Reference on EC 1.2.4.4 - 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Reed, L.J.; Damuni, Z.; Merryfield, M.L.
Regulation of mammalian pyruvate and branched-chain alpha-keto acid dehydrogenase complexes by phosphorylation-dephosphorylation
Curr. Top. Cell. Regul.
27
41-49
1985
Bos taurus
Aevarsson, A.; Chuang, J.L.; Wynn, R.M.; Turley, S.; Chuang, D.T.; Hol, W.G.J.
Crystal structure of human branched-chain alpha-ketoacid dehydrogenase and the molecular basis of multienzyme complex deficiency in maple syrup urine disease
Structure
8
277-291
2000
Homo sapiens
Randle, P.J.; Patston, P.A.; Espinal, J.
Branched-chain ketoacid dehydrogenase
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
18
97-121
1987
Bos taurus, Oryctolagus cuniculus, Rattus norvegicus
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Sykes, P.J.; Burns, G.; Menard, J.; Hatter, K.; Sokatch, J.R.
Molecular cloning of genes encoding branched-chain keto acid dehydrogenase of Pseudomonas putida
J. Bacteriol.
169
1619-1625
1987
Pseudomonas putida
Sykes, P.J.; Sokatch, J.R.
Cloning of genes for branched-chain keto acid dehydrogenase in Pseudomonas putida
Methods Enzymol.
166
350-359
1988
Pseudomonas putida
Chuang, J.L.; Cox, R.P.; Chuang, D.T.
Molecular cloning of the mature E1b-beta subunit of human branched-chain alpha-keto acid dehydrogenase complex
FEBS Lett.
262
305-309
1990
Homo sapiens
Nobukuni, Y.; Mitsubuchi, H.; Endo, F.; Asaka, J.; Oyama, R.; Titani, K.; Matsuda, I.
Isolation and characterization of a complementary DNA clone coding for the E1 beta subunit of the bovine branched-chain alpha-ketoacid dehydrogenase complex: complete amino acid sequence of the precursor protein and its proteolytic processing
Biochemistry
29
1154-1160
1990
Bos taurus
Lau, K.S.; Cooper, A.J.L.; Chuang, D.T.
Inhibition of the bovine branched-chain 2-oxo acid dehydrogenase complex and its kinase by arylidenepyruvates
Biochim. Biophys. Acta
1038
360-366
1990
Bos taurus
Harris, R.A.; Kuntz, M.J.; Simpson, R.
Inhibition of branched-chain alpha-keto acid dehydrogenase kinase by alpha-chloroisocaproate
Methods Enzymol.
166
114-123
1988
Rattus norvegicus
Argiles, J.M.; Lopez-Soriano, F.J.
Oxidation of branched-chain amino acids in tumor-bearing rats
Biochem. Soc. Trans.
17
1044-1045
1989
Rattus norvegicus
Sokatch, J.R.
Purification of branched-chain keto acid dehydrogenase and lipoamide dehydrogenase-valine from Pseudomonas
Methods Enzymol.
166
342-350
1988
Pseudomonas aeruginosa, Pseudomonas putida
Chuang, D.T.
Assays for E1 and E2 components of the branched-chain keto acid dehydrogenase complex
Methods Enzymol.
166
146-154
1988
Bos taurus
Paxton, R.
Branched-chain alpha-keto acid dehydrogenase and its kinase from rabbit liver and heart
Methods Enzymol.
166
313-320
1988
Oryctolagus cuniculus
Pettit, F.H.; Reed, L.J.
Branched-chain alpha-keto acid dehydrogenase complex from bovine kidney
Methods Enzymol.
166
309-312
1988
Bos taurus
Cook, K.G.; Yeaman, S.J.
Purification, resolution, and reconstitution of branched-chain 2-keto acid dehydrogenase complex from bovine kidney
Methods Enzymol.
166
303-308
1988
Bos taurus
Danner, D.J.; Heffelfinger, S.C.
Isolation of branched-chain alpha-keto acid dehydrogenase as active complex from bovine liver
Methods Enzymol.
166
298-302
1988
Bos taurus
Beggs, M.; Randle, P.J.
Activity of branched-chain 2-oxo acid dehydrogenase complex in rat liver mitochondria and in rat liver
Biochem. J.
256
929-934
1988
Rattus norvegicus
Johnson, W.A.; Connelly, J.L.
Cellular localization and characterization of bovine liver branched-chain -keto acid dehydrogenases
Biochemistry
11
1967-1973
1972
Bos taurus
Parker, P.J.; Randle, P.J.
