343 A++, 1733098 A++, 1739119 A++, 1739134 A++, 1739161 A++, 1739209 A++, 1739244 A++, 1739381 A++, 1739454 A++, 1739471 A++, 1739583 A++, 1739587 A++, 1739590 A++, 1739618 A++, 2127637 A++, 2131015 A++, 2257018 A++, 2257030 A++, 2257052 A++, 2257256 A++, 2257275 A++, 2257307 A++, 2257318 A++, 2257348 A++, 2257374 A++, 2794401 A++, 2794438 A++, 2794459 A++, 2794474 A++, 2794507 A++, 2794534 A++, 2794686 A++, 2794698 A++, 690388 A++, 694393 A++, 1026895 A+++, 1027004 A+++, 1027044 A+++, 1027074 A+++, 1027094 A+++, 1027111 A+++
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Automatic Mining of ENzyme DAta
Mycobacterium tuberculosis H37RV (ATCC 25618)
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Manually annotated by BRENDA team
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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1026628 A+, 1026657 A+, 1026674 A+, 1026683 A+, 1026688 A+, 1026690 A+, 1026694 A+, 1026701 A+, 1026725 A+, 1026849 A+, 1026852 A+, 1026976 A+, 1026978 A+, 1026979 A+, 1026980 A+, 1027010 A+, 1027032 A+, 1027048 A+, 1027072 A+, 1027084 A+, 1027098 A+, 1027107 A+, 1027146 A+, 1027149 A+, 1031007 A+, 1064403 A+, 1333698 A+, 1376025 A+, 1519128 A+, 1637587 A+, 1642362 A+, 1642913 A+, 1661869 A+, 1683343 A+, 1693532 A+, 1705192 A+, 1720362 A+, 1732856 A+, 1733692 A+, 1738968 A+, 1739008 A+, 1739015 A+, 1739020 A+, 1739038 A+, 1739041 A+, 1739060 A+, 1739063 A+, 1739109 A+, 1739140 A+, 1739162 A+, 1739178 A+, 1739205 A+, 1739224 A+, 1739292 A+, 1739309 A+, 1739338 A+, 1739395 A+, 1739409 A+, 1739410 A+, 1739422 A+, 1739466 A+, 1739620 A+, 1739637 A+, 2225799 A+, 2256907 A+, 2256913 A+, 2256916 A+, 2256917 A+, 2256967 A+, 2256984 A+, 2257027 A+, 2257058 A+, 2257093 A+, 2257136 A+, 2257142 A+, 2257183 A+, 2257354 A+, 2409495 A+, 2409559 A+, 2497867 A+, 2761735 A+, 2789375 A+, 2789773 A+, 2794248 A+, 2794324 A+, 2794326 A+, 2794384 A+, 2794434 A+, 2794451 A+, 2794468 A+, 2794514 A+, 2794561 A+, 2794565 A+, 2794581 A+, 2794594 A+, 2794643 A+, 2794657 A+, 2794681 A+, 2794703 A+, 2794707 A+, 2794721 A+, 2794730 A+, 2794732 A+, 2794759 A+, 2794794 A+, 2794798 A+, 2794825 A+, 2794831 A+, 392694 A+, 392832 A+, 738077 A+, 981319 A+, 1021413 A++, 1026824 A++, 1026888 A++, 1047123 A++, 1391476 A++, 1408609 A++, 1576902 A++, 1616174 A++, 1638692 A++, 1733365 A++, 1733393 A++, 1738980 A++, 1739055 A++, 1739072 A++, 1739074 A++, 1739221 A++, 1739225 A++, 1739271 A++, 1739381 A++, 1739397 A++, 1739426 A++, 2127637 A++, 2256886 A++, 2256931 A++, 2256969 A++, 2256975 A++, 2257037 A++, 2257045 A++, 2257046 A++, 2257068 A++, 2257075 A++, 2257080 A++, 2257085 A++, 2257094 A++, 2257121 A++, 2257161 A++, 2257163 A++, 2257346 A++, 2257372 A++, 2409625 A++, 2506230 A++, 2789048 A++, 2794291 A++, 2794327 A++, 2794336 A++, 2794365 A++, 2794370 A++, 2794383 A++, 2794419 A++, 2794448 A++, 2794475 A++, 2794536 A++, 2794551 A++, 2794553 A++, 657845 A++, 659387 A++, 659946 A++, 673505 A++, 691058 A++, 693745 A++, 694393 A++, 1026717 A++, 1026772 A++, 1026847 A++, 1026875 A++, 1026899 A++, 1026901 A++, 1026909 A++, 1026950 A++, 1027099 A++, 1638306 A++, 1733390 A++, 1739045 A++, 1739068 A++, 1739149 A++, 1739185 A++, 1739599 A++, 2257005 A++, 2257112 A++, 2257149 A++, 2274868 A++, 2794465 A++, 2794470 A++, 2794510 A++, 2794559 A++, 693720 A++, 695063 A++, 707375 A++, 997964 A++, 1026677 A+++, 1026685 A+++, 1026771 A+++, 1026773 A+++, 1026787 A+++, 1026862 A+++, 1026995 A+++, 1027047 A+++, 1027056 A+++, 1027071 A+++, 392693 A+++, 1026726 A++++, 1026783 A++++, 1026833 A++++, 1026835 A++++, 692231 A++++
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
shrimp
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
Vibrio cholerae ATCC 39541
subunit NqrB
UniProt
Manually annotated by BRENDA team
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
Vitis vinifera x Vitis vinifera
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Manually annotated by BRENDA team
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
GENERAL INFORMATION
ORGANISM
UNIPROT