Disease on EC 1.6.3.5 - renalase
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Acute Kidney Injury
Human renalase: a review of its biology, function, and implications for hypertension.
Acute Kidney Injury
Novel biomarkers of acute kidney injury following living donor liver transplantation.
Acute Kidney Injury
Renalase attenuates mitochondrial fission in cisplatin-induced acute kidney injury via modulating sirtuin-3.
Acute Kidney Injury
Renalase, a new secretory enzyme: Its role in hypertensive-ischemic cardiovascular diseases.
Acute Kidney Injury
Renalase, kidney and cardiovascular disease: Are they related or just coincidentally associated?
Acute Kidney Injury
Urinary renalase concentration in patients with preserved kidney function undergoing coronary angiography.
Adenocarcinoma
Inhibition of renalase expression and signaling has antitumor activity in pancreatic cancer.
Albuminuria
Despite similar reduction of blood pressure and renal ANG II and ET-1 levels aliskiren but not losartan normalizes albuminuria in hypertensive Ren-2 rats.
Albuminuria
Intervention with tranilast attenuates renal pathology and albuminuria in advanced experimental diabetic nephropathy.
Angina, Unstable
Association of Serum Renalase Levels and Renalase rs10887800 Polymorphism with Unstable Angina Pectoris Patients Having Metabolic Syndrome.
Aortic Coarctation
DNA synthesis in isolated arteries of normotensive and hypertensive rats: effects of the endothelium.
Aortic Coarctation
Low plasma renalase concentration in hypertensive patients after surgical repair of coarctation of aorta.
Aortic Valve Stenosis
Functional polymorphism of the renalase gene is associated with cardiac hypertrophy in female patients with aortic stenosis.
Atherosclerosis
Association of Imaging Classification of Intracranial Cerebral Atherosclerotic Vascular Stenosis in Ischemic Stroke and Renalase Gene Polymorphisms.
Atherosclerosis
Plasma Renalase is Not Associated with Blood Pressure and Brachial-Ankle Pulse Wave Velocity in Chinese Adults With Normal Renal Function.
Atherosclerosis
Valsartan Promoting Atherosclerotic Plaque Stabilization by Upregulating Renalase: A Potential-Related Gene of Atherosclerosis.
Atrial Fibrillation
Renalase is associated with adverse left atrial remodelling and disease burden in patients with atrial fibrillation undergoing pulmonary vein isolation.
Cardio-Renal Syndrome
Kidney Response to Chemotherapy-Induced Heart Failure: mRNA Analysis in Normotensive and Ren-2 Transgenic Hypertensive Rats.
Cardio-Renal Syndrome
Renalase attenuates hypertension, renal injury and cardiac remodelling in rats with subtotal nephrectomy.
Cardiomegaly
A functional polymorphism in renalase (Glu37Asp) is associated with cardiac hypertrophy, dysfunction, and ischemia: data from the heart and soul study.
Cardiomegaly
Castration has antihypertensive and organoprotective effects in male but not in female heterozygous Ren-2 rats.
Cardiomegaly
Effects of sodium restriction and cyclooxygenase-2 inhibition on the course of hypertension, proteinuria and cardiac hypertrophy in Ren-2 transgenic rats.
Cardiomegaly
Functional polymorphism of the renalase gene is associated with cardiac hypertrophy in female patients with aortic stenosis.
Cardiomegaly
Human renalase: a review of its biology, function, and implications for hypertension.
Cardiomegaly
Inhibition of Angiotensin-Converting Enzyme 2 Exacerbates Cardiac Hypertrophy and Fibrosis in Ren-2 Hypertensive Rats.
Cardiomegaly
Late-onset endothelin-A receptor blockade reduces podocyte injury in homozygous Ren-2 rats despite severe hypertension.
Cardiomegaly
Novel insights into the physiology of renalase and its role in hypertension and heart disease.
Cardiomegaly
Reduction of cardiac hypertrophy in TGR(mREN2)27 by angiotensin II receptor blockade.
Cardiomegaly
The partnership between renalase and ejection fraction as a risk factor for increased cardiac remodeling biomarkers in chronic heart failure patients.
Cardiomegaly
Unchanged sarcoplasmic reticulum Ca2+-ATPase activity, reduced Ca2+ sensitivity, and negative force-frequency relationship in transgenic rats overexpressing the mouse renin gene.
Cardiovascular Diseases
Age influence on renalase and catecholamines concentration in hypertensive patients, including maintained dialysis.
Cardiovascular Diseases
Associations between renalase concentration and the occurrence of selected diseases.
Cardiovascular Diseases
Increased serum renalase in peritoneal dialysis patients: Is it related to cardiovascular disease risk?
Cardiovascular Diseases
Is renalase a novel player in catecholaminergic signaling? The mystery of the catalytic activity of an intriguing new flavoenzyme.
Cardiovascular Diseases
Relationship between renalase and N-terminal pro-B-type natriuretic peptide (NT pro-BNP) in haemodialysis patients.
Cardiovascular Diseases
Renalase - new marker or just bystander in cardiovascular disease-clinical and experimental data.
Cardiovascular Diseases
Renalase deficiency in chronic kidney disease, and its contribution to hypertension and cardiovascular disease.
Cardiovascular Diseases
Renalase, a new secretory enzyme: Its role in hypertensive-ischemic cardiovascular diseases.
Cardiovascular Diseases
Renalase, kidney and cardiovascular disease: Are they related or just coincidentally associated?
Cardiovascular Diseases
Roles and mechanisms of renalase in cardiovascular disease: A promising therapeutic target.
Cardiovascular Diseases
Serum-to-urine renalase ratio and renalase fractional excretion in healthy adults and chronic kidney disease patients.
Cardiovascular Diseases
The Effect of Bilateral Nephrectomy on Renalase and Catecholamines in Hemodialysis Patients.
Coronary Artery Disease
A functional polymorphism in renalase (Glu37Asp) is associated with cardiac hypertrophy, dysfunction, and ischemia: data from the heart and soul study.