Partial purification and properties of branched-chain 2-oxo acid dehydrogenase of ox liver
Biochem. J.
171
751-757
1978
Bos taurus
Pettit, F.H.; Yeaman, S.J.; Reed, L.J.
Purification and characterization of branched chain alpha-keto acid dehydrogenase complex of bovine kidney
Proc. Natl. Acad. Sci. USA
75
4881-4885
1978
Bos taurus
Danner, D.J.; Katz Lemmon, S.; Besharse, J.C.; Elsas, L.J.
Purification and characterization of branched chain alpha-ketoacid dehydrogenase from bovine liver mitochondria
J. Biol. Chem.
254
5522-5526
1979
Bos taurus
Sokatch, J.R.; McCully, V.; Roberts, C.M.
Purification of a branched-chain keto acid dehydrogenase from Pseudomonas putida
J. Bacteriol.
148
647-652
1981
Pseudomonas putida
Ono, K.; Hakozaki, M.; Kimura, A.; Kochi, H.
Purification, resolution, and reconstitution of rat liver branched-chain alpha-keto acid dehydrogenase complex
J. Biochem.
101
19-27
1987
Rattus norvegicus
Shimomura, Y.; Paxton, R.; Ozawa, T.; Harris, R.A.
Purification of branched chain alpha-ketoacid dehydrogenase complex from rat liver
Anal. Biochem.
163
74-78
1987
Rattus norvegicus
Goodwin, G.W.; Gibboney, W.; Paxton, R.; Harris, R.A.; Lemons, J.A.
Activities of branched-chain amino acid aminotransferase and branched-chain 2-oxo acid dehydrogenase complex in tissues of maternal and fetal sheep
Biochem. J.
242
305-308
1987
Ovis aries
Paxton, R.; Scislowski, P.W.D.; Davis, E.J.; Harris, R.A.
Role of branched-chain 2-oxo acid dehydrogenase and pyruvate dehydrogenase in 2-oxobutyrate metabolism
Biochem. J.
234
295-303
1986
Rattus norvegicus
McCully, V.; Burns, G.; Sokatch, J.R.
Resolution of branched-chain oxo acid dehydrogenase complex of Pseudomonas aeruginosa PAO
Biochem. J.
233
737-742
1986
Pseudomonas aeruginosa
Morrison, E.Y.S.A.; Mullings, K.
Isolation of a branched chain alpha-keto acid dehydrogenase from rabbit liver
Biochim. Biophys. Acta
755
225-228
1983
Oryctolagus cuniculus
Paxton, R.; Harris, R.A.
Isolation of rabbit liver branched chain alpha-ketoacid dehydrogenase and regulation by phosphorylation
J. Biol. Chem.
257
14433-14439
1982
Oryctolagus cuniculus
Paul, H.S.; Adibi, S.A.
Activation of hepatic branched chain alpha-keto acid dehydrogenase by a skeletal muscle factor
J. Biol. Chem.
257
12581-12588
1982
Rattus norvegicus
Danner, D.J.; Lemmon, S.K.; Elsas, L.J.
Stabilization of mammalian liver branched-chain alpha-ketoacid dehydrogenase by thiamin pyrophosphate
Arch. Biochem. Biophys.
202
23-28
1980
Bos taurus
Gerbling, H.; Gerhardt, B.
Oxidative decarboxylation of branched-chain 2-oxo fatty acids by higher plant peroxisomes
Plant Physiol.
88
13-15
1988
Vigna radiata
Parker, P.J.; Randle, P.J.
Inactivation of rat heart branched-chain 2-oxoacid dehydrogenase complex by adenosine triphosphate
FEBS Lett.
95
153-156
1978
Rattus norvegicus
Danner, D.J.; Davidson, E.D.; Elsas, L.J.
Thiamine increases the specific activity of human liver branched chain alpha-ketoacid dehydrogenase
Nature
254
529-530
1975
Homo sapiens
Parker, P.J.; Randle, P.J.
Branched chain 2-oxo-acid dehydrogenase complex of rat liver
FEBS Lett.
90
183-186
1978
Rattus norvegicus
Sinclair, D.A.; Dawes, I.W.; Dickinson, J.R.
Purification and characterization of the branched chain alpha-ketoacid dehydrogenase complex from Saccharomyces cerevisiae
Biochem. Mol. Biol. Int.
