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Adenocarcinoma
Expression of ALDH3 and NMO1 in human corneal epithelial and breast adenocarcinoma cells.
Adenocarcinoma
Identification and characterization of a novel class 3 aldehyde dehydrogenase overexpressed in a human breast adenocarcinoma cell line exhibiting oxazaphosphorine-specific acquired resistance.
Adenocarcinoma
Overexpression or polycyclic aromatic hydrocarbon-mediated induction of an apparently novel class 3 aldehyde dehydrogenase in human breast adenocarcinoma cells and its relationship to oxazaphosphorine-specific acquired resistance.
Adenocarcinoma of Lung
[Expression of Acetaldehyde Dehydrogenase in Gefitinib-resistant Human Lung Adenocarcinoma HCC-827/GR Cells].
Adenocarcinoma of Lung
[Increased expression of acetaldehyde dehydrogenase in cisplatin-resistant human lung adenocarcinoma A549/DDP cells].
Alcohol Withdrawal Delirium
Some biochemical aspects of chronic alcohol intoxication.
aldehyde dehydrogenase [nad(p)+] deficiency
Associations of alcohol consumption and alcohol flush reaction with leukocyte telomere length in Korean adults.
aldehyde dehydrogenase [nad(p)+] deficiency
Why can't Chinese Han drink alcohol? Hepatitis B virus infection and the evolution of acetaldehyde dehydrogenase deficiency.
Anophthalmos
A Novel Missense Mutation in the ALDH13 Gene Causes Anophthalmia in Two Unrelated Iranian Consanguineous Families.
Asthma
Genetic determinants of both ethanol and acetaldehyde metabolism influence alcohol hypersensitivity and drinking behaviour among Scandinavians.
Asthma
Screening for acetaldehyde dehydrogenase 2 genotype in alcohol-induced asthma by using the ethanol patch test.
Asthma
The Pathogenesis of Alcohol-Induced Airflow Limitation in Acetaldehyde Dehydrogenase 2-Deficient Mice.
Bone Diseases, Metabolic
The Thiocarbamate Disulphide Drug, Disulfiram Induces Osteopenia in Rats by Inhibition of Osteoblast Function Due to Suppression of Acetaldehyde Dehydrogenase Activity.
Breast Neoplasms
Combined expression of aldehyde dehydrogenase 1A1 and ?-catenin is associated with lymph node metastasis and poor survival in breast cancer patients following cyclophosphamide treatment.
Breast Neoplasms
Oxazaphosphorine-specific resistance in human MCF-7 breast carcinoma cell lines expressing transfected rat class 3 aldehyde dehydrogenase.
Breast Neoplasms
Pivotal Role of AKT2 during Dynamic Phenotypic Change of Breast Cancer Stem Cells.
Carcinogenesis
Aldehyde dehydrogenases and cell proliferation.
Carcinogenesis
ALDH1A Isozymes are Markers of Human Melanoma Stem Cells and Potential Therapeutic Targets.
Carcinogenesis
ALDH2 modulates autophagy flux to regulate acetaldehyde-mediated toxicity thresholds.
Carcinogenesis
Possible role of acetaldehyde in ethanol-related rectal cocarcinogenesis in the rat.
Carcinogenesis
Structure of the 5' flanking region of class 3 aldehyde dehydrogenase in the rat.
Carcinogenesis
The role of acetaldehyde in alcohol-associated cancer of the gastrointestinal tract.
Carcinoma
Acetaldehyde breath test as a cancer risk marker in patients with esophageal and hypopharyngeal squamous cell carcinoma.
Carcinoma
Molecular genetics of human aldehyde dehydrogenase.
Carcinoma, Hepatocellular
Aldehyde dehydrogenase 3 expression is decreased by clofibrate via PPAR gamma induction in JM2 rat hepatoma cell line.
Carcinoma, Hepatocellular
Aldehyde dehydrogenase 3 gene regulation: studies on constitutive and hypoxia-modulated expression.
Carcinoma, Hepatocellular
Antisense oligonucleotides against aldehyde dehydrogenase 3 inhibit hepatoma cell proliferation by affecting MAP kinases.
Carcinoma, Hepatocellular
Biochemical genetic analysis of human and rodent aldehyde dehydrogenase (ALDH).
Carcinoma, Hepatocellular
Changes of CYP1A1, GST, and ALDH3 enzymes in hepatoma cell lines undergoing enhanced lipid peroxidation.
Carcinoma, Hepatocellular
Characteristics and aldehyde dehydrogenase activity of four rat hepatoma cell lines produced by diethylnitrosamine-phenobarbital treatment.
Carcinoma, Hepatocellular
Chromosome assignment, biochemical and immunological studies on a human aldehyde dehydrogenase, ALDH3.
