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Reference on EC 1.5.1.8 - saccharopine dehydrogenase (NADP+, L-lysine-forming)

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Davis, A.T.
Assay for lysine-ketoglutarate reductase by reversed-phase high-performance liquid chromatography
J. Chromatogr.
497
263-267
1989
Rattus norvegicus
Manually annotated by BRENDA team
Arruda, P.; Sodek, L.; Da Silva, W.J.
Lysine-ketoglutarate reductase activity in developing maize endosperm
Plant Physiol.
69
988-989
1982
Zea mays
Manually annotated by BRENDA team
Arruda, P.; Da Silva, W.J.
Lysine-ketoglutarate reductase activity in maize: Its possible role in lysine metabolism of developing endosperm
Phytochemistry
22
2687-2689
1983
Zea mays
-
Manually annotated by BRENDA team
Noda, C.; Ichihara, A.
Purification and properties of L-lysine-alpha-ketoglutarate reductase from rat liver mitochondria
Biochim. Biophys. Acta
525
307-313
1978
Rattus norvegicus, Rattus norvegicus male Wistar
Manually annotated by BRENDA team
Fjellstedt, T.A.; Robinson, J.C.
Purification and properties of L-lysine-alpha-ketoglutarate reductase from human placenta
Arch. Biochem. Biophys.
168
536-548
1975
Homo sapiens
Manually annotated by BRENDA team
Hutzler, J.; Dancis, J.
Lysine-ketoglutarate reductase in human tissues
Biochim. Biophys. Acta
377
42-51
1975
Homo sapiens
Manually annotated by BRENDA team
Hutzler, J.; Dancis, J.
Conversion of lysine to saccharopine by human tissues
Biochim. Biophys. Acta
158
62-69
1968
Homo sapiens
Manually annotated by BRENDA team
Fellows, F.C.I.; Lewis, M.H.R.
Lysine metabolism in mammals
Biochem. J.
136
329-334
1973
Bos taurus, Canis lupus familiaris, Felis catus, Homo sapiens, Ovis aries, Rattus norvegicus, Rattus norvegicus Wistar, Sus scrofa
Manually annotated by BRENDA team
Markovitz, P.J.; Chuang, D.T.; Cox, R.P.
Familial hyperlysinemias. Purification and characterization of the bifunctional aminoadipic semialdehyde synthase with lysine-ketoglutarate reductase and saccharopine dehydrogenase activities
J. Biol. Chem.
259
11643-11646
1984
Bos taurus, Homo sapiens, Papio sp.
Manually annotated by BRENDA team
Markovitz, P.J.; Chuang, D.T.
The bifunctional aminoadipic semialdehyde synthase in lysine degradation. Separation of reductase and dehydrogenase domains by limited proteolysis and column chromatography
J. Biol. Chem.
262
9353-9358
1987
Bos taurus, Saccharomyces cerevisiae, Homo sapiens, Neurospora sp.
Manually annotated by BRENDA team
Blemings, K.P.; Crenshaw, T.D.; Swick, R.W.; Benevenga, N.J.
Lysine-alpha-ketoglutarate reductase and saccharopine dehydrogenase are located only in the mitochondrial matrix in rat liver
J. Nutr.
124
1215-1221
1994
Rattus norvegicus
Manually annotated by BRENDA team
Gaziola, S.A.; Sodek, L.; Arruda, P.; Lea, P.J.; Azevedo, R.A.
Degradation of lysine in rice seeds: Effect of calcium, ionic strength, S-adenosylmethionine and S-2-aminoethyl-L-cysteine on the lysine 2-oxoglutarate reductase-saccharopine dehydrogenase bifunctional enzyme
Physiol. Plant.
110
164-171
2000
Arabidopsis thaliana, Oryza sativa, Zea mays, Oryza sativa IAC 165
-
Manually annotated by BRENDA team
Zhu, X.; Tang, G.; Galili, G.
The catabolic function of the alpha-aminoadipic acid pathway in plants is associated with unidirectional activity of lysine-oxoglutarate reductase, but not saccharopine dehydrogenase
Biochem. J.
351
215-220
2000
Arabidopsis thaliana, Saccharomyces cerevisiae
Manually annotated by BRENDA team
Kemper, E.L.; Cord-Neto, G.; Capella, A.N.; Goncalves-Butruile, M.; Azevedo, R.; Arruda, P.
Structure and regulation of the bifunctional enzyme lysine-oxoglutarate reductase-saccharopine dehydrogenase in maize
Eur. J. Biochem.
253
720-729
1998
Saccharomyces cerevisiae, Nicotiana tabacum, Zea mays
Manually annotated by BRENDA team
Gaziola, S.A.; Teixeira, C.M.; Lugli, J.; Sodek, L.; Azevedo, R.A.
The enzymology of lysine catabolism in rice seeds. Isolation, characterization, and regulatory properties of a lysine 2-oxoglutarate reductase/saccharopine dehydrogenase bifunctional polypeptide
Eur. J. Biochem.
247
364-371
1997
Oryza sativa, Oryza sativa IAC 165
Manually annotated by BRENDA team
Miron, D.; Ben-Yaacov, S.; Karchi, H.; Galili, G.
In vitro dephosphorylation inhibits the activity of soybean lysine-ketoglutarate reductase in a lysine-regulated manner
Plant J.