31
911-922
1993
Saccharomyces cerevisiae
Dickinson, J.R.
Branched-chain keto acid dehydrogenase of yeast
Methods Enzymol.
324
389-398
2000
Saccharomyces cerevisiae
Hester, K.L.; Luo, J.; Sokatch, J.R.
Purification of Pseudomonas putida branched-chain keto acid dehydrogenase E1 component
Methods Enzymol.
324
129-138
2000
Pseudomonas putida
Denoya, C.D.; Fedechko, R.W.; Hafner, E.W.; McArthur, H.A.; Morgenstern, M.R.; Skinner, D.D.; Stutzman-Engwall, K.; Wax, R.G.; Wernau, W.C.
A second branched-chain alpha-keto acid dehydrogenase gene cluster (bkdFGH) from Streptomyces avermitilis: its relationship to avermectin biosynthesis and the construction of a bkdF mutant suitable for the production of novel antiparasitic avermectins
J. Bacteriol.
177
3504-3511
1995
Streptomyces avermitilis
Ward, D.E.; Ross, R.P.; Van der Weijden, C.C.; Snoep, J.L.; Claiborne, A.L.
Catabolism of branched-chain alpha-keto acids in Enterococcus faecalis: the bkd gene cluster, enzymes, and metabolic route
J. Bacteriol.
181
5433-5442
1999
Enterococcus faecalis
Zhao, Y.; Hawes, J.; Popov, K.M.; Jaskiewicz, J.; Shimomura, Y.; Crabb, D.W.; Harris, R.A.
Site-directed mutagenesis of phosphorylation sites of the branched chain alpha-ketoacid dehydrogenase complex
J. Biol. Chem.
269
18583-18587
1994
Rattus norvegicus
Hester, K.; Luo, J.; Burns, B.; Braswell, E.H.; Sokatch, J.R.
Purification of active E1alpha2beta2 of Pseudomonas putida branched-chain-oxoacid dehydrogenase
Eur. J. Biochem.
233
828-836
1995
Pseudomonas putida
Aevarsson, A.; Seger, K.; Turley, S.; Sokatch, J.R.; Hol, W.G.J.
Crystal structure of 2-oxoisovalerate dehydrogenase and the architecture of 2-oxo acid dehydrogenase multienzyme complexes
Nat. Struct. Biol.
6
785-792
1999
Pseudomonas putida, Rattus norvegicus
Fujiki, Y.; Sato, T.; Ito, M.; Watanabe, A.
Isolation and characterization of cDNA clones for the E1beta and E2 subunits of the branched-chain alpha-ketoacid dehydrogenase complex in Arabidopsis
J. Biol. Chem.
275
6007-6013
2000
Arabidopsis thaliana
Hawes, J.W.; Schnepf, R.J.; Jenkins, A.E.; Shimomura, Y.; Popov, K.M.; Harris, R.A.
Roles of amino acid residues surrounding phosphorylation site 1 and branched-chain alpha-ketoacid dehydrogenase (BCKDH) in catalysis and phosphorylation site recognition by BCKDH kinase
J. Biol. Chem.
270
31071-31076
1995
Rattus norvegicus
Wynn, R.M.; Davie, J.R.; Chuang, J.L.; Cote, C.D.; Chuang, D.T.
Impaired assembly of E1 decarboxylase of the branched-chain alpha-ketoacid dehydrogenase complex in type IA maple syrup urine disease
J. Biol. Chem.
273
13110-13118
1998
Homo sapiens
Odessey, R.
Purification of rat kidney branched-chain oxo acid dehydrogenase complex with endogenous kinase activity
Biochem. J.
204
353-356
1982
Rattus norvegicus
Shiraki, M.; Shimomura, Y.; Miwa, Y.; Fukushima, H.; Murakami, T.; Tamura, T.; Tamura, N.; Moriwaki, H.
Activation of hepatic branched-chain alpha-keto acid dehydrogenase complex by tumor necrosis factor-alpha in rats
Biochem. Biophys. Res. Commun.
328
973-978
2005
Rattus norvegicus
Naik, M.T.; Chang, Y.C.; Huang, T.H.
Folding kinetics of the lipoic acid-bearing domain of human mitochondrial branched chain alpha-ketoacid dehydrogenase complex
FEBS Lett.
530
133-138
2002
Homo sapiens
Chang, C.F.; Chou, H.T.; Chuang, J.L.; Chuang, D.T.; Huang, T.H.