Coronary Artery Disease
Age influence on renalase and catecholamines concentration in hypertensive patients, including maintained dialysis.
Coronary Artery Disease
Atorvastatin and losartan may upregulate renalase activity in hypertension but not coronary artery diseases: The role of gene polymorphism.
Coronary Artery Disease
Circulating renalase, catecholamines, and vascular adhesion protein 1 in hypertensive patients.
Coronary Artery Disease
Correlation between plasma renalase level and coronary artery disease.
Coronary Artery Disease
Investigation of Renalase gene rs2576178 polymorphism in patients with coronary artery disease.
Coronary Artery Disease
Rs10887800 renalase gene polymorphism is associated with an increased risk of coronary artery disease in hemodialyzed patients.
Coronary Artery Disease
Synergistic effect of renalase and chronic kidney disease on endothelin-1 in patients with coronary artery disease ? a cross-sectional study.
Coronary Artery Disease
Urinary renalase concentration in patients with preserved kidney function undergoing coronary angiography.
Coronary Disease
Renalase gene polymorphism in patients with hypertension and concomitant coronary heart disease.
COVID-19
Decreased plasma levels of the survival factor renalase are associated with worse outcomes in COVID-19.
Diabetes Mellitus
Circulating renalase predicts all-cause mortality and renal outcomes in patients with advanced chronic kidney disease.
Diabetes Mellitus
Renal redox stress and remodeling in metabolic syndrome, type 2 diabetes mellitus, and diabetic nephropathy: paying homage to the podocyte.
Diabetes Mellitus
Renalase gene Glu37Asp polymorphism affects susceptibility to diabetic retinopathy in type 2 diabetes mellitus.
Diabetes Mellitus
Renalase might be associated with hypertension and insulin resistance in Type 2 diabetes.
Diabetes Mellitus
Renalase, a new secretory enzyme: Its role in hypertensive-ischemic cardiovascular diseases.
Diabetes Mellitus, Type 1
Evidence of Gene-Gene Interaction and Age-at-Diagnosis Effects in Type 1 Diabetes.
Diabetes Mellitus, Type 1
Renalase: its role as a cytokine, and an update on its association with type 1 diabetes and ischemic stroke.
Diabetes Mellitus, Type 2
Polymorphism of the renalase gene in gestational diabetes mellitus.
Diabetes Mellitus, Type 2
Renal redox stress and remodeling in metabolic syndrome, type 2 diabetes mellitus, and diabetic nephropathy: paying homage to the podocyte.
Diabetes Mellitus, Type 2
Renalase gene Glu37Asp polymorphism affects susceptibility to diabetic retinopathy in type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
Renalase gene polymorphisms in patients with type 2 diabetes, hypertension and stroke.
Diabetes Mellitus, Type 2
Renalase might be associated with hypertension and insulin resistance in Type 2 diabetes.
Diabetic Cardiomyopathies
FT011, a new anti-fibrotic drug, attenuates fibrosis and chronic heart failure in experimental diabetic cardiomyopathy.
Diabetic Cardiomyopathies
FT23, an orally active antifibrotic compound, attenuates structural and functional abnormalities in an experimental model of diabetic cardiomyopathy.
Diabetic Cardiomyopathies
Functional, structural and molecular aspects of diastolic heart failure in the diabetic (mRen-2)27 rat.
Diabetic Nephropathies
Effects of low-dose and early versus late perindopril treatment on the progression of severe diabetic nephropathy in (mREN-2)27 rats.
Diabetic Nephropathies
Perindopril attenuates tubular hypoxia and inflammation in an experimental model of diabetic nephropathy in transgenic Ren-2 rats.
Diabetic Nephropathies
Renal injury in streptozotocin-diabetic Ren2-transgenic rats is mainly dependent on hypertension, not on diabetes.
Diabetic Retinopathy
Renalase gene Glu37Asp polymorphism affects susceptibility to diabetic retinopathy in type 2 diabetes mellitus.
Diabetic Retinopathy
Valsartan but not atenolol improves vascular pathology in diabetic Ren-2 rat retina.
Essential Hypertension
Investigation of Renalase gene rs2576178 polymorphism in patients with coronary artery disease.
Essential Hypertension
Novel insights into the physiology of renalase and its role in hypertension and heart disease.
Essential Hypertension
Regulation of blood pressure and cardiovascular function by renalase.
Essential Hypertension
Renalase gene is a novel susceptibility gene for essential hypertension: a two-stage association study in northern Han Chinese population.
Essential Hypertension
Transcriptional regulation of the novel monoamine oxidase renalase: Crucial roles of transcription factors Sp1, STAT3, and ZBP89.
Fatty Liver
Renalase Attenuates Mouse Fatty Liver Ischemia/Reperfusion Injury through Mitigating Oxidative Stress and Mitochondrial Damage via Activating SIRT1.
Gastrointestinal Diseases
Renalase: A Multi-Functional Signaling Molecule with Roles in Gastrointestinal Disease.
Heart Diseases
An association study on renalase polymorphisms and ischemic stroke in a Chinese population.
Heart Diseases
Novel insights into the physiology of renalase and its role in hypertension and heart disease.
Heart Diseases
Roles and mechanisms of renalase in cardiovascular disease: A promising therapeutic target.
Heart Diseases
Tranilast attenuates cardiac matrix deposition in experimental diabetes: role of transforming growth factor-beta.
Heart Failure
Association of Plasma Renalase and Left Ventricle Mass Index in Heart Failure Patients Stratified to the Category of the Ejection Fraction: A Pilot Study.
Heart Failure
Deleterious Effects of Hyperactivity of the Renin-Angiotensin System and Hypertension on the Course of Chemotherapy-Induced Heart Failure after Doxorubicin Administration: A Study in Ren-2 Transgenic Rat.
Heart Failure
Effect of angiotensin-converting enzyme blockade, alone or combined with blockade of soluble epoxide hydrolase, on the course of congestive heart failure and occurrence of renal dysfunction in Ren-2 transgenic hypertensive rats with aorto-caval fistula.