12
1453-1458
1997
Glycine max, Nicotiana tabacum
-
Manually annotated by BRENDA team
Epelbaum, S.; McDevitt, R.; Falco, S.C.
Lysine-ketoglutarate reductase and saccharopine dehydrogenase from Arabidopsis thaliana: Nucleotide sequence and characterization
Plant Mol. Biol.
35
735-748
1997
Arabidopsis thaliana, Nicotiana tabacum
Manually annotated by BRENDA team
Moulin, M.; Deleu, C.; Larher, F.
L-Lysine catabolism is osmo-regulated at the level of lysine-ketoglutarate reductase and saccharopine dehydrogenase in rapeseed leaf discs
Plant Physiol. Biochem.
38
577-585
2000
Brassica napus
-
Manually annotated by BRENDA team
Miron, D.; Ben-Yaacov, S.; Reches, D.; Schupper, A.; Galili, G.
Purification and characterization of bifunctional lysine-ketoglutarate reductase/saccharopine dehydrogenase from developing soybean seeds
Plant Physiol.
123
655-663
2000
Glycine max, Oryza sativa, Zea mays
Manually annotated by BRENDA team
Tang, G.; Miron, D.; Zhu-Shimoni, J.X.; Galili, G.
Regulation of lysine catabolism through lysine-ketoglutarate reductase and saccharopine dehydrogenase in Arabidopsis
Plant Cell
9
1305-1316
1997
Arabidopsis thaliana, Saccharomyces cerevisiae
Manually annotated by BRENDA team
Cunha Lima, S.T.; Azevedo, R.A.; Santoro, L.G.; Gaziola, S.A.; Lea, P.J.
Isolation of the bifunctional enzyme lysine 2-oxoglutarate reductase-saccharopine dehydrogenase from Phaseolus vulgaris
Amino Acids
24
179-186
2003
Phaseolus vulgaris
Manually annotated by BRENDA team
Azevedo, R.A.; Damerval, C.; Landry, J.; Lea, P.J.; Bellato, C.M.; Meinhardt, L.W.; Le Guilloux, M.; Delhaye, S.; Toro, A.A.; Gaziola, S.A.; Berdejo, B.D.A.
Regulation of maize lysine metabolism and endosperm protein synthesis by opaque and floury mutations
Eur. J. Biochem.
270
4898-4908
2003
Zea mays
Manually annotated by BRENDA team
Fornazier, R.F.; Gaziola, S.A.; Helm, C.V.; Lea, P.J.; Azevedo, R.A.
Isolation and characterization of enzymes involved in lysine catabolism from sorghum seeds
J. Agric. Food Chem.
53
1791-1798
2005
Sorghum bicolor, Sorghum bicolor Moench
Manually annotated by BRENDA team
Manangi, M.K.; Hoewing, S.F.A.; Engels, J.G.; Higgins, A.D.; Killefer, J.; Wilson, M.E.; Blemings, K.P.
Lysine aLPHA-ketoglutarate reductase and lysine oxidation are distributed in the extrahepatic tissues of chickens
J. Nutr.
135
81-85
2005
Gallus gallus
Manually annotated by BRENDA team
Stepansky, A.; Galili, G.
Synthesis of the Arabidopsis bifunctional lysine-ketoglutarate reductase/saccharopine dehydrogenase enzyme of lysine catabolism is concertedly regulated by metabolic and stress-associated signals
Plant Physiol.
133
1407-1415
2003
Arabidopsis sp.
Manually annotated by BRENDA team
Battur, B.; Boldbaatar, D.; Umemiya-Shirafuji, R.; Liao, M.; Battsetseg, B.; Taylor, D.; Baymbaa, B.; Fujisaki, K.
LKR/SDH plays important roles throughout the tick life cycle including a long starvation period
PLoS ONE
4
e7136
2009
Haemaphysalis longicornis
Manually annotated by BRENDA team
Umair, S.; Bland, R.J.; Simpson, H.V.
Lysine catabolism in Haemonchus contortus and Teladorsagia circumcincta
Exp. Parasitol.
131
101-106
2012
Haemonchus contortus, Teladorsagia circumcincta
Manually annotated by BRENDA team
Schmidt, D.; Rizzi, V.; Gaziola, S.A.; Medici, L.O.; Vincze, E.; Kozak, M.; Lea, P.J.; Azevedo, R.A.
Lysine metabolism in antisense C-hordein barley grains
Plant Physiol. Biochem.
87
73-83
2015
Hordeum vulgare
Manually annotated by BRENDA team
Wan, P.; Yuan, S.; Tang, Y.; Li, K.; Yang, L.; Fu, Q.; Li, G.
Pathways of amino acid degradation in Nilaparvata lugens (Stal) with special reference to lysine-ketoglutarate reductase/saccharopine dehydrogenase (LKR/SDH)
PLoS ONE
10
e0127789
2015
Nilaparvata lugens (A0A089MUZ6), Nilaparvata lugens
Manually annotated by BRENDA team
Arruda, P.; Barreto, P.
Lysine catabolism through the saccharopine pathway enzymes and intermediates involved in plant responses to abiotic and biotic stress
Front. Plant Sci.
11
587
2020
Arabidopsis thaliana (Q9SMZ4), Brassica napus (Q9FVF4), Homo sapiens (Q9UDR5), Oryza sativa (A0A0K0K9B1), Zea mays (A0A3L6FCN0)
Manually annotated by BRENDA team