Solution structure and dynamics of the lipoic acid-bearing domain of human mitochondrial branched-chain alpha-keto acid dehydrogenase complex
J. Biol. Chem.
277
15865-15873
2002
Homo sapiens
Wynn, R.M.; Machius, M.; Chuang, J.L.; Li, J.; Tomchick, D.R.; Chuang, D.T.
Roles of His291-alpha and His146-beta' in the reductive acylation reaction catalyzed by human branched-chain alpha-ketoacid dehydrogenase: refined phosphorylation loop structure in the active site
J. Biol. Chem.
278
43402-43410
2003
Homo sapiens
Li, J.; Wynn, R.M.; Machius, M.; Chuang, J.L.; Karthikeyan, S.; Tomchick, D.R.; Chuang, D.T.
Cross-talk between thiamin diphosphate binding and phosphorylation loop conformation in human branched-chain alpha-keto acid decarboxylase/dehydrogenase
J. Biol. Chem.
279
32968-32978
2004
Homo sapiens
Nakai, T.; Nakagawa, N.; Maoka, N.; Masui, R.; Kuramitsu, S.; Kamiya, N.
Ligand-induced conformational changes and a reaction intermediate in branched-chain 2-oxo acid dehydrogenase (E1) from Thermus thermophilus HB8, as revealed by X-ray crystallography
J. Mol. Biol.
337
1011-1033
2004
Thermus thermophilus, Thermus thermophilus HB8 / ATCC 27634 / DSM 579
Li, L.; Thipyapong, P.; Breeden, D.C.; Steffens, J.C.
Overexpression of a bacterial branched-chain alpha-keto acid dehydrogenase complex in Arabidopsis results in accumulation of branched-chain acyl-CoAs and alteration of free amino acid composition in seeds
Plant Sci.
165
1213-1219
2003
Pseudomonas putida
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Naik, M.T.; Huang, T.H.
Conformational stability and thermodynamic characterization of the lipoic acid bearing domain of human mitochondrial branched chain alpha-ketoacid dehydrogenase
Protein Sci.
13
2483-2492
2004
Homo sapiens
Wynn, R.M.; Kato, M.; Machius, M.; Chuang, J.L.; Li, J.; Tomchick, D.R.; Chuang, D.T.
Molecular mechanism for regulation of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase complex by phosphorylation
Structure
12
2185-2196
2004
Homo sapiens
Murakami, T.; Matsuo, M.; Shimizu, A.; Shimomura, Y.
Dissociation of branched-chain alpha-keto acid dehydrogenase kinase (BDK) from branched-chain alpha-keto acid dehydrogenase complex (BCKDC) by BDK inhibitors
J. Nutr. Sci. Vitaminol.
51
48-50
2005
Rattus norvegicus
Nakai, N.; Shimomura, Y.; Tamura, T.; Tamura, N.; Hamada, K.; Kawano, F.; Ohira, Y.
Leucine-induced activation of translational initiation is partly regulated by the branched-chain alpha-keto acid dehydrogenase complex in C2C12 cells
Biochem. Biophys. Res. Commun.
343
1244-1250
2006
Mus musculus
Mersey, B.D.; Jin, P.; Danner, D.J.
Human microRNA (miR29b) expression controls the amount of branched chain alpha-ketoacid dehydrogenase complex in a cell
Hum. Mol. Genet.
14
3371-3377
2005
Homo sapiens
Sprusansky, O.; Stirrett, K.; Skinner, D.; Denoya, C.; Westpheling, J.
The bkdR gene of Streptomyces coelicolor is required for morphogenesis and antibiotic production and encodes a transcriptional regulator of a branched-chain amino acid dehydrogenase complex
J. Bacteriol.
187
664-671
2005
Streptomyces coelicolor
Chang, C.F.; Chou, H.T.; Lin, Y.J.; Lee, S.J.; Chuang, J.L.; Chuang, D.T.; Huang, T.H.
Structure of the subunit binding domain and dynamics of the di-domain region from the core of human branched chain alpha-ketoacid dehydrogenase complex
J. Biol. Chem.
281
28345-28353
2006
Homo sapiens
Brosnan, J.T.; Brosnan, M.E.
Branched-chain amino acids: enzyme and substrate regulation
J. Nutr.
136
207S-211S
2006
Homo sapiens
Shimomura, Y.; Honda, T.; Shiraki, M.; Murakami, T.; Sato, J.; Kobayashi, H.; Mawatari, K.; Obayashi, M.; Harris, R.A.
