Information on EC 1.3.99.38 - menaquinone-9 beta-reductase

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The expected taxonomic range for this enzyme is: Mycobacterium

EC NUMBER
COMMENTARY hide
1.3.99.38
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RECOMMENDED NAME
GeneOntology No.
menaquinone-9 beta-reductase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
menaquinone-9 + reduced acceptor = beta-dihydromenaquinone-9 + acceptor
show the reaction diagram
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
redox reaction
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
omega-sulfo-II-dihydromenaquinone-9 biosynthesis
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SYSTEMATIC NAME
IUBMB Comments
menaquinone-9 oxidoreductase (beta-dihydromenaquinone-9-forming)
The enzyme from the bacterium Mycobacterium tuberculosis reduces the beta-isoprene unit of menaquinone-9, forming the predominant form of menaquinone found in mycobacteria. Contains FAD.
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
menaquinone-9 + reduced acceptor
beta-dihydromenaquinone-9 + acceptor
show the reaction diagram
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
expressed in Escherichia coli BL21
ENGINEERING
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
pharmacology