Carcinoma, Hepatocellular
Comparative subcellular distribution of benzaldehyde and acetaldehyde dehydrogenase activities in two hepatoma cell lines and in normal hepatocytes.
Carcinoma, Hepatocellular
Comparison of expression of aldehyde dehydrogenase 3 and CYP1A1 in dominant and recessive aryl hydrocarbon hydroxylase-deficient mutant mouse hepatoma cells.
Carcinoma, Hepatocellular
Cytochemical detection of a class 3 aldehyde dehydrogenase in human hepatocellular carcinoma.
Carcinoma, Hepatocellular
Effects of hepatocarcinogenic initiators on aldehyde dehydrogenase gene expression in cultured rat hepatic cells.
Carcinoma, Hepatocellular
Expression of tumor-associated aldehyde dehydrogenase gene in rat hepatoma cell lines.
Carcinoma, Hepatocellular
Genetic variants of ALDH2-rs671 and CYP2E1-rs2031920 contributed to risk of hepatocellular carcinoma susceptibility in a Chinese population.
Carcinoma, Hepatocellular
Human stomach aldehyde dehydrogenase cDNA and genomic cloning, primary structure, and expression in Escherichia coli.
Carcinoma, Hepatocellular
Hypoxia exerts cell-type-specific effects on expression of the class 3 aldehyde dehydrogenase gene.
Carcinoma, Hepatocellular
Immunohistochemical study of hepatocellular carcinoma-specific aldehyde dehydrogenase.
Carcinoma, Hepatocellular
Induction of class 3 aldehyde dehydrogenase in the mouse hepatoma cell line Hepa-1 by various chemicals.
Carcinoma, Hepatocellular
Inhibition of cytosolic class 3 aldehyde dehydrogenase by antisense oligonucleotides in rat hepatoma cells.
Carcinoma, Hepatocellular
Primary structure of human hepatocellular carcinoma-associated aldehyde dehydrogenase.
Carcinoma, Hepatocellular
Purification and immunochemical characterization of aldehyde dehydrogenase from 2-acetylaminofluorene-induced rat hepatomas.
Carcinoma, Hepatocellular
The effect of a novel irreversible inhibitor of aldehyde dehydrogenases 1 and 3 on tumour cell growth and death.
Carcinoma, Hepatocellular
The subcellular distribution and properties of aldehyde dehydrogenase of hepatoma AH-130.
Cardiotoxicity
ALDH2 attenuates Dox-induced cardiotoxicity by inhibiting cardiac apoptosis and oxidative stress.
Cardiovascular Diseases
Acetaldehyde dehydrogenase 2 interactions with LDLR and AMPK regulate foam cell formation.
Cholangiocarcinoma
Loss of ARID1A induces a stemness gene ALDH1A1 expression with histone acetylation in the malignant subtype of cholangiocarcinoma.
Colitis
Protective Effects of ALDH1A Enzyme Inhibition on Helicobacter-Induced Colitis in Smad3-/- Mice are Associated with Altered ?4ß7 Integrin Expression on Activated T Cells.
Colitis, Ulcerative
Impairment of Tissue-Resident Mesenchymal Stem Cells in Chronic Ulcerative Colitis and Crohn's Disease.
Colonic Neoplasms
ALDH1A inhibition sensitizes colon cancer cells to chemotherapy.
Colorectal Neoplasms
ALDH1A inhibition sensitizes colon cancer cells to chemotherapy.
Colorectal Neoplasms
Targeting Colorectal Cancer Stem Cells as an Effective Treatment for Colorectal Cancer.
Coronary Artery Disease
The polymorphism in acetaldehyde dehydrogenase 2 gene, causing a substitution of Glu > Lys(504), is not associated with coronary atherosclerosis severity in Han Chinese.
Crohn Disease
Impairment of Tissue-Resident Mesenchymal Stem Cells in Chronic Ulcerative Colitis and Crohn's Disease.
Dermatitis, Atopic
Detection of down-regulated acetaldehyde dehydrogenase 1 in atopic dermatitis patients by two-dimensional electrophoresis.
Diabetes Mellitus
Protection of retinal function and morphology in MNU-induced retinitis pigmentosa rats by ALDH2: an in-vivo study.
Diabetic Retinopathy
ALDH2 attenuates early-stage STZ-induced aged diabetic rats retinas damage via Sirt1/Nrf2 pathway.
Endometriosis
Expression of ALDH1A Isozymes in Human Endometrium with and without Endometriosis and in Ovarian Endometrioma.
Esophageal Squamous Cell Carcinoma
Acetaldehyde breath test as a cancer risk marker in patients with esophageal and hypopharyngeal squamous cell carcinoma.