Heart Failure
Effects of Epoxyeicosatrienoic Acid-Enhancing Therapy on the Course of Congestive Heart Failure in Angiotensin II-Dependent Rat Hypertension: From mRNA Analysis towards Functional In Vivo Evaluation.
Heart Failure
Epoxyeicosatrienoic Acid-Based Therapy Attenuates the Progression of Postischemic Heart Failure in Normotensive Sprague-Dawley but Not in Hypertensive Ren-2 Transgenic Rats.
Heart Failure
Inhibition of soluble epoxide hydrolase counteracts the development of renal dysfunction and progression of congestive heart failure in Ren-2 transgenic hypertensive rats with aorto-caval fistula.
Heart Failure
Kidney Response to Chemotherapy-Induced Heart Failure: mRNA Analysis in Normotensive and Ren-2 Transgenic Hypertensive Rats.
Heart Failure
Renal Sympathetic Denervation Attenuates Congestive Heart Failure in Angiotensin II-Dependent Hypertension: Studies with Ren-2 Transgenic Hypertensive Rats with Aortocaval Fistula.
Heart Failure
Renalase deficiency in heart failure model of rats--a potential mechanism underlying circulating norepinephrine accumulation.
Heart Failure
Renalase improves pressure overload-induced heart failure in rats by regulating extracellular signal-regulated protein kinase 1/2 signaling.
Heart Failure
Sex-linked differences in the course of chronic kidney disease and congestive heart failure: a study in 5/6 nephrectomized Ren-2 transgenic hypertensive rats with volume overload induced using aorto-caval fistula.
Heart Failure
Sex-linked differences in the mortality in Ren-2 transgenic hypertensive rats with aorto-caval fistula: effects of treatment with angiotensin converting enzyme alone and combined with inhibitor of soluble epoxide hydrolase.
Heart Failure
The Discriminatory Ability of Renalase and Biomarkers of Cardiac Remodeling for the Prediction of Ischemia in Chronic Heart Failure Patients With the Regard to the Ejection Fraction.
Heart Failure
The partnership between renalase and ejection fraction as a risk factor for increased cardiac remodeling biomarkers in chronic heart failure patients.
Heart Failure
Vasodilatory responses of renal interlobular arteries to epoxyeicosatrienoic acids analog are not enhanced in Ren-2 transgenic hypertensive rats: evidence against a role of direct vascular effects of epoxyeicosatrienoic acids in progression of experimental heart failure.
Hypertension
Abolition of hypertension-induced end-organ damage by androgen receptor blockade in transgenic rats harboring the mouse ren-2 gene.
Hypertension
Alterations in coronary artery vascular reactivity of hypertensive Ren-2 transgenic rats.
Hypertension
Altered Renal Vascular Responsiveness to Vasoactive Agents in Rats with Angiotensin II-Dependent Hypertension and Congestive Heart Failure.
Hypertension
An association study on renalase polymorphisms and ischemic stroke in a Chinese population.
Hypertension
Angiotensin II receptor blockade in TGR(mREN2)27: effects of renin-angiotensin-system gene expression and cardiovascular functions.
Hypertension
Angiotensin peptides acting at rostral ventrolateral medulla contribute to hypertension of TGR(mREN2)27 rats.
Hypertension
Antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats is mediated by suppression of the intrarenal renin-angiotensin system.
Hypertension
Association of Imaging Classification of Intracranial Cerebral Atherosclerotic Vascular Stenosis in Ischemic Stroke and Renalase Gene Polymorphisms.
Hypertension
Association of Renalase SNPs rs2296545 and rs2576178 with the Risk of Hypertension: A Meta-Analysis.
Hypertension
AT1 receptor antisense therapy transiently lowers blood pressure in Ren-2 transgenic rats.
Hypertension
Atorvastatin and losartan may upregulate renalase activity in hypertension but not coronary artery diseases: The role of gene polymorphism.
Hypertension
Basal and Activated Calcium Sensitization Mediated by RhoA/Rho Kinase Pathway in Rats with Genetic and Salt Hypertension.
Hypertension
Blockade of endothelin receptors attenuates end-organ damage in homozygous hypertensive ren-2 transgenic rats.
Hypertension
Cardiorenal protective effects of vasopeptidase inhibition with omapatrilat in hypertensive transgenic (mREN-2)27 rats.
Hypertension
Cardiovascular end-organ damage in Ren-2 transgenic rats compared to spontaneously hypertensive rats.
Hypertension
Changes of blood pressure and aortic strip contractile responses to ET-1 of heterozygous female transgenic rats, TGR(mRen2)27.
Hypertension
Chronic dexamethasone treatment suppresses hypertension development in the transgenic rat TGR(mREN2)27.
Hypertension
Chronic endothelin receptor blockade reduces end-organ damage independently of blood pressure effects in salt-loaded heterozygous Ren-2 transgenic rats.
Hypertension
Circadian rhythms in renal function in hypertensive TGR(mRen-2)27 rats and their normotensive controls.
Hypertension
Circulating renalase, catecholamines, and vascular adhesion protein 1 in hypertensive patients.
Hypertension
Combined inhibition of 20-hydroxyeicosatetraenoic acid formation and of epoxyeicosatrienoic acids degradation attenuates hypertension and hypertension-induced end-organ damage in Ren-2 transgenic rats.
Hypertension
Combined suppression of the intrarenal and circulating vasoconstrictor renin-ACE-ANG II axis and augmentation of the vasodilator ACE2-ANG 1-7-Mas axis attenuates the systemic hypertension in Ren-2 transgenic rats exposed to chronic hypoxia.
Hypertension
Deleterious Effects of Hyperactivity of the Renin-Angiotensin System and Hypertension on the Course of Chemotherapy-Induced Heart Failure after Doxorubicin Administration: A Study in Ren-2 Transgenic Rat.
Hypertension
Differential gene expression of renin and angiotensinogen in the TGR(mREN-2)27 transgenic rat.
