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Information on EC 1.3.1.70 - DELTA14-sterol reductase

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EC Tree
IUBMB Comments
This enzyme acts on a range of steroids with a 14(15)-double bond.
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
lamin b receptor, tm7sf2, erg24, 14-reductase, sterol c-14 reductase, dhcr14, fackel, c14sr, delta14-reductase, fk-j3158, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + NADP+ = 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + NADPH + H+
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