Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

BRENDA Home
show all | hide all No of entries

Information on EC 1.2.1.B23 - 4,4'-diaponeurosporen-aldehyde dehydrogenase

for references in articles please use BRENDA:EC1.2.1.B23
preliminary BRENDA-supplied EC number
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
Specify your search results
Select one or more organisms in this record: ?
This record set is specific for:
UNIPROT: A6QIE8 not found.
Show additional data
Do not include text mining results
Include (text mining) results
Include results (AMENDA + additional results, but less precise)
The expected taxonomic range for this enzyme is: Staphylococcus aureus
Synonyms
4,4'-diaponeurosporen-aldehyde dehydrogenase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
4,4'-diaponeurosporen-4-al + NAD(P)+ = 4,4'-diaponeurosporenoic acid + NAD(P)H + H+
show the reaction diagram
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
PATHWAY SOURCE
PATHWAYS
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
4,4'-diapolycopen-4'-al-4-oic acid + NAD(P)+
4,4'-diapolycopen-4,4'-dioic acid + NAD(P)H + H+
show the reaction diagram
-
-
-
?
4,4'-diapolycopen-4-al + NAD(P)+
4,4'-diapolycopenoic acid + NAD(P)H + H+
show the reaction diagram
-
-
-
?
4,4'-diapolycopenedial + NAD(P)+
4,4'-diapolycopen-4'-al-4-oic acid + NAD(P)H + H+
show the reaction diagram
-
-
-
?
4,4'-diaponeurosporen-4-al + NAD(P)+
4,4'-diaponeurosporenoic acid + NAD(P)H + H+
show the reaction diagram
-
-
-
?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
final enzyme in the biosynthetic pathway for staphyloxanthin, a C30 carotenoid biosynthesized by Staphylococcus aureus. Deletion of the gene abolishes staphyloxanthin biosynthesis and causes accumulation of 4,4'-diaponeurosporen-4-al. When the complete staphyloxanthin biosynthetic pathway is expressed using an artificial synthetic operon in Escherichia coli, staphyloxanthin-like compounds, which contain altered fatty acid acyl chains, and novel carotenoid compounds aere produced, indicating functional expression and coordination of the six staphyloxanthin pathway enzymes
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
A0A0H3KDU5_STAAE
Staphylococcus aureus (strain Newman)
459
0
51741
TrEMBL
-
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Kim, S.H.; Lee, P.C.
Functional expression and extension of staphylococcal staphyloxanthin biosynthetic pathway in Escherichia coli
J. Biol. Chem.
287
21575-21583
2012
Staphylococcus aureus (A0A0H3KDU5), Staphylococcus aureus
Manually annotated by BRENDA team