Hypertension
Dissociation of blood pressure reduction from end-organ damage in TGR(mREN2)27 transgenic hypertensive rats.
Hypertension
Effect of angiotensin II blockade on a new congenic model of hypertension derived from transgenic Ren-2 rats.
Hypertension
Effects of anesthesia on plasma and kidney ANG II levels in normotensive and ANG II-dependent hypertensive rats.
Hypertension
Effects of angiotensin-converting enzyme inhibitor and angiotensin type 1 receptor antagonist in deoxycorticosterone acetate-salt hypertensive mice lacking Ren-2 gene.
Hypertension
Effects of changes in sodium balance on plasma and kidney angiotensin II levels in anesthetized and conscious Ren-2 transgenic rats.
Hypertension
Effects of chronic cytochrome P-450 inhibition on the course of hypertension and end-organ damage in Ren-2 transgenic rats.
Hypertension
Effects of combined endothelin a receptor and renin-angiotensin system blockade on the course of end-organ damage in 5/6 nephrectomized Ren-2 hypertensive rats.
Hypertension
Effects of dietary salt load and salt depletion on the course of hypertension and angiotensin II levels in male and female heterozygous Ren-2 transgenic rats.
Hypertension
Effects of Epoxyeicosatrienoic Acid-Enhancing Therapy on the Course of Congestive Heart Failure in Angiotensin II-Dependent Rat Hypertension: From mRNA Analysis towards Functional In Vivo Evaluation.
Hypertension
Effects of salt intake and potassium supplementation on renalase expression in the kidneys of Dahl salt-sensitive rats.
Hypertension
Effects of sodium restriction and cyclooxygenase-2 inhibition on the course of hypertension, proteinuria and cardiac hypertrophy in Ren-2 transgenic rats.
Hypertension
Enalapril and pressure-diuresis in hypertensive rats transgenic for mouse renin gene.
Hypertension
End-organ damage in hypertensive transgenic Ren-2 rats: influence of early and late endothelin receptor blockade.
Hypertension
Endothelial dysfunction in the aorta of transgenic rats harboring the mouse Ren-2 gene.
Hypertension
Endothelial vasoconstrictor prostanoids modulate contractions to acetylcholine and ANG II in Ren-2 rats.
Hypertension
Endothelin receptor blockade does not affect blood pressure or angiotensin II levels in CYP1A1-Ren-2 transgenic rats with acutely induced hypertension.
Hypertension
Epoxyeicosatrienoic Acid-Based Therapy Attenuates the Progression of Postischemic Heart Failure in Normotensive Sprague-Dawley but Not in Hypertensive Ren-2 Transgenic Rats.
Hypertension
Estrogen augments the contribution of nitric oxide to blood pressure regulation in transgenic hypertensive rats expressing the mouse Ren-2 gene.
Hypertension
Exercise training prevents development of cardiac contractile dysfunction in hypertensive TG (mREN-2)27 rats.
Hypertension
FT011, a Novel Cardiorenal Protective Drug, Reduces Inflammation, Gliosis and Vascular Injury in Rats with Diabetic Retinopathy.
Hypertension
Glomerular expression of the ATP-sensitive P2X receptor in diabetic and hypertensive rat models.
Hypertension
High-performance Liquid Chromatography Measured Metabolites of Endogenous Catecholamines and Their Relations to Chronic Kidney Disease and High Blood Pressure in Heart Transplant Recipients.
Hypertension
Human renalase: a review of its biology, function, and implications for hypertension.
Hypertension
Hypertension and kidney disease: is renalase a new player or an innocent bystander?
Hypertension
Hypertension in the (mRen-2)27 rat is not explained by enhanced kinetics of transgenic Ren-2 renin.
Hypertension
Hypertension in the transgenic rat TGR(mRen-2)27 may be due to enhanced kinetics of the reaction between mouse renin and rat angiotensinogen.
Hypertension
Impact of renal denervation on renalase expression in adult rats with spontaneous hypertension.
Hypertension
Increased expression of angiotensin peptides in the brain of transgenic hypertensive rats.
Hypertension
Increased vascular angiotensin formation in female rats harboring the mouse Ren-2 gene.
Hypertension
Inhibition of soluble epoxide hydrolase counteracts the development of renal dysfunction and progression of congestive heart failure in Ren-2 transgenic hypertensive rats with aorto-caval fistula.
Hypertension
Inhibition of soluble epoxide hydrolase is renoprotective in 5/6 nephrectomized Ren-2 transgenic hypertensive rats.
Hypertension
Late-onset endothelin-A receptor blockade reduces podocyte injury in homozygous Ren-2 rats despite severe hypertension.
Hypertension
Long-term prevention of hypertension and end-organ damage in Ren-2 transgenic rats is achieved only with persistent but not transient AT1 receptor blockade.
Hypertension
Low plasma renalase concentration in hypertensive patients after surgical repair of coarctation of aorta.
Hypertension
Morphology and function of the adrenal zona glomerulosa of transgenic rats TGR [mREN2] 27: effects of prolonged sodium restriction.
Hypertension
Nifedipine-sensitive blood pressure component in hypertensive models characterized by high activity of either sympathetic nervous system or renin-angiotensin system.
Hypertension
Novel insights into the physiology of renalase and its role in hypertension and heart disease.
Hypertension
Omega-3 polyunsaturated fatty acid supplementation reduces hypertension in TGR(mRen-2)27 rats.
Hypertension
Ontogenetic regulation of mouse Ren-2d renin gene in transgenic hypertensive rats, TGR(mREN2)27.
Hypertension
Plasma renalase concentration before and after radiofrequency renal denervation in patients with resistant hypertension.
Hypertension
Plasma Renalase is Not Associated with Blood Pressure and Brachial-Ankle Pulse Wave Velocity in Chinese Adults With Normal Renal Function.
Hypertension
Polymorphism of the renalase gene in end-stage renal disease patients affected by hypertension.