Essential Hypertension
Acetaldehyde dehydrogenase 2 SNP rs671 and susceptibility to essential hypertension in Mongolians: a case control study.
Fatty Liver
Role of hepatic acetaldehyde dehydrogenase in alcoholism: demonstration of persistent reduction of cytosolic activity in abstaining patients.
Fatty Liver
[Disulfiram-like reactions resulting from the administration of cephem antibiotics with methyltetrazolethiol moiety examined by using different doses]
Fatty Liver, Alcoholic
Aldehyde dehydrogenase (E.C. 1.2.1.3) in chronic alcoholic liver diseases.
Glioblastoma
[Adherent culture of CD133+ cells in glioblastomas and expression of ADLH1].
Glioma
High expression of ALDH1A3 might independently influence poor progression-free and overall survival in patients with glioma via maintaining glucose uptake and lactate production.
Hallucinations
Some biochemical aspects of chronic alcohol intoxication.
Head and Neck Neoplasms
A Novel Aldehyde Dehydrogenase-3 Activator (Alda-89) Protects Submandibular Gland Function from Irradiation without Accelerating Tumor Growth.
Heart Failure
Acetaldehyde dehydrogenase 2 deficiency exacerbates cardiac fibrosis by promoting mobilization and homing of bone marrow fibroblast progenitor cells.
Hepatitis B
Why can't Chinese Han drink alcohol? Hepatitis B virus infection and the evolution of acetaldehyde dehydrogenase deficiency.
Hepatitis, Alcoholic
Aldehyde dehydrogenase (E.C. 1.2.1.3) in chronic alcoholic liver diseases.
Hypersensitivity
Allergic and intolerance reactions to wine.
Hypertension
Acetaldehyde Dehydrogenase 2 rs671 Polymorphism Affects Hypertension Susceptibility and Lipid Profiles in a Chinese Population.
Hypertension
Association of a functional single-nucleotide polymorphism in the ALDH2 gene with essential hypertension depends on drinking behavior in a Chinese Han population.
Hypertension
Epidemiologic study of the association of low-Km mitochondrial acetaldehyde dehydrogenase genotypes with blood pressure level and the prevalence of hypertension in a general population.
Hypertension
[Effects of ethanol on the nervous and vascular systems: the mechanisms of alcohol-induced hypertension]
Infections
LAP, an alcohol acetaldehyde dehydrogenase enzyme in Listeria, promotes bacterial adhesion to enterocyte-like Caco-2 cells only in pathogenic species.
Infections
Secreted Listeria adhesion protein (Lap) influences Lap-mediated Listeria monocytogenes paracellular translocation through epithelial barrier.
Infections
[Improvement of combination chemotherapy tolerance of human umbilical cord blood CD(34)(+) cells transducted with double drug resistance genes by a bicistronic retroviral vector]
Iron Deficiencies
The Metabolic Status Drives Acclimation of Iron Deficiency Responses in Chlamydomonas reinhardtii as Revealed by Proteomics Based Hierarchical Clustering and Reverse Genetics.
Leukemia
Sphere-forming-like cells (squamospheres) with cancer stem-like cell traits from VX2 rabbit buccal squamous cell carcinoma.
Liver Cirrhosis, Alcoholic
Aldehyde dehydrogenase (E.C. 1.2.1.3) in chronic alcoholic liver diseases.
Liver Cirrhosis, Alcoholic
Hepatic Deficiency of Augmenter of Liver Regeneration Exacerbates Alcohol-Induced Liver Injury and Promotes Fibrosis in Mice.
Liver Diseases
Aldehyde dehydrogenase (E.C. 1.2.1.3) in chronic alcoholic liver diseases.
Melanoma
ALDH1A Isozymes are Markers of Human Melanoma Stem Cells and Potential Therapeutic Targets.
Melanoma
Malignant melanoma: diagnosis, treatment and cancer stem cells.
Myoma
Acetaldehyde differentially affects the growth of uterine leiomyomata and myometrial cells in tissue cultures.
Neoplasms
?,?-Acetylenic Amino Thiolester Inhibitors of Aldehyde Dehydrogenases 1&3: Suppressors of Apoptogenic Aldehyde Oxidation and Activators of Apoptosis.
Neoplasms
Alcohol drinking, cigarette smoking, and the development of squamous cell carcinoma of the esophagus: epidemiology, clinical findings, and prevention.
Neoplasms
Aldehyde dehydrogenase 3 converts farnesal into farnesoic acid in the corpora allata of mosquitoes.
Neoplasms
ALDH1A inhibition sensitizes colon cancer cells to chemotherapy.
Neoplasms
Antisense oligonucleotides against aldehyde dehydrogenase 3 inhibit hepatoma cell proliferation by affecting MAP kinases.
