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Information on EC 1.5.1.3 - dihydrofolate reductase and Organism(s) Lactobacillus casei and UniProt Accession P00381

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EC Tree
     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.1 With NAD+ or NADP+ as acceptor
                1.5.1.3 dihydrofolate reductase
IUBMB Comments
The enzyme from animals and some micro-organisms also slowly reduces folate to 5,6,7,8-tetrahydrofolate.
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Lactobacillus casei
UNIPROT: P00381
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Word Map
The enzyme appears in selected viruses and cellular organisms
Synonyms
dhfr, dihydrofolate reductase, thy-1, dhfr-ts, hdhfr, dihydrofolate reductase-thymidylate synthase, ecdhfr, pcdhfr, r67 dhfr, ts-dhfr, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
7,8-dihydrofolate reductase
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-
-
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dehydrogenase, tetrahydrofolate
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-
-
-
DHFR
-
-
-
-
DHFR type IIIC
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-
-
-
dihydrofolate reductase-thymidylate synthase
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-
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dihydrofolate reductase:thymidylate synthase
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-
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dihydrofolic acid reductase
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-
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dihydrofolic reductase
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-
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folic acid reductase
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-
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folic reductase
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-
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NADPH-dihydrofolate reductase
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-
-
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pteridine reductase:dihydrofolate reductase
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-
-
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reductase, dihydrofolate
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-
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tetrahydrofolate dehydrogenase
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-
-
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thymidylate synthetase-dihydrofolate reductase
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-
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Trimethoprim resistance protein
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-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
redox reaction
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oxidation
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reduction
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PATHWAY SOURCE
PATHWAYS
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-, -, -, -
SYSTEMATIC NAME
IUBMB Comments
5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase
The enzyme from animals and some micro-organisms also slowly reduces folate to 5,6,7,8-tetrahydrofolate.
CAS REGISTRY NUMBER
COMMENTARY hide
9002-03-3
-
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
DYR_LACCA
163
0
18439
Swiss-Prot
-