Hypertension
Reduction of cardiac hypertrophy in TGR(mREN2)27 by angiotensin II receptor blockade.
Hypertension
Reduction of oxidative stress does not attenuate the development of angiotensin II-dependent hypertension in Ren-2 transgenic rats.
Hypertension
Regulation of renalase expression by D5 dopamine receptors in rat renal proximal tubule cells.
Hypertension
Relationship between Renalase Expression and Kidney Disease: an Observational Study in 72 Patients Undergoing Renal Biopsy.
Hypertension
Renal mechanisms contributing to the antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats with inducible hypertension.
Hypertension
Renal Sympathetic Denervation Attenuates Congestive Heart Failure in Angiotensin II-Dependent Hypertension: Studies with Ren-2 Transgenic Hypertensive Rats with Aortocaval Fistula.
Hypertension
Renalase - new marker or just bystander in cardiovascular disease-clinical and experimental data.
Hypertension
Renalase and hypertension-demographic and clinical correlates in obstructive sleep apnea.
Hypertension
Renalase Assessment With Regard to Kidney Function, Lipid Disturbances, and Endothelial Dysfunction Parameters in Stable Renal Transplant Recipients.
Hypertension
Renalase attenuates hypertension, renal injury and cardiac remodelling in rats with subtotal nephrectomy.
Hypertension
Renalase deficiency in chronic kidney disease, and its contribution to hypertension and cardiovascular disease.
Hypertension
Renalase gene polymorphism in patients with hypertension and concomitant coronary heart disease.
Hypertension
Renalase gene polymorphisms in patients with type 2 diabetes, hypertension and stroke.
Hypertension
Renalase Gene rs2576178 Polymorphism in Hemodialysis Patients: Study in Bosnia and Herzegovina.
Hypertension
Renalase improves pressure overload-induced heart failure in rats by regulating extracellular signal-regulated protein kinase 1/2 signaling.
Hypertension
Renalase is Removed by Kidneys and During Dialysis - Excess Related to CKD Complications?
Hypertension
Renalase might be associated with hypertension and insulin resistance in Type 2 diabetes.
Hypertension
Renalase mRNA levels in the brain, heart, and kidneys of spontaneously hypertensive rats with moderate and high hypertension.
Hypertension
Renalase rs10887800 polymorphism is associated with severe pre-eclampsia in southeast Iranian women.
Hypertension
Renalase, a new secretory enzyme: Its role in hypertensive-ischemic cardiovascular diseases.
Hypertension
Renalase, a Novel Enzyme Involved in Blood Pressure Regulation, Is Related to Kidney Function but Not to Blood Pressure in Hemodialysis Patients.
Hypertension
Renalase, Catecholamine and Nitric Oxide Changes Before and After Sodium Nitroprusside Administration to Patients who Develop Post-Coronary Artery By-Pass (CABG) Hypertension.
Hypertension
Renalase, kidney and cardiovascular disease: Are they related or just coincidentally associated?
Hypertension
Role of nNOS in regulation of renal function in hypertensive Ren-2 transgenic rats.
Hypertension
Role of renalase in the regulation of blood pressure and the renal dopamine system.
Hypertension
Roles of AT1 and AT2 receptors in the hypertensive Ren-2 gene transgenic rat kidney.
Hypertension
Roles of nitric oxide and oxidative stress in the regulation of blood pressure and renal function in prehypertensive Ren-2 transgenic rats.
Hypertension
Serum-to-urine renalase ratio and renalase fractional excretion in healthy adults and chronic kidney disease patients.
Hypertension
Sex-linked differences in the course of chronic kidney disease and congestive heart failure: a study in 5/6 nephrectomized Ren-2 transgenic hypertensive rats with volume overload induced using aorto-caval fistula.
Hypertension
Similar renoprotection after renin-angiotensin-dependent and -independent antihypertensive therapy in 5/6-nephrectomized Ren-2 transgenic rats: are there blood pressure-independents effects?
Hypertension
Sodium-dependent modulation of systemic and urinary renalase expression and activity in the rat remnant kidney.
Hypertension
Spontaneous development of malignant phase hypertension in transgenic Ren-2 rats.
Hypertension
Synthesis of human renalase1 in Escherichia coli and its purification as a FAD-containing holoprotein.
Hypertension
The absence of sympathoexcitation during the development of hypertension in Cyp1a1 Ren-2 transgenic rats.
Hypertension
The association study on renalase polymorphism and hypertension: a meta-analysis.
Hypertension
The Effect of Bilateral Nephrectomy on Renalase and Catecholamines in Hemodialysis Patients.
Hypertension
The effects of repeated delivery of angiotensin II AT(1) receptor antisense on distinct vasoactive systems in Ren-2 transgenic rats: young vs. adult animals.
Hypertension
The hypertensive Ren-2 transgenic rat TGR (mREN2)27 in hypertension research. Characteristics and functional aspects.
Hypertension
The Relationship between Sleep Bruxism Intensity and Renalase Concentration-An Enzyme Involved in Hypertension Development.
Hypertension
The Renalase Asp37Glu polymorphism is not associated with hypertension and cardiovascular events in an urban-based prospective cohort: the Malmö Diet and cancer study.
Hypertension
The role of intrarenal angiotensin II in the development of hypertension in Ren-2 transgenic rats.
Hypertension
The role of urinary renalase on early-stage renal damage in Chinese adults with primary hypertension.
Hypertension
Therapeutic perspectives in hypertension: novel means for renin-angiotensin-aldosterone system modulation and emerging device-based approaches.
Hypertension
Transgenic rats carrying the mouse renin gene--morphological characterization of a low-renin hypertension model.
Hypertension
Transgenic rats: tools to study the function of the renin-angiotensin system.
Hypertension
Two pharmacological epoxyeicosatrienoic acid-enhancing therapies are effectively antihypertensive and reduce the severity of ischemic arrhythmias in rats with angiotensin II-dependent hypertension.
Hypertension
Zona glomerulosa of the adrenal gland in a transgenic strain of rat: a morphologic and functional study.