Neoplasms
Class 1 and class 3 aldehyde dehydrogenase levels in the human tumor cell lines currently used by the National Cancer Institute to screen for potentially useful antitumor agents.
Neoplasms
Comparison between self-reported facial flushing after alcohol consumption and ALDH2 Glu504Lys polymorphism for risk of upper aerodigestive tract cancer in a Japanese population.
Neoplasms
Development of 2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of aldehyde dehydrogenase 1A (ALDH1A) as potential adjuncts to ovarian cancer chemotherapy.
Neoplasms
Expression profile of intestinal stem cell and cancer stem cell markers in gastric cancers with submucosal invasion.
Neoplasms
Functional study of acetaldehyde dehydrogenase 1 (ALDH1) in keratinocytes: Microarray integrating bioinformatics approaches.
Neoplasms
Inhibition of cytosolic class 3 aldehyde dehydrogenase by antisense oligonucleotides in rat hepatoma cells.
Neoplasms
Inhibition of human class 3 aldehyde dehydrogenase, and sensitization of tumor cells that express significant amounts of this enzyme to oxazaphosphorines, by chlorpropamide analogues.
Neoplasms
Inhibition of human class 3 aldehyde dehydrogenase, and sensitization of tumor cells that express significant amounts of this enzyme to oxazaphosphorines, by the naturally occurring compound gossypol.
Neoplasms
Inhibitors of aldehyde dehydrogenases of the 1A subfamily as putative anticancer agents: Kinetic characterization and effect on human cancer cells.
Neoplasms
Integration of Inhibition Kinetics and Molecular Dynamics Simulations: A Urea-Mediated Folding Study on Acetaldehyde Dehydrogenase 1.
Neoplasms
Possible role of acetaldehyde in ethanol-related rectal cocarcinogenesis in the rat.
Neoplasms
Properties of lewis lung carcinoma cells surviving curcumin toxicity.
Neoplasms
Prostaglandin E2 receptor EP4 as the common target on cancer cells and macrophages to abolish angiogenesis, lymphangiogenesis, metastasis, and stem-like cell functions.
Neoplasms
Protein expression during lag phase and growth initiation in Saccharomyces cerevisiae.
Neoplasms
Regulatory T cells promote glioma cell stemness through TGF-?-NF-?B-IL6-STAT3 signaling.
Neoplasms
Role of Retinoic Acid-Metabolizing Cytochrome P450s, CYP26, in Inflammation and Cancer.
Neoplasms
Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy.
Neoplasms
Substrate preference of a cytosolic aldehyde dehydrogenase inducible in rat liver by treatment with 3-methylcholanthrene.
Neoplasms
The effect of genetic polymorphisms in the vinyl chloride metabolic pathway on mutagenic risk.
Neoplasms
The role of acetaldehyde in alcohol-associated cancer of the gastrointestinal tract.
Neoplasms
The role of acetaldehyde in upper digestive tract cancer in alcoholics.
Neoplasms
The role of hyperplastic nodules in dichloroacetic acid-induced hepatocarcinogenesis in B6C3F1 male mice.
Neoplasms
Tumor-associated aldehyde dehydrogenase (ALDH3): expression in different human tumor cell lines with and without treatment with 3-methylcholanthrene.
Neoplasms
[Expression of Acetaldehyde Dehydrogenase in Gefitinib-resistant Human Lung Adenocarcinoma HCC-827/GR Cells].
Obesity
Pharmacological inhibition of ALDH1A enzymes suppresses weight gain in a mouse model of diet-induced obesity.
Pneumonia
Deletion of ldhA and aldH genes in Klebsiella pneumoniae to enhance 1,3-propanediol production.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Aberrant expression of aldehyde dehydrogenase 1A (ALDH1A) subfamily genes in acute lymphoblastic leukaemia is a common feature of T-lineage tumours.
Prostatic Neoplasms
Aldehyde dehydrogenase inhibitors: alpha,beta-acetylenic N-substituted aminothiolesters are reversible growth inhibitors of normal epithelial but irreversible apoptogens for cancer epithelial cells from human prostate in culture.
Squamous Cell Carcinoma of Head and Neck
Acetaldehyde breath test as a cancer risk marker in patients with esophageal and hypopharyngeal squamous cell carcinoma.
Starvation
Ald6p is a preferred target for autophagy in yeast, Saccharomyces cerevisiae.
Stroke
ALDH2 attenuates early-stage STZ-induced aged diabetic rats retinas damage via Sirt1/Nrf2 pathway.
Tachycardia
Impact of Flushing Response on the Relationship between Alcohol Consumption and Gamma-glutamyl Transpeptidase: the KOBE study.
Vitiligo
Isolating RNA from precursor and mature melanocytes from human vitiligo and normal skin using laser capture microdissection.
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1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
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The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). 
