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EC Tree
The taxonomic range for the selected organisms is: Daboia siamensis
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
laao, il4i1, l-amino-acid oxidase, l-aao, escapin, head kidney and gill, dolabellanin, l-phenylalanine oxidase, akbu-laao, m-lao,
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aromatic L-amino acid oxidase
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L-amino acid oxidase
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L-amino acid:O2 oxidoreductase
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ophio-amino-acid oxidase
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oxidative deamination
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KEGG
Alanine, aspartate and glutamate metabolism, Biosynthesis of secondary metabolites, Cysteine and methionine metabolism, Isoquinoline alkaloid biosynthesis, Phenylalanine metabolism, Phenylalanine, tyrosine and tryptophan biosynthesis, Tryptophan metabolism, Tyrosine metabolism, Valine, leucine and isoleucine degradation
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L-amino-acid:oxygen oxidoreductase (deaminating)
A flavoprotein (FAD).
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L-Ile + H2O + O2
3-methyl-2-oxopentanoate + NH3 + H2O2
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L-Leu + H2O + O2
4-methyl-2-oxopentanoic acid + NH3 + H2O2
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L-Phe + H2O + O2
phenylpyruvate + NH3 + H2O2
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additional information
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additional information
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LAAO dose-dependently inhibits platelet aggregation and exhibits antibactericidal activity
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additional information
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substrate specificity, overview. No activity with L-Pro, L-Asn, Gly, L-Ser, and L-Cys. The enzyme shows no hemorrhagic activity
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additional information
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LAAO dose-dependently inhibits platelet aggregation and exhibits antibactericidal activity
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UniProt
brenda
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brenda
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venom
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brenda
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OXLA_DABSI
407
0
46372
Swiss-Prot
other Location (Reliability: 1)
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58000
2 * 58000, SDS-PAGE
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homodimer
2 * 58000, SDS-PAGE
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native enzyme by anion exchange chromatography, gel filtration, and heparin affinity chromatography to homogeneity
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Zhong, S.R.; Jin, Y.; Wu, J.B.; Jia, Y.H.; Xu, G.L.; Wang, G.C.; Xiong, Y.L.; Lu, Q.M.
Purification and characterization of a new L-amino acid oxidase from Daboia russellii siamensis venom
Toxicon
54
763-771
2009
Daboia siamensis (Q4F867)
brenda
1.4.3.2 L-amino-acid oxidase
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The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). 