Hypertension
Zonal distribution and regulation of adrenal renin in a transgenic model of hypertension in the rat.
Hypertension
[Morphological characteristic of renal injury in hypertensive rat strain transgenic for the mouse Ren-2 renin gene (TGR [mRen2] 27]
Hypertension
[Renalase and its role in the development of hypertension in patients with chronic renal failure].
Hypertension, Malignant
Endothelin receptor blockade does not affect blood pressure or angiotensin II levels in CYP1A1-Ren-2 transgenic rats with acutely induced hypertension.
Hypertension, Malignant
Renal mechanisms contributing to the antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats with inducible hypertension.
Hypertension, Pulmonary
Intrapulmonary activation of the angiotensin-converting enzyme type 2/angiotensin 1-7/G-protein-coupled Mas receptor axis attenuates pulmonary hypertension in Ren-2 transgenic rats exposed to chronic hypoxia.
Hypertrophy, Left Ventricular
Functional polymorphism of the renalase gene is associated with cardiac hypertrophy in female patients with aortic stenosis.
Hypotension
Online Haemodiafiltration Improves Inflammatory State in Dialysis Patients: A Longitudinal Study.
Infertility
Single nucleotide polymorphisms in Renalase and KCNQ1 genes and female infertility: A cross-sectional study in Pakistan.
Infertility, Female
Associations between renalase concentration and the occurrence of selected diseases.
Infertility, Female
Single nucleotide polymorphisms in Renalase and KCNQ1 genes and female infertility: A cross-sectional study in Pakistan.
Insulin Resistance
Abrogation of oxidative stress improves insulin sensitivity in the Ren-2 rat model of tissue angiotensin II overexpression.
Insulin Resistance
Renalase might be associated with hypertension and insulin resistance in Type 2 diabetes.
Ischemic Stroke
An association study on renalase polymorphisms and ischemic stroke in a Chinese population.
Ischemic Stroke
Association of Imaging Classification of Intracranial Cerebral Atherosclerotic Vascular Stenosis in Ischemic Stroke and Renalase Gene Polymorphisms.
Ischemic Stroke
Associations between renalase concentration and the occurrence of selected diseases.
Ischemic Stroke
Investigation of Renalase gene rs2576178 polymorphism in patients with coronary artery disease.
Ischemic Stroke
Renalase, a new secretory enzyme: Its role in hypertensive-ischemic cardiovascular diseases.
Ischemic Stroke
Renalase: its role as a cytokine, and an update on its association with type 1 diabetes and ischemic stroke.
Kidney Diseases
A new method for quantitative determination of renalase based on mass spectrometric determination of a proteotypic peptide labelled with stable isotopes.
Kidney Diseases
Associations between renalase concentration and the occurrence of selected diseases.
Kidney Diseases
Hypertension and kidney disease: is renalase a new player or an innocent bystander?
Kidney Diseases
Is renalase a novel player in catecholaminergic signaling? The mystery of the catalytic activity of an intriguing new flavoenzyme.
Kidney Diseases
Relationship between Renalase Expression and Kidney Disease: an Observational Study in 72 Patients Undergoing Renal Biopsy.
Kidney Diseases
Renalase, a Novel Enzyme Involved in Blood Pressure Regulation, Is Related to Kidney Function but Not to Blood Pressure in Hemodialysis Patients.
Kidney Failure, Chronic
Human renalase: a review of its biology, function, and implications for hypertension.
Kidney Failure, Chronic
Identification, expression and tissue distribution of a renalase homologue from mouse.
Kidney Failure, Chronic
Investigation of Renalase gene rs2576178 polymorphism in patients with coronary artery disease.
Kidney Failure, Chronic
Plasma and urine renalase levels and activity during the recovery of renal function in kidney transplant recipients.
Kidney Failure, Chronic
Plasma renalase in chronic kidney disease: differences and similarities between humans and rats.
Kidney Failure, Chronic
Polymorphism of the renalase gene in end-stage renal disease patients affected by hypertension.
Kidney Failure, Chronic
Regulation of blood pressure and cardiovascular function by renalase.
Kidney Failure, Chronic
Relationship between renalase and N-terminal pro-B-type natriuretic peptide (NT pro-BNP) in haemodialysis patients.
Kidney Failure, Chronic
Renalase deficiency in chronic kidney disease, and its contribution to hypertension and cardiovascular disease.
Kidney Failure, Chronic
Renalase gene polymorphism and epinephrine level in chronic kidney disease.
Kidney Failure, Chronic
Renalase is a novel renal hormone that regulates cardiovascular function.
Kidney Failure, Chronic
Renalase is a novel, soluble monoamine oxidase that regulates cardiac function and blood pressure.
Kidney Failure, Chronic
Renalase Secreted by Human Kidney HEK293T Cells Lacks its N-Terminal Peptide: Implications for Putative Mechanisms of Renalase Action.
Kidney Failure, Chronic
Rs10887800 renalase gene polymorphism is associated with an increased risk of coronary artery disease in hemodialyzed patients.
Liver Cirrhosis
Effects of renalase deficiency on liver fibrosis markers in a nonalcoholic steatohepatitis mouse model.
Melanoma
Renalase Expression by Melanoma and Tumor-Associated Macrophages Promotes Tumor Growth through a STAT3-Mediated Mechanism.
Metabolic Diseases
Post-Transcriptional Regulation of Renalase Gene by miR-29 and miR-146 MicroRNAs: Implications for Cardiometabolic Disorders.
Metabolic Syndrome
Association of Serum Renalase Levels and Renalase rs10887800 Polymorphism with Unstable Angina Pectoris Patients Having Metabolic Syndrome.
Muscular Atrophy
Denervation-induced muscle atrophy suppression in renalase-deficient mice via increased protein synthesis.
Myocardial Infarction
Serum Renalase Levels Are Predicted by Brain-Derived Neurotrophic Factor and Associated with Cardiovascular Events and Mortality after Percutaneous Coronary Intervention.