Branched-chain amino acid catabolism in exercise and liver disease
J. Nutr.
136
250S-253S
2006
Homo sapiens, Rattus norvegicus
Machius, M.; Wynn, R.M.; Chuang, J.L.; Li, J.; Kluger, R.; Yu, D.; Tomchick, D.R.; Brautigam, C.A.; Chuang, D.T.
A versatile conformational switch regulates reactivity in human branched-chain alpha-ketoacid dehydrogenase
Structure
14
287-298
2006
Homo sapiens
Madhusudhan, K.T.; Sokatch, J.R.
Purification of branched-chain keto acid dehydrogenase regulator from Pseudomonas putida
Methods Enzymol.
324
329-335
2000
Pseudomonas putida
Al-Mailem, D.M.; Hough, D.W.; Danson, M.J.
The 2-oxoacid dehydrogenase multienzyme complex of Haloferax volcanii
Extremophiles
12
89-96
2008
Haloferax volcanii
Heath, C.; Posner, M.G.; Aass, H.C.; Upadhyay, A.; Scott, D.J.; Hough, D.W.; Danson, M.J.
The 2-oxoacid dehydrogenase multi-enzyme complex of the archaeon Thermoplasma acidophilum - recombinant expression, assembly and characterization
FEBS J.
274
5406-5415
2007
Thermoplasma acidophilum
Kang, H.; Lee, S.K.; Cho, S.W.; Lee, S.H.; Kwack, K.
Branched chain alpha-keto acid dehydrogenase, E1-beta subunit gene is associated with premature ovarian failure
Fertil. Steril.
89
728-731
2008
Homo sapiens
Nakai, T.; Kuramitsu, S.; Kamiya, N.
Structural bases for the specific interactions between the E2 and E3 components of the Thermus thermophilus 2-oxo acid dehydrogenase complexes
J. Biochem.
143
747-758
2008
Thermus thermophilus
Islam, M.M.; Wallin, R.; Wynn, R.M.; Conway, M.; Fujii, H.; Mobley, J.A.; Chuang, D.T.; Hutson, S.M.
A novel branched-chain amino acid metabolon. Protein-protein interactions in a supramolecular complex
J. Biol. Chem.
282
11893-11903
2007
Rattus norvegicus (P35738)
Li, J.; Machius, M.; Chuang, J.L.; Wynn, R.M.; Chuang, D.T.
The two active sites in human branched-chain alpha-keto acid dehydrogenase operate independently without an obligatory alternating-site mechanism
J. Biol. Chem.
282
11904-11913
2007
Homo sapiens
Matsumoto, H.; Akita, K.; Sakai, R.; Shimomura, Y.
Analysis of branched-chain alpha-keto acid dehydrogenase complex activity in rat tissues using alpha-keto[1-13C]isocaproate as substrate
Anal. Biochem.
399
1-6
2010
Bos taurus, Rattus norvegicus
Skvorak, K.J.
Animal models of maple syrup urine disease
J. Inherit. Metab. Dis.
32
229-246
2009
Mus musculus
Bajotto, G.; Murakami, T.; Nagasaki, M.; Sato, Y.; Shimomura, Y.
Decreased enzyme activity and contents of hepatic branched-chain alpha-keto acid dehydrogenase complex subunits in a rat model for type 2 diabetes mellitus
Metab. Clin. Exp.
58
1489-1495
2009
Rattus norvegicus
Skvorak, K.J.; Paul, H.S.; Dorko, K.; Marongiu, F.; Ellis, E.; Chace, D.; Ferguson, C.; Gibson, K.M.; Homanics, G.E.; Strom, S.C.
Hepatocyte transplantation improves phenotype and extends survival in a murine model of intermediate maple syrup urine disease
Mol. Ther.
17
1266-1273
2009
Mus musculus
Knapik-Czajka, M.
Stimulation of rat liver branched-chain alpha-keto acid dehydrogenase activity by low doses of bezafibrate
Toxicology
306
101-107
2013
Rattus norvegicus
Cole, J.T.; Sweatt, A.J.; Hutson, S.M.
Expression of mitochondrial branched-chain aminotransferase and alpha-keto-acid dehydrogenase in rat brain: implications for neurotransmitter metabolism
Front. Neuroanat.
6
18
2012
Rattus norvegicus
Brautigam, C.A.; Wynn, R.M.; Chuang, J.L.; Naik, M.T.; Young, B.B.; Huang, T.H.; Chuang, D.T.