Myocardial Ischemia
Renalase protects the cardiomyocytes of Sprague-Dawley rats against ischemia and reperfusion injury by reducing myocardial cell necrosis and apoptosis.
Myocardial Ischemia
Renalase, a new secretory enzyme: Its role in hypertensive-ischemic cardiovascular diseases.
Neoplasms
Elevated renalase levels in patients with acute coronary microvascular dysfunction - A possible biomarker for ischemia.
Neoplasms
Inhibition of renalase expression and signaling has antitumor activity in pancreatic cancer.
Neoplasms
Renalase Expression by Melanoma and Tumor-Associated Macrophages Promotes Tumor Growth through a STAT3-Mediated Mechanism.
Neoplasms
The Renalase Asp37Glu polymorphism is not associated with hypertension and cardiovascular events in an urban-based prospective cohort: the Malmö Diet and cancer study.
Nephritis
Relationship between Renalase Expression and Kidney Disease: an Observational Study in 72 Patients Undergoing Renal Biopsy.
Nephrosclerosis
Angiotensin II formation in the kidney and nephrosclerosis in Ren-2 hypertensive rats.
Nephrotic Syndrome
Relationship between Renalase Expression and Kidney Disease: an Observational Study in 72 Patients Undergoing Renal Biopsy.
Non-alcoholic Fatty Liver Disease
Effects of renalase deficiency on liver fibrosis markers in a nonalcoholic steatohepatitis mouse model.
Obesity
Elevated renalase levels in patients with acute coronary microvascular dysfunction - A possible biomarker for ischemia.
Pancreatic Neoplasms
Inhibition of renalase expression and signaling has antitumor activity in pancreatic cancer.
Paraganglioma
Can cerebellin and renalase measurements contribute to the elimination of false positive results in pheochromocytoma and paraganglioma diagnoses?
Pheochromocytoma
Can cerebellin and renalase measurements contribute to the elimination of false positive results in pheochromocytoma and paraganglioma diagnoses?
Polycystic Ovary Syndrome
Single nucleotide polymorphisms in Renalase and KCNQ1 genes and female infertility: A cross-sectional study in Pakistan.
Pre-Eclampsia
Renalase gene polymorphism is associated with increased blood pressure in preeclampsia.
Pre-Eclampsia
Renalase rs10887800 polymorphism is associated with severe pre-eclampsia in southeast Iranian women.
Pre-Eclampsia
Serum anti mullerian hormone and renalase levels in predicting the risk of preeclampsia.
Proteinuria
Castration has antihypertensive and organoprotective effects in male but not in female heterozygous Ren-2 rats.
Proteinuria
Effects of Renin-Angiotensin System Inhibitors on Renal Expression of Renalase in Sprague-Dawley Rats Fed With High Salt Diet.
Proteinuria
Effects of sodium restriction and cyclooxygenase-2 inhibition on the course of hypertension, proteinuria and cardiac hypertrophy in Ren-2 transgenic rats.
Proteinuria
Late-onset endothelin-A receptor blockade reduces podocyte injury in homozygous Ren-2 rats despite severe hypertension.
Proteinuria
Persistent antihypertensive effect of aliskiren is accompanied by reduced proteinuria and normalization of glomerular area in Ren-2 transgenic rats.
Proteinuria
Relationship between Renalase Expression and Kidney Disease: an Observational Study in 72 Patients Undergoing Renal Biopsy.
Proteinuria
Renoprotective effects of ET(A) receptor antagonists therapy in experimental non-diabetic chronic kidney disease: Is there still hope for the future?
Proteinuria
Role of the eNOS-NO System in Regulating the Antiproteinuric Effects of VEGF Receptor 2 Inhibition in Diabetes.
Proteinuria
Serum-to-urine renalase ratio and renalase fractional excretion in healthy adults and chronic kidney disease patients.
Renal Insufficiency
Relationship between Renalase Expression and Kidney Disease: an Observational Study in 72 Patients Undergoing Renal Biopsy.
Renal Insufficiency, Chronic
Addition of Endothelin A-Receptor Blockade Spoils the Beneficial Effect of Combined Renin-Angiotensin and Soluble Epoxide Hydrolase Inhibition: Studies on the Course of Chronic Kidney Disease in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats.
Renal Insufficiency, Chronic
Cardioprotective Effect of Renalase in 5/6 Nephrectomized Rats.
Renal Insufficiency, Chronic
Catecholamines regulate the activity, secretion, and synthesis of renalase.
Renal Insufficiency, Chronic
Chronic kidney disease is associated with increased levels of renalase in serum and decreased in erythrocytes.
Renal Insufficiency, Chronic
Circulating Levels of Renalase, Norepinephrine, and Dopamine in Dialysis Patients.
Renal Insufficiency, Chronic
Circulating renalase predicts all-cause mortality and renal outcomes in patients with advanced chronic kidney disease.
Renal Insufficiency, Chronic
Combined Inhibition of Soluble Epoxide Hydrolase and Renin-Angiotensin System Exhibits Superior Renoprotection to Renin-Angiotensin System Blockade in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats with Established Chronic Kidney Disease.
Renal Insufficiency, Chronic
High-performance Liquid Chromatography Measured Metabolites of Endogenous Catecholamines and Their Relations to Chronic Kidney Disease and High Blood Pressure in Heart Transplant Recipients.
Renal Insufficiency, Chronic
Human renalase: a review of its biology, function, and implications for hypertension.
Renal Insufficiency, Chronic
Increased serum renalase in peritoneal dialysis patients: Is it related to cardiovascular disease risk?
Renal Insufficiency, Chronic
Novel insights into the physiology of renalase and its role in hypertension and heart disease.
Renal Insufficiency, Chronic
Plasma renalase in chronic kidney disease: differences and similarities between humans and rats.
Renal Insufficiency, Chronic
Polymorphism of the renalase gene in end-stage renal disease patients affected by hypertension.
Renal Insufficiency, Chronic
Regulation of blood pressure and cardiovascular function by renalase.
Renal Insufficiency, Chronic
Relationship between renalase and N-terminal pro-B-type natriuretic peptide (NT pro-BNP) in haemodialysis patients.
Renal Insufficiency, Chronic
Renalase - new marker or just bystander in cardiovascular disease-clinical and experimental data.
Renal Insufficiency, Chronic
Renalase Assessment With Regard to Kidney Function, Lipid Disturbances, and Endothelial Dysfunction Parameters in Stable Renal Transplant Recipients.
Renal Insufficiency, Chronic
Renalase attenuates hypertension, renal injury and cardiac remodelling in rats with subtotal nephrectomy.
Renal Insufficiency, Chronic
Renalase deficiency in chronic kidney disease, and its contribution to hypertension and cardiovascular disease.
Renal Insufficiency, Chronic
Renalase gene polymorphism and epinephrine level in chronic kidney disease.
Renal Insufficiency, Chronic
Renalase in chronic kidney disease: the evolving story. Authors' reply.
Renal Insufficiency, Chronic
Renalase in Haemodialysis Patients with Chronic Kidney Disease.
Renal Insufficiency, Chronic
Renalase is a novel renal hormone that regulates cardiovascular function.
Renal Insufficiency, Chronic
Renalase, a new renal hormone: its role in health and disease.
Renal Insufficiency, Chronic
Renalase-specific polyclonal antibody and its application in the detection of renalase's expression.
Renal Insufficiency, Chronic
Renoprotection Provided by Additional Diuretic Treatment in Partially Nephrectomized Ren-2 Transgenic Rats Subjected to the Combined RAS and ETA Blockade.
Renal Insufficiency, Chronic
Role of renalase in the regulation of blood pressure and the renal dopamine system.
Renal Insufficiency, Chronic
Serum renalase is related to catecholamine levels and renal function.
Renal Insufficiency, Chronic
Serum-to-urine renalase ratio and renalase fractional excretion in healthy adults and chronic kidney disease patients.
Renal Insufficiency, Chronic
Sex-linked differences in the course of chronic kidney disease and congestive heart failure: a study in 5/6 nephrectomized Ren-2 transgenic hypertensive rats with volume overload induced using aorto-caval fistula.
Renal Insufficiency, Chronic
Synergistic effect of renalase and chronic kidney disease on endothelin-1 in patients with coronary artery disease ? a cross-sectional study.
Renal Insufficiency, Chronic
[Renalase and its role in the development of hypertension in patients with chronic renal failure].
renalase deficiency
Denervation-induced muscle atrophy suppression in renalase-deficient mice via increased protein synthesis.
renalase deficiency
Effects of renalase deficiency on liver fibrosis markers in a nonalcoholic steatohepatitis mouse model.
renalase deficiency
Human renalase: a review of its biology, function, and implications for hypertension.
renalase deficiency
Low plasma renalase concentration in hypertensive patients after surgical repair of coarctation of aorta.
renalase deficiency
Novel insights into the physiology of renalase and its role in hypertension and heart disease.
renalase deficiency
Plasma renalase in chronic kidney disease: differences and similarities between humans and rats.
renalase deficiency
Renalase deficiency in chronic kidney disease, and its contribution to hypertension and cardiovascular disease.
renalase deficiency
Renalase deficiency in heart failure model of rats--a potential mechanism underlying circulating norepinephrine accumulation.
renalase deficiency
Renalase gene polymorphism and epinephrine level in chronic kidney disease.
renalase deficiency
Renalase is Removed by Kidneys and During Dialysis - Excess Related to CKD Complications?
renalase deficiency
Role of renalase in the regulation of blood pressure and the renal dopamine system.
renalase deficiency
[Renalase and its role in the development of hypertension in patients with chronic renal failure].
Reperfusion Injury
Renalase as a Novel Biomarker for Evaluating the Severity of Hepatic Ischemia-Reperfusion Injury.
Reperfusion Injury
Renalase contributes to the renal protection of delayed ischaemic preconditioning via the regulation of hypoxia-inducible factor-1?.
Reperfusion Injury
Renalase protects the cardiomyocytes of Sprague-Dawley rats against ischemia and reperfusion injury by reducing myocardial cell necrosis and apoptosis.
Sleep Apnea Syndromes
Renalase and hypertension-demographic and clinical correlates in obstructive sleep apnea.
Sleep Apnea, Obstructive
Renalase and hypertension-demographic and clinical correlates in obstructive sleep apnea.
Sleep Bruxism
The Relationship between Sleep Bruxism Intensity and Renalase Concentration-An Enzyme Involved in Hypertension Development.
Starvation
Expression of the mouse ren-2 gene in the small intestine is regulated by food intake.
Stroke
An association study on renalase polymorphisms and ischemic stroke in a Chinese population.
Stroke
Exercise training prevents development of cardiac contractile dysfunction in hypertensive TG (mREN-2)27 rats.
Stroke
Load-sensitive measures may overestimate global systolic function in the presence of left ventricular hypertrophy: a comparison with load-insensitive measures.
Stroke
Novel insights into the physiology of renalase and its role in hypertension and heart disease.
Stroke
Renalase gene polymorphisms in patients with type 2 diabetes, hypertension and stroke.
Stroke
Serum Renalase Levels Are Predicted by Brain-Derived Neurotrophic Factor and Associated with Cardiovascular Events and Mortality after Percutaneous Coronary Intervention.
Ureteral Obstruction
Renalase contributes to protection against renal fibrosis via inhibiting oxidative stress in rats.
Ureteral Obstruction
Renalase Protects against Renal Fibrosis by Inhibiting the Activation of the ERK Signaling Pathways.
Ventricular Dysfunction
A functional polymorphism in renalase (Glu37Asp) is associated with cardiac hypertrophy, dysfunction, and ischemia: data from the heart and soul study.
Whooping Cough
Nifedipine-sensitive blood pressure component in hypertensive models characterized by high activity of either sympathetic nervous system or renin-angiotensin system.
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