Structural and thermodynamic basis for weak interactions between dihydrolipoamide dehydrogenase and subunit-binding domain of the branched-chain alpha-ketoacid dehydrogenase complex
J. Biol. Chem.
286
23476-23488
2011
Homo sapiens
Knapik-Czajka, M.
Simvastatin increases liver branched-chain alpha-ketoacid dehydrogenase activity in rats fed with low protein diet
Toxicology
325
107-114
2014
Rattus norvegicus
Tso, S.C.; Qi, X.; Gui, W.J.; Chuang, J.L.; Morlock, L.K.; Wallace, A.L.; Ahmed, K.; Laxman, S.; Campeau, P.M.; Lee, B.H.; Hutson, S.M.; Tu, B.P.; Williams, N.S.; Tambar, U.K.; Wynn, R.M.; Chuang, D.T.
Structure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase
Proc. Natl. Acad. Sci. USA
110
9728-9733
2013
Mus musculus
Jia, F.; Cui, M.; Than, M.T.; Han, M.
Developmental defects of Caenorhabditis elegans lacking branched-chain alpha-ketoacid dehydrogenase are mainly caused by monomethyl branched-chain fatty acid deficiency
J. Biol. Chem.
291
2967-2973
2016
Caenorhabditis elegans
Lee, D.W.; Ng, B.G.; Kim, B.S.
Increased valinomycin production in mutants of Streptomyces sp. M10 defective in bafilomycin biosynthesis and branched-chain alpha-keto acid dehydrogenase complex expression
J. Ind. Microbiol. Biotechnol.
42
1507-1517
2015
Streptomyces sp., Streptomyces sp. M10
Kumaran, S.; Patel, M.S.; Jordan, F.
Nuclear magnetic resonance approaches in the study of 2-oxo acid dehydrogenase multienzyme complexes - a literature review
Molecules
18
11873-11903
2013
Escherichia coli
Kadota, Y.; Toyoda, T.; Kitaura, Y.; Adams, S.H.; Shimomura, Y.
Regulation of hepatic branched-chain alpha-ketoacid dehydrogenase complex in rats fed a high-fat diet
Obes. Res. Clin. Pract.
7
e439-e444
2013
Rattus norvegicus
Peng, C.; Uygun, S.; Shiu, S.H.; Last, R.L.
The impact of the branched-chain ketoacid dehydrogenase complex on amino acid homeostasis in Arabidopsis
Plant Physiol.
169
1807-1820
2015
Arabidopsis thaliana
Song, C.; Li, H.; Sheng, L.; Zhang, X.
Characterization of the interaction between superoxide dismutase and 2-oxoisovalerate dehydrogenase
Gene
568
1-7
2015
Thermus thermophilus (Q72GU1), Thermus thermophilus, Thermus thermophilus HB27 / ATCC BAA-163 / DSM 7039 (Q72GU1)
Cui, Q.; Zhou, F.; Liu, W.; Tao, Y.
Avermectin biosynthesis stable functional expression of branched chain alpha-keto acid dehydrogenase complex from Streptomyces avermitilis in Escherichia coli by selectively regulating individual subunit gene expression
Biotechnol. Lett.
39
1567-1574
2017
Streptomyces avermitilis
Knapik-Czajka, M.; Jurczyk, M.; Bielen, J.; Aleksandrovych, V.; Gawedzka, A.; Stach, P.; Drag, J.; Gil, K.
Effect of 5-fluorouracil on branched-chain alpha-keto acid dehydrogenase (BCKDH) complex in rats heart
Folia Med. Crac.
61
121-129
2021
Rattus norvegicus (P11960 and P35738)
Singh, V.K.; Sirobhushanam, S.; Ring, R.P.; Singh, S.; Gatto, C.; Wilkinson, B.J.
Roles of pyruvate dehydrogenase and branched-chain alpha-keto acid dehydrogenase in branched-chain membrane fatty acid levels and associated functions in Staphylococcus aureus
J. Med. Microbiol.
67
570-578
2018
Staphylococcus aureus, Staphylococcus aureus JE2
Hull, J.; Usmari Moraes, M.; Brookes, E.; Love, S.; Conway, M.
Distribution of the branched-chain alpha-ketoacid dehydrogenase complex E1alpha subunit and glutamate dehydrogenase in the human brain and their role in neuro-metabolism
Neurochem. Int.
112
49-58
2018
Homo sapiens (A0A024R0